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Dealing with Complication of
Hysteroscopy
Dato DR ARUKU NAIDU
MD(UKM), FRCOG(LONDON), CU(JCU), AM
CONSULTANT O& G, UROGYNAECOLOGIST
Hosp Raja Permaisuri Bainun,
Sessional consultant Ipoh Specialist Hosp,
Honorary lecturer HUKM, Perak Med College
aruku-naidu.blogspot.com
Complication of Hysteroscopy
• Complication rate 2% ( Assoc. Gynaecologic
Laparoscopists, AAGL, 1993)
• Prospective randomize trial by Jansen et. Al,
13,600 procedures, Netherland
Diagnostic hysteroscopy: 0.13%
Operative hysteroscopy: 0.95%
Complication of hysteroscopy
(directly related )
• Cervical injury
• Uterine perforation
• Haemorrhage
• Infection
• Injury to bladder, bowel and blood vessels
• Thermal damage by electrical current
• Medical complications resulting from reactions
to drugs or anesthetic agents
- anaphylaxis
• Complications due to distending media
– CO2 : Acidosis, Arrhythmia, Embolism
– Dextran : Anaphylaxis, Pulmonary oedema
– NS: Pulmonary oedema, hyponatraemia
– Dextose : Pulmonary oedema, hypoglycaemia
Complication of hysteroscopy
( Indirect)
• Accidental perforation of the uterus is the
most common complication
• generally diagnosed by direct visualization
 suspected in cases of unexplained rapid increase
in the fluid deficit, uncontrolled hemorrhage, and
hemodynamic instability
1. UTERINE PERFORATION
UTERINE PERFORATION
• Can occur during:
– Cervical dilatation
– Surgery
– Retrieval of tissue
• Action:
– Observation
– Laparoscopy
– Laparotomy
Hemostatic uterus perforation
 By uterine sound, cervical dilator, hysteroscope, or blunt
instrument
 may be managed conservatively: scan to exclude
haemorrhage, antibiotics, iv oxytocin
Consider Laparoscopy/ Laparotomy if:
 Perforations through the posterior or lateral uterus
 sharp or electrocautery instruments
- In view of potential for injury to the pelvic viscera or vasculature
UTERINE PERFORATION
2. Haemorrhage
May be encountered during or after hysteroscopy.
Exclude uterine perforation 1st
Mild bleeding is typically self-limited and generally
does not require intervention
Electrocautery may be used to coagulate small vessels
If conservative approached failed:
 Foley catheter or intrauterine balloon can be inserted into the
cavity and inflated to tamponade the hemorrhage
 Packing of uterus with roller gauze +/- vasopressin
 IV oxytocin, inj vasopressin paracervical
 Rarely embolisation, ligation or hysterctomy
3. Injury to viscus/organs
 Bowel
 Bladder
 Omentum
 Lateral uterine wall ( Haematoma)
Can be detected immediately or post-op
Direct visualization with hysteroscopy
Presence of abd pain, fever, leucocytosis, pertonitis
after surgery= injury till proven other vice
Injury to viscus/organs
Bowel
The emanation of foul smelling gas through
pneumoperitoneal needle is a helpful diagnostic
sign
Minilaparotomy and repair of perforation
Laparoscopically, perforation may be sutured using
laparoscopic stapler
Colostomy
Injury to viscus/organs
Bladder
Diagnosis: appearance of blood and gas on
Foley’s catheter bag
Check cystoscopy….
Place an indwelling catheter for 7-10 days
Prophylaxis antibiotic
If defect is larger, repaired by a figure of 8 suture
through muscularis of bladder and second suture
to close peritoneum
Complication due to
Distending Media
1.Fluid Overload
2.Gases embolism ( Co2, Air)
Fluid overload may be
due to:
• Intravasation
• Transtubal loss
• Uterine perforation
1
2
3
1. Fluid Overload
Fluid overload may cause pulmonary edema
 Mostly occur in cases with excessive intravasation of
isotonic fluids
Mechanism of fluid overload
Uterine cavity- a potential space
Minimum pressure
• 30 mmHg to separate uterine walls
• 45-80 mmHg to expand uterine
cavity, rarely >100 mmHg
MAP ~ 100 mmHg
Fluid Overload ( 0.2%)
Electrolyte free distension media can cause rapid and
profound hyponatremia if absorbed in large quantities.
• Abrupt changes in the serum sodium level may cause
– altered mental status
– Seizures
– Coma
– Death
Action:
 If Na< 125, correct with Intravenous 3% sodium chloride
 furosemide should be used to achieve the appropriate
amount of diuresis.
FLUID MONITORING DURING
HYSTEROSCOPY
Inflow/outflow charts
Adjust intrauterine pressure
Measurement of serum Na+
Measurement of plasma osmolality
CVP measurement
Patient weight
2. CO2 Embolism
Symptoms of embolism
• A sudden decrease in PCO2, especially when
accompanied by a decrease in blood pressure
• A decrease in oxygen saturation
• Arrhythmias, tachycardia, Cardiovascular collapse
• Sustained hypotension not explained by
hypovolemia alone
• Electrocardiography changes
Electrocardiographic changes
 Bradycardia or tachycardia,
 Premature ventricular contractions
 Heart block
 ST-segment depression
ECG Monitoring
If suspected gas embolism (CO2):
• Rapid identification, stop procedure
• Prevention of further gas entrainment by
closing the point of air entry.
• give 100% oxygen
• Put the patient in a reverse
trendelenburg position
• The Durant maneuver- With this
maneuver the patient is placed on
the left side while using Trendelenburg
position
The complication are extremely rare if the correct
insufflator is used.
The hysteroflator delivers CO2 at a rate of not more
than 100ml per minute whereas the laparoflator
can deliver 1-6 litres in the same time
A laparoflater should NEVER be used for
hysteroscopy.
Prevention of gas embolism
Monitoring During Operating
Hysteroscopy
Standard monitoring
• pulse oximetry,
• 3-lead electrocardiography,
• blood pressure measurements
• PCO2 monitoring
• standard ventilatory monitoring.
• Strict inflow / out flow chart
Post operative complications
 Secondary haemorrhage, rare, haemataoma
 Infection ( 1-2%)= fever & pelvic pain with 72
hrs after hysteroscopy
 Thermal injuries(Adjacent organs)
presence of abd pain, fever, leucocytosis,
pertonitis after surgery= injury till proven
other vice
Conclusion
• Current hysteroscopic surgery is safe
• BUT complications are related to experience
of surgeons
• Proper instruments essential to reduce
complications
• Right distention media & right energy source
essential
• Proper training essential get good outcome &
reduce complications
THANK YOU

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Management of hysteroscopic complication

  • 1. Dealing with Complication of Hysteroscopy Dato DR ARUKU NAIDU MD(UKM), FRCOG(LONDON), CU(JCU), AM CONSULTANT O& G, UROGYNAECOLOGIST Hosp Raja Permaisuri Bainun, Sessional consultant Ipoh Specialist Hosp, Honorary lecturer HUKM, Perak Med College aruku-naidu.blogspot.com
  • 2. Complication of Hysteroscopy • Complication rate 2% ( Assoc. Gynaecologic Laparoscopists, AAGL, 1993) • Prospective randomize trial by Jansen et. Al, 13,600 procedures, Netherland Diagnostic hysteroscopy: 0.13% Operative hysteroscopy: 0.95%
  • 3. Complication of hysteroscopy (directly related ) • Cervical injury • Uterine perforation • Haemorrhage • Infection • Injury to bladder, bowel and blood vessels • Thermal damage by electrical current
  • 4. • Medical complications resulting from reactions to drugs or anesthetic agents - anaphylaxis • Complications due to distending media – CO2 : Acidosis, Arrhythmia, Embolism – Dextran : Anaphylaxis, Pulmonary oedema – NS: Pulmonary oedema, hyponatraemia – Dextose : Pulmonary oedema, hypoglycaemia Complication of hysteroscopy ( Indirect)
  • 5. • Accidental perforation of the uterus is the most common complication • generally diagnosed by direct visualization  suspected in cases of unexplained rapid increase in the fluid deficit, uncontrolled hemorrhage, and hemodynamic instability 1. UTERINE PERFORATION
  • 6. UTERINE PERFORATION • Can occur during: – Cervical dilatation – Surgery – Retrieval of tissue • Action: – Observation – Laparoscopy – Laparotomy
  • 7. Hemostatic uterus perforation  By uterine sound, cervical dilator, hysteroscope, or blunt instrument  may be managed conservatively: scan to exclude haemorrhage, antibiotics, iv oxytocin Consider Laparoscopy/ Laparotomy if:  Perforations through the posterior or lateral uterus  sharp or electrocautery instruments - In view of potential for injury to the pelvic viscera or vasculature UTERINE PERFORATION
  • 8. 2. Haemorrhage May be encountered during or after hysteroscopy. Exclude uterine perforation 1st Mild bleeding is typically self-limited and generally does not require intervention Electrocautery may be used to coagulate small vessels If conservative approached failed:  Foley catheter or intrauterine balloon can be inserted into the cavity and inflated to tamponade the hemorrhage  Packing of uterus with roller gauze +/- vasopressin  IV oxytocin, inj vasopressin paracervical  Rarely embolisation, ligation or hysterctomy
  • 9. 3. Injury to viscus/organs  Bowel  Bladder  Omentum  Lateral uterine wall ( Haematoma) Can be detected immediately or post-op Direct visualization with hysteroscopy Presence of abd pain, fever, leucocytosis, pertonitis after surgery= injury till proven other vice
  • 10. Injury to viscus/organs Bowel The emanation of foul smelling gas through pneumoperitoneal needle is a helpful diagnostic sign Minilaparotomy and repair of perforation Laparoscopically, perforation may be sutured using laparoscopic stapler Colostomy
  • 11. Injury to viscus/organs Bladder Diagnosis: appearance of blood and gas on Foley’s catheter bag Check cystoscopy…. Place an indwelling catheter for 7-10 days Prophylaxis antibiotic If defect is larger, repaired by a figure of 8 suture through muscularis of bladder and second suture to close peritoneum
  • 12. Complication due to Distending Media 1.Fluid Overload 2.Gases embolism ( Co2, Air)
  • 13. Fluid overload may be due to: • Intravasation • Transtubal loss • Uterine perforation 1 2 3 1. Fluid Overload Fluid overload may cause pulmonary edema  Mostly occur in cases with excessive intravasation of isotonic fluids
  • 14. Mechanism of fluid overload Uterine cavity- a potential space Minimum pressure • 30 mmHg to separate uterine walls • 45-80 mmHg to expand uterine cavity, rarely >100 mmHg MAP ~ 100 mmHg
  • 15. Fluid Overload ( 0.2%) Electrolyte free distension media can cause rapid and profound hyponatremia if absorbed in large quantities. • Abrupt changes in the serum sodium level may cause – altered mental status – Seizures – Coma – Death Action:  If Na< 125, correct with Intravenous 3% sodium chloride  furosemide should be used to achieve the appropriate amount of diuresis.
  • 16. FLUID MONITORING DURING HYSTEROSCOPY Inflow/outflow charts Adjust intrauterine pressure Measurement of serum Na+ Measurement of plasma osmolality CVP measurement Patient weight
  • 17. 2. CO2 Embolism Symptoms of embolism • A sudden decrease in PCO2, especially when accompanied by a decrease in blood pressure • A decrease in oxygen saturation • Arrhythmias, tachycardia, Cardiovascular collapse • Sustained hypotension not explained by hypovolemia alone • Electrocardiography changes
  • 18. Electrocardiographic changes  Bradycardia or tachycardia,  Premature ventricular contractions  Heart block  ST-segment depression ECG Monitoring
  • 19. If suspected gas embolism (CO2): • Rapid identification, stop procedure • Prevention of further gas entrainment by closing the point of air entry. • give 100% oxygen • Put the patient in a reverse trendelenburg position • The Durant maneuver- With this maneuver the patient is placed on the left side while using Trendelenburg position
  • 20. The complication are extremely rare if the correct insufflator is used. The hysteroflator delivers CO2 at a rate of not more than 100ml per minute whereas the laparoflator can deliver 1-6 litres in the same time A laparoflater should NEVER be used for hysteroscopy. Prevention of gas embolism
  • 21. Monitoring During Operating Hysteroscopy Standard monitoring • pulse oximetry, • 3-lead electrocardiography, • blood pressure measurements • PCO2 monitoring • standard ventilatory monitoring. • Strict inflow / out flow chart
  • 22. Post operative complications  Secondary haemorrhage, rare, haemataoma  Infection ( 1-2%)= fever & pelvic pain with 72 hrs after hysteroscopy  Thermal injuries(Adjacent organs) presence of abd pain, fever, leucocytosis, pertonitis after surgery= injury till proven other vice
  • 23. Conclusion • Current hysteroscopic surgery is safe • BUT complications are related to experience of surgeons • Proper instruments essential to reduce complications • Right distention media & right energy source essential • Proper training essential get good outcome & reduce complications