Albinism in humans is inherited as a simple recessive trait. For the.pdf

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Albinism is an inherited recessive trait in humans. A normal male and albino female had three normal and three albino children. The most likely genotypes of the parents are: the male is Aa (heterozygous) and the female is aa (homozygous recessive). Albinism is caused by the recessive a allele, so the female must be homozygous recessive aa to produce both albino and normal children when bred with a heterozygous male Aa.

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Albinism in humans is inherited as a simple recessive trait. For the following families, determine
the most likely genotypes of the parents. A normal male and an albino female have six children,
three normal and three albino. What are the most likely genotypes of the parents?
a.male AA; female aa
b.male AA; female Aa
c.male Aa; female aa
d.male Aa; female Aa
Solution
c.male Aa; female aa
Albinism is a homozygous recessive trait. Assume that the gene coding for normal phenotype is
A and the gene coding for albinism is a (A is normal and A is dominant over a), albinism is
inherited by a homozygous recessive pattern (aa).
It is given that an unaffected male and an affected female had both normal and affected children.
Means, the children receive one recessive allele from the mother and the other from the father.
Thus, the father is heterozygous (Aa) and the mother is homozygous recessive (aa).

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Hemophilia is a recessive trait. The dominant trait is normal blood dotting A gene that can cause hemophilia is located on the X chromosome. If a homozygous normal female marries a normal male, they children might have which of the following phenotypes: Select one: a. normal females, hemophiliac females, and hemophiliac males. b. normal females, hemophiliac females, normal males, and hemophiliac males. c. normal females and hemophiliac males d. normal females and normal mates. e. normal females, normal males or hemophiliac males. Solution In X - linked recessive inheritance males are more prone to disease because they carry the disease trait. If the affected offspring’s mother has brother or father containing the same trait then the mother pass the trait to her offspring. The affected males produce unaffected daughters who can produce 50% affected sons. Hemophilia is the example of X - linked recessive trait. When a homozygous normal female marries to a normal male the offspring produced are normal females and normal males. Option d is correct..

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2 3 4 5 Assignments \#1 Distinguish between the following genetic terms: A. Gene and allele. B. Homozygous and heterozygous. C. Genotype and phenotype. D. Dominant and recessive. 1. A man with red-green colour blindness is married to a girl with normal colour vision. What is the probability that his children will be colour blind? 2. A boy has Duchenne muscular dystrophy. His maternal uncle had died of muscular dystrophy at the age of 21 years. What is the probability that this child's sibs will be affected? Explain, giving reasons, whether the following pedigrees are compatible with autosomal dominant, autosomal recessive or X-linked dominant and X -linked recessive inheritance. (Note that a pedigree may be compatible with more than one type of inheritance.) a. b. c. a. b. c. Assignments \#4 Examine the pedigree from a family with a genetic disease and ansv the questions below: a. Does this pedigree indicate autosomal dominant, recessive or sex-link type of inheritance? Give reasons for your choice. b. Assuming that B and b are the normal and mutant alleles respectively what would be the genotypes of the individuals: II.I, II.2 and III.3? c. Individual II.3 requested genetic counselling. What is the probability that her child would be affected. Explain why. Susan's grandfather was deaf, and passed down a hereditary form of deafness within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant or recessive? B. Is it carried on an autosome or a sex chromosome? Why? C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected, and 7 unaffected). In comparing these 11 SNP results, how long a haplotype block would you expect to find around the critical gene? How might you detect it? .

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X-Linked Recessive Write three rules to keep in mind when counseling someone about the likelihood of inheriting an X-linked recessive condition: About parents\' genotype. About parents\' phenotype. About the probability of the offspring showing the trait. If instead of having Hemophilia C (autosomal recessive), Lisa Keller\'s brother had Hemophilia A (X-linked recessive), what would be the probability that she was a carrier? 25% 50% 67% 100% More information is required to answer this question. Solution About genotype of parents- If the mother is a carrier i.e. carrying the recessive allele on one of her X chromosome and the father do not have the recessive allele in his genotype, then none of the daughters will suffer from the disease (since they will inherit only one recessive allele from the mother) but sons will have a 50% probability of suffering from the disease as they will inherit the recessive allele from the mother and the Y chromosome from the father, although there is a 50% probability of inheriting the wild type allele from the mother. Now if the mother is suffering from the disease i.e. has the recessive allele on both the X chromosome while the father is healthy having no allele for the disease, the daughters will always be a carrier but never suffer from the disease as they eill inherit the healthy wild type allele from the father as one X chromosome comes from the father and the other X chromosome from the mother. The sons will however all suffer from the disease as they inherit the Y chromosome from the father and the X chromosome having the recessive allele causing the disease will be inherited from the mother. Now suppose the mother is a carrier i.e. carries the recessive allele only on one X chromosome but the father suffers from the disease making his genotype XrY (Xr denoting recessive allele carrying X chromosome), then, 50%of their son will duffer from the disease while 50% of the daughters will also have a chance of suffering from the disease. If both the parents do not have a single recessive X linked disease gene on any of their X chromosome then none of the children will suffer from the disease. About phenotype of parents- If the mother is a carrier i.e. have the diseased allele on only one X Chromosome, then the phenotype of mother will be normal. But the father can never be a carrier for a X linked recessive disease as males have only one X chromosome. If the diseased allele in present on that X chromosome in males it will be expressed as there is no dominant healthy wild type allele to dominate the diseased gene. Thus if the father has the recessive diseased allele on X chromosome, the father\'s phenotype will be expresding the disease while if the father do not have the allele he will be healthy. On the other hand for the mother to express the disease the recessive allele has to be present on bith her X chromosome. Probability of offsprings showing the trait- If mother is a carrier and father is normal, then 5.

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Please give an explaination fir those quesions! 2 3 4 5 1. Aman with red.geen colour blindness is marned to a girl with normal colwir vision. What is the probaliliny that his childron will be coluur blind? 2. A boy has Dachenne muscular dyatrophy. His malemal uncle had died of museular dystrophy at the age of 21 years. What is the prohatility that this chilfs sibs will be affected? Assignments \#3 rocosive or S -kinked dominant and X -linked recesive inheritance. (Nole that a potigrte may be coempable with muve thas ane type of inheritance.) Assignnents \#4 Examine the pedieree frum a funily with a ernetic disease and anvv the questiens below: a. Does this pedigree isdicate autosonal deuninant, teoessive of set-link type of inheritance? Give reasons for your choice. b. Assuaning that B and b are the normal and mataut alleies respectively what would be the enenotypes of the individuals :II.1, 11 2 and III .3? c. Individual II. 3 requested genctic counselling. What is the probubility that her child woald be affected. Fxplain why. Assignments \#5 Susan's grandfather was deaf, and passed down a hercditary form of deafhess within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant of recessive?? B. Is it carried on an autosome of a sex cluomosome? Why? C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected, and 7 unaffected) In comparing these 11 SNP result, how long a haplotype block would you expect to find around the critical \#ene? How might you deleet it? Assignments \#1 Distinguish between the following genetic terms: A. Gene and allele. B. Homozygous and heterozygous. C. Genotype and phenotype. D. Dominant and recessive. 1. A man with red-green colour blindness is married to a girl with normal colour vision. What is the probability that his children will be colour blind? 2. A boy has Duchenne muscular dystrophy. His maternal uncle had died of muscular dystrophy at the age of 21 years. What is the probability that this child's sibs will be affected? Explain, giving reasons, whether the following pedigrees are compatible with autosomal dominant, autosomal recessive or X -linked dominant and X -linked recessive inheritance. (Note that a pedigree may be compatible with more than one type of inheritance.) a. b. c. a. b. c. Assignments \#4 Examine the pedigree from a family with a genetic disease and ansv the questions below: a. Does this pedigree indicate autosomal dominant, recessive or sex-link type of inheritance? Give reasons for your choice. b. Assuming that B and b are the normal and mutant alleles respectively what would be the genotypes of the individuals: II.I, II.2 and III.3 ? c. Individual II. 3 requested genetic counselling. What is the probability that her child would be affected. Explain why. Susan's grandfather was deaf, and passed down a hereditary form of deafness within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant or recessive? B. I.

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Which of the following triploblastic invertebrates is incorrectly matched with the type of body cavity it possesses? a) Pseudocoelomate - Flatworm b) Coelomate - Annelida c) Acoelomate - Platyhelminthe d) Pseudocoelomate - Nematoda e) Coelomate - Earthworm Solution Answer: a) Pseudocoelomate - Flatworm Reason: Trematodes: Flatworm are coelomates and trematodes are belongs to flatworms & triploblastic with a true body cavity but not a pseudocoelom These are flatworms and living as internal parasites inside the molluscans, some vertebrates. The life cycle involves two hosts as described below..

Which of the following triploblastic invertebrates is incorrectly ma.pdf

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What is the fundamental difference between shell subscript and C programs? Shell scripts must be compiled before execution, but C programs are interpreted \"on the fly\" Shell scripts must have their executable permissions turned on, but C programs do not need this. Shell scripts can be graphical, but C programs cannot be so. Shell script source code is interpreted \"on the fly\". but C programs must be compiled before execution. A value passed to a shell script from the command line is called a(n) variable value $1 argument Solution Q 34 Shell script source code is interpreted on the fly but C programs must be compiled before execution. 35 A value passed to a shell script from the command line Is called argument.

What is the fundamental difference between shell subscript and C prog.pdf

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