Immunoslide - early leukemia diagnostics. Presentation for HSE 13K competition.

1. Andrey Senyut senyut@immunoslide.com
Early leukemia diagnostics
HSE 13K 10-04-2012

2. Leukemia
350 000 new cases
per year
250 000 deaths per year
Leading cause of death among children under 15

3. Problem
Common methods of leukemia diagnostics are
NOT SENSITIVE ENOUGH
ONLY 4% are diagnosed at the stage of
preventive inspection
The disease is detected TOO LATE

4. Immunoslide
Hi accuracy
Affordable price

5. Immunoslide
Abnormal blood cells appear in a person’s blood stream when he has leukemia.
Pathological cells differ from normal ones by:
External appearance Antigens on their surface
(morphology) (immunophenotype)
EXAMPLE EXAMPLE
There must be no cells with
“CD11C-”
antigen (special protein)
on their surface when a person is
healthy.
Pathological cells
Common methods of leukemia diagnostics (blood smear) don’t deliver the data
about cell’s surface antigens.
Immunoslide allows doctor to receive data both on the external
appearance of blood cells and on the surface antigens of blood cells.

6. Immunoslide
gives
10
TIMES
HIGHER
CHANCE
of
finding
leukemia
at
it’s
early
stage
Sensi(ve
Affordable
Blood
cell
An$gen
Y Y Y Y
Immobilized
an$body
CD
4
CD
4
CD
8
CD
8
Immunoslide
Devise
for
early
leukemia
diagnos(cs.

8. Product
Device for an automated Immunoslide
analysis of immunoslide (disposable)
200 000 rubles 300 rubles per test
+
15% margin 73% margin

9. Russian market
revenue in 5 years – 800 mln rubles
GOVERNMENTAL MARKET
PRIVATE MARKET
Overall market volume - 15.5 bln rubles

10. Financial forecast
Thousands of rubles Thousands of rubles
140,000
140000
120,000
120000
CF without bringing in
100,000
CF 100000
investmnets
80,000
80000
60,000
60000
40000
40,000
20000
20,000
half year half year
0
0
1
2
3
4
5
6
7
8
9
1
2
3
4
5
6
7
8
9
-­‐20000
160000
Thousands of rubles -­‐40000
140000
120000
NPV = 41 mln rubles, r = 40%
100000
EBITDA
IRR = 69%
80000
60000
PBP = 3.8 years
40000
Required investments
20000
half year 54 mln rub
0
1
2
3
4
5
6
7
8
9
-­‐20000

11. Конкурентные методы
Immuno Flow
Immunocit Blood
Slide
cytometry
ochemistry
smear
Morphological
analysis
++
-­‐-­‐
-­‐
+
Immunophenotyping
+
++
+
-­‐-­‐
Cost
of
one
test
350
500
–
1000
600
–
1400
100
rubles
rubles
rubles
rubles
Cost
of
equipment
200
000
3
000
000
-­‐
-­‐
rubles
rubles
Dura(on
of
analysis
1,5
hour
0,5
hour
3
hours
0,5
hour
Simplicity
of
exploita(on
+
-­‐-­‐
-­‐-­‐
+

12. Partners
Governmental clinical and diagnostic laboratories
Morozov children’s hospital Hematological science center
D. Rogachev’s children’s hematological center
Private clinical and diagnostic laboratories

13. – winner of the grant START 2012

14. We are Skolkovo residents

15. Thank you for your attention!
Q&A?
mail@immunoslide.com