1. Recursos Tecnológicos e Formação
Base de dados : MEDLINE_1997-2009
Pesquisa : demencia AND idosos
Operador: And
Descritores: Demencia
Qualificação: Terceira Idade
[PMID]: 19255410
[Au] Autor: Berlau DJ; Corrada MM; Head E; Kawas CH
[Ad] Endereço: Institute of Brain Aging and Dementia, University of California Irvine, Irvine, CA
92697-1400, USA. danb@uci.edu
[Ti] Título: APOE epsilon2 is associated with intact cognition but increased Alzheimer pathology in
the oldest old.
[So] Source: Neurology;72(9):829-34, 2009 Mar 3.
[Is] ISSN: 1526-632X
[Cp] País de United States
publicação:
[La] Idioma: eng
[Ab] Resumo: BACKGROUND: Many studies have examined the role of APOE genotype in the
development of dementia, specifically Alzheimer disease (AD). The APOE epsilon4
allele (APOE4) is a risk factor for both clinical and neuropathologic AD whereas the
APOE epsilon2 allele (APOE2) seems to be protective. This would predict, even with
advanced age, that APOE2 carriers would be less likely to have dementia and less
likely to meet pathologic criteria for AD. METHODS: The first 85 genotyped participants
from The 90+ Study to come to autopsy were included. All-cause dementia (using
DSM-IV criteria) and AD (using National Institute of Neurological and Communicative
Disorders and Stroke-Alzheimer's Disease and Related Disorders Association criteria)
diagnoses were made by consensus conference using all available information
including neuropsychological testing, neurologic examination, and medical records.
Neuropathologic examination included Braak and Braak staging for plaques and
tangles and diagnosis of neuropathologic AD using National Institute on Aging-Reagan
criteria. RESULTS: Across all genotypes, 58.5% of subjects were diagnosed with
clinical dementia (81% of dementia was AD) and 50.0% met neuropathologic criteria
for AD. Compared to those with an APOE epsilon3/epsilon3 genotype (APOE3/3),
APOE4 carriers were more likely to be diagnosed with dementia (odds ratio [OR] =
12.2, 95% confidence interval [CI] = 1.5-102.0), whereas APOE2 carriers were not (OR
= 0.3, 95% CI = 0.1-1.3). Surprisingly, both APOE4 (OR = 4.6, 95% CI = 1.3-16.5) and
APOE2 (OR = 7.8, 95% CI = 1.5-40.2) carriers were more likely to meet
neuropathologic criteria for AD than those with APOE3/3 genotype. CONCLUSIONS: In
the oldest old, the presence of the APOE epsilon2 allele (APOE2) was associated with
a somewhat reduced risk of dementia, but paradoxically was associated with increased
Alzheimer disease (AD) neuropathology. Therefore, oldest old APOE2 carriers may
have some mechanism that contributes to the maintenance of cognition independently
of the formation of AD pathology.
[Pt] Tipo de COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H.,
publicação:
EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de 0 (Apolipoprotein E2)
substância:
[Em] Mês de 0903
entrada:
[Sb] Subgrupo de AIM; IM
revista:
[Da] Data de 090303
entrada para
processamento:
[St] Status: MEDLINE
Ana Gomes e Letícia Silva

2. Recursos Tecnológicos e Formação
[PMID]: 19273804
Base de dados : MEDLINE_1997-2009
[Au] Autor: Nangia V; Bhojwani K; Matin A; Sinha A; Jonas JB AND Idade
Pesquisa : Envelhecimento AND Terceira
[Ti] Título: Intraocular pressure and arterial blood pressure: the Central India Eye and Medical
Operador: Study. And
Descritores: Envelhecimento
Qualificação: Arch Ophthalmol;127(3):339-40, 2009 Mar.
o[So] Source: Terceira Idade
[Is] ISSN: 1538-3601
[Cp] País de United States
publicação:
[La] Idioma: eng
[Pt] Tipo de LETTER; RESEARCH SUPPORT, NON-U.S. GOV'T
publicação:
[Em] Mês de 0903
entrada:
[Sb] Subgrupo de AIM; IM
revista:
[Da] Data de 090310
entrada para
processamento:
[St] Status: MEDLINE
Base de Dados: MEDLINE_1997-2009
Pesquisa: saude AND doenca AND (terceira AND idade)
Operador: And
Descritores: Saúde e Doença
Qualificação: Terceira Idade
Ana Gomes e Letícia Silva

3. Recursos Tecnológicos e Formação
[PMID]: 9761616
[Au] Autor: Carvalho F; Telarolli Junior R; Machado JCMS
[Ad] Endereço: Faculdade de Ciências e Letras de São José do Rio Pardo, Av. Mário
Ybarra de Almeida 1498, Araraquara, SP, 14800-420, Brasil.
[Ti] Título: [An anthropological investigation of old age and concepts concerning
arterial hypertension]
[Ti] Título: Uma investigação antropológica na terceira idade: concepçoes sobre
a hipertensão arterial..
[So] Source: Cad Saude Publica;14(3):617-21, 1998 Jul-Sep.
[Is] ISSN: 0102-311X
[Cp] País de publicação: BRAZIL
[La] Idioma: por
[Ab] Resumo: Anthropology and sociology are joining epidemiology, clinical
investigation, and pathophysiology in studies on the aging process of
the Brazilian population. The objectives of the present study were: a)
to identify the concepts of the elderly population of the municipality of
Araraquara, São Paulo, Brazil, towards the etiology of arterial
hypertension (AH) and the relevance of the different signs and
symptoms that accompany the disease; b) to improve elderly people's
concepts towards the relevance and utilization of different treatment
categories for AH. Structured interviews were conducted with 29
individuals, the majority aged 60 years or over, who were being
treated for hypertension at the Araraquara municipal gerontology
outpatient clinic in August 1996. Patients were properly informed by
the health team about problems related to AH, as clearly perceived in
the discourse of the elderly. Folkloric concepts pertaining to etiology
also appeared in the interviews and should be taken into
consideration in the implementation of health education activities.
Care provided by an interdisciplinary team was valued by the elderly.
The most frequent complaint was the lack of free distribution of
prescription medication for AH at the clinic.
[Mh] Termos MeSH: Adolescente
Adulto
Fatores Etários
Idoso
Envelhecimento/*PH
Antropologia Física
Brasil
Feminino
Educação em Saúde
Hipertensão/DI/*ET/TH
[Pt] Tipo de publicação: ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Mês de entrada: 9811
[Cu] Atualização por classe: 071115
[Lr] Data última revisão: 071115
[Sb] Subgrupo de revista: IM
Ana Gomes e Letícia Silva

4. Recursos Tecnológicos e Formação
[Da] Data de entrada para 981124
processamento:
[St] Status: MEDLINE
Base de Dados: MEDLINE_1997-2009
Pesquisa: sexualidade AND (terceira AND idade)
Operador: And, ()
Descritores: Sexualidade
Qualificação: Terceira Idade
[PMID]: 18723307
[Au] Autor: Politi MC; Clark MA; Rogers ML; McGarry K; Sciamanna CN
[Ad] Endereço: Warren Alpert Medical School of Brown University/The Miriam Hospital,
Centers for Behavioral and Preventive Medicine, CORO Suite 500, One Hoppin
Street, Providence, RI 02903, USA. mary_politi@brown.edu
[Ti] Título: Patient-provider communication and cancer screening among unmarried
women.
[So] Source: Patient Educ Couns;73(2):251-5, 2008 Nov.
[Is] ISSN: 0738-3991
[Cp] País de Ireland
publicação:
[La] Idioma: eng
[Ab] Resumo: OBJECTIVES: Unmarried women are less likely than married women to
receive recommended cancer screenings. Patient-provider communication is a
consistent predictor of cancer screening among women. The purpose of this
study was to investigate the relationship between patient and provider
communication, barriers to cancer screening, and on-schedule breast and
cervical cancer screening (BCCS) among unmarried women. METHODS: Data
were from the Cancer Screening Project for Women, a 2003-2005 survey
examining cancer screening practices. We computed polytomous logistic
regression models to examine the relationship between communication
(communication about tests, communication about sexual and intimate
relationships), barriers to screening, and on-schedule BCCS among unmarried
women. RESULTS: A total of 630 women were enrolled, and 605 women
completed the baseline questionnaire. Overall, more than 60% reported on-
schedule BCCS. More than half reported that their providers communicated
about BCCS most or all of the time. Fewer than half communicated about
sexual history and intimate relationships. Women who reported that their
providers communicated about screening tests and their sexual and intimate
relationships were more likely to be on-schedule for BCCS. CONCLUSION:
Patient-provider communication about multiple topics may encourage women
to remain on-schedule for their recommended cancer screenings. Longitudinal
research should be conducted to examine whether communication predicts
BCCS, and to examine how patient and provider characteristics may influence
communication in order to promote adherence to screening guidelines for
unmarried women. PRACTICE IMPLICATIONS: Comprehensive
Ana Gomes e Letícia Silva

5. Recursos Tecnológicos e Formação
communication that goes beyond information about screening tests may impact
adherence to cancer screening guidelines.
[Mh] Termos Idoso
MeSH:
Programas de Rastreamento/*UT
Meia-Idade
[Pt] Tipo de JOURNAL ARTICLE
publicação:
[Em] Mês de 0903
entrada:
[Sb] Subgrupo de N
revista:
[Da] Data de 090130
entrada para
processamento:
[St] Status: MEDLINE
Base de Dados: MEDLINE_1997-2009
Pesquisa: Depressão AND (Terceira AND Idade)
Operador: AND, ()
Descritores: Depressão
Qualificação: Terceira Idade
Ana Gomes e Letícia Silva

6. Recursos Tecnológicos e Formação
[PMID]: 19273797
[Au] Autor: Wysong A; Lee PP; Sloan FA
[Ad] Endereço: Duke University School of Medicine, Durham, North Carolina 27708, USA.
[Ti] Título: Longitudinal incidence of adverse outcomes of age-related macular
degeneration.
[So] Source: Arch Ophthalmol;127(3):320-7, 2009 Mar.
[Is] ISSN: 1538-3601
[Cp] País de United States
publicação:
[La] Idioma: eng
[Ab] Resumo: OBJECTIVE: To describe the visual, functional, and general health
complication rates associated with age-related macular degeneration (AMD) in
a nationally representative longitudinal sample of elderly persons. METHODS:
This is a longitudinal retrospective cohort study (January 1, 1994-December 31,
2004) that used Medicare claims data. We identified beneficiaries aged 68
years and older who had newly diagnosed AMD in 1994 (n = 32,702) and age-,
sex-, and race-matched controls who had routine eye surveillance and no
diagnosis of AMD throughout the observational period (n = 32,702). Main
outcome measures included cumulative incidence of vision loss, blindness, hip
fracture, depression, and nursing home placement and prevalence of 16
general health conditions. RESULTS: Elderly individuals with newly diagnosed
AMD had higher rates of blindness, vision loss, depression, hip fracture, and
residence in a nursing home than those without AMD during a 10-year follow-
up period. Individuals with AMD also had a higher prevalence of 11 of 16
general health conditions compared with controls. CONCLUSIONS: Individuals
aged 68 years and older with AMD had higher rates of visual and functional
impairments and had more illness than controls. Our findings demonstrate the
substantial resource commitment of caring for the multifaceted health issues of
persons diagnosed with AMD.
[Mh] Termos Idoso
MeSH:
Idoso de 80 Anos ou mais
Transtorno Depressivo/*EP
Feminino
Pesquisa sobre Serviços de Saúde
[Pt] Tipo de JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
publicação:
[Em] Mês de 0903
entrada:
[Sb] Subgrupo de AIM; IM
revista:
[Da] Data de 090310
entrada para
processamento:
[St] Status: MEDLINE
Ana Gomes e Letícia Silva