Sexy Call Girl Kumbakonam Arshi 💚9058824046💚 Kumbakonam Escort Service
Presentation1.pptx
1. Incidence and mortality
•
Endometrial cancer is the most common invasive gynecologic cancer in U.S.
women, with an estimated 65,950 new cases expected to occur in 2022 and an
estimated 12,550 women expected to die of the disease.[1]
•
Endometrial cancer is primarily a disease of postmenopausal women, with a
mean age at diagnosis of 60 years.[2] Age-adjusted endometrial cancer
incidence in the United States has declined since 1975, with a transient increase
in incidence occurring from 1973 to 1978, which was associated with estrogen
therapy, also known as hormone therapy;[3] there was no associated increase in
mortality. Since the mid-2000s, incidence rates increased by about 1% per year.
Between 2015 and 2019, death rates for endometrial cancer increased by 1%
per year, although rates appear to have stabilized in recent years.[1] Most cases
of endometrial cancer are diagnosed because of symptoms, which are
nonetheless early stage and have high survival rates.
2. Screening of asymptomatic women for endometrial
carcinoma Population screening is not feasible.
However, screening may be justified for high risk
women including:
.A
Those with polycystic ovarian syndrome
.B
Any woman with intact uterus taking unopposed
estrogen therapy
.C
Those taking tamoxifen for treatment breast cancer
.D
Those with a family history of lynch II syndrome
(Hereditary non polyposis colorectal cancer
syndrome).
3. Methods of screening
Endometrial sampling followed by cytological
examinationThis sample could be obtained by:
Pap smear:
not a sensitive tool, and 50 % of women with endometrial
cancer will have normal findings.
5. 2. endometrial tissue biopsy:
using Novack’s curette or Kevorkian curette, followed by histo-
pathological examination
6. 3. Imaging:
Transvaginal ultrasound:
• The normal thickness of the endometrium can be
determined by transvaginal ultrasonography.less
Than 5mm
• The endometrial thickness more than 5 mm in a post-
menopausal woman not on ERT and thickness more
than 8mm in a post-menopausal woman on ERT is
suspicious for presence of endometrial carcinoma.
• If the endometrial thickness is high, diagnostic
endometrial assessment is recommended
8. •
Papaioannou S, Tzafettas J. Anovulation with or without PCO, hyperandrogenaemia and
hyperinsulinaemia as promoters of endometrial and breast cancer. Best Pract Res Clin Obstet
Gynaecol. 2010 Feb;24(1):19-27. [PubMed]
•
Amant F, Moerman P, Neven P, Timmerman D, Van Limbergen E, Vergote I. Endometrial
cancer. Lancet. 2005 Aug 6-12;366(9484):491-
•
505. [PubMed
•
Timmermans A, Opmeer BC, Khan KS, Bachmann LM, Epstein E, Clark TJ, Gupta JK, Bakour SH,
van den Bosch T, van Doorn HC, Cameron ST, Giusa MG, Dessole S, Dijkhuizen FPHLJ, Ter Riet
G, Mol BWJ. Endometrial thickness measurement for detecting endometrial cancer in women
with postmenopausal bleeding: a systematic review and meta-analysis. Obstet Gynecol. 2010
Jul;116(1):160-167. [PubMed]
![Incidence and mortality
•
Endometrial cancer is the most common invasive gynecologic cancer in U.S.
women, with an estimated 65,950 new cases expected to occur in 2022 and an
estimated 12,550 women expected to die of the disease.[1]
•
Endometrial cancer is primarily a disease of postmenopausal women, with a
mean age at diagnosis of 60 years.[2] Age-adjusted endometrial cancer
incidence in the United States has declined since 1975, with a transient increase
in incidence occurring from 1973 to 1978, which was associated with estrogen
therapy, also known as hormone therapy;[3] there was no associated increase in
mortality. Since the mid-2000s, incidence rates increased by about 1% per year.
Between 2015 and 2019, death rates for endometrial cancer increased by 1%
per year, although rates appear to have stabilized in recent years.[1] Most cases
of endometrial cancer are diagnosed because of symptoms, which are
nonetheless early stage and have high survival rates.](https://image.slidesharecdn.com/presentation1-230511185915-3e101d10/85/Presentation1-pptx-1-320.jpg)
