SlideShare a Scribd company logo
1 of 28
1
Wollo University, CMHS,
Department of Pediatrics
and Child health Nursing.
Neonatal Nursing.
NEONATOLOGY
Topics
 Neonatal sepsis.
 Neonatal seizures.
 Neonatal injuries.
2
Neonatal Sepsis:
Definition: Generalized infection in the new-born
 According to the onset:
Early onset : birth—7days.
Late onset : 8--- 28 days.
Nosocomial: 1st.week- discharge.
3
Classification: according to organism
Early Late Nosocomial
GBS typeI,II,III GBSIII Staph.epidermis
E.coli E.coli Staph.aureus
Kelebsilla Liesteria
monocytogenus
Candida a
Liesteria
monocytogenus
Herps simplex Psudomonas
aerginosa
Non typeable
H.influnza
_____________ E.coli
NNS, predisposing factors
 Maternal causes(vertical transmission)
TORCH
PROM
UTI
Colonization(GBS, Herpes)
Complicated delivery, multiple births.
5
NNS, predisposing factors con…
 Foetal causes:
Prematurity/LBW
Male gender
Resuscitation /ETT , UVC , UAC
Hospitalisation, crowding , inadequate infection
control.
VP shunt , indwelling catheter, alteration in skin &
mm.
6
NNS: clinical manifestations
 General:
Fever, hypothermia, not doing well, poor feeding ,
sclerema.
 CNS:
Irritability, lethargy, tremors, seizures, hyporeflexia,
irregular respiration , full fontanel, high pitched cry.
7
NNS: clinical cont.
 CVS:
Pallor, mottling, cold clammy skin, tachycardia,
hypotension, bradycardia.
 Respiratory system:
Apnea, dyspnea, tachypnea, retraction, flaring, grunting,
cyanosis.
8
NNS: clinical cont.
 GIT:
Vomiting, diarrhoea, abdominal distension, hepatomegaly.
 Renal: oliguria.
 Haematology:
Jaundice, pallor, petichiae, purpura, bleeding tendency,
splenomegaly.
9
NNS: Investigations
 CBC, differential.
 CRP
, ESR.
 Cultures: blood, CSF, urine, gastric aspirate, ETT aspirate.
 CXR.
10
NNS: Treatment
1. Ampicillin plus aminoglycoside ( gentamycin, Amikacin).
2. 3rd generation cephalosporin (cefotaxim, ceftazidim).
3. Anti staph (cloxacillin or vancomycin)
NB: duration of therapy is 7-10 days
In meningitis, GBS 14 d/G-ve 21 d.
11
NNS, Prevention
 Aggressive treatment of maternal chorioamnionitis.
 Control of nosocomial infection by hand washing & avoid
overcrowding.
12
NEONATAL SEIZURES
Definition:
Paroxysmal involuntary movement due to disturbance of brain
function.
13
NEONATAL SEIZURES cont.
 Classification:
1. Focal seizures.
2. Multifocal clonic seizures.
3. Tonic seizures.
4. Myoclonic seizures.
5. Subtle seizures “chewing , blinking, nystagmus, paddling,
smacking, fisting”.
14
NEONATAL SEIZURES cont.
 Aetiology:
 Hypoxia. HIE.
 Metabolic disturbances: (hypoglycemia,
hypocalcemia , hypomagnesmia , hypo &
hypernatremia).
 Inborn errors of Metabolism.
 Infections: congenital & acquired.
 Traumatic.
15
NEONATAL SEIZURES cont.
 Aetiology: cont.
 Structural abnormalities.
 Hemorrahge.
 Maternal drugs.
16
NEONATAL SEIZURES cont.
 Investigation:
 Glucose, Ca ,Mg .
 Urea & Electrolytes :Na.
 Lumber puncture : CSF
wbc (bacterial, viral) Rbc’s  Hgb.
 Ammonia level.
17
NEONATAL SEIZURES cont.
 Investigation:
 ABG-acidosis.
 Lactate/ Pyruvate ratio.
 Drug screening.
 Imaging: US, CT, MRI.
 Karyotyping.
 EEG.
18
NEONATAL SEIZURES cont.
 Management:
 Primary cause.
 Anticonvulsants:
Phenobarbitone
Phenytoin
19
NEONATAL SEIZURES cont.
Jitteriness vs. seizures:
1. Simple tremors.
2. Stopped by holding the extremities.
3. Enhanced by sensory stimulation.
20
III Birth Injuries
 Definition:
Injury to the newborn during the birth
process
21
III Birth Injuries
 Risk factors:
1. Macrosomia.
2. Prematurity.
3. CPD.
4. Dystocia.
5. Prolonged labour.
6. Breech.
22
III Birth Injuries
 Cranial injuries:
Cephalohematoma
Subgaleal Hemorrage
Intracranial H.
Subdural H.
23
III Birth Injuries
 Intracranial Hge (IVH).
Risk factors :
1. BW < 1500 gm (90%).
2. Hypoxic Ischemic injury.
3. Pneumothorax.
4. Hypo/hyper tension.
5. Coagulopathy.
6. Thrombocytopenia.
7. Vit. K deficiency.
24
III Birth Injuries
 Intracranial Hge (IVH) cont,
CM
-Clinical presentation.
-Diagnosis :U/S Grade I,II,III,IV.
-Management: I, II Recover
grade III, IV hydrocephalus
------>V-P shunt.
25
III Birth Injuries
Peripheral Nerve Injuries:
- Erb΄s palsy ( C5-6 ).
 Clinically :
loss of abduction, external
rotation , supination , loss of bicep reflex &
abnormal Moro reflex.
 Management: physiotherapy, neurosurgery
26
III Birth Injuries
Fractures.
# Clavicle:
-asymmetrical Moro.
-crepitus .
-discoloration.
-immobilization
27
28

More Related Content

Similar to Sepsis, seizure &amp; birth injuries

Infectious Mononeucleosis .pptx
Infectious Mononeucleosis .pptxInfectious Mononeucleosis .pptx
Infectious Mononeucleosis .pptxzahraalali6
 
DR OLATUNYA NEPHROBLASTOMA & NEUROBLASTOMA LECTURE.pptx
DR OLATUNYA  NEPHROBLASTOMA & NEUROBLASTOMA LECTURE.pptxDR OLATUNYA  NEPHROBLASTOMA & NEUROBLASTOMA LECTURE.pptx
DR OLATUNYA NEPHROBLASTOMA & NEUROBLASTOMA LECTURE.pptxFeniksRetails
 
Ebola virus disease by Aminu Arzet
Ebola virus disease by Aminu ArzetEbola virus disease by Aminu Arzet
Ebola virus disease by Aminu ArzetAminuArzet
 
Leukocytic Disorders.ppt
Leukocytic Disorders.pptLeukocytic Disorders.ppt
Leukocytic Disorders.pptssuserf728aa
 
Chediak higashi syndrome
Chediak higashi syndromeChediak higashi syndrome
Chediak higashi syndromebhabilal
 
Recent advances in neonatal septicemia
Recent advances in neonatal septicemiaRecent advances in neonatal septicemia
Recent advances in neonatal septicemiaHemraj Soni
 
Genomics in Public Health
Genomics in Public HealthGenomics in Public Health
Genomics in Public HealthJennifer Gardy
 
Insufficienza epatica bambini
Insufficienza epatica bambiniInsufficienza epatica bambini
Insufficienza epatica bambiniMerqurio
 
Bacterial infection in Newborns.Neonatal sepsis
Bacterial infection in Newborns.Neonatal sepsisBacterial infection in Newborns.Neonatal sepsis
Bacterial infection in Newborns.Neonatal sepsisEneutron
 
Neonatal infectious diseases jornal 2nd topic
Neonatal infectious diseases jornal 2nd topicNeonatal infectious diseases jornal 2nd topic
Neonatal infectious diseases jornal 2nd topicRobin Thomas
 
What is Niemann-Pick Type C Disease?
What is Niemann-Pick Type C Disease?What is Niemann-Pick Type C Disease?
What is Niemann-Pick Type C Disease?Michael G. Stults
 
Syndromes of severe insulin resistance
Syndromes of severe insulin resistanceSyndromes of severe insulin resistance
Syndromes of severe insulin resistanceamir mahmodzadeh
 

Similar to Sepsis, seizure &amp; birth injuries (20)

Herpes viruses
Herpes viruses Herpes viruses
Herpes viruses
 
Nephroblastoma.ppt
Nephroblastoma.pptNephroblastoma.ppt
Nephroblastoma.ppt
 
Infectious Mononeucleosis .pptx
Infectious Mononeucleosis .pptxInfectious Mononeucleosis .pptx
Infectious Mononeucleosis .pptx
 
DR OLATUNYA NEPHROBLASTOMA & NEUROBLASTOMA LECTURE.pptx
DR OLATUNYA  NEPHROBLASTOMA & NEUROBLASTOMA LECTURE.pptxDR OLATUNYA  NEPHROBLASTOMA & NEUROBLASTOMA LECTURE.pptx
DR OLATUNYA NEPHROBLASTOMA & NEUROBLASTOMA LECTURE.pptx
 
Ebola virus disease by Aminu Arzet
Ebola virus disease by Aminu ArzetEbola virus disease by Aminu Arzet
Ebola virus disease by Aminu Arzet
 
Leukocytic Disorders.ppt
Leukocytic Disorders.pptLeukocytic Disorders.ppt
Leukocytic Disorders.ppt
 
Chediak higashi syndrome
Chediak higashi syndromeChediak higashi syndrome
Chediak higashi syndrome
 
Recent advances in neonatal septicemia
Recent advances in neonatal septicemiaRecent advances in neonatal septicemia
Recent advances in neonatal septicemia
 
Neonatal infections
Neonatal infectionsNeonatal infections
Neonatal infections
 
Genomics in Public Health
Genomics in Public HealthGenomics in Public Health
Genomics in Public Health
 
Insufficienza epatica bambini
Insufficienza epatica bambiniInsufficienza epatica bambini
Insufficienza epatica bambini
 
Bacterial infection in Newborns.Neonatal sepsis
Bacterial infection in Newborns.Neonatal sepsisBacterial infection in Newborns.Neonatal sepsis
Bacterial infection in Newborns.Neonatal sepsis
 
Listeria
ListeriaListeria
Listeria
 
Neonatal infectious diseases jornal 2nd topic
Neonatal infectious diseases jornal 2nd topicNeonatal infectious diseases jornal 2nd topic
Neonatal infectious diseases jornal 2nd topic
 
PMN DISORDERS & PERIODONTAL DISEASES
PMN DISORDERS & PERIODONTAL DISEASESPMN DISORDERS & PERIODONTAL DISEASES
PMN DISORDERS & PERIODONTAL DISEASES
 
What is Niemann-Pick Type C Disease?
What is Niemann-Pick Type C Disease?What is Niemann-Pick Type C Disease?
What is Niemann-Pick Type C Disease?
 
Neonatal infections
Neonatal infectionsNeonatal infections
Neonatal infections
 
Syndromes of severe insulin resistance
Syndromes of severe insulin resistanceSyndromes of severe insulin resistance
Syndromes of severe insulin resistance
 
Neisseria, gonorrhoea, STD, meningitis, meningococci, gonococci, bacterial in...
Neisseria, gonorrhoea, STD, meningitis, meningococci, gonococci, bacterial in...Neisseria, gonorrhoea, STD, meningitis, meningococci, gonococci, bacterial in...
Neisseria, gonorrhoea, STD, meningitis, meningococci, gonococci, bacterial in...
 
ART PREGNANCY COMPLICATIONS
ART PREGNANCY COMPLICATIONSART PREGNANCY COMPLICATIONS
ART PREGNANCY COMPLICATIONS
 

Recently uploaded

VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore EscortsVIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escortsaditipandeya
 
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...chandars293
 
VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋
VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋
VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋TANUJA PANDEY
 
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Bangalore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Bareilly Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service AvailableCall Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service AvailableDipal Arora
 
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...vidya singh
 
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Call Girls Tirupati Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Tirupati Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Tirupati Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Tirupati Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Call Girls Dehradun Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Dehradun Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Dehradun Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Dehradun Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...jageshsingh5554
 
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Call Girls Kochi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Kochi Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Kochi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Kochi Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...narwatsonia7
 
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Lucknow Call girls - 8800925952 - 24x7 service with hotel room
Lucknow Call girls - 8800925952 - 24x7 service with hotel roomLucknow Call girls - 8800925952 - 24x7 service with hotel room
Lucknow Call girls - 8800925952 - 24x7 service with hotel roomdiscovermytutordmt
 
Call Girls Siliguri Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Siliguri Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Siliguri Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Siliguri Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...aartirawatdelhi
 
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...hotbabesbook
 
♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...
♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...
♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...astropune
 

Recently uploaded (20)

VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore EscortsVIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escorts
 
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...
 
VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋
VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋
VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋
 
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Bangalore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Bareilly Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service AvailableCall Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
 
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...
 
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls Tirupati Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Tirupati Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Tirupati Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Tirupati Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls Dehradun Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Dehradun Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Dehradun Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Dehradun Just Call 9907093804 Top Class Call Girl Service Available
 
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
 
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls Kochi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Kochi Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Kochi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Kochi Just Call 9907093804 Top Class Call Girl Service Available
 
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...
 
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
 
Lucknow Call girls - 8800925952 - 24x7 service with hotel room
Lucknow Call girls - 8800925952 - 24x7 service with hotel roomLucknow Call girls - 8800925952 - 24x7 service with hotel room
Lucknow Call girls - 8800925952 - 24x7 service with hotel room
 
Call Girls Siliguri Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Siliguri Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Siliguri Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Siliguri Just Call 9907093804 Top Class Call Girl Service Available
 
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...
 
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
 
♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...
♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...
♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...
 

Sepsis, seizure &amp; birth injuries

  • 1. 1 Wollo University, CMHS, Department of Pediatrics and Child health Nursing. Neonatal Nursing.
  • 2. NEONATOLOGY Topics  Neonatal sepsis.  Neonatal seizures.  Neonatal injuries. 2
  • 3. Neonatal Sepsis: Definition: Generalized infection in the new-born  According to the onset: Early onset : birth—7days. Late onset : 8--- 28 days. Nosocomial: 1st.week- discharge. 3
  • 4. Classification: according to organism Early Late Nosocomial GBS typeI,II,III GBSIII Staph.epidermis E.coli E.coli Staph.aureus Kelebsilla Liesteria monocytogenus Candida a Liesteria monocytogenus Herps simplex Psudomonas aerginosa Non typeable H.influnza _____________ E.coli
  • 5. NNS, predisposing factors  Maternal causes(vertical transmission) TORCH PROM UTI Colonization(GBS, Herpes) Complicated delivery, multiple births. 5
  • 6. NNS, predisposing factors con…  Foetal causes: Prematurity/LBW Male gender Resuscitation /ETT , UVC , UAC Hospitalisation, crowding , inadequate infection control. VP shunt , indwelling catheter, alteration in skin & mm. 6
  • 7. NNS: clinical manifestations  General: Fever, hypothermia, not doing well, poor feeding , sclerema.  CNS: Irritability, lethargy, tremors, seizures, hyporeflexia, irregular respiration , full fontanel, high pitched cry. 7
  • 8. NNS: clinical cont.  CVS: Pallor, mottling, cold clammy skin, tachycardia, hypotension, bradycardia.  Respiratory system: Apnea, dyspnea, tachypnea, retraction, flaring, grunting, cyanosis. 8
  • 9. NNS: clinical cont.  GIT: Vomiting, diarrhoea, abdominal distension, hepatomegaly.  Renal: oliguria.  Haematology: Jaundice, pallor, petichiae, purpura, bleeding tendency, splenomegaly. 9
  • 10. NNS: Investigations  CBC, differential.  CRP , ESR.  Cultures: blood, CSF, urine, gastric aspirate, ETT aspirate.  CXR. 10
  • 11. NNS: Treatment 1. Ampicillin plus aminoglycoside ( gentamycin, Amikacin). 2. 3rd generation cephalosporin (cefotaxim, ceftazidim). 3. Anti staph (cloxacillin or vancomycin) NB: duration of therapy is 7-10 days In meningitis, GBS 14 d/G-ve 21 d. 11
  • 12. NNS, Prevention  Aggressive treatment of maternal chorioamnionitis.  Control of nosocomial infection by hand washing & avoid overcrowding. 12
  • 13. NEONATAL SEIZURES Definition: Paroxysmal involuntary movement due to disturbance of brain function. 13
  • 14. NEONATAL SEIZURES cont.  Classification: 1. Focal seizures. 2. Multifocal clonic seizures. 3. Tonic seizures. 4. Myoclonic seizures. 5. Subtle seizures “chewing , blinking, nystagmus, paddling, smacking, fisting”. 14
  • 15. NEONATAL SEIZURES cont.  Aetiology:  Hypoxia. HIE.  Metabolic disturbances: (hypoglycemia, hypocalcemia , hypomagnesmia , hypo & hypernatremia).  Inborn errors of Metabolism.  Infections: congenital & acquired.  Traumatic. 15
  • 16. NEONATAL SEIZURES cont.  Aetiology: cont.  Structural abnormalities.  Hemorrahge.  Maternal drugs. 16
  • 17. NEONATAL SEIZURES cont.  Investigation:  Glucose, Ca ,Mg .  Urea & Electrolytes :Na.  Lumber puncture : CSF wbc (bacterial, viral) Rbc’s  Hgb.  Ammonia level. 17
  • 18. NEONATAL SEIZURES cont.  Investigation:  ABG-acidosis.  Lactate/ Pyruvate ratio.  Drug screening.  Imaging: US, CT, MRI.  Karyotyping.  EEG. 18
  • 19. NEONATAL SEIZURES cont.  Management:  Primary cause.  Anticonvulsants: Phenobarbitone Phenytoin 19
  • 20. NEONATAL SEIZURES cont. Jitteriness vs. seizures: 1. Simple tremors. 2. Stopped by holding the extremities. 3. Enhanced by sensory stimulation. 20
  • 21. III Birth Injuries  Definition: Injury to the newborn during the birth process 21
  • 22. III Birth Injuries  Risk factors: 1. Macrosomia. 2. Prematurity. 3. CPD. 4. Dystocia. 5. Prolonged labour. 6. Breech. 22
  • 23. III Birth Injuries  Cranial injuries: Cephalohematoma Subgaleal Hemorrage Intracranial H. Subdural H. 23
  • 24. III Birth Injuries  Intracranial Hge (IVH). Risk factors : 1. BW < 1500 gm (90%). 2. Hypoxic Ischemic injury. 3. Pneumothorax. 4. Hypo/hyper tension. 5. Coagulopathy. 6. Thrombocytopenia. 7. Vit. K deficiency. 24
  • 25. III Birth Injuries  Intracranial Hge (IVH) cont, CM -Clinical presentation. -Diagnosis :U/S Grade I,II,III,IV. -Management: I, II Recover grade III, IV hydrocephalus ------>V-P shunt. 25
  • 26. III Birth Injuries Peripheral Nerve Injuries: - Erb΄s palsy ( C5-6 ).  Clinically : loss of abduction, external rotation , supination , loss of bicep reflex & abnormal Moro reflex.  Management: physiotherapy, neurosurgery 26
  • 27. III Birth Injuries Fractures. # Clavicle: -asymmetrical Moro. -crepitus . -discoloration. -immobilization 27
  • 28. 28