13. ❂ Which drug is an estrogen receptor antagonist?
1) Chlorpromazine
2) Propranolol
3) Tamoxifen
4) Naloxone
14. ❂Which drug is responsible for blocking the renal tubule
Na+ channel?
1) Amiloride
2) Tetrodotoxin
3) Local anaesthetics
4) Divalent cations(cd+2)
15. ❂ Which substance is a dopamine (D2) receptor agonist?
1) Ethinylestradil
2) Bromocriptine
3) Isoprenaline
4) Vareniciline
16. ❂ Which drug inhibits thymidine kinase enzyme?
1) Saquinavir
2) Sildenafil
3) Aciclovir
4) Captopril
17. ❂ Which drug is responsible for producing neutropenia
and agranulocytosis?
1) Thioureylenes
2) Levothythyroxine
3) Liothyronine
4) Radioiodine
18. ❂ The drug entacapone acts on the
___________________ enzyme.
1) Monoamine oxidase (MAO-B)
2) Dopamine hydroxylase
3) DDC (dopamine decarboxylase)
4) COMT(catechol ortho-methyl transferase)
19. ❂ Which drug increases guanyl cyclase activity?
1) Epoprostenol
2) Glyceryl trinitrate
3) B2-adrenoceptor
4) Adenosine
20. ❂ The following drugs are directly acting vasodilators
except one :
1) Nifedipine
2) Diltiazem
3) Ramipril
4) Verapamil
21. ❂ Which drug is a renin inhibitor?
1) Losartan
2) Ramipril
3) Hydralazine
4) Aliskiren
22. ❂ Which antihypertensive drug class possess highest
postural hypotension side effect?
1) Thiazide diuretics
2) ACE inhibitors
3) Alpha1-adrenoceptor antagonists
4) B-adrenoceptor antagonists
23. ❂ Which antihypertensive drug class has the highest
level of impotence side effects?
1) ACE (Angiotensin-converting-enzyme) inhibitors
2) Thiazide diuretics
3) AT1 (angiotensin II type 1 receptor) antagonists
4) B-adrenoceptor antagonist
24. ❂ The normal systolic pulmonary pressure range in
adults is _________________.
1) 5 mmHg
2) 15 mmHg
3) 10 mmHg
4) 20 mmHg
25. ❂ Which medicine is used in Raynaud's disease?
1) Carvedilol
2) Bisoprolol
3) Nifedipine
4) Bosentan
26. ❂ Which lipoprotein contains the apoB-100 protein?
1) LDL particle
2) HDL particle
3) VLDL particle
4) Chylomicrons
27. ❂ Which lipoprotein contains the apoB-48 protein?
1) HDL particle
2) VLDL particle
3) LDL particle
4) Chylomicrons
28. ❂ What is the particle size of HDL (high density
lipoprotein ) ?
1) 7-20 nm
2) 20-30 nm
3) 30-80 nm
4) 100-1000 nm
29. ❂ Which condition is a risk factor for atheromatous
disease?
1) Raised low density cholesterol
2) Raised high density cholesterol
3) Reduced high density cholesterol
4) Diabetes mellitus
5) More than one option
31. ❂ Nicotinic acid acts on which receptor to produce its
lipid-lowering property?
1) HM73A
2) HM74A
3) HM71A
4) HM72A
32. ❂ The following antimetabolite drugs act on the purine
pathway except one:
1) Fludarabine
2) Cladibrime
3) Tegafur
4) Nelarbime
33. ❂ Which drug is used in the treatment of germ cell
tumors?
1) Lomistine
2) Cisplatin
3) Cyclophosphamide
4) Busulfan
34. ❂ Which cytotoxic drug is used as an antiemetic agent?
1) Nabilone
2) Tamoxifen
3) Etoposide
4) Paclituxel
35. ❂ MODY (maturity onset diabetes of the Youth) is part of
which type of diabetes?
1) TYPE-2 diabetes
2) TYPE-1 diabetes
3) Gestational diabetes
4) Diabetes insipidus
36. ❂ Which drug has mixed agonist-antagonist (K agonist and mu
receptor antagonist or weak partial agonist) property?
1) Etorphine
2) Codeine
3) Nalorphine
4) Dextropropoxyphene
37. ❂ Which opioid analgesic is primarily used in postoperative
pain?
1) Codeine
2) Tramadol
3) Dextropropoxyphene
4) Remifentanil
38. ❂ Which is a long acting opioid antagonist?
1) Naltrexone
2) Naloxone
3) Pentazocine
4) Alvimopan
39. ❂ The following are typical antipsychotic drugs except
one:
1) Promazine
2) Chlorpromazine
3) Haloperidol
4) Clozapine
40. ❂ Which antipsychotic drug causes agramocytosis?
1) Amisulpride
2) Flupentixol
3) Clozapine
4) Decanoate
41. ❂ Which drug is responsible for producing jaundice?
1) Chlorpromazine
2) Clozapine
3) Olanzapine
4) Flupentixol
42. ❂ Which medicine is used in the prevention of
migraine?
1) Somatriptan
2) Fluoxetine
3) Ondansetron
4) Pizotifen
43. ❂ Which medicine is used for the treatment supraventricular
tachycardia?
1) Atropine
2) Adrenaline
3) Adenosine
4) Digoxin
44. ❂ Which medicine is used for anxiety?
1) Buspirone
2) Somatriptan
3) Ondansetron
4) Fluoxetine
45. ❂ Which medicine is used for depression?
1) Pizotifen
2) Buspirone
3) Fluoxetine
4) Somatriptan