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Zoom (reduced field of view) Magnetic Resonance Spectroscopic Imaging MRSI

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Uzay Emir
Uzay Emir

A zoom or reduced-field of view (rFOV) metabolite-cycled full-intensity magnetic resonance spectroscopic imaging (MRSI) at 3T with a nominal resolution of 62.5 μL was developed. Single-slice rFOV MRSI data were acquired from the cerebellum of 5 healthy subjects with a nominal resolution of 2.5 × 2.5 mm2 in 9 minutes 36. Spectra were quantified with LCModel. A spatially unbiased atlas template of the cerebellum was used for analyzing metabolite distributions in the cerebellum.

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Cerebellum Metabolic Imaging Uzay E Emir uemir@purdue.edu
Creatine Distribution
NAA Distribution
Myo-Inositol
Glutamate Distribution
Choline Distribution
Right Crus I – Left-Right Dentate Ins Cho Cr NAA Glx Mean Difference -0.06188 -0.01568 0.049662 -0.04693 0.061623 T Value 3.073532 4.038949 4.658737 2.695809 3.438078 P-Values 0.015266 0.003741 0.001626 0.02725 0.008849
Left Crus I – Left-Right Dentate Ins Cho Cr NAA Glx Mean Difference -0.04661 -0.01276 0.057897 -0.05547 0.050548 T Value 2.281465 3.204354 3.696804 3.21391 2.301106 P-Values 0.051952 0.01253 0.00607 0.012352 0.050384

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