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Evolving the Regional Innovation Cluster Paradigm 
for an Innovation Driven Economy 
Scott Dempwolf 
Academic 3: The Evolution of Cluster: from the Competitive Advantage 
of Nations to the Cluster Initiatives Greenbook 2.0 
12 November 2014
Network Models of Regional 
Innovation Clusters and their 
Influence on Economic Growth 
Evolving the Regional Innovation Cluster Paradigm 
for an Innovation Driven Economy 
17th TCI Global Conference 
Monterrey Mexico 
November 12, 2014 
C. Scott Dempwolf, PhD 
Assistant Research Professor 
& Director 
UMD – Morgan State Joint 
Center for Economic Development
Regional Innovation Clusters (RIC) 
“A geographically-bounded, active network of similar, synergistic or complementary 
organizations in a sector or industry that leverages the region’s unique competitive 
strengths to create jobs and broaden prosperity.” (EDA, 2011) 
This research… 
• Validates current cluster 
theory and policies 
• Exposes their limitation 
• Offers useful extensions 
We have an opportunity to take 
Regional Innovation Clusters to 
the next level – to respond to 
innovation-driven growth 
Limits of Cluster Analysis 
1. Active networks are not geographically 
bounded 
2. presence of networks is assumed but 
not measured 
3. NAICS-based clusters not sensitive to 
emergence 
4. based on employment data; does not 
connect economic growth to innovation 
5. Backward-looking
Innovation Driven Growth 
a simple stylized model 
Invention 
Basic Research 
Production 
Development 
Product Improvement 
Research Parks 
Incubators 
Production Employment 
Business Attraction 
Business Expansion 
Business Retention 
Innovation 
based 
Production 
TBED 
Response 
years
Innovation Driven Growth 
how do we measure it now? 
Invention 
Basic Research 
Production 
Development 
Product Improvement 
Research Parks 
Incubators 
Production Employment 
First Employment Data Available 
Clusters defined by established 
Industries, not emerging technologies 
Business Attraction 
Business Expansion 
Business Retention 
~ 5 years +/- 
Innovation 
based 
Production 
Regional 
Cluster 
Analysis 
years 
Bottom Line 
Industry clusters -by whatever name- reflect 
the state of innovation about five years ago
Innovation Driven Growth 
gaining early actionable intelligence 
Invention 
Basic Research 
Production 
Development 
Product Improvement 
Production Employment 
First Employment Data Available 
This approach can shorten 
the lag between real-time 
innovation and actionable 
economic development 
intelligence by several years 
while also revealing rich 
talent pools, emerging 
technology trends, and 
specific E.D. targets 
Clusters defined by established 
Industries, not emerging technologies 
Research Parks 
Patents 
SBIR Awards 
NIH Awards 
NSF Awards 
NASA Awards 
~ 5 years +/- 
Innovation 
based 
Production 
A New 
Approach 
Available Data Sets 
Innovation 
Network Analysis 
years 
~ 4 years +/- 
State Investment Data 
Incubators 
Business Attraction 
Business Expansion 
Business Retention
Networks & Network Models 
Georgia Innovation Network 2008 – 2010 
Locations of selected actors 
Networks made up of nodes (vertices) 
and links (ties, edges) 
Nodes are actors, agents or objects 
People, Organizations, Agencies, 
Documents, Places * 
Links are the relationships that 
connect the nodes 
Regional innovation clusters are 
geographically concentrated but also 
have important ties to distant actors
Analyzing Regional Innovation Networks 
Extract relationships from patent and 
research grant data - about 7M records 
Use social network analysis (SNA) to 
analyze and visualize network structure 
Theoretical grounding in sociology 
and science of complexity 
Behavior of the core network guides 
behavior of whole network 
Clustering based on intensity of 
relationships 
This reveals emerging technologies - what 
people and firms are working on – and 
specialized talent pools 
Battelle Innovation Network 2005 – 2010 
Created with NodeXL
1. Innovation is more global and more 
interconnected than previously 
thought 
2. Network structure influences 
manufacturing employment growth 
within about 3 years of patent 
application (more for med & 
pharma) 
3. Economic development strategies 
that enhance innovation networks 
may be a cost-effective alternative 
to current capital intensive 
strategies. 
4. Innovation networks are (or could be) 
drivers of economic development in 
tier 2 manufacturing regions. 
PA Innovation Clusters 
Westinghouse 
Westinghouse cluster, Pittsburgh PA Dissertation Conclusions 
Network graphics created with NodeXL 
Allegheny County 
Westmoreland County 
Core 
2nd tier 
3rd tier
Regional Innovation Clusters 
are Complex, Emergent Systems 
Networks are Ideal for Modeling Complex Systems: 
• involve many interconnected or interacting parts 
• exhibit emergence - behaviors that cannot be understood or 
predicted by looking at the components of the system alone 
• Emergence is characteristic 
of self-organizing networks 
• The behavior of the whole 
network is driven by the 
behavior of the core 
• Thus we can focus on the 
core and filter out the noise 
Pennsylvania Innovation Networks 1990 - 2007 in the periphery
Applications 
1. Illinois Battery Cluster (2014) 
 Identifying emerging opportunities 
 Combining cluster and network analysis to develop targeted strategies 
2. Great Lakes Patent network (2011) 
 Finding current opportunity for growth in large active clusters 
 Identifying talent pools 
3. Georgia Tech Research Network (2013) 
 Visualizing & managing the research portfolio 
 Identifying University collaborations 
4. Maryland Innovation Network (2011) 
 Biotech & Pharma – differentiating comingled clusters 
 Zooming in to look at Baltimore’s Clusters 
5. Startups, Venture Capital & Accelerators (2014) 
 The CrunchBase network for Maryland 
 The CrunchBase network for Illinois 
6. New Jersey Solar –PV Research & Manufacturing network (2012) 
 Visualizing the university – industry gap 
 Developing a targeted strategy
Illinois Battery Cluster 
The Illinois Battery Cluster 
illustrates how network analysis 
can augment industry cluster 
analysis by identifying emerging 
technologies and opportunities 
for innovation – led growth. 
Using network and cluster 
analysis together economic 
developers can rapidly develop 
detailed strategies, identifying 
the specific firms, institutions 
and agencies involved and how 
they need to connect to achieve 
economic growth.
Illinois Battery Cluster 
Cluster Analysis 
• Battery manufacturing split 
between two clusters 
• Communications (335912: 1 
est; empl N/A for 2012) 
• Lighting (335911: 11 est; empl 
N/A for 2012) 
• NAICS 33591 Battery manufacturing 
2013 (BLS) 
– 2013 Location Quotient = .34 
– 18 establishments 
– 565 employees 
Communications Cluster 
Communications Equipment Components sub-cluster 
Lighting Cluster 
Storage Batteries sub-cluster 
Conclusion: Limited opportunity
Illinois Battery Cluster
Illinois Battery Cluster
Illinois Battery Cluster 
Network Analysis 
• 2012 - $120M JCESR created at Argonne 
• ‘5-5-5’ goal  significant industry growth ~ 
2017 
• Network identifies specific firms + real & 
potential research ties in specific 
technologies 
Conclusion: The combination of limited 
production capacity (from cluster analysis), 
strong research capacity & research investment 
suggest specific economic development 
strategies to capture future job growth. 
• Build industry partnerships around existing 
firms & supply chains to facilitate growth 
• Target specific firms for attraction to grow 
cluster rapidly
Great Lakes Regional Innovation & 
Manufacturing Clusters (core)
Great Lakes Innovation Clusters Impact 
on Planning Practice
Potential University Applications 
Well suited for integrating and 
managing research across 
multiple institutions via open 
networks rather than institutional 
structure 
Visualizing a Research Portfolio 
Offers both a big picture and 
details of technology 
commercialization areas and 
opportunities Georgia Tech Innovation Network 2008 - 2010 (2 steps) 
Created with NodeXL
Maryland Innovation Clusters 2008 - 2010 
This analysis showed that the 
clustering algorithm is sensitive 
enough to distinguish between 
pharma and biotech. 
Maryland Innovation Network 2008 – 2010 
Created with NodeXL 
Baltimore Innovation Network 2008 – 2010 
Created with NodeXL
CrunchBase startup networks 2005-2014 
Illinois Startup Network 
Although similar in size the Illinois 
network exhibits more robust 
structure 
Little discernable structure; clustering 
appears weak 
Maryland Startup Network 
Some structure and beginnings of 
clusters apparent
Maryland 
Startup Network (CrunchBase 2005 - 2014) 
When clustered, spatial agglomeration is the main organizing factor both 
locally and for distant capital sources; DBED & TEDCO feature 
prominently, followed by a few investment firms.
Maryland 
Startup Network (CrunchBase 2005 - 2014) 
Removing New York, Boston and San Francisco nodes diminishes 
spatial influence as an organizing influence, allowing technology clusters 
to emerge. (between-cluster ties hidden in this graph)
Illinois 
Startup Network (CrunchBase 2005 - 2014) 
Spatial agglomeration is an important factor in Chicago and North Shore 
clusters; Excelerate Labs & HealthBox are prominent accelerators 
locally; Strong ‘portfolio’ organization in remaining clusters
New Jersey Solar PV Cluster 2008 - 2010 
Fruchterman-Reingold layout 
In NodeXL 
This analysis revealed significant 
gaps between solar PV research 
& development and solar PV 
component manufacturing. 
Grid layout in NodeXL 
Production Core 
Research 
Core
Next Steps 
Academic Research 
• Publications 
• Presentations at SSTI, TCI Global 
• Complete County-level application – St. Mary’s 
County, MD CEDS 
• Seek NSF SciSIP funding for additional network 
research; validation & calibration of the 
economic model 
• Pending proposal with NIST to evaluate their 
impact on innovation and commercialization 
(alternative metrics to patent counts) 
• Collaboration with UMD HCIL on improvements 
to visualizations and NodeXL software 
Commercialization 
• Launch startup company (fall 2014) 
• Engage ten pilot communities / regions over the 
next two years 
– Mix of different sizes, scales, level of organization, 
density 
– Focus primarily on manufacturing regions 
– Some with cluster strategies, some without 
• Pilot studies may include 
– A network report (limited version of Illinois 
Roadmap) 
– Traditional cluster analysis using the Harvard tool 
for regions that don’t have it 
– An interactive network model 
– On-site training & Technical Assistance 
• Evaluation of performance across all pilot 
regions

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Evolving Regional Innovation Clusters for an Innovation Driven Economy

  • 1. Evolving the Regional Innovation Cluster Paradigm for an Innovation Driven Economy Scott Dempwolf Academic 3: The Evolution of Cluster: from the Competitive Advantage of Nations to the Cluster Initiatives Greenbook 2.0 12 November 2014
  • 2. Network Models of Regional Innovation Clusters and their Influence on Economic Growth Evolving the Regional Innovation Cluster Paradigm for an Innovation Driven Economy 17th TCI Global Conference Monterrey Mexico November 12, 2014 C. Scott Dempwolf, PhD Assistant Research Professor & Director UMD – Morgan State Joint Center for Economic Development
  • 3. Regional Innovation Clusters (RIC) “A geographically-bounded, active network of similar, synergistic or complementary organizations in a sector or industry that leverages the region’s unique competitive strengths to create jobs and broaden prosperity.” (EDA, 2011) This research… • Validates current cluster theory and policies • Exposes their limitation • Offers useful extensions We have an opportunity to take Regional Innovation Clusters to the next level – to respond to innovation-driven growth Limits of Cluster Analysis 1. Active networks are not geographically bounded 2. presence of networks is assumed but not measured 3. NAICS-based clusters not sensitive to emergence 4. based on employment data; does not connect economic growth to innovation 5. Backward-looking
  • 4. Innovation Driven Growth a simple stylized model Invention Basic Research Production Development Product Improvement Research Parks Incubators Production Employment Business Attraction Business Expansion Business Retention Innovation based Production TBED Response years
  • 5. Innovation Driven Growth how do we measure it now? Invention Basic Research Production Development Product Improvement Research Parks Incubators Production Employment First Employment Data Available Clusters defined by established Industries, not emerging technologies Business Attraction Business Expansion Business Retention ~ 5 years +/- Innovation based Production Regional Cluster Analysis years Bottom Line Industry clusters -by whatever name- reflect the state of innovation about five years ago
  • 6. Innovation Driven Growth gaining early actionable intelligence Invention Basic Research Production Development Product Improvement Production Employment First Employment Data Available This approach can shorten the lag between real-time innovation and actionable economic development intelligence by several years while also revealing rich talent pools, emerging technology trends, and specific E.D. targets Clusters defined by established Industries, not emerging technologies Research Parks Patents SBIR Awards NIH Awards NSF Awards NASA Awards ~ 5 years +/- Innovation based Production A New Approach Available Data Sets Innovation Network Analysis years ~ 4 years +/- State Investment Data Incubators Business Attraction Business Expansion Business Retention
  • 7. Networks & Network Models Georgia Innovation Network 2008 – 2010 Locations of selected actors Networks made up of nodes (vertices) and links (ties, edges) Nodes are actors, agents or objects People, Organizations, Agencies, Documents, Places * Links are the relationships that connect the nodes Regional innovation clusters are geographically concentrated but also have important ties to distant actors
  • 8. Analyzing Regional Innovation Networks Extract relationships from patent and research grant data - about 7M records Use social network analysis (SNA) to analyze and visualize network structure Theoretical grounding in sociology and science of complexity Behavior of the core network guides behavior of whole network Clustering based on intensity of relationships This reveals emerging technologies - what people and firms are working on – and specialized talent pools Battelle Innovation Network 2005 – 2010 Created with NodeXL
  • 9. 1. Innovation is more global and more interconnected than previously thought 2. Network structure influences manufacturing employment growth within about 3 years of patent application (more for med & pharma) 3. Economic development strategies that enhance innovation networks may be a cost-effective alternative to current capital intensive strategies. 4. Innovation networks are (or could be) drivers of economic development in tier 2 manufacturing regions. PA Innovation Clusters Westinghouse Westinghouse cluster, Pittsburgh PA Dissertation Conclusions Network graphics created with NodeXL Allegheny County Westmoreland County Core 2nd tier 3rd tier
  • 10. Regional Innovation Clusters are Complex, Emergent Systems Networks are Ideal for Modeling Complex Systems: • involve many interconnected or interacting parts • exhibit emergence - behaviors that cannot be understood or predicted by looking at the components of the system alone • Emergence is characteristic of self-organizing networks • The behavior of the whole network is driven by the behavior of the core • Thus we can focus on the core and filter out the noise Pennsylvania Innovation Networks 1990 - 2007 in the periphery
  • 11. Applications 1. Illinois Battery Cluster (2014)  Identifying emerging opportunities  Combining cluster and network analysis to develop targeted strategies 2. Great Lakes Patent network (2011)  Finding current opportunity for growth in large active clusters  Identifying talent pools 3. Georgia Tech Research Network (2013)  Visualizing & managing the research portfolio  Identifying University collaborations 4. Maryland Innovation Network (2011)  Biotech & Pharma – differentiating comingled clusters  Zooming in to look at Baltimore’s Clusters 5. Startups, Venture Capital & Accelerators (2014)  The CrunchBase network for Maryland  The CrunchBase network for Illinois 6. New Jersey Solar –PV Research & Manufacturing network (2012)  Visualizing the university – industry gap  Developing a targeted strategy
  • 12. Illinois Battery Cluster The Illinois Battery Cluster illustrates how network analysis can augment industry cluster analysis by identifying emerging technologies and opportunities for innovation – led growth. Using network and cluster analysis together economic developers can rapidly develop detailed strategies, identifying the specific firms, institutions and agencies involved and how they need to connect to achieve economic growth.
  • 13. Illinois Battery Cluster Cluster Analysis • Battery manufacturing split between two clusters • Communications (335912: 1 est; empl N/A for 2012) • Lighting (335911: 11 est; empl N/A for 2012) • NAICS 33591 Battery manufacturing 2013 (BLS) – 2013 Location Quotient = .34 – 18 establishments – 565 employees Communications Cluster Communications Equipment Components sub-cluster Lighting Cluster Storage Batteries sub-cluster Conclusion: Limited opportunity
  • 16. Illinois Battery Cluster Network Analysis • 2012 - $120M JCESR created at Argonne • ‘5-5-5’ goal  significant industry growth ~ 2017 • Network identifies specific firms + real & potential research ties in specific technologies Conclusion: The combination of limited production capacity (from cluster analysis), strong research capacity & research investment suggest specific economic development strategies to capture future job growth. • Build industry partnerships around existing firms & supply chains to facilitate growth • Target specific firms for attraction to grow cluster rapidly
  • 17. Great Lakes Regional Innovation & Manufacturing Clusters (core)
  • 18. Great Lakes Innovation Clusters Impact on Planning Practice
  • 19. Potential University Applications Well suited for integrating and managing research across multiple institutions via open networks rather than institutional structure Visualizing a Research Portfolio Offers both a big picture and details of technology commercialization areas and opportunities Georgia Tech Innovation Network 2008 - 2010 (2 steps) Created with NodeXL
  • 20. Maryland Innovation Clusters 2008 - 2010 This analysis showed that the clustering algorithm is sensitive enough to distinguish between pharma and biotech. Maryland Innovation Network 2008 – 2010 Created with NodeXL Baltimore Innovation Network 2008 – 2010 Created with NodeXL
  • 21. CrunchBase startup networks 2005-2014 Illinois Startup Network Although similar in size the Illinois network exhibits more robust structure Little discernable structure; clustering appears weak Maryland Startup Network Some structure and beginnings of clusters apparent
  • 22. Maryland Startup Network (CrunchBase 2005 - 2014) When clustered, spatial agglomeration is the main organizing factor both locally and for distant capital sources; DBED & TEDCO feature prominently, followed by a few investment firms.
  • 23. Maryland Startup Network (CrunchBase 2005 - 2014) Removing New York, Boston and San Francisco nodes diminishes spatial influence as an organizing influence, allowing technology clusters to emerge. (between-cluster ties hidden in this graph)
  • 24. Illinois Startup Network (CrunchBase 2005 - 2014) Spatial agglomeration is an important factor in Chicago and North Shore clusters; Excelerate Labs & HealthBox are prominent accelerators locally; Strong ‘portfolio’ organization in remaining clusters
  • 25. New Jersey Solar PV Cluster 2008 - 2010 Fruchterman-Reingold layout In NodeXL This analysis revealed significant gaps between solar PV research & development and solar PV component manufacturing. Grid layout in NodeXL Production Core Research Core
  • 26. Next Steps Academic Research • Publications • Presentations at SSTI, TCI Global • Complete County-level application – St. Mary’s County, MD CEDS • Seek NSF SciSIP funding for additional network research; validation & calibration of the economic model • Pending proposal with NIST to evaluate their impact on innovation and commercialization (alternative metrics to patent counts) • Collaboration with UMD HCIL on improvements to visualizations and NodeXL software Commercialization • Launch startup company (fall 2014) • Engage ten pilot communities / regions over the next two years – Mix of different sizes, scales, level of organization, density – Focus primarily on manufacturing regions – Some with cluster strategies, some without • Pilot studies may include – A network report (limited version of Illinois Roadmap) – Traditional cluster analysis using the Harvard tool for regions that don’t have it – An interactive network model – On-site training & Technical Assistance • Evaluation of performance across all pilot regions