Background- Marfan syndrome is an autosomal dominant trait that leads.pdf
1. Background: Marfan syndrome is an autosomal dominant trait that leads to weakened connective
tissue in the body. This condition leads to elongated limbs and could affect the heart and vision.
Two patients come to see you about their unborn child. The father has marfan syndrome and the
mother does not. They are concerned that their child will have marfan syndrome especially since
the grandmother on the father's side had marfan syndrome. The mother has no marfan syndrome
in their family. Question: Using your knowledge, explain to the patients what the probability is
that their child will be born with marfan syndrome. (Hint: Draw a pedigree to help)