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Interven'onal	
  
Procedures	
  in	
  Chronic	
  
Pain	
  	
  
	
  
Dr	
  Brendan	
  Moore	
  
Specialist	
  Pain	
  Medicine	
  Physician	
  
Adjunct	
  Associate	
  Professor	
  
	
  University	
  of	
  Queensland	
  
Degenera've	
  Lumbar	
  Back	
  Pain	
  
Origins	
  of	
  lumbar	
  pain	
  
•  Degenera've	
  Discs	
  
•  Vertebral	
  fractures	
  
•  Spinal	
  /	
  Foraminal	
  
Stenosis	
  
•  Disc	
  Bulge	
  /	
  Prolapse	
  
•  Facet	
  Joint	
  	
  
•  Muscle	
  /	
  So@	
  'ssue	
  	
  
Invasive	
  Treatment	
  Op'ons	
  
•  Surgery	
  
•  Facet	
  Joint	
  Injec'on	
  
•  Radiofrequency	
  medial	
  branch	
  abla'on	
  
•  Epidural	
  /	
  Caudal	
  steroid	
  
•  Vertebroplasty	
  
•  Coeliac	
  /	
  Lumbar	
  Sympathe'c	
  Plexus	
  Blocks	
  
•  Sacro-­‐iliac	
  Joint	
  injec'on	
  
Posterior	
  Elements	
  
•  Facet	
  Joints	
  frequently	
  implicated	
  in	
  pain	
  
•  Mechanical	
  back	
  pain	
  with	
  upper	
  leg	
  and	
  buNock	
  
radia'on	
  
Appropriate conditions for
interventional pain procedures
•  Aseptic conditions
•  Monitored sedation
with anaesthetist in
attendance
•  Image intensifying X-
ray or CT guidance
•  Appropriate analgesia
Procedures
•  Epidural injections
–  Cervical, Thoracic, Lumbar, Caudal
•  Facet joint injections
•  Sacroiliac joint injections
•  Medial branch blocks
•  Radiofrequency nerve ablation
Epidural injections
•  Most effective in the presence of nerve root
compression and spinal stenosis
•  Increased efficacy if given in the first weeks of
the onset of pain
•  Effects of the injection tend to be temporary (1
week to 1 year)
•  Can be beneficial in providing relief for patients
during an episode of severe back pain
•  Allows patients to progress in their rehabilitation
Lumbar epidural injection
•  18G or 16G Toohey
needle
•  Radio-opaque contrast
to confirm position
•  Injection and
distribution of local
anaesthetic and
steroid to nerve root
Lumbar	
  Epidural	
  Injec'on	
  
Caudal	
  Epidural	
  Injec'on	
  
Facet joint injections
•  Back pain originating from facet joints
•  Low back pain (unilateral or bilateral) and no
root tension signs or neurological deficits
•  Pain usually being aggravated by extension of
the spine
•  Facet joint injection may reduce inflammation
and provide pain relief
•  Therapeutic goal and potential benefit
–  Temporary relief from pain
–  Patient may proceed into an appropriate exercise program"
Facet	
  Joint	
  Injec'on	
  
•  Primarily	
  diagnos'c	
  
•  25G	
  Spinal	
  needle	
  	
  
•  LA	
  +	
  Steroid	
  
•  Steroid	
  confers	
  possible	
  
longer	
  term	
  benefit	
  
Sacroiliac joint injection
•  Indicated with referred pain
•  Pain referral pattern – area around and just
caudal to the posterior superior iliac spine
•  Referred pain in the low back, buttocks,
abdomen, groin or legs
•  In some patients, S-1 joint injections can
provide significant pain relief"
Sacroiliac joint injection
•  Diagnostic
•  25G spinal needle
•  Local anaesthetic +
steroid
•  Steroid indicative of
possible long-term
benefit
Sacro-­‐iliac	
  Joint	
  Injec'on	
  
Medial branch blocks
•  Medial branch nerves are the very small nerve
branches that controls sensation of the facet joint
•  Indicated in low back pain (unilateral or bilateral)
•  Pain usually aggravated by extension of the spine
•  Medial branch blocks are a diagnostic procedure
•  Can provide temporary pain relief
Medial branch nerve ablation
•  Diagnostic medial
branch blocks
•  Local anaesthetic +
steroid
•  Progress to
radiofrequency
ablation if diagnostic
block indicative of
long-term benefit
Medial	
  Branch	
  Nerve	
  Abla'on	
  
•  Denerva'on	
  of	
  Medial	
  
Branch	
  via	
  
Radiofrequency	
  
Neurotomy	
  
Radiofrequency neurotomy
X-ray to confirm needle position – AP and oblique
views
Test stimulation – 2.0 Hz 0–2 volt to test for motor
nerve contact
Lesion 85°C for 90 seconds
Cervical radiofrequency neurotomy
Position for C2/3 and C3/4 facet joint
radiofrequency
Cervical	
  Radiofrequency	
  Neurotomy	
  
Cervical radiofrequency neurotomy –
lateral view
Marker shows needle at C2/3 facet joint
Coeliac	
  Plexus	
  Block	
  
Facet joint injection
•  Diagnostic
•  25G spinal needle
•  Local anaesthetic +
steroid
•  Steroid indicative of
possible long-term
benefit
Elena Yusim – Pain Psychologist
The Psychology of Pain
Management
Strategy
Psychosocial	
  Assessment	
  	
  
§  	
  medical	
  history	
  –	
  any	
  flags/concerns/drug	
  seeking	
  
§  Thinking	
  paNerns	
  –	
  helpful	
  or	
  unhelpful	
  
§  Social	
  interac'ons	
  -­‐	
  family,	
  friends,	
  spouse	
  
§  Behaviours	
  -­‐	
  	
  ac'vity	
  levels,	
  avoidance,	
  anything	
  harmful	
  
§  Sleep	
  paNerns	
  –	
  any	
  changes	
  	
  	
  
Testing
§  Beck	
  Depression	
  Inventory	
  –	
  BDI	
  
§  Depression,	
  Anxiety	
  and	
  Stress	
  Scale	
  –	
  DASS	
  
§  Personality	
  Assessment	
  Inventory	
  -­‐	
  PAI	
  
Reality Check
§  Why	
  is	
  the	
  pa'ent	
  here?	
  
§  Mo'va'on	
  to	
  RTW?	
  
§  Any	
  secondary	
  gain	
  from	
  sick	
  role?	
  
§  Are	
  they	
  prepared	
  to	
  do	
  the	
  hard	
  work?	
  
§  Do	
  they	
  expect	
  to	
  be	
  fixed?	
  
§  What	
  do	
  they	
  agree	
  to,	
  if	
  they	
  don’t	
  comply?	
  
Invisible Tool Kit
§  Goal	
  seng	
  
§  Pacing	
  
§  Journaling	
  
§  Thought	
  Management	
  –	
  CBT,	
  ACT	
  
§  Relaxa'on	
  	
  and	
  self	
  regula'on	
  strategies	
  
§  Relapse	
  preven'on	
  planning	
  	
  
Opioids	
  in	
  Chronic	
  Pain	
  	
  
	
  
Dr	
  Brendan	
  Moore	
  
Pain	
  Medicine	
  Specialist	
  Physician	
  
Adjunct	
  Associate	
  Professor	
  
	
  University	
  of	
  Queensland	
  
Opioid prescribing:
dose limits and
considerations	
  
Suggested maximum opioid dose
•  Consult a Pain Medicine Specialist if higher doses
considered necessary
1. Hunter Integrated Pain Service. Opioid use in persistent pain. November 2010
Drug Maximum dose for GP
prescription
Morphine 120mg daily
Oxycodone 80mg daily
Hydromorphone 24 mg daily
Methadone 40mg daily
Fentanyl transdermal patch 25 mcg/hr applied every 3 days
Buprenorphine transdermal patch 40 mcg/hr applied weekly
Tramadol 400 mg daily
Dose conversion
Morphine
equivalence to
Ratio
morphine
: named
opioid
Examples of equivalent doses
Codeine 1:6 Morphine 10 mg Codeine 60 mg
Oxycodone 1.5:1 Morphine 60 mg Oxycodone 40 mg
Hydromorphone 5:1 Morphine 60 mg Hydromorphone 12 mg
Tramadol 1:5 Morphine 10 mg Tramadol 50 mg
Fentanyl Morphine 90 mg Fentanyl 25 mcg/h
Buprenorphine 75:1 Morphine 9 mg Buprenorphine 5 mcg/h
Methadone 3:1 Morphine 60 mg Methadone 20 mg
1. Hunter Integrated Pain Service. Opioid use in persistent pain. November 2010
Opioid trial guidelines
•  Commence trial with low dose sustained-release
opioid
Use a lower dose and titrate slowly in patients
who are:
•  Elderly
•  Taking other CNS depressants
•  Opioid naïve
•  Have severe hepatic or renal dysfunction
1.  Graziotti & Goucke, 1997.
Review of opioid trial
•  Discuss progress and outcomes
•  Functional goals achieved?
•  Medication used responsibly?
•  Discuss risks / benefits of continued therapy
•  Assess 4 ‘A’s1
–  Analgesia
–  Activity
–  Adverse effects
–  Aberrant drug behaviours
1. Gourlay & Heit, 2005.
Federal requirements
PBS prescription
Restricted benefit
•  Chronic severe disabling pain not responding to non-
narcotic analgesics (treatment <12 months)
•  If treatment required beyond 12 months, patient must be
reviewed by a second medical practitioner
•  Authority required when prescribing increased quantities
of opioid and/or repeats
–  By phone – 1 month’s supply with no repeats
–  In writing – 1 month’s supply with 2 repeats
•  Short term supply can be prescribed without an authority
Department of Health and Ageing, 2008.
State requirements - QLD
•  If intend to prescribe S8 drugs for longer than 8 weeks,
forward a “Report to the Chief Executive” through the
Drugs of Dependence Unit (DDU)
•  A treatment approval from the Chief Executive is required
prior to treating, for any controlled drug for a patient
considered to be drug dependent
•  For approvals and “Reports to the Chief Executive” contact
the Drugs of Dependence Unit
–  Phone 3328 9890
–  Fax 3328 9821
Preventing doctor-shopping
Medicare Australia
Prescription Shopping Information Service
•  If patient suspected of getting medicine in excess
of medical need, contact the Prescription
Shopping Information Service:
–  Complete and sign the registration form available at
www.medicareaustralia.gov.au
•  Registration confirmed within 2 business days (fax) or by
mail
–  Information Service available 24/7 for registered GPs to:
•  Find out if patient has been identified under the
Prescription Shopping Program
•  Receive information on the amount and type of PBS
medicine recently supplied to that patient
(	
  1800	
  631	
  181	
  	
  
Summary – opioid pathway
Multidimensional assessment
GP +/– practice nurse +/– others
Opioid trial
Maintenance therapy
Authority to Prescribe
Review
Exit from pathway:
i.  Goals of therapy not
achieved in trial or
maintenance phase
ii.  Predominance of
psychosocial issues
iii.  Evidence of aberrant
drug related
behaviour
Integrated Pain Service, 2008.
Is the patient suitable for opioid therapy?
State / territory health departments
State /
territory
Department Contact
ACT Pharmaceutical Services Section, ACT Health ( 02 6207 3974
NSW Pharmaceutical Services Branch, NSW Health ( 02 9879 3214
8 www.health.nsw.gov.au/publichealth/
pharmaceutical
NT Poisons Control Unit, Department of Health &
Community Services
( 08 8922 7341
8 www.health.nt.gov.au
QLD Drugs of Dependency Unit, Queensland Health ( 07 3896 3900
SA Drugs of Dependence Unit, Drug & Alcohol Services,
Department of Health
( 1300 652 584
8 www.health.sa.gov.au
TAS Pharmaceutical Services Branch, Department of
Health & Human Services
( 03 6233 2064
VIC Drugs & Poisons Unit, Department of Human
Services
( 1300 364 545
8 www.health.vic.gov.au/dpu
WA Drugs of Dependency Unit, Department of Health ( 08 9388 4985

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Pain management

  • 1. Interven'onal   Procedures  in  Chronic   Pain       Dr  Brendan  Moore   Specialist  Pain  Medicine  Physician   Adjunct  Associate  Professor    University  of  Queensland  
  • 3.
  • 4. Origins  of  lumbar  pain   •  Degenera've  Discs   •  Vertebral  fractures   •  Spinal  /  Foraminal   Stenosis   •  Disc  Bulge  /  Prolapse   •  Facet  Joint     •  Muscle  /  So@  'ssue    
  • 5. Invasive  Treatment  Op'ons   •  Surgery   •  Facet  Joint  Injec'on   •  Radiofrequency  medial  branch  abla'on   •  Epidural  /  Caudal  steroid   •  Vertebroplasty   •  Coeliac  /  Lumbar  Sympathe'c  Plexus  Blocks   •  Sacro-­‐iliac  Joint  injec'on  
  • 6. Posterior  Elements   •  Facet  Joints  frequently  implicated  in  pain   •  Mechanical  back  pain  with  upper  leg  and  buNock   radia'on  
  • 7. Appropriate conditions for interventional pain procedures •  Aseptic conditions •  Monitored sedation with anaesthetist in attendance •  Image intensifying X- ray or CT guidance •  Appropriate analgesia
  • 8.
  • 9.
  • 10. Procedures •  Epidural injections –  Cervical, Thoracic, Lumbar, Caudal •  Facet joint injections •  Sacroiliac joint injections •  Medial branch blocks •  Radiofrequency nerve ablation
  • 11. Epidural injections •  Most effective in the presence of nerve root compression and spinal stenosis •  Increased efficacy if given in the first weeks of the onset of pain •  Effects of the injection tend to be temporary (1 week to 1 year) •  Can be beneficial in providing relief for patients during an episode of severe back pain •  Allows patients to progress in their rehabilitation
  • 12. Lumbar epidural injection •  18G or 16G Toohey needle •  Radio-opaque contrast to confirm position •  Injection and distribution of local anaesthetic and steroid to nerve root
  • 15. Facet joint injections •  Back pain originating from facet joints •  Low back pain (unilateral or bilateral) and no root tension signs or neurological deficits •  Pain usually being aggravated by extension of the spine •  Facet joint injection may reduce inflammation and provide pain relief •  Therapeutic goal and potential benefit –  Temporary relief from pain –  Patient may proceed into an appropriate exercise program"
  • 16. Facet  Joint  Injec'on   •  Primarily  diagnos'c   •  25G  Spinal  needle     •  LA  +  Steroid   •  Steroid  confers  possible   longer  term  benefit  
  • 17. Sacroiliac joint injection •  Indicated with referred pain •  Pain referral pattern – area around and just caudal to the posterior superior iliac spine •  Referred pain in the low back, buttocks, abdomen, groin or legs •  In some patients, S-1 joint injections can provide significant pain relief"
  • 18. Sacroiliac joint injection •  Diagnostic •  25G spinal needle •  Local anaesthetic + steroid •  Steroid indicative of possible long-term benefit
  • 20. Medial branch blocks •  Medial branch nerves are the very small nerve branches that controls sensation of the facet joint •  Indicated in low back pain (unilateral or bilateral) •  Pain usually aggravated by extension of the spine •  Medial branch blocks are a diagnostic procedure •  Can provide temporary pain relief
  • 21. Medial branch nerve ablation •  Diagnostic medial branch blocks •  Local anaesthetic + steroid •  Progress to radiofrequency ablation if diagnostic block indicative of long-term benefit
  • 22. Medial  Branch  Nerve  Abla'on   •  Denerva'on  of  Medial   Branch  via   Radiofrequency   Neurotomy  
  • 23. Radiofrequency neurotomy X-ray to confirm needle position – AP and oblique views Test stimulation – 2.0 Hz 0–2 volt to test for motor nerve contact Lesion 85°C for 90 seconds
  • 24. Cervical radiofrequency neurotomy Position for C2/3 and C3/4 facet joint radiofrequency
  • 26. Cervical radiofrequency neurotomy – lateral view Marker shows needle at C2/3 facet joint
  • 28. Facet joint injection •  Diagnostic •  25G spinal needle •  Local anaesthetic + steroid •  Steroid indicative of possible long-term benefit
  • 29.
  • 30.
  • 31. Elena Yusim – Pain Psychologist The Psychology of Pain Management
  • 32. Strategy Psychosocial  Assessment     §   medical  history  –  any  flags/concerns/drug  seeking   §  Thinking  paNerns  –  helpful  or  unhelpful   §  Social  interac'ons  -­‐  family,  friends,  spouse   §  Behaviours  -­‐    ac'vity  levels,  avoidance,  anything  harmful   §  Sleep  paNerns  –  any  changes      
  • 33. Testing §  Beck  Depression  Inventory  –  BDI   §  Depression,  Anxiety  and  Stress  Scale  –  DASS   §  Personality  Assessment  Inventory  -­‐  PAI  
  • 34. Reality Check §  Why  is  the  pa'ent  here?   §  Mo'va'on  to  RTW?   §  Any  secondary  gain  from  sick  role?   §  Are  they  prepared  to  do  the  hard  work?   §  Do  they  expect  to  be  fixed?   §  What  do  they  agree  to,  if  they  don’t  comply?  
  • 35. Invisible Tool Kit §  Goal  seng   §  Pacing   §  Journaling   §  Thought  Management  –  CBT,  ACT   §  Relaxa'on    and  self  regula'on  strategies   §  Relapse  preven'on  planning    
  • 36. Opioids  in  Chronic  Pain       Dr  Brendan  Moore   Pain  Medicine  Specialist  Physician   Adjunct  Associate  Professor    University  of  Queensland  
  • 37. Opioid prescribing: dose limits and considerations  
  • 38. Suggested maximum opioid dose •  Consult a Pain Medicine Specialist if higher doses considered necessary 1. Hunter Integrated Pain Service. Opioid use in persistent pain. November 2010 Drug Maximum dose for GP prescription Morphine 120mg daily Oxycodone 80mg daily Hydromorphone 24 mg daily Methadone 40mg daily Fentanyl transdermal patch 25 mcg/hr applied every 3 days Buprenorphine transdermal patch 40 mcg/hr applied weekly Tramadol 400 mg daily
  • 39. Dose conversion Morphine equivalence to Ratio morphine : named opioid Examples of equivalent doses Codeine 1:6 Morphine 10 mg Codeine 60 mg Oxycodone 1.5:1 Morphine 60 mg Oxycodone 40 mg Hydromorphone 5:1 Morphine 60 mg Hydromorphone 12 mg Tramadol 1:5 Morphine 10 mg Tramadol 50 mg Fentanyl Morphine 90 mg Fentanyl 25 mcg/h Buprenorphine 75:1 Morphine 9 mg Buprenorphine 5 mcg/h Methadone 3:1 Morphine 60 mg Methadone 20 mg 1. Hunter Integrated Pain Service. Opioid use in persistent pain. November 2010
  • 40. Opioid trial guidelines •  Commence trial with low dose sustained-release opioid Use a lower dose and titrate slowly in patients who are: •  Elderly •  Taking other CNS depressants •  Opioid naïve •  Have severe hepatic or renal dysfunction 1.  Graziotti & Goucke, 1997.
  • 41. Review of opioid trial •  Discuss progress and outcomes •  Functional goals achieved? •  Medication used responsibly? •  Discuss risks / benefits of continued therapy •  Assess 4 ‘A’s1 –  Analgesia –  Activity –  Adverse effects –  Aberrant drug behaviours 1. Gourlay & Heit, 2005.
  • 42. Federal requirements PBS prescription Restricted benefit •  Chronic severe disabling pain not responding to non- narcotic analgesics (treatment <12 months) •  If treatment required beyond 12 months, patient must be reviewed by a second medical practitioner •  Authority required when prescribing increased quantities of opioid and/or repeats –  By phone – 1 month’s supply with no repeats –  In writing – 1 month’s supply with 2 repeats •  Short term supply can be prescribed without an authority Department of Health and Ageing, 2008.
  • 43. State requirements - QLD •  If intend to prescribe S8 drugs for longer than 8 weeks, forward a “Report to the Chief Executive” through the Drugs of Dependence Unit (DDU) •  A treatment approval from the Chief Executive is required prior to treating, for any controlled drug for a patient considered to be drug dependent •  For approvals and “Reports to the Chief Executive” contact the Drugs of Dependence Unit –  Phone 3328 9890 –  Fax 3328 9821
  • 44. Preventing doctor-shopping Medicare Australia Prescription Shopping Information Service •  If patient suspected of getting medicine in excess of medical need, contact the Prescription Shopping Information Service: –  Complete and sign the registration form available at www.medicareaustralia.gov.au •  Registration confirmed within 2 business days (fax) or by mail –  Information Service available 24/7 for registered GPs to: •  Find out if patient has been identified under the Prescription Shopping Program •  Receive information on the amount and type of PBS medicine recently supplied to that patient (  1800  631  181    
  • 45. Summary – opioid pathway Multidimensional assessment GP +/– practice nurse +/– others Opioid trial Maintenance therapy Authority to Prescribe Review Exit from pathway: i.  Goals of therapy not achieved in trial or maintenance phase ii.  Predominance of psychosocial issues iii.  Evidence of aberrant drug related behaviour Integrated Pain Service, 2008. Is the patient suitable for opioid therapy?
  • 46. State / territory health departments State / territory Department Contact ACT Pharmaceutical Services Section, ACT Health ( 02 6207 3974 NSW Pharmaceutical Services Branch, NSW Health ( 02 9879 3214 8 www.health.nsw.gov.au/publichealth/ pharmaceutical NT Poisons Control Unit, Department of Health & Community Services ( 08 8922 7341 8 www.health.nt.gov.au QLD Drugs of Dependency Unit, Queensland Health ( 07 3896 3900 SA Drugs of Dependence Unit, Drug & Alcohol Services, Department of Health ( 1300 652 584 8 www.health.sa.gov.au TAS Pharmaceutical Services Branch, Department of Health & Human Services ( 03 6233 2064 VIC Drugs & Poisons Unit, Department of Human Services ( 1300 364 545 8 www.health.vic.gov.au/dpu WA Drugs of Dependency Unit, Department of Health ( 08 9388 4985