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PRE TEST QUESTIONS
• State true or false
1. In an Elderly diabetic male coming with short history of retrosternal crushing
chest pain acute gastritis is your first differential diagnosis
2. A detailed and elaborate cardiovascular examination is a must in acute MI ?
• State true or false
3. The earliest cardiac enzyme to elevate and decrease is troponin I
4. Oxygen should be provided for all MI patients
5. All patients with MI should receive antiplatelets as a early as possible if no
contraindications
6. Thrombolysis is the preferred treatment in all patients of MI?
CASE
Doc is it gastritis ????????
• 56 year old male
• c/o acute onset chest pain since 1 hour with minimal dyspnea
• Past history : HTN since 10 years , DM since 5 years
• Family : nothing contributory
• Personal : smoking 10 pack years per day
EXAMINATION
• PR : 108 / min
• BP : 120 /80
• RR: 20/min
• SPO2 : 96 % on RA
•Pale
•Diaphoretic
•JVP: Not elevated
CVS
AUSCULTATION OF LUNGS
• Normal vesicular breath sounds heard
ECG
LABS
• Normal Troponin and CKMB levels
DIAGNOSIS
Acute ST Elevation Myocardial
Infarction
ACUTE CORONARY
SYNDROME
DR SOURAB HIREMATH
MD INTERNAL MEDICINE
EMERGENCY MEDICINE
ACUTE STEMI
Acute Myocardial infarction characterised by ST
segment elevation of more than 1 mm In two
contiguous leads
ETIOLOGY / RISK FACTORS
PATHOPHYSIOLOGY
CLINICAL FEATURES
CHEST PAIN
Retrosternal
Radiation
Severe crushing type
CLINICAL FEATURES
• Dyspnea
• Diaphoresis
• Palpitation
• Lightheadedness
• Nausea
• Vomiting
CLINICAL FEATURES
• Examination should be quick assessment as acute presentation usually has no
CVS findings
• Mechanical complications will produce CVS findings
ECG
• ST segment elevation of more than 1 mm in 2 contiguous leads
• Or new onset LBBB
LABORATORY
• CBC : mild leucocytosis
• Lipid profile : LDL elevation
CARDIAC ENZYMES
2D ECHO
TREATMENT
TIME is MUSCLE
GOLDEN RULE OF EMERGENCY MEDICINE
ABC
In cardiac arrest
CAB
PRIOR TO MEDICATIONS
PRIOR TO REPERFUSION TREATMENT
ASPIRIN 325 mg tablet
LOADING DOSE of oral P2Y12 antagonists
Eg. Clopidogrel 75 mg 4 tablets
High dose Statins 40-80 mg stat
OXYGEN
?????
<94%
NITROGLYCERIN
• Oral : GTN 2.6 mg every 5- 10 mins
• Intravenous infusion 5-10 mcg
REDUCING MYOCARDIAL OXYGEN DEMAND
Beta blockers
PAIN RELIEF
MORPHINE
REPERFUSION THERAPY
FIBRINOLYTICS VS PERCUTANEOUS CORONARY INTERVENTION
DOOR TO Drug time 30 mins Door to balloon time 90 mins
Time period <12 hours
THROMBOLYTICS
PERCUTANEOUS CORONARY INTERVENTION
THANK YOU

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ACS:STEMI