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Sompop	
  Bencharit,	
  DDS,	
  MS,	
  PhD,	
  FACP	
  
Curriculum	
  Vitae,	
  Page	
  1	
  of	
  19	
  
	
   	
  
CURRICULUM VITAE (8/2015)
SOMPOP BENCHARIT, DDS, MS, PhD, FACP
PERSONAL HISTORY
Citizenship: USA
Office Address: Tel: (919) 537-3961
Fax: (919) 537-3977
Rm 342 Brauer Hall, CB#7450
Department of Prosthodontics,
School of Dentistry
University of North Carolina at Chapel Hill
Chapel Hill, NC 27599-3290
Email: Sompop_Bencharit@unc.edu
Website: http://benchars.wix.com/prosth
Home Address: 112 Westgreen Dr.,
Chapel Hill, NC 27516
EDUCATION
Institution and Location Degree Date Conferred Major
University of North Carolina Research Scholar 2008 Clinical Research
at Chapel Hill
School of Dentistry
University of North Carolina Postdoctoral Fellow 2004 Structural Biology/
at Chapel Hill Prosthodontics
Department of Chemistry
University of North Carolina PhD 2003 Oral Biology
at Chapel Hill
School of Dentistry
University of North Carolina MS 1999 Prosthodontics
at Chapel Hill
School of Dentistry
University of North Carolina Certificate 1999 Prosthodontics
at Chapel Hill
School of Dentistry
Chulalongkorn University Graduate 1996 Prosthodontics
Bangkok, Thailand Diploma
Chulalongkorn University DDS 1994 Dentistry
Bangkok, Thailand
Sompop	
  Bencharit,	
  DDS,	
  MS,	
  PhD,	
  FACP	
  
Curriculum	
  Vitae,	
  Page	
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Licensure and Certification
2005- North Carolina Dental Practice License (Instructor Privilege License #0030)
1994- Thailand Dental Practice License
Specialty Certification
2009- Fellow, American College of Prosthodontists
2009- Diplomate, American Board of Prosthodontics
PROFESSIONAL EXPERIENCE
Academic Appointments
2012- Assistant Professor (tenure-track), Department of Prosthodontics,
School of Dentistry, University of North Carolina
2012- Adjunct Assistant Professor, Department of Pharmacology,
School of Medicine, University of North Carolina
2005-2012 Research Assistant Professor, Department of Prosthodontics,
School of Dentistry, University of North Carolina
2005-2012 Adjunct Research Assistant Professor, Department of Pharmacology,
School of Medicine, University of North Carolina
2003-2005 Postdoctoral Fellow/Clinical Instructor, Department of Chemistry and Department of
Prosthodontics, University of North Carolina
2001-2003 PhD Candidate, Oral Biology, School of Dentistry, University of North Carolina
Dissertation Title: “Structure and Function of Mammalian Carboxylesterases”
2000-2003 Research Assistant, Redinbo lab, Department of Chemistry, University of North
Carolina
1999-2003 Graduate Student and Research Assistant, Oral Biology, School of Dentistry,
University of North Carolina
1998-1999 Chief Resident, Graduate Prosthodontics, Department of Prosthodontics,
School of Dentistry, University of North Carolina
1997-1999 Clinical and Laboratory Teaching Assistant, Department of Prosthodontics,
School of Dentistry, University of North Carolina
1996-1999 Graduate Student, Department of Prosthodontics, School of Dentistry, University of
North Carolina
Thesis Title: “Radiographic Evaluation of Peri-implant Bone”
1994-1996 Lecturer, Chulalongkorn University, Bangkok, Thailand
Hospital Appointment
2006- University of North Carolina Hospitals
Private Practice
2005- University of North Carolina Dental Faculty Practice
HONORS
2013 University of North Carolina Junior Faculty Award
2011-2012 North Carolina Translational and Clinical Sciences Institute (NCTraCS) Pilot Grant
Sompop	
  Bencharit,	
  DDS,	
  MS,	
  PhD,	
  FACP	
  
Curriculum	
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2009-2011 American Recovery and Reinvestment Act Grant
2006-2008 NIH Clinical Research Scholar Award (T32), UNC-School of Dentistry
2003 Paul Sigler Award, The Best Student Poster Award, The 31st
Mid-Atlantic
Crystallography Meeting, Duke University, Durham, NC
2002 Hatton Award Candidate (American section), American Association of Dental Research
2001 Travel Grant Award, American Crystallography Association Meeting, Los Angles, CA
1999 Second-place winner, John J. Sharry Research Competition, American College of
Prosthodontists Annual Meeting, New York
1998 Procter and Gamble Research Fellowship in Complete Denture Prosthodontics, American
College of Prosthodontists
1998-2003 “King Ananda Mahidol” Scholarship, under the royal patronage of HRH King Bhumipol
of Thailand, the best graduate student in dentistry
BIBLIOGRAPHY
Journal Articles (*Refereed)
1* Barrero C, Bencharit S, Petrola F. Case Report: Screw-Retained Zirconia Implant Restoration.
J Oral Implantol. (in press)
2* Bencharit S, Byrd W, Hosseini B. Immediate placement of a porous-tantalum, trabecular metal-
enhanced titanium dental implant with demineralized bone matrix into a socket with deficient
buccal bone: A clinical report. J Prosthet Dent 2015;113:262-9.
3* Hosseini B, Byrd W, Preisser JS, Khan A, Duggan D, Bencharit S. Effects of Antibiotics on Bone
and Soft Tissue Healing Following Immediate Single-tooth Implant Placement into Sites with
Apical Pathology. J Oral Implantol. (in press)
4* Byrd WC, Schwartz-Baxter S, Carlson J, Barros S, Offenbacher S, Bencharit S. Role of salivary
and candidal proteins in denture stomatitis: an exploratory proteomic analysis. Mol Biosyst.
2014;10:2299-304.
5* Baxter SS, Dibble CF, Byrd WC, Carlson J, Mack CR, Bencharit S. Role of cytoskeletal proteins in
cerebral cavernous malformation signaling pathways: a proteomic analysis. Mol Biosyst 2014;
10:1881-92.
6* Edelmann AR, Baxter SS, Dibble CF, Byrd WC, Carlson, Saldarriaga I, Bencharit S. Systems
biology proteomic analysis of cerebral cavernous malformation. Exp Rev Proteomics 2014;11:
395-404.
7* Bencharit S, Border MB, Mack CR, Byrd WC, Wright JT. Full mouth rehabilitation for a patient
with dentinogenesis imperfecta: A clinical report. J Oral Implantol 2014;40:593-600.
8* Frazier-Bowers, SA, Wright JT, Hendricks HM, Lee J, Long K, Dibble CF, Bencharit S. Novel
mutations in PTH1R associated with primary failure of eruption and osteoarthritis. J Dent Res
2014;93:134-9.
9* Bencharit S, Border MB, Edelmann AR. Update in Research and Methods in Proteomics and
Bioinformatics. Expert Rev Proteomics 2013;10:413-5.
10* Hobbs CA, Blanchard MG, Alijevic O, Tan CD, Kellenberger S, Bencharit S, Cao R, Kesimer M,
Walton WG, Henderson AG, Redinbo MR, Stutts MJ, Tarran R. Identification of SPLUNC1's
ENaC-Inhibitory Domain Yields Novel Strategies to Treat Sodium Hyperabsorption in Cystic
Fibrosis Airway Cultures. Am J Physiol Lung Cell Mol Physiol. Am J Physiol Lung Cell Mol
Physiol. 2013;305:L990-L1001.
11* Bencharit S, Baxter SS, Carlson J, Byrd WC, Mayo MV, Border MB, Kohltfarber H, Urrutia E,
Howard-Williams EL, Offenbacher S, Wu MC, Buse JB. Salivary proteins associated with
hyperglycemia in diabetes: a proteomic analysis. Mol Biosyst, 2013 9:2785-97.
Sompop	
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  MS,	
  PhD,	
  FACP	
  
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12* Garland EA, Walton WG, Coakley RD, Tan CD, Gilmore RC, Hobbs CA, Tripathy, Betts L,
Clunes LA, Bencharit S, Stutts MJ, Redinbo MR, Tarran R. Molecular Basis for pH-Dependent
Mucosal Dehydration in Cystic Fibrosis Airways. Proc Natl Acad Sci USA 2013:110:15973-8.
13* Givens E, Bencharit S, Byrd WC, Phillips C, Hosseini B, Tyndall D. Immediate placement and
provisionalization of implants into sites with periradicular infection with and without antibiotics:
An exploratory study. J Oral Implantol 2015;41:299-305.
14* Bencharit S, Byrd WC, Al-Tarawneh SK, Hosseini B, Leong A, Reside G, Morelli T, Offenbacher
S. Development and applications of porous tantalum trabecular metal enhanced titanium dental
implants. Clin Implant Dent Relat Res 2014;16:817-26.
15* Al-Tarawneh SK, Bencharit S, Barros S, Loewy Z, Gendreau L, Offenbacher S. Clinical and
Histological Findings of Denture Stomatitis as Related to Intraoral Colonization Patterns of C.
albicans, Salivary Flow and Dry Mouth. J Prosthodont. 2013:22;13–22.
16* Barros S, Al-Tarawneh SK, Bencharit S, Loewy Z, Gendreau L, Offenbacher S.Salivary Cytokines
and levels in in denture stomatitis: an exploratory case-control study. Open J Stomatol
2012:2;326-333.
17* Bencharit S, Border MB. Where are we in the World of Proteomics and Bioinformatics? Expert
Rev Proteomics 2012;9:489-91.
18 Bencharit S. The Discovery of Insulin and the Future for Insulin Replacement Therapy. Int J Clin
Pharmacol Toxicol 2012;1:101.
19 Bencharit S. History of Progress and Challenges in Structural Biology. J Pharmacogenom
Pharmacoproteomics 2012;S4:e001. doi 10.4172/2153-0645.S4-e001.
20 Bencharit S. Bacterial Resistance to Antibiotics and Implanted Medical Devices. Adv
Pharmacoepidem Drug Safety 2012;1:e112. doi:10.4172/2167-1052.1000e112.
21 Bencharit S, Byrd WC. Oral and craniofacial stem cells: where we are in understanding molecular
signaling and clinical applications. Stem Cells Oral Med 2012; 1-2. doi: 10.2478/scom-2012-0001.
22 Bencharit S. Challenges and Prospective Applications of Extra-oral Implants for Maxillofacial
Rehabilitation. Anaplastology 2012;1:e103. doi: 10.4172/2161-1173.1000e103.
23 Bencharit S. Progresses and Challenges of Omics Studies and Their Impacts in Personalized
Medicine. J Pharmacogenom Pharmacoproteomics 2012;3:e105. doi:10.4172/2153-0645.1000e105.
24* Bencharit S, Al-Tarawneh SK, Schwartz S, Carlson J, Ross GF, Border MB, Mack CR, Byrd WC,
Dibble CF, Barros S, Loewy Z, Offenbacher S. Elucidating role of salivary proteins in denture
stomatitis using proteomic approach. Mol Biosyst. 2012;8:3216-3223.
25* Hobbs C, Blanchard M, Kellenberger S, Bencharit S, Cao R, Kesimer M, Walton WG, Redinbo
MR, Stutts MJ, Tarran R. Identification of SPLUNC1’s ENaC-inhibitory domain yields novel
strategies to treat sodium hyperabsorption in cystic fibrosis airways. FASEB J 2012;26:4348-59.
26* Border MB, Schwartz S, Carlson J, Kohltfarber H, Offenbacher S, Buse JB, Bencharit S. Exploring
Salivary Proteomes in Edentulous Patients with Type 2 Diabetes. Mol Biosyst. 2012;8:1304-10.
27* Bencharit S, Howard-Williams EL, Mack CR. Recent Studies and Patents in Salivary Protein
Biomarkers for Diabetes. Recent Patents Biomarkers. 2012;2:1-5.
28* Bencharit S, Misiek DJ, Simon LA, Malone-Trahey A. Comprehensive multidisciplinary approach
for a patient with severe skeletal class III: A clinical report. J Oral Implantol. 2012;38:63-70.
29* Al-Tarawneh SK, Border MB, Dibble CF, Bencharit S. Defining salivary biomarkers using mass
spectrometry-based Proteomics : a systematic review. OMICS 2011;15:353-61.
30* Barrero C, Border MB, Bencharit S. Fabrication of a maxillary implant-retained prosthesis using an
existing subperiosteal implant: A clinical report. Open Dent. 2011;5:122-5.
31 Bencharit S. How Academic Dentistry will Emerge from this Economic Crisis? Dentistry
2011;1:e101. doi:10.4172/2161-1122.1000e101
32* Dibble CF, Horst JA, Malone MH, Park K, Temple B, Cheeseman H, Barbaro JR, Johnson GL,
Bencharit S. Defining the functional domain of programmed cell death 10 through its interaction
with phosphatidylinositol-3,4,5-trisphosphate. PLOS ONE 2010;5:e1174.
Sompop	
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  DDS,	
  MS,	
  PhD,	
  FACP	
  
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33* Wang Z, Pan J, Wright JT, Bencharit S, Zhang S, Everett ET, Teixeira FB, Preisser JS. Putative
stem cells in human dental pulp with irreversible pulpitis-an exploratory study. J. Endod.
2010;36:820-5.
34* Borikova AL, Dibble CF, Sciaky N, Welch CM, Abell AN, Bencharit S, Johnson GL. Rho kinase
inhibition rescues the endothelial cell cerebral cavernous malformation phenotype. J Biol. Chem.
2010;285:11760-4.
35* Bencharit S, Schardt-Sacco D, Barbaro CP, Border MB. Early placement of dental implants in a
patient with severe periodontitis: A Case Report. Open Dent J. 2010;4:165-71.
36* Bencharit S, Reside GJ, Howard-Williams EL. Complex prosthodontic treatment with dental
implants for a patient with polymyalgia rheumatica: A clinical report. Int J Maxillofac Implants.
2010;25:1241-5.
37* Patel M, Bencharit S. Removable partial overdentures, an alternative to full mouth reconstruction:
A Clinical Report. Open Dent J 2009;3:213-8.
39* Al-Tarawneh SK, Bencharit S. Applications of SELDI-TOF mass spectrometry in salivary
proteomic analysis. Open Dent J 2009; 3:74-79.
39* Hilder TL, Malone MH, Bencharit S, Colicelli J, Haystead TA, Johnson GL, Wu CC. Proteomic
Identification of the Cerebral Cavernous Malformation Signaling Complex. J. Proteome Res.
2007;6:4343-55.
40* Xue Y, Moore YB, Orans J, Peng L, Bencharit S, Kliewer SA, Redinbo MR. Crystal Structure of
the PXR-Estradiol Complex Provides Insights into Endobiotic Recognition. Mol. Endocrinol.
2007:21;1028-38.
41* Bencharit S, Cui CB, Siddiqui A, Howard-Williams EL, Sondek J, Zuobi-Hasona, K, Aukhil I.
Structural insights into fibronectin type III domain mediated signaling. J. Mol. Biol. 2007:367;
303-9.
42* Bencharit S. A young faculty member's perspective of academic prosthodontics. J. Prosthodont.
2007;16:417-8.
43* Bencharit S, Edwards CC, Morton CL, Howard-Williams EL, Kuhn P, Potter PM, Redinbo MR.
Multisite promiscuity in the processing of endogeneous substrates by human carboxylesterase 1. J.
Mol. Biol. 2006;363:201-14.
44* Fleming CD, Bencharit S, Edwards CC, Hyatt JL, Tsurkan L, Bai F, Fraga C, Morton CL, Howard-
Williams EL, Potter PM, Redinbo MR. Structural insights into drug processing by human
carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil. J. Mol. Biol. 2005;352:165-77.
45* Uhlik MT, Temple B, Bencharit S, Kimple A, Siderovski D, Johnson GL. Structural and
Evolutionary Division of Phosphotyrosine Binding (PTB) Domains. J. Mol. Biol. 2005;345:1-20.
46* Bencharit S, Schardt-Sacco D, Zuniga JR, Minsley GE. Surgical and prosthodontic rehabilitation
for a patient with aggressive florid cemento-osseous dysplasia: a case report. J. Prosthet. Dent.
2003;90:220-4.
47* Redinbo MR, Bencharit S, Potter PM. Human carboxylesterase 1: from drug metabolism to drug
discovery. Biochem. Soc. Trans. 2003;31:620-24.
48* Bencharit S, Morton CL, Hyatt JL, Kuhn P, Danks MK, Potter PM, Redinbo MR. Crystal Structure
of Human Carboxylesterase 1 Complexed with the Alzheimer’s Drug Tacrine: From Binding
Promiscuity to Selective Inhibition. Chem. Biol. 2003;10:341-9.
49* Bencharit S, Morton CL, Xue Y, Potter PM, Redinbo MR. Structural Basis of Heroin and Cocaine
Metabolism by a Promiscuous Human Drug-Processing Enzyme. Nat. Struct. Biol. 2003;
10:349-56.
50* Bencharit S, Morton CL, Howard-Williams EL, Danks MK, Potter PM, Redinbo MR. Structural
insights into CPT-11 activation by mammalian carboxylesterases. Nat. Struct. Biol. 2002;9:337-42.
51* Bencharit S, Chumderpadetsuk R, Phankosol P. Shock-Absorbing Behavior Concept of
Osseointegrated Implant Prosthesis. Chulalongkorn U. Dent. J. 1997;20:121-26.
52* Bencharit S, Phankosol P, Charoonpatrapong K, Pongrasamiroj L. Flexural Strength of
Autopolymerizing Acrylic Resin Tray Materials. Chulalongkorn U. Dent. J. 1995;18:199-207.
Sompop	
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  PhD,	
  FACP	
  
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Abstracts (*Refereed, #Award wining)
1* Bencharit S, Carlson J, Holder S, Byrd W, Dhungana S, Sumner S. Enhancing Biomarker
Discovery in Saliva by Depleting Salivary Amylase. International Association of Dental Research
2015, Boston, MA.
2* Holder S, Desai E, Bencharit S. Structural Analysis of Glycation in Hyperglycemia-associated
Serum Proteins. International Association of Dental Research 2015, Boston, MA.
3* Desai E, Holder S, Bencharit S. Molecular Analysis of Glycated Albumin. International
Association of Dental Research 2015, Boston, MA.
4* Martinez Luna AA, Byrd KM, Yu N, Bencharit S, Morelli T, Kim SJ, Offenbacher S, Barros SP.
Osteogenic Activity Associated With Porous Tantalum Implants in Diabetic Patients. International
Association of Dental Research 2015, Boston, MA.
5* Edelmann AR, Nguyen T, Tyndall DA, Preisser J, Hosseini B, Bencharit S. Evaluation of Implant
Position in Single Immediate Implant Placement Using Immediate Post-operative Cone-beam
Computer Tomography: An Exploratory Study. International Association of Dental Research 2015,
Boston, MA.
6* Edelmann AR, Baxter SS, Dibble CF, Byrd WC, Carlson J, Mack CR, Saldarriaga I, Bencharit S.
Systems Biology and Proteomic Analysis of Cerebral Cavernous Malformation. (Poster
Presentation) American Association of Dental Research 2014, Charlotte, NC.
7* Hosseini B, Byrd WC, Khan A, Bencharit S. Antibiotics and Immediate Implant Thearpy for Teeth
with Apical Pathology. (Oral Presentation) American Association of Dental Research 2014,
Charlotte, NC.
8* Mayo MV, Kohltfarber H, Border MB, Byrd WC, Buse JB, Offenbacher S, Baxter SB, Carlson J,
Bencharit S. Alteration in salivary proteomes associated with hemoglobin A1C changes in Type 1
and 2 Diabetes. Hinman Student Research Symposium 2013, Memphis, TN.
#The student presenter was selected as UNC representative.
9* Border MB, Schwartz S, Carlson J, Dibble CF, Ghannoum M, Webster-Cyriaque J, Bencharit S.
HIV-infected patients with oropharyngeal candidiasis and HIV-associated salivary gland disease:
A salivary proteomic analysis. The 3rd International Conference on Proteomics & Bioinformatics
2013, Philadelphia, PA.
#Won the Best Poster Award.
10* Bencharit S. Exploring protein biomarkers in saliva using a proteomic approach. The 3rd
International Conference on Proteomics & Bioinformatics 2013, Philadelphia, PA.
11* Byrd W, Border M, Barros S, Offenbacher S, Baxter SS, Carlson J, Bencharit S, Role of Salivary
Proteins in Candida-Associated Denture Stomatitis, International Association for Dental Research
2013, Seattle, WA.
12* Mayo MV, Kohltfarber H, Border M, Byrd W, Buse J, Offenbacher S, Baxter SS, Carlson J,
Bencharit S, A cross-sectional study of salivary proteomes and diabetes, International Association
for Dental Research 2013, Seattle, WA.
13* Edelmann A, Dibble CF, Carlson J, Byrd W, Mack CR, Bencharit S, in vitro Proteomic Changes
Associated with Cerebral Cavernous Malformations, International Association for Dental Research
2013, Seattle, WA.
14* Bencharit S, Full Mouth Rehabilitation for a Patient with Dentinogenesis Imperfecta. The Member
Speaker Forum Session, American College of Prosthodontists 2012, Baltimore, MD.
15* Bencharit S, Exploring salivary proteomes in oral and systemic diseases, 2nd Conference on
Proteomics & Bioinformatics 2012, Las Vegas, NV.
16* Border MB, Schwartz S, Carlson J, Kohltfarber H, Offenbacher S, Buse JB, Bencharit S, Salivary
Proteomics for Edentulous Patients with Type 2 Diabetes, 2nd International Conference on
Proteomics & Bioinformatics 2012, Las Vegas, NV.
Sompop	
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  DDS,	
  MS,	
  PhD,	
  FACP	
  
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17* Bencharit S, Schwartz S, Carlson J, Kohltfarber H, Mack CR, Tarran R, Redinbo MR. Role of
PLUNC in diabetes and oral disease. American Association of Dental Research 2012, Tampa, FL.
18* Mack CR, Dibble CF, Schwartz S, Carlson J, Bencharit S. Proteomic analysis for cerebral
cavernous malformations. American Association of Dental Research 2012, Tampa, FL.
19* Mayo MV, Kohltfarber H, Schwartz S, Carlson J, Bencharit S. Salivary proteomic profiling for
diabetes. American Association of Dental Research 2012, Tampa, FL.
20* Bencharit S, Givens E, Hosseini B, Mack CR. Role of perioperative antibiotics in replacing an
endodontically-treated tooth with a dental implant. Academy of Osseointegration 2012, Phoenix,
AZ.
21* Givens E, Bencharit S, Phillips C, Tyndall D. Immediate Placement and Provisionalization of
Implants Placed into Sites with Periradicular Infection: Influence of Antibiotics on Implant Survival
Rates (Table Clinic). American College of Prosthodontists 2011, Phoenix, AZ.
22* Bencharit S, Immediate Implant Therapy for A Failed Endodontically Treated Tooth: A Biological
and Clinical Perspective. The Member Speaker Forum Session, American College of
Prosthodontists 2011, Phoenix, AZ.
23* Barbaro CP, Givens E, Bencharit S, Tyndall D. Clinical outcomes of immediate placement and
loading of dental Implants replacing a tooth with with a periapical radiolucency without using
antibiotics (Table Clinic). American College of Prosthodontists 2011, Phoenix, AZ.
24* Bencharit S, Al-Tarawneh, Schwartz S, Border MB, Carlson J, Barros SP, Loewy Z, Offenbacher
S. Salivary proteomic analysis for candida-associated denture stomatitis. International Association
of Dental Research 2011, San Diego, CA.
25* Border MB, Schwartz S, Carlson J, Dibble CF, Ghannoum M, Webster-Cyriaque J, Bencharit S.
HIV-associated oropharyngeal candidiasis and salivary gland disease: Salivary Proteomics.
International Association of Dental Research 2011, San Diego, CA.
26* Bencharit S, Border MB, Wright JT. Full mouth rehabilitation with dental implants for a patient
with dentinogenesis imperfecta: a case report. Academy of Osseointegration, 2011, Washington
DC.
27* Border MB, Schwartz S, Carlson J, Kohltfarber H, Offenbacher S, Buse JB, Bencharit S. An
exploratory investigation of the diagnostic use of salivary biomarkers for type 2 diabetes in
edentulous patients (Table Clinic). American College of Prosthodontists 2010, Orlando, FL.
#Won the first-place Table Clinic Award in the pre-doctoral category.
28* Al-Tarawneh SK, Bencharit S. Schwartz S, Carlson J, Barros S, Loewy Z, Offenbacher S. Salivary
Proteomic Analysis of Candida-Associated Denture Stomatitis: An Exploratory Study(Table
Clinic). American College of Prosthodontists 2010, Orlando, FL.
29* Dibble CF, Bencharit S, Feinberg N, Olorvida MV, Borikova AL, and Johnson GL. LIM Kinase-
Cofilin signaling is dysregulated in Cerebral Cavernous Malformation disease. 2010 CCM
Pathobiology 2010, Chevy Chase, MD.
30* Offenbacher S, Barros S, Bencharit S, Loewy Z, Gendreau L. Mucosal Gene Expression and
Salivary Proteomic Analysis of Candidiasis-Associated Denture Stomatitis. International
Association of Dental Research 2010 Barcelona, Spain.
31* Carlson J, Bencharit S, Altarawneh SK, Ross GF, Dibble CF, Barros S, Loewe Z, Offenbacher S,
Schwartz S. Leveraging Parallel Mass Spectrometry Platforms to Identify Biomarker Signatures of
Oropharyngeal Candidiasis in Patient Saliva. American Society of Mass Spectrometry Annual
Conference 2010, Minneapolis, MN.
32* Al-Tarawneh SK, Bencharit S. Proteomic Analysis and Biomarker Discovery of Human Saliva-A
Systematic Review. American Association of Dental Research (AADR) Annual Meeting, March
2010, Washington DC.
33* Frazier-Bowers, S, Simmons D, Bencharit S. Novel Mutations in PTH1R cause Primary Failure of
Eruption. American Association of Dental Research (AADR) Annual Meeting, March 2010,
Washington DC.
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34* Hilder T, Malone M, Bencharit S, Colicelli J, Haystead T, Johnson G, and Wu C. (Poster
Presentation) Proteomic Identification of the Cerebral Cavernous Malformation Signaling
Complex. The Eighth International Symposium on Mass Spectrometry in the Health & Life
Sciences: Molecular & Cellular Proteomics 2008,University of California at San Francisco, San
Francisco, CA.
35* Malone MH, Bencharit S, Stalheim L, Sciaky N, Park K, Barbaro J, Johnson GL. (Poster
Presentation) The Cerebral Cavernous Malformations Proteins CCM1, CCM2, and CCM3 Form a
Ternary Complex and Are Required for Cardiovascular Function in Zebrafish. The 47th
Annual
Meeting-The American Society for Cell Biology 2007, Washington DC.
36* Tran LC, Barbaro J, Cooper LF, Bencharit S. (Poster Presentation) Role of NF-κB in osteoblastic
differentiation, an implication of diabetic inflammatory disorder in bone healing. 39th Annual John
B. Graham 2007, UNC School of Medicine, Chapel Hill, NC.
37* Bencharit S, Morton CL, Hyatt JL, Kuhn P , Danks MK, Potter PM, Redinbo MR. (Poster
Presentation). Structural Basis of Heroin and Cocaine Metabolism by Human Carboxylesterase I.
The 31st
Mid-Atlantic Crystallography Meeting, May 2003, Duke University, Durham, NC.
#Received the Paul Sigler Award for the best student’s poster.
38* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. (Poster Presentation).
The “Side Door” Proposal: Structure and Function of a Rabbit Liver Carboxylesterase. International
Association for Dental Research 2002, San Diego, CA.
# Hatton Award Research Competition
39* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. Cancer Drug Activation
by Liver Carboxylesterase (Poster Presentation). American Crystallographic Association Annual
Meeting, July 2001, Los Angles, CA. American Crystallographic Association, INC. 2001;80:630.
40* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. Cancer Drug Activation
by Carboxylesterase: A Structural Study (Poster Presentation). International Association for Dental
Research 2001, Chiba, Japan.
41* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. The Structural Basis of
Cancer Drug Activation by Carboxylesterases (Poster Presentation). The 29th Annual Mid-Atlantic
Protein Crystallography Meeting 2001, Williamsburg, VA.
42* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. Structural basis of cancer
drug activation by carboxylesterase (Poster Presentation) University of North Carolina, Chapel Hill,
School of Medicine: Structural Biology and Bioinformatics Conference 2001, Sheraton Chapel Hill
Hotel, Chapel Hill, NC.
43* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. Carboxylesterases and
their roles activation in camptothecin and other compounds (Poster Presentation). Triangle
Biophysic Symposium 2000, Durham, NC.
44* Bencharit S, Soobarb R, Anterior single-tooth implant restorations (Oral Presentation). The Dental
Association of Thailand 1999, Bangkok, Thailand.
45* Bencharit S, Schardt-Sacco D, Zuniga JR, Minsley GE. Surgical & Prosthodontic Rehabilitation for
A Patient with Florid Cemento-Osseous Dysplasia. American Academy of Maxillofacial Prosthetics
1999, Philadelphia PA.
46* Bencharit S, Soobarb R, Surgical and prosthodontic considerations for a anterior single-tooth
implant restorations (Table Clinic). American College of Prosthodontists Annual Meeting, October
1999, New York City. NY.
47* Bencharit S. An in vitro radiographic evaluation of peri-implant bone (Oral presentation for the
John J. Sharry Competitition) American College of Prosthodontists 1999, New York City, NY.
48* Bencharit S. A titanium custom abutment (Table Clinic). American College of Prosthodontists
Annual Meeting, October 1999, New York City, NY.
49* Bencharit S, Sooparb R. A retrievable cement-retained implant prosthesis (Table Clinic). American
College of Prosthodontists 1998, San Diego, CA
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50* Bencharit S, Tyndall DA. An in vitro evaluation of peri-implant bone defects using subtraction
radiography and tuned aperture computed tomography (Table Clinic). American College of
Prosthodontists 1998, San Diego, CA.
Invited Presentations
2015 Trabecular Metal Implants and Immediate Implant Surgery, Mahidol University, Bangkok,
Thailand
2015 Breakthrough Concepts in Dental Implant and Full-arch Immediate Loading Protocol, Zimmer
Dental, Pittsburgh, PA.
2015 Implant Update: Introduction to Immediate Implant Therapy, Raleigh-Wake County Dental
Society, Raleigh, NC.
2015 Trabecular Metal Implants, Best things next to bone? Triad Study Club,
Greensboro, NC
2015 Immediate Implant Therapy, Austim Implant Study Club, Leland, NC
2015 Implant Treatment Options for Edentulous Patients: REVITALIZE PATIENT
SOLUTIONS, Bend Implant Study Club, Bend, OR
2014 Common Failures and Complications in Implant Prosthodontics. Greensboro Dental Society,
Greensboro, NC.
2014 Anterior Guidance in Implant Dentistry, Zimmer Study Club, Pinehurst, NC.
2014 Immediate Implant Placement in a Case with Defective Buccal Alveolar Bone, Trabecular Metal
Summit, Zimmer Dental Inc, Carlsbad, CA
2014 Trabecular Metal Implants and Hybrid Prostheses, Navy Dental Prosthodontic Conference, San
Diego, CA
2014 Applications of structural biology to salivary protein biomarker discovery, Southeastern Center
for Integrated Metabolomics, University of Florida at Gainesville
2013 Development and Clinical Applications of Porous Tantalum Trabecular Metal enhanced Titanium
Dental Implants, Dr. Bruce Arne’s Implant, Wilmington, NC.
2013 Development and Clinical Applications of Porous Tantalum Trabecular Metal enhanced Titanium
Dental Implants, Zimmer Study Club, Pinehurst, NC.
2012 Biology of Saliva and Salivary Proteins, Forsyth County Dental Society, April 2012, Winston-
Salem, NC.
2012 Common Failures and Complications in Implant Prosthodontics. Dr. Bruce Arne’s Implant Study
Club 2012, Wilmington, NC.
2011 Biological and Clinical Aspects of Immediate Implant Therapy. Bruce Arne’s Implant Study Club
2011, Wilmington, NC.
Continuing Education Courses and Area Health Education Courses (AHEC)
2015 Trabecular Metal Implants and Immediate Implant Therapy
Zimmer Dental, Chiang Mai, Thailand
Zimmer Dental, Phuket, Thailand
2015 Cadaver-based Computer-aid Implant Planning and Guided Surgery Course, Zimmer
Dental, Parsippany, NJ
Matthew Wood Prosthodontics Symposium
Computer-aid treatment planning and guided surgical protocols
2014 UNC School of Dentistry
Update in Theories & Clinical Application of Dental Implants
2014 Dental Domain Corp, Quezon City, Philippines
2014 S31 Sukhumvit Hotel, Bangkok, Thailand
2014 JW Mariott Hotel, Medan, Indonesia
2014 Crowne Plaza Hotel, Jakarta, Indonesia
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Treatment Planning in Implant Prosthodontics
2014 Asheville, NC
Update in Theories & Clinical Application of Dental Implants
2014 Dental Domain Co
Introduction to Simplant and Guided Surgery
2013 Zimmer Institute, Parsippany, NJ
Theories, Techniques & Options for the Restoration of Dental Implants:
Lecture and Hands on Workshop
2013 Shanghai Fraternity Association HK – HONG KONG
2013 National Taiwan University Hospital – Taipei City, TAIWAN
2013 S31 Sukhumvit Hotel Bangkok, THAILAND
2013 Hilton Petaling Jaya Hotel, Kuala Lumpur, MALAYSIA
2013 Q&M Dental Centre – SINGAPORE
Intermediate/Advanced Surgical Dental Implant Therapy
2013 Zimmer Institute, Parsippany, NJ
Matthew Wood Prosthodontic Symposium:
Anterior Implant Placement and Restorations
UNC School of Dentistry
2013 Immediate Placement and Loading of a Single-Tooth Implant
Intermediate/Advanced Restorative Dental Implant Therapy
2013 Zimmer Institute, Carlsbad, CA.
Development and Clinical Applications of Porous Tantalum Trabecular
Metal enhanced Titanium Dental Implants
2013 Zimmer study club, Wilmington, NC
2013 Zimmer study club, Pinehurst, NC
Intermediate/Advanced Restorative Dental Implant Therapy
Matthew Wood Prosthodontic Symposium:
Immediate Placement and Loading of a Single-Tooth Implant
2012 UNC School of Dentistry
Immediate Implant Therapy
2012 Charlotte Area Health Education Center (CAHEC), Charlotte, N
Addressing Non-Healing Endodontic Cases: From Retreatment to Implant Placement
2012 UNC School of Dentistry
Basic/Intermediate Comprehensive Dental Implant Therapy
2012 Zimmer Institute Parsippany, NJ
2011 Zimmer Institute, Parsippany, NJ
Implant Therapy and Management for the Entire Dental Team
2012 UNC School of Dentistry
Implant-retained Overdentures: A Practical Approach for General Dentists
2011 Wake Area Health Education Center (WAHEC), Raleigh, NC
Last Chance CE: Single-tooth Implants for Restorative Dentists
2010 UNC-School of Dentistry, Chapel Hill, NC
Oral Rehabilitation with Dental Implants
2010 South East Area Health Education Center (SEAHEC), Wilmington, NC
2010 Southern Regional Area Health Education Center (SAHEC), Fayetteville, NC
Single-tooth Implant Restorations for General Dentists
2009 Eastern Area Health Education Center (EAHEC), Greenville, NC
2009 Wake Area Health Education Center (WAHEC), Raleigh, NC
2009 Southern Regional Area Health Education Center (SAHEC), Fayetteville, NC
Contemporary Implant Restorations
2009 Mountain Area Health Education Center (MAHEC), Ashville, NC
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2008 South East Area Health Education Center (SEAHEC), Wilmington, NC
2007 Charlotte Area Health Education Center (CAHEC), Charlotte, NC
2007 Mountain Area Health Education Center (MAHEC), Ashville, NC
2011 Southern Regional Area Health Education Center (SAHEC), Fayetteville, NC
2014 Mountain Area Health Education Center (MAHEC), Ashville, NC
2015 Charlotte Area Health Education Center (CAHEC), Charlotte, NC
Contemporary Maxillary Implant Restorations
2006 Eastern Area Health Education Center (EAHEC), Greenville, NC
TEACHING ACTIVITIES
Major Teaching Responsibilities (Courses)
2015- Course Faculty, DENT 489: Digital Dentistry, Giving lectures in the topic:
“Computer-aided Implant Planning and Guided Surgery”
2014- Course Faculty, PERIO 820: Dental Implants: an Introduction, Giving a lecture in the
topic: “Introduction to Zimmer Implant System”
2014- Course Faculty, DENT 320: Dental Implants, Giving lectures in the
topics: “Introduction to Immediate Implant Therapy”.
2014- Course Faculty, OBIO 720: Topics in Oral Biology, Giving a lecture in the topic:
“Salivary Biology and Saliva-based Diagnostics”
2014- Course Faculty, DENT 225: Removable Partial Prosthodontics II, Giving a lecture in the
topic: “Interim Acrylic Partial Dentures”
2010-2012 Course Faculty, DENT 225: Removable Partial Prosthodontics II
2008-2013 Course Director, OBIO 720: Advanced Topics in Oral Biology
2005-2010 Course Faculty, DENT 320: Dental Implants, Giving a lecture in the
topic: “Introduction to Contemporary Implant Restorations for Complete
Edentulism” and “Full mouth Rehabilitation with Dental Implants”
2005- Clinic Attending Faculty, DDS General Dentistry, Prosthodontic Clinics as well as
Graduate Prosthodontic Clinics
2005-2008 Course Faculty, PERI 820: Dental Implants: An Introduction”, Giving a
lecture in the topic: “Full Mouth Rehabilitation with Dental Implants”
2013-2014 Course Faculty DENT 204, Fixed Prosthodontics I
2008-2009 Course Faculty, DENT 212, Removable Prosthodontics I
2008-2009 Course Faculty, DENT 225, Removable Partial Prosthodontics II
2003-2005 Clinical Attending, DDS Diagnosis and Treatment Planning, Fixed, and Removable
Prosthodontic Clinics.
1999-2003 Teaching Assistant, Chemistry 131, Nucleic Acid Chemistry, Giving three lectures in the
topic: Structures of Protein-Nucleic Acid Complexes.
1996-1999 Clinical Attending, DDS Comprehensive Care, Fixed/Removable Prosthodontic Clinics.
1996-1999 Course Faculty, DENT 211, Fixed Prosthodontics II
1994-1995 Course Faculty, Complete Denture Lab I and II (Course No. 667212 and 667214)
1994-1995 Course Faculty, Crown & Bridge Lab I and II (Course No 667232 and 667334)
1994-1995 Course Faculty, Partial Denture Lab I and II (Course No 667222 and 667242)
1994-1995 Course Faculty, Dental Materials I and II (Course No 667241 and 667242)
1994-1995 Clinical Attending, DDS Prosthodontic Clinic I and II (Course No 3207401 and
3207502)
Undergraduate and Predoctoral (DDS) Research Projects Supervised
2012- Systems Biology and Proteomic Analysis for Cerebral Cavernous Malformation
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Alex Edelmann (DDS2)
2014 AADR presentation
2013 IADR presentation
One first-authored manuscript published
2012- Salivary Proteomics
Warren Byrd (DDS1)
2013 IADR presentation
Manuscripts Published including one student first-authored manuscript
2011-2012 Proteomic Analysis of Cerebral Cavernous Malformation
C. Russell Mack
2012 AADR presentation
Manuscript Published
2010-2013 Salivary Proteomics for Diabetes
M. Virginia Mayo (DDS2)
2013 Hinman conference (as UNC student representative)
2013 IADR presentation
2012 AADR presentation
2012 UNC DDS Summer Fellowship
Manuscript published
2010-2013 Salivary Proteomics for Oral and Systemic Diseases
Michael Border (Ohio State DDS4)
2010 Won first-place American College of Prosthodontists Table Clinic
2013 Won first-place the best poster award at the Proteomics 2013
Manuscripts published including one student first-authored manuscript
2007-2013 Immediate Implant Placement and Antibiotics
Colin Barbaro (DDS Class of 2013)
2011 American College of Prosthodontists Table Clinic Presentation
2009 and 2010 UNC DDS Summer Fellowship
Manuscript Published
2006-2011 Structure and Function of Programmed Cell Death 10
Justin Barbaro (DDS Class of 2011)
2006 UNC DDS Summer Fellowship
Manuscript Published
2005-2006 Structure and Function of Cerebral Cavernous Malformation Proteins
Duc Tung (DDS Class of 2009)
2005 UNC DDS Summer Fellowship
Theses Directed (Master Degree)
2009-2012 Immediate placement and loading of dental implants in infected sites and effects of
prophylactic antibiotics: an exploratory study
Edward Givens, Master Degree of Science in Prosthodontics
2012 American College of Prosthodontists, 3rd place John Sherry Research Competition
2011 American College of Prosthodontists Table Clinic Presentation
One student first-authored manuscript published
2008-2011 Proteomic analysis of saliva in patients with denture stomatitis
Sandra Al-Tarawneh, Master Degree of Science in Prosthodontics
Two student first-authored Manuscript Published
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Other Thesis and Predoctoral Research Committees
2006-2009 Modulation of Murine Bone Marrow-derived CFU-F and CFU-OB by
in vivo Bisphosphonate and Fluoride Treatment
Ming-Yi Chou, Master Degree of Science in Prosthodontics
Mentor: Dr. Lyndon Cooper
2005-2008 Study protein-protein interaction in methyl-directed DNA mismatch repair in E. coli:
Exonuclease I (Exo I) and DNA helicase II (UvrD); A minimal exonuclease domain of
WRN forms a hexamer on DNA prossesses both 3’-5’ exonuclease and 5’-protruding
strand endonuclease activities; and Solving the structure of the ligand-binding domain of
the pregnane-xenobiotic-receptor with 17β estradiol and T1317.
Yu Xue, Doctor of Philosophy in Chemistry
Mentor: Dr. Matt Redinbo
2002-2005 Dlx-3 in osteoblast differentiation.
Preeda Pungpapong, Master Degree of Science in Prosthodontics,
Mentor: Lyndon Cooper
GRANTS, CONTRACTS, AND PATENTS
Active
2015-2016
Product influence on morning mouth feel, salivary biomarkers, and histology of selected oral
surfaces
Principal investigator: Sompop Bencharit
Agency: Colgate
Type: Research Grant
Amount: total of $143,913
The aim of this proposal is to examine the changes in morning mouth feel, salivary biomarkers, and
histology of the oral mucosa based on different mouth rinses or tooth pastes use.
2014-2019
Role of IL-37 Genetic Variants in Modulating Innate Immune Response to Periodontal Pathogens
Principal investigator: Steven Offenbacher
Agency: National Institute of Dental and Craniofacial Research (NIDCR)
Type: Research Grant (R01)
Amount: $1,000,000 (direct)
The aim of this proposal is to understand the role of IL-37 genetic variations in periodontal disease
Role: Investigator
2013-2015
NMR and UPLC-MS Broad Spectrum Platforms for Salivary Metabolomics
Principal investigator: Sompop Bencharit (UNC), Suraj Dhungana (RTI)
Agency: North Carolina Translational and Clinical Sciences Institute (NCTRACS)
Type: NCTranCS pilot in collaboration with RTI
Amount: $10,000
The aim of this proposal is to develop methods for analysis human whole saliva using NMR and UPLC
MS based metabolomics.
2013-2015
Morning mouth feel and salivary biomarkers for dry mouth
Principal investigator: Sompop Bencharit
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Agency: Colgate
Type: Research grant
Amount: total of 64,459 (direct)
This study is interested in analyzing subject's saliva microbiomes and physiological responses associated
with heavy alcohol and tobacco uses.
2014-2015
University Educational Grant
Principal investigator: Sompop Bencharit
Agency: Zimmer Dental Inc
Type: Education grant
Period: 07/01/14 – 12/31/15
Amount: total of $4,000
This grant primarily supports the annual Matthew Wood Prosthodontic Symposium.
2012-2016
A molecular and cellular comparison of bone inductive properties of trabecular metal®
vs titanium among Healthy, diabetic , smoking and osteopenic subjects
Principal investigator: Steven Offenbacher
Agency: Zimmer Dental Inc
Type: Research grant
Period: 07/01/12 – 12/31/15
Amount: total of $386,654
This proposal aims to examine the molecular and cellular difference between conventional
titanium dental implants and trabecular metal implants.
Role: Co-PI
2012-2016
University Educational Grant
Principal investigator: Sompop Bencharit
Agency: Zimmer Dental Inc
Type: Education grant
Period: 05/01/12 – 02/30/16
Amount: total of ~$70,000 including continuing education, an implant fellow and 114 Implant
fixtures and components (per year). This grant primarily includes the financial support for
continuing education courses and educational products for graduate students.
Completed
2013-2014
University Educational Grant
Principal investigator: Sompop Bencharit
Agency: Zimmer Dental Inc
Type: Education grant
Period: 09/01/13 – 12/31/14
Amount: total of $4,000
This grant primarily supports the annual Matthew Wood Prosthodontic Symposium.
2013
Salivary proteomics for type 1 diabetes
Principal investigator: Sompop Bencharit
Agency: University of North Carolina at Chapel Hill
Type: Junior Faculty Development Award
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Period: 01/01/13 – 12/31/13
Amount: total of $6,000
The aim of this project is to define the correlation between salivary proteomic biomarkers and known
clinical markers including serum glucose, hemoglobin A1C and possible clinical symptoms.
2012-2013
Effectiveness of antibiotics in immediate placement and loading of dental implants, replacing a
failed endodontically-treated tooth with a chronic periapical lesion: A randomized controlled
clinical trial
Principal investigator: Sompop Bencharit
Agency: American Academy of Implant Dentistry (AAID) Research Foundation
Type: Research Grant
Amount: $25,000 total
The overall goal of this project is to examine the clinical effectiveness of peri-operative antibiotic
therapy for immediate implant placement and loading replacing a tooth with a periapical
infection.
2012
University Educational Grant
Principal investigator: Sompop Bencharit
Agency: Zimmer Dental Inc
Type: Education grant
Amount: total of $4,000
This grant primarily supports the annual Matthew Wood Prosthodontic Symposium.
2009-2012
Role of Programmed Cell Death 10 in p38 MAP kinase activation and PDK1 signaling
Principal investigator: Sompop Bencharit
Agency: National Heart, Lung, and Blood Institute (NHLBI)
Type: Research grant (R21), Grant No. 1R21HL092338-01
Amount: total (direct) $275,000
This study primarily involves the functional analysis of PDCD10 in p38 MAP kinase activation
and PDK1 signaling in endothelial cells.
2010-2011
University Educational Grant
Principal investigator: Sompop Bencharit
Agency: Zimmer Dental Inc
Type: Education grant
Period: 11/01/10 – 10/31/11
Amount: total of ~$50,000 including $20,000 and 114 Implant fixtures and components
This grant primarily include the financial support for an implant symposium and educational
products for graduate students
2011
Salivary proteomic analysis for diabetes
Principal investigator: Sompop Bencharit
Agency: North Carolina Translational and Clinical Sciences Institute (NCTRACS)
Type: Small research grant for a pilot study; Grant No. 10KR81002
Period: 01/01/2011-12/31/2011
Amount: $10,000
The aim of this proposal is to explore diabetes-related salivary protein biomarkers in patients
with type 2 diabetes
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2011
Immediate placement and loading of dental implants into infected sites with and without antibiotics
Principal investigator: Edward Givens, Jr.
Agency: American College of Prosthodontists (ACP)
Type: Mentored Research Fellowship Award
Period: 01/01/2011 – 12/31/2011
Amount: $6,000 total
The overall goal of this project is to examine the necessity and effectiveness of peri-operative
antibiotic therapy for immediate implant placement and loading replacing a tooth with a
periapical infection.
Role: Faculty Mentor
2009-2010
Salivary Proteomic Profiling for Biomarkers in Diabetes
Principal investigator: Heidi Kohltfarber
Agency: North Carolina Translational and Clinical Sciences Institute (NCTRACS)
Type: Small research grant for a pilot study, Grant no. 2KR80905
Period: 11/15/2009 – 11/14/2010
Amount: $2,000 total
The overall goal of this project is to explore the possibility of using SELDI-TOF/MS to define the
salivary proteomic profiles of Type I diabetic patients.
2009
Proteomic Analysis of Saliva in Patients with Denture Stomatitis: An Exploratory Study
Principal investigator: Sandra Al-Tarawneh
Agency: American College of Prosthodontists (ACP)
Type: Mentored Research Fellowship Award
Amount: $4,500 total
The overall goal of this project is to explore the possibility of using SELDI-TOF/MS to define the
salivary proteomic profiles of patients with and without denture stomatitis.
2009
Biomarker Validation for Candida-associated Denture Stomatitis (CADS)
Principle Investigator: Sompop Bencharit
Agency: GalaxoSmithKline (GSK)
Type: Research grant
Period: 10/01/09 – 12/31/09
Amount: total (direct) $87,500
This study aims to identify salivary biomarkers for candida-associated denture stomatis (CADS)
in patients with and without CADS using mass spectrometry-proteomic analyses.
2006-2008
Clinical Research Training in Oral Diseases for Future
Principal investigator: James Beck.
Agency: National Institute of Dental & Craniofacial Research (NIDCR)
Type: Training grant (T32)
Period: 07/01/06 – 06/30/08
Amount: $160,000 (total-salary/benefit support)
The program primarily focuses on training dentists in clinical research who are also enrolled in
advanced clinical education programs to prepare to become academicians who can function as
interactive scientists who have the ability to address the expanding opportunities in dental, oral
and craniofacial clinical research.
Role: Scholar
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2006-2007
Structural Analysis of Programmed Cell Death 10 (PDCD10)
Principal investigator: Sompop Bencharit
Agency: Faculty Creativity Fund, School of Dentistry, University of North Carolina-Chapel Hill
Type: Small Grant
Amount: $5,000 total
The overall goal of this project is to engineer a soluble version of PDCD10 that is able to use for
x-ray crystallographic and biophysical studies.
2005-2010
Structural Analysis of Cerebral Cavernous Malformations.
Principal investigator: Sompop Bencharit
Agency: School of Dentistry, University of North Carolina-Chapel Hill
Type: Faculty Startup Fund
Amount: $50,000 total
The overall goal of this project is to determine the structural and functional relationships
between two scaffolding proteins in cerebral cavernous malformations, OSM and Krit1.
2005-2007
Engineering Soluble Variants of Heteromeric G Protein Alpha Subunit for Structural
Studies
Principal investigator: Sompop Bencharit.
Agency: University Research Council, University of North Carolina-Chapel Hill
Type: Small Grant
Period: 05/01/05 – 04/30/07
Amount: $4,000 total
The overall goal of this project is to engineer a soluble version of heteromeric G protein alpha
subunit that is able to use for x-ray crystallographic and biophysical studies.
Role: PI
Pending
2016-2019
The biological effects of e-cigarette aerosol exposure on the oral cavity
Principal investigator: Sompop Bencharit
Agency: NIH
Type: Research Grant (R01)
Amount: $1,000,000 (direct)
The aim of this proposal is to examine the affect of e-cigarette aerosol exposure on salivary cytokines,
oral microbiome, epithelial cell micronucleation, and oral proteome/metabolome in order to aid
consumers in making more educated decisions about e-cigarette usage. This study also aims to
characterize the chemical constituents of e-cigarette aerosol and correlate it with clinical/biological
outcomes.
Patents
“Crystallized Mammalian Carboxylesterase Polypeptide and Screening Methods Employing.” Matthew
R. Redinbo, Sompop Bencharit, Escher L. Howard-Williams, Christopher L. Morton, Philip M. Potter.
U. S. Provisional Patent Application Serial Number 60/347,513. Filed April 22, 2002.
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PROFESSIONAL SERVICE
University of North Carolina at Chapel Hill
2011-2015 Committee, Faculty Development Committee, UNC-School of Dentistry
2010-2014 Committee, Department of Periodontology Faculty Search Committee
(For three different faculty positions)
2009-2012 Oral Biology PhD Admission Committee, UNC-School of Dentistry
2009-2011 Committee, UNC-School of Dentistry Dean Search Committee
2008-2013 North Carolina Dental Intern Permit Examiner, UNC-School of Dentistry
2008-2012 Advisory Committee for Associate Dean of Research, UNC-School of Dentistry
2001-2002 Graduate Student Representative in the Graduate Program Directors Meeting, UNC-
School of Dentistry, Chapel Hill, NC.
Peer Review Grants, Journals, Editorial Boards, and Editors
2013- Academic Editor, PLOS ONE
2011- Associate Editor, Regenerative Dentistry and Implant Therapy
2012- Executive Editor, Dentistry: Current Research
2014- Editorial Board Member, Scientific Reports
2014- Editorial Board: Journal of Prosthodontics
2012- Editorial Board and Reviewer, ISRN Structural Biology
2012- Editorial Board, International Journal of Clinical Pharmacology & Toxicology
2011- Editorial Board, Dentistry: Current Research
2011- Editorial Board, Journal of Anaplastology
2011- Editorial Board, Advances in Pharmacoepidemiology & Drug Safety
2010- Editorial Board, Journal of Pharmacogenomics & Pharmacoproteomics
2007- Editorial Board, The Open Dentistry Journal
2015 Ad Hoc Reviewer, Expert review of Molecular Diagnosis
2014 Ad Hoc Reviewer, Applied and Environmental Microbiology
2013 Ad Hoc Reviewer, Powder Technology
2012 Ad Hoc Reviewer, RSC Advances
2012 Ad Hoc Reviewer, MICS Publishing Group/Clinical Journals (>18 journals)
2012 Ad Hoc Reviewer, BMC Physiology
2011 Ad Hoc Reviewer, Clinical Vaccine and Immunology
2011 Ad Hoc Reviewer, Journal of Proteomics
2011 Ad Hoc Reviewer, Polymer Chemistry
2011 Ad Hoc Reviewer, Recent Patents on Biomarkers
2011- Ad Hoc Reviewer, International Journal of Medical Sciences
2011- Ad Hoc Reviewer, PLoS ONE
2011- Ad Hoc Reviewer, Journal of Oral Implantology
2011- Ad Hoc Reviewer, Molecular Biosystems
2010-2013 Ad Hoc Reviewer, Journal of Structural Biology and Systems Biology
2010-2013 Ad Hoc Reviewer, Journal of American Dental Association
2009- Ad Hoc Reviewer, International Journal of Oral and Maxillofacial Implants
2009- Ad Hoc Reviewer, Journal of Dental Education
2004 Ad Hoc Reviewer, Journal of Molecular Biology
Scientific Peer Review (International)
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2013 Study Section, Italian Ministry of Health-General Direction for Health and Biomedical
Research and Health Research Institutions
2011 Study Section, Romanian National Research Council
2010 Study Section, Italian Ministry of Health-Young Investigator Award
Other Professional Service
2014-2018 Secretary and Treasurer, Salivary Research Group (SRG), International Association of
Dental Research (IADR)
2012 Organizing Committee, 2nd Conference on Proteomics & Bioinformatics,
July 2012, Las Vegas, NV
2012 Poster Presentation Session Chair-Salivary Diagnostics, International
Association of Dental Research Meeting, San Diego, CA
2011 Table Clinic Judge, American College of Prosthodontists (ACP) Annual
Meeting, Scottsdale, AZ
2011 Oral Presentation Session Chair-Salivary Diagnostics, International
Association of Dental Research Meeting, San Diego, CA
2010 Reviewer, Poster presentation, American Dental Education Association Meeting
1995-1996 Committee and Secretary, Thai Dental Implant Society
1995-1996 Academic Committee, Thai Prosthodontic Society
1995 Organizing Committee, the 1st International Dental Implant Congress, Bangkok Thailand
1994 Organizing Committee, the Annual Meeting of the Dental Association of Thailand
1994 Organizing Committee, the 1st Thailand Dental Education Congress
Other Service and Engagement
1999-2003 UNC Tae Kwon Do Club: Advisor
1998-2000 UNC Badminton Club: Co-founder and Secretary
Society Memberships
2014- American Dental Association
2014- North Carolina Dental Society
2014- Southeastern Academy of Prosthodontics
2006- American Dental Education Association
2006- Angioma Alliance
2005- Academy of Osseointegration
2001- International Association of Dental Research
2001- American Association of Dental Research
2001- American Crystallography Association
1997- American College of Prosthodontists
1995- Thai Prosthodontic Society
1995- Thai Dental Implant Society
1994- The Dental Association of Thailand

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cv_unc_Aug2015

  • 1. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  1  of  19       CURRICULUM VITAE (8/2015) SOMPOP BENCHARIT, DDS, MS, PhD, FACP PERSONAL HISTORY Citizenship: USA Office Address: Tel: (919) 537-3961 Fax: (919) 537-3977 Rm 342 Brauer Hall, CB#7450 Department of Prosthodontics, School of Dentistry University of North Carolina at Chapel Hill Chapel Hill, NC 27599-3290 Email: Sompop_Bencharit@unc.edu Website: http://benchars.wix.com/prosth Home Address: 112 Westgreen Dr., Chapel Hill, NC 27516 EDUCATION Institution and Location Degree Date Conferred Major University of North Carolina Research Scholar 2008 Clinical Research at Chapel Hill School of Dentistry University of North Carolina Postdoctoral Fellow 2004 Structural Biology/ at Chapel Hill Prosthodontics Department of Chemistry University of North Carolina PhD 2003 Oral Biology at Chapel Hill School of Dentistry University of North Carolina MS 1999 Prosthodontics at Chapel Hill School of Dentistry University of North Carolina Certificate 1999 Prosthodontics at Chapel Hill School of Dentistry Chulalongkorn University Graduate 1996 Prosthodontics Bangkok, Thailand Diploma Chulalongkorn University DDS 1994 Dentistry Bangkok, Thailand
  • 2. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  2  of  19       Licensure and Certification 2005- North Carolina Dental Practice License (Instructor Privilege License #0030) 1994- Thailand Dental Practice License Specialty Certification 2009- Fellow, American College of Prosthodontists 2009- Diplomate, American Board of Prosthodontics PROFESSIONAL EXPERIENCE Academic Appointments 2012- Assistant Professor (tenure-track), Department of Prosthodontics, School of Dentistry, University of North Carolina 2012- Adjunct Assistant Professor, Department of Pharmacology, School of Medicine, University of North Carolina 2005-2012 Research Assistant Professor, Department of Prosthodontics, School of Dentistry, University of North Carolina 2005-2012 Adjunct Research Assistant Professor, Department of Pharmacology, School of Medicine, University of North Carolina 2003-2005 Postdoctoral Fellow/Clinical Instructor, Department of Chemistry and Department of Prosthodontics, University of North Carolina 2001-2003 PhD Candidate, Oral Biology, School of Dentistry, University of North Carolina Dissertation Title: “Structure and Function of Mammalian Carboxylesterases” 2000-2003 Research Assistant, Redinbo lab, Department of Chemistry, University of North Carolina 1999-2003 Graduate Student and Research Assistant, Oral Biology, School of Dentistry, University of North Carolina 1998-1999 Chief Resident, Graduate Prosthodontics, Department of Prosthodontics, School of Dentistry, University of North Carolina 1997-1999 Clinical and Laboratory Teaching Assistant, Department of Prosthodontics, School of Dentistry, University of North Carolina 1996-1999 Graduate Student, Department of Prosthodontics, School of Dentistry, University of North Carolina Thesis Title: “Radiographic Evaluation of Peri-implant Bone” 1994-1996 Lecturer, Chulalongkorn University, Bangkok, Thailand Hospital Appointment 2006- University of North Carolina Hospitals Private Practice 2005- University of North Carolina Dental Faculty Practice HONORS 2013 University of North Carolina Junior Faculty Award 2011-2012 North Carolina Translational and Clinical Sciences Institute (NCTraCS) Pilot Grant
  • 3. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  3  of  19       2009-2011 American Recovery and Reinvestment Act Grant 2006-2008 NIH Clinical Research Scholar Award (T32), UNC-School of Dentistry 2003 Paul Sigler Award, The Best Student Poster Award, The 31st Mid-Atlantic Crystallography Meeting, Duke University, Durham, NC 2002 Hatton Award Candidate (American section), American Association of Dental Research 2001 Travel Grant Award, American Crystallography Association Meeting, Los Angles, CA 1999 Second-place winner, John J. Sharry Research Competition, American College of Prosthodontists Annual Meeting, New York 1998 Procter and Gamble Research Fellowship in Complete Denture Prosthodontics, American College of Prosthodontists 1998-2003 “King Ananda Mahidol” Scholarship, under the royal patronage of HRH King Bhumipol of Thailand, the best graduate student in dentistry BIBLIOGRAPHY Journal Articles (*Refereed) 1* Barrero C, Bencharit S, Petrola F. Case Report: Screw-Retained Zirconia Implant Restoration. J Oral Implantol. (in press) 2* Bencharit S, Byrd W, Hosseini B. Immediate placement of a porous-tantalum, trabecular metal- enhanced titanium dental implant with demineralized bone matrix into a socket with deficient buccal bone: A clinical report. J Prosthet Dent 2015;113:262-9. 3* Hosseini B, Byrd W, Preisser JS, Khan A, Duggan D, Bencharit S. Effects of Antibiotics on Bone and Soft Tissue Healing Following Immediate Single-tooth Implant Placement into Sites with Apical Pathology. J Oral Implantol. (in press) 4* Byrd WC, Schwartz-Baxter S, Carlson J, Barros S, Offenbacher S, Bencharit S. Role of salivary and candidal proteins in denture stomatitis: an exploratory proteomic analysis. Mol Biosyst. 2014;10:2299-304. 5* Baxter SS, Dibble CF, Byrd WC, Carlson J, Mack CR, Bencharit S. Role of cytoskeletal proteins in cerebral cavernous malformation signaling pathways: a proteomic analysis. Mol Biosyst 2014; 10:1881-92. 6* Edelmann AR, Baxter SS, Dibble CF, Byrd WC, Carlson, Saldarriaga I, Bencharit S. Systems biology proteomic analysis of cerebral cavernous malformation. Exp Rev Proteomics 2014;11: 395-404. 7* Bencharit S, Border MB, Mack CR, Byrd WC, Wright JT. Full mouth rehabilitation for a patient with dentinogenesis imperfecta: A clinical report. J Oral Implantol 2014;40:593-600. 8* Frazier-Bowers, SA, Wright JT, Hendricks HM, Lee J, Long K, Dibble CF, Bencharit S. Novel mutations in PTH1R associated with primary failure of eruption and osteoarthritis. J Dent Res 2014;93:134-9. 9* Bencharit S, Border MB, Edelmann AR. Update in Research and Methods in Proteomics and Bioinformatics. Expert Rev Proteomics 2013;10:413-5. 10* Hobbs CA, Blanchard MG, Alijevic O, Tan CD, Kellenberger S, Bencharit S, Cao R, Kesimer M, Walton WG, Henderson AG, Redinbo MR, Stutts MJ, Tarran R. Identification of SPLUNC1's ENaC-Inhibitory Domain Yields Novel Strategies to Treat Sodium Hyperabsorption in Cystic Fibrosis Airway Cultures. Am J Physiol Lung Cell Mol Physiol. Am J Physiol Lung Cell Mol Physiol. 2013;305:L990-L1001. 11* Bencharit S, Baxter SS, Carlson J, Byrd WC, Mayo MV, Border MB, Kohltfarber H, Urrutia E, Howard-Williams EL, Offenbacher S, Wu MC, Buse JB. Salivary proteins associated with hyperglycemia in diabetes: a proteomic analysis. Mol Biosyst, 2013 9:2785-97.
  • 4. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  4  of  19       12* Garland EA, Walton WG, Coakley RD, Tan CD, Gilmore RC, Hobbs CA, Tripathy, Betts L, Clunes LA, Bencharit S, Stutts MJ, Redinbo MR, Tarran R. Molecular Basis for pH-Dependent Mucosal Dehydration in Cystic Fibrosis Airways. Proc Natl Acad Sci USA 2013:110:15973-8. 13* Givens E, Bencharit S, Byrd WC, Phillips C, Hosseini B, Tyndall D. Immediate placement and provisionalization of implants into sites with periradicular infection with and without antibiotics: An exploratory study. J Oral Implantol 2015;41:299-305. 14* Bencharit S, Byrd WC, Al-Tarawneh SK, Hosseini B, Leong A, Reside G, Morelli T, Offenbacher S. Development and applications of porous tantalum trabecular metal enhanced titanium dental implants. Clin Implant Dent Relat Res 2014;16:817-26. 15* Al-Tarawneh SK, Bencharit S, Barros S, Loewy Z, Gendreau L, Offenbacher S. Clinical and Histological Findings of Denture Stomatitis as Related to Intraoral Colonization Patterns of C. albicans, Salivary Flow and Dry Mouth. J Prosthodont. 2013:22;13–22. 16* Barros S, Al-Tarawneh SK, Bencharit S, Loewy Z, Gendreau L, Offenbacher S.Salivary Cytokines and levels in in denture stomatitis: an exploratory case-control study. Open J Stomatol 2012:2;326-333. 17* Bencharit S, Border MB. Where are we in the World of Proteomics and Bioinformatics? Expert Rev Proteomics 2012;9:489-91. 18 Bencharit S. The Discovery of Insulin and the Future for Insulin Replacement Therapy. Int J Clin Pharmacol Toxicol 2012;1:101. 19 Bencharit S. History of Progress and Challenges in Structural Biology. J Pharmacogenom Pharmacoproteomics 2012;S4:e001. doi 10.4172/2153-0645.S4-e001. 20 Bencharit S. Bacterial Resistance to Antibiotics and Implanted Medical Devices. Adv Pharmacoepidem Drug Safety 2012;1:e112. doi:10.4172/2167-1052.1000e112. 21 Bencharit S, Byrd WC. Oral and craniofacial stem cells: where we are in understanding molecular signaling and clinical applications. Stem Cells Oral Med 2012; 1-2. doi: 10.2478/scom-2012-0001. 22 Bencharit S. Challenges and Prospective Applications of Extra-oral Implants for Maxillofacial Rehabilitation. Anaplastology 2012;1:e103. doi: 10.4172/2161-1173.1000e103. 23 Bencharit S. Progresses and Challenges of Omics Studies and Their Impacts in Personalized Medicine. J Pharmacogenom Pharmacoproteomics 2012;3:e105. doi:10.4172/2153-0645.1000e105. 24* Bencharit S, Al-Tarawneh SK, Schwartz S, Carlson J, Ross GF, Border MB, Mack CR, Byrd WC, Dibble CF, Barros S, Loewy Z, Offenbacher S. Elucidating role of salivary proteins in denture stomatitis using proteomic approach. Mol Biosyst. 2012;8:3216-3223. 25* Hobbs C, Blanchard M, Kellenberger S, Bencharit S, Cao R, Kesimer M, Walton WG, Redinbo MR, Stutts MJ, Tarran R. Identification of SPLUNC1’s ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airways. FASEB J 2012;26:4348-59. 26* Border MB, Schwartz S, Carlson J, Kohltfarber H, Offenbacher S, Buse JB, Bencharit S. Exploring Salivary Proteomes in Edentulous Patients with Type 2 Diabetes. Mol Biosyst. 2012;8:1304-10. 27* Bencharit S, Howard-Williams EL, Mack CR. Recent Studies and Patents in Salivary Protein Biomarkers for Diabetes. Recent Patents Biomarkers. 2012;2:1-5. 28* Bencharit S, Misiek DJ, Simon LA, Malone-Trahey A. Comprehensive multidisciplinary approach for a patient with severe skeletal class III: A clinical report. J Oral Implantol. 2012;38:63-70. 29* Al-Tarawneh SK, Border MB, Dibble CF, Bencharit S. Defining salivary biomarkers using mass spectrometry-based Proteomics : a systematic review. OMICS 2011;15:353-61. 30* Barrero C, Border MB, Bencharit S. Fabrication of a maxillary implant-retained prosthesis using an existing subperiosteal implant: A clinical report. Open Dent. 2011;5:122-5. 31 Bencharit S. How Academic Dentistry will Emerge from this Economic Crisis? Dentistry 2011;1:e101. doi:10.4172/2161-1122.1000e101 32* Dibble CF, Horst JA, Malone MH, Park K, Temple B, Cheeseman H, Barbaro JR, Johnson GL, Bencharit S. Defining the functional domain of programmed cell death 10 through its interaction with phosphatidylinositol-3,4,5-trisphosphate. PLOS ONE 2010;5:e1174.
  • 5. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  5  of  19       33* Wang Z, Pan J, Wright JT, Bencharit S, Zhang S, Everett ET, Teixeira FB, Preisser JS. Putative stem cells in human dental pulp with irreversible pulpitis-an exploratory study. J. Endod. 2010;36:820-5. 34* Borikova AL, Dibble CF, Sciaky N, Welch CM, Abell AN, Bencharit S, Johnson GL. Rho kinase inhibition rescues the endothelial cell cerebral cavernous malformation phenotype. J Biol. Chem. 2010;285:11760-4. 35* Bencharit S, Schardt-Sacco D, Barbaro CP, Border MB. Early placement of dental implants in a patient with severe periodontitis: A Case Report. Open Dent J. 2010;4:165-71. 36* Bencharit S, Reside GJ, Howard-Williams EL. Complex prosthodontic treatment with dental implants for a patient with polymyalgia rheumatica: A clinical report. Int J Maxillofac Implants. 2010;25:1241-5. 37* Patel M, Bencharit S. Removable partial overdentures, an alternative to full mouth reconstruction: A Clinical Report. Open Dent J 2009;3:213-8. 39* Al-Tarawneh SK, Bencharit S. Applications of SELDI-TOF mass spectrometry in salivary proteomic analysis. Open Dent J 2009; 3:74-79. 39* Hilder TL, Malone MH, Bencharit S, Colicelli J, Haystead TA, Johnson GL, Wu CC. Proteomic Identification of the Cerebral Cavernous Malformation Signaling Complex. J. Proteome Res. 2007;6:4343-55. 40* Xue Y, Moore YB, Orans J, Peng L, Bencharit S, Kliewer SA, Redinbo MR. Crystal Structure of the PXR-Estradiol Complex Provides Insights into Endobiotic Recognition. Mol. Endocrinol. 2007:21;1028-38. 41* Bencharit S, Cui CB, Siddiqui A, Howard-Williams EL, Sondek J, Zuobi-Hasona, K, Aukhil I. Structural insights into fibronectin type III domain mediated signaling. J. Mol. Biol. 2007:367; 303-9. 42* Bencharit S. A young faculty member's perspective of academic prosthodontics. J. Prosthodont. 2007;16:417-8. 43* Bencharit S, Edwards CC, Morton CL, Howard-Williams EL, Kuhn P, Potter PM, Redinbo MR. Multisite promiscuity in the processing of endogeneous substrates by human carboxylesterase 1. J. Mol. Biol. 2006;363:201-14. 44* Fleming CD, Bencharit S, Edwards CC, Hyatt JL, Tsurkan L, Bai F, Fraga C, Morton CL, Howard- Williams EL, Potter PM, Redinbo MR. Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil. J. Mol. Biol. 2005;352:165-77. 45* Uhlik MT, Temple B, Bencharit S, Kimple A, Siderovski D, Johnson GL. Structural and Evolutionary Division of Phosphotyrosine Binding (PTB) Domains. J. Mol. Biol. 2005;345:1-20. 46* Bencharit S, Schardt-Sacco D, Zuniga JR, Minsley GE. Surgical and prosthodontic rehabilitation for a patient with aggressive florid cemento-osseous dysplasia: a case report. J. Prosthet. Dent. 2003;90:220-4. 47* Redinbo MR, Bencharit S, Potter PM. Human carboxylesterase 1: from drug metabolism to drug discovery. Biochem. Soc. Trans. 2003;31:620-24. 48* Bencharit S, Morton CL, Hyatt JL, Kuhn P, Danks MK, Potter PM, Redinbo MR. Crystal Structure of Human Carboxylesterase 1 Complexed with the Alzheimer’s Drug Tacrine: From Binding Promiscuity to Selective Inhibition. Chem. Biol. 2003;10:341-9. 49* Bencharit S, Morton CL, Xue Y, Potter PM, Redinbo MR. Structural Basis of Heroin and Cocaine Metabolism by a Promiscuous Human Drug-Processing Enzyme. Nat. Struct. Biol. 2003; 10:349-56. 50* Bencharit S, Morton CL, Howard-Williams EL, Danks MK, Potter PM, Redinbo MR. Structural insights into CPT-11 activation by mammalian carboxylesterases. Nat. Struct. Biol. 2002;9:337-42. 51* Bencharit S, Chumderpadetsuk R, Phankosol P. Shock-Absorbing Behavior Concept of Osseointegrated Implant Prosthesis. Chulalongkorn U. Dent. J. 1997;20:121-26. 52* Bencharit S, Phankosol P, Charoonpatrapong K, Pongrasamiroj L. Flexural Strength of Autopolymerizing Acrylic Resin Tray Materials. Chulalongkorn U. Dent. J. 1995;18:199-207.
  • 6. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  6  of  19       Abstracts (*Refereed, #Award wining) 1* Bencharit S, Carlson J, Holder S, Byrd W, Dhungana S, Sumner S. Enhancing Biomarker Discovery in Saliva by Depleting Salivary Amylase. International Association of Dental Research 2015, Boston, MA. 2* Holder S, Desai E, Bencharit S. Structural Analysis of Glycation in Hyperglycemia-associated Serum Proteins. International Association of Dental Research 2015, Boston, MA. 3* Desai E, Holder S, Bencharit S. Molecular Analysis of Glycated Albumin. International Association of Dental Research 2015, Boston, MA. 4* Martinez Luna AA, Byrd KM, Yu N, Bencharit S, Morelli T, Kim SJ, Offenbacher S, Barros SP. Osteogenic Activity Associated With Porous Tantalum Implants in Diabetic Patients. International Association of Dental Research 2015, Boston, MA. 5* Edelmann AR, Nguyen T, Tyndall DA, Preisser J, Hosseini B, Bencharit S. Evaluation of Implant Position in Single Immediate Implant Placement Using Immediate Post-operative Cone-beam Computer Tomography: An Exploratory Study. International Association of Dental Research 2015, Boston, MA. 6* Edelmann AR, Baxter SS, Dibble CF, Byrd WC, Carlson J, Mack CR, Saldarriaga I, Bencharit S. Systems Biology and Proteomic Analysis of Cerebral Cavernous Malformation. (Poster Presentation) American Association of Dental Research 2014, Charlotte, NC. 7* Hosseini B, Byrd WC, Khan A, Bencharit S. Antibiotics and Immediate Implant Thearpy for Teeth with Apical Pathology. (Oral Presentation) American Association of Dental Research 2014, Charlotte, NC. 8* Mayo MV, Kohltfarber H, Border MB, Byrd WC, Buse JB, Offenbacher S, Baxter SB, Carlson J, Bencharit S. Alteration in salivary proteomes associated with hemoglobin A1C changes in Type 1 and 2 Diabetes. Hinman Student Research Symposium 2013, Memphis, TN. #The student presenter was selected as UNC representative. 9* Border MB, Schwartz S, Carlson J, Dibble CF, Ghannoum M, Webster-Cyriaque J, Bencharit S. HIV-infected patients with oropharyngeal candidiasis and HIV-associated salivary gland disease: A salivary proteomic analysis. The 3rd International Conference on Proteomics & Bioinformatics 2013, Philadelphia, PA. #Won the Best Poster Award. 10* Bencharit S. Exploring protein biomarkers in saliva using a proteomic approach. The 3rd International Conference on Proteomics & Bioinformatics 2013, Philadelphia, PA. 11* Byrd W, Border M, Barros S, Offenbacher S, Baxter SS, Carlson J, Bencharit S, Role of Salivary Proteins in Candida-Associated Denture Stomatitis, International Association for Dental Research 2013, Seattle, WA. 12* Mayo MV, Kohltfarber H, Border M, Byrd W, Buse J, Offenbacher S, Baxter SS, Carlson J, Bencharit S, A cross-sectional study of salivary proteomes and diabetes, International Association for Dental Research 2013, Seattle, WA. 13* Edelmann A, Dibble CF, Carlson J, Byrd W, Mack CR, Bencharit S, in vitro Proteomic Changes Associated with Cerebral Cavernous Malformations, International Association for Dental Research 2013, Seattle, WA. 14* Bencharit S, Full Mouth Rehabilitation for a Patient with Dentinogenesis Imperfecta. The Member Speaker Forum Session, American College of Prosthodontists 2012, Baltimore, MD. 15* Bencharit S, Exploring salivary proteomes in oral and systemic diseases, 2nd Conference on Proteomics & Bioinformatics 2012, Las Vegas, NV. 16* Border MB, Schwartz S, Carlson J, Kohltfarber H, Offenbacher S, Buse JB, Bencharit S, Salivary Proteomics for Edentulous Patients with Type 2 Diabetes, 2nd International Conference on Proteomics & Bioinformatics 2012, Las Vegas, NV.
  • 7. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  7  of  19       17* Bencharit S, Schwartz S, Carlson J, Kohltfarber H, Mack CR, Tarran R, Redinbo MR. Role of PLUNC in diabetes and oral disease. American Association of Dental Research 2012, Tampa, FL. 18* Mack CR, Dibble CF, Schwartz S, Carlson J, Bencharit S. Proteomic analysis for cerebral cavernous malformations. American Association of Dental Research 2012, Tampa, FL. 19* Mayo MV, Kohltfarber H, Schwartz S, Carlson J, Bencharit S. Salivary proteomic profiling for diabetes. American Association of Dental Research 2012, Tampa, FL. 20* Bencharit S, Givens E, Hosseini B, Mack CR. Role of perioperative antibiotics in replacing an endodontically-treated tooth with a dental implant. Academy of Osseointegration 2012, Phoenix, AZ. 21* Givens E, Bencharit S, Phillips C, Tyndall D. Immediate Placement and Provisionalization of Implants Placed into Sites with Periradicular Infection: Influence of Antibiotics on Implant Survival Rates (Table Clinic). American College of Prosthodontists 2011, Phoenix, AZ. 22* Bencharit S, Immediate Implant Therapy for A Failed Endodontically Treated Tooth: A Biological and Clinical Perspective. The Member Speaker Forum Session, American College of Prosthodontists 2011, Phoenix, AZ. 23* Barbaro CP, Givens E, Bencharit S, Tyndall D. Clinical outcomes of immediate placement and loading of dental Implants replacing a tooth with with a periapical radiolucency without using antibiotics (Table Clinic). American College of Prosthodontists 2011, Phoenix, AZ. 24* Bencharit S, Al-Tarawneh, Schwartz S, Border MB, Carlson J, Barros SP, Loewy Z, Offenbacher S. Salivary proteomic analysis for candida-associated denture stomatitis. International Association of Dental Research 2011, San Diego, CA. 25* Border MB, Schwartz S, Carlson J, Dibble CF, Ghannoum M, Webster-Cyriaque J, Bencharit S. HIV-associated oropharyngeal candidiasis and salivary gland disease: Salivary Proteomics. International Association of Dental Research 2011, San Diego, CA. 26* Bencharit S, Border MB, Wright JT. Full mouth rehabilitation with dental implants for a patient with dentinogenesis imperfecta: a case report. Academy of Osseointegration, 2011, Washington DC. 27* Border MB, Schwartz S, Carlson J, Kohltfarber H, Offenbacher S, Buse JB, Bencharit S. An exploratory investigation of the diagnostic use of salivary biomarkers for type 2 diabetes in edentulous patients (Table Clinic). American College of Prosthodontists 2010, Orlando, FL. #Won the first-place Table Clinic Award in the pre-doctoral category. 28* Al-Tarawneh SK, Bencharit S. Schwartz S, Carlson J, Barros S, Loewy Z, Offenbacher S. Salivary Proteomic Analysis of Candida-Associated Denture Stomatitis: An Exploratory Study(Table Clinic). American College of Prosthodontists 2010, Orlando, FL. 29* Dibble CF, Bencharit S, Feinberg N, Olorvida MV, Borikova AL, and Johnson GL. LIM Kinase- Cofilin signaling is dysregulated in Cerebral Cavernous Malformation disease. 2010 CCM Pathobiology 2010, Chevy Chase, MD. 30* Offenbacher S, Barros S, Bencharit S, Loewy Z, Gendreau L. Mucosal Gene Expression and Salivary Proteomic Analysis of Candidiasis-Associated Denture Stomatitis. International Association of Dental Research 2010 Barcelona, Spain. 31* Carlson J, Bencharit S, Altarawneh SK, Ross GF, Dibble CF, Barros S, Loewe Z, Offenbacher S, Schwartz S. Leveraging Parallel Mass Spectrometry Platforms to Identify Biomarker Signatures of Oropharyngeal Candidiasis in Patient Saliva. American Society of Mass Spectrometry Annual Conference 2010, Minneapolis, MN. 32* Al-Tarawneh SK, Bencharit S. Proteomic Analysis and Biomarker Discovery of Human Saliva-A Systematic Review. American Association of Dental Research (AADR) Annual Meeting, March 2010, Washington DC. 33* Frazier-Bowers, S, Simmons D, Bencharit S. Novel Mutations in PTH1R cause Primary Failure of Eruption. American Association of Dental Research (AADR) Annual Meeting, March 2010, Washington DC.
  • 8. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  8  of  19       34* Hilder T, Malone M, Bencharit S, Colicelli J, Haystead T, Johnson G, and Wu C. (Poster Presentation) Proteomic Identification of the Cerebral Cavernous Malformation Signaling Complex. The Eighth International Symposium on Mass Spectrometry in the Health & Life Sciences: Molecular & Cellular Proteomics 2008,University of California at San Francisco, San Francisco, CA. 35* Malone MH, Bencharit S, Stalheim L, Sciaky N, Park K, Barbaro J, Johnson GL. (Poster Presentation) The Cerebral Cavernous Malformations Proteins CCM1, CCM2, and CCM3 Form a Ternary Complex and Are Required for Cardiovascular Function in Zebrafish. The 47th Annual Meeting-The American Society for Cell Biology 2007, Washington DC. 36* Tran LC, Barbaro J, Cooper LF, Bencharit S. (Poster Presentation) Role of NF-κB in osteoblastic differentiation, an implication of diabetic inflammatory disorder in bone healing. 39th Annual John B. Graham 2007, UNC School of Medicine, Chapel Hill, NC. 37* Bencharit S, Morton CL, Hyatt JL, Kuhn P , Danks MK, Potter PM, Redinbo MR. (Poster Presentation). Structural Basis of Heroin and Cocaine Metabolism by Human Carboxylesterase I. The 31st Mid-Atlantic Crystallography Meeting, May 2003, Duke University, Durham, NC. #Received the Paul Sigler Award for the best student’s poster. 38* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. (Poster Presentation). The “Side Door” Proposal: Structure and Function of a Rabbit Liver Carboxylesterase. International Association for Dental Research 2002, San Diego, CA. # Hatton Award Research Competition 39* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. Cancer Drug Activation by Liver Carboxylesterase (Poster Presentation). American Crystallographic Association Annual Meeting, July 2001, Los Angles, CA. American Crystallographic Association, INC. 2001;80:630. 40* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. Cancer Drug Activation by Carboxylesterase: A Structural Study (Poster Presentation). International Association for Dental Research 2001, Chiba, Japan. 41* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. The Structural Basis of Cancer Drug Activation by Carboxylesterases (Poster Presentation). The 29th Annual Mid-Atlantic Protein Crystallography Meeting 2001, Williamsburg, VA. 42* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. Structural basis of cancer drug activation by carboxylesterase (Poster Presentation) University of North Carolina, Chapel Hill, School of Medicine: Structural Biology and Bioinformatics Conference 2001, Sheraton Chapel Hill Hotel, Chapel Hill, NC. 43* Bencharit S, Howard-Williams EL, Morton CL, Potter PM, Redinbo MR. Carboxylesterases and their roles activation in camptothecin and other compounds (Poster Presentation). Triangle Biophysic Symposium 2000, Durham, NC. 44* Bencharit S, Soobarb R, Anterior single-tooth implant restorations (Oral Presentation). The Dental Association of Thailand 1999, Bangkok, Thailand. 45* Bencharit S, Schardt-Sacco D, Zuniga JR, Minsley GE. Surgical & Prosthodontic Rehabilitation for A Patient with Florid Cemento-Osseous Dysplasia. American Academy of Maxillofacial Prosthetics 1999, Philadelphia PA. 46* Bencharit S, Soobarb R, Surgical and prosthodontic considerations for a anterior single-tooth implant restorations (Table Clinic). American College of Prosthodontists Annual Meeting, October 1999, New York City. NY. 47* Bencharit S. An in vitro radiographic evaluation of peri-implant bone (Oral presentation for the John J. Sharry Competitition) American College of Prosthodontists 1999, New York City, NY. 48* Bencharit S. A titanium custom abutment (Table Clinic). American College of Prosthodontists Annual Meeting, October 1999, New York City, NY. 49* Bencharit S, Sooparb R. A retrievable cement-retained implant prosthesis (Table Clinic). American College of Prosthodontists 1998, San Diego, CA
  • 9. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  9  of  19       50* Bencharit S, Tyndall DA. An in vitro evaluation of peri-implant bone defects using subtraction radiography and tuned aperture computed tomography (Table Clinic). American College of Prosthodontists 1998, San Diego, CA. Invited Presentations 2015 Trabecular Metal Implants and Immediate Implant Surgery, Mahidol University, Bangkok, Thailand 2015 Breakthrough Concepts in Dental Implant and Full-arch Immediate Loading Protocol, Zimmer Dental, Pittsburgh, PA. 2015 Implant Update: Introduction to Immediate Implant Therapy, Raleigh-Wake County Dental Society, Raleigh, NC. 2015 Trabecular Metal Implants, Best things next to bone? Triad Study Club, Greensboro, NC 2015 Immediate Implant Therapy, Austim Implant Study Club, Leland, NC 2015 Implant Treatment Options for Edentulous Patients: REVITALIZE PATIENT SOLUTIONS, Bend Implant Study Club, Bend, OR 2014 Common Failures and Complications in Implant Prosthodontics. Greensboro Dental Society, Greensboro, NC. 2014 Anterior Guidance in Implant Dentistry, Zimmer Study Club, Pinehurst, NC. 2014 Immediate Implant Placement in a Case with Defective Buccal Alveolar Bone, Trabecular Metal Summit, Zimmer Dental Inc, Carlsbad, CA 2014 Trabecular Metal Implants and Hybrid Prostheses, Navy Dental Prosthodontic Conference, San Diego, CA 2014 Applications of structural biology to salivary protein biomarker discovery, Southeastern Center for Integrated Metabolomics, University of Florida at Gainesville 2013 Development and Clinical Applications of Porous Tantalum Trabecular Metal enhanced Titanium Dental Implants, Dr. Bruce Arne’s Implant, Wilmington, NC. 2013 Development and Clinical Applications of Porous Tantalum Trabecular Metal enhanced Titanium Dental Implants, Zimmer Study Club, Pinehurst, NC. 2012 Biology of Saliva and Salivary Proteins, Forsyth County Dental Society, April 2012, Winston- Salem, NC. 2012 Common Failures and Complications in Implant Prosthodontics. Dr. Bruce Arne’s Implant Study Club 2012, Wilmington, NC. 2011 Biological and Clinical Aspects of Immediate Implant Therapy. Bruce Arne’s Implant Study Club 2011, Wilmington, NC. Continuing Education Courses and Area Health Education Courses (AHEC) 2015 Trabecular Metal Implants and Immediate Implant Therapy Zimmer Dental, Chiang Mai, Thailand Zimmer Dental, Phuket, Thailand 2015 Cadaver-based Computer-aid Implant Planning and Guided Surgery Course, Zimmer Dental, Parsippany, NJ Matthew Wood Prosthodontics Symposium Computer-aid treatment planning and guided surgical protocols 2014 UNC School of Dentistry Update in Theories & Clinical Application of Dental Implants 2014 Dental Domain Corp, Quezon City, Philippines 2014 S31 Sukhumvit Hotel, Bangkok, Thailand 2014 JW Mariott Hotel, Medan, Indonesia 2014 Crowne Plaza Hotel, Jakarta, Indonesia
  • 10. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  10  of  19       Treatment Planning in Implant Prosthodontics 2014 Asheville, NC Update in Theories & Clinical Application of Dental Implants 2014 Dental Domain Co Introduction to Simplant and Guided Surgery 2013 Zimmer Institute, Parsippany, NJ Theories, Techniques & Options for the Restoration of Dental Implants: Lecture and Hands on Workshop 2013 Shanghai Fraternity Association HK – HONG KONG 2013 National Taiwan University Hospital – Taipei City, TAIWAN 2013 S31 Sukhumvit Hotel Bangkok, THAILAND 2013 Hilton Petaling Jaya Hotel, Kuala Lumpur, MALAYSIA 2013 Q&M Dental Centre – SINGAPORE Intermediate/Advanced Surgical Dental Implant Therapy 2013 Zimmer Institute, Parsippany, NJ Matthew Wood Prosthodontic Symposium: Anterior Implant Placement and Restorations UNC School of Dentistry 2013 Immediate Placement and Loading of a Single-Tooth Implant Intermediate/Advanced Restorative Dental Implant Therapy 2013 Zimmer Institute, Carlsbad, CA. Development and Clinical Applications of Porous Tantalum Trabecular Metal enhanced Titanium Dental Implants 2013 Zimmer study club, Wilmington, NC 2013 Zimmer study club, Pinehurst, NC Intermediate/Advanced Restorative Dental Implant Therapy Matthew Wood Prosthodontic Symposium: Immediate Placement and Loading of a Single-Tooth Implant 2012 UNC School of Dentistry Immediate Implant Therapy 2012 Charlotte Area Health Education Center (CAHEC), Charlotte, N Addressing Non-Healing Endodontic Cases: From Retreatment to Implant Placement 2012 UNC School of Dentistry Basic/Intermediate Comprehensive Dental Implant Therapy 2012 Zimmer Institute Parsippany, NJ 2011 Zimmer Institute, Parsippany, NJ Implant Therapy and Management for the Entire Dental Team 2012 UNC School of Dentistry Implant-retained Overdentures: A Practical Approach for General Dentists 2011 Wake Area Health Education Center (WAHEC), Raleigh, NC Last Chance CE: Single-tooth Implants for Restorative Dentists 2010 UNC-School of Dentistry, Chapel Hill, NC Oral Rehabilitation with Dental Implants 2010 South East Area Health Education Center (SEAHEC), Wilmington, NC 2010 Southern Regional Area Health Education Center (SAHEC), Fayetteville, NC Single-tooth Implant Restorations for General Dentists 2009 Eastern Area Health Education Center (EAHEC), Greenville, NC 2009 Wake Area Health Education Center (WAHEC), Raleigh, NC 2009 Southern Regional Area Health Education Center (SAHEC), Fayetteville, NC Contemporary Implant Restorations 2009 Mountain Area Health Education Center (MAHEC), Ashville, NC
  • 11. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  11  of  19       2008 South East Area Health Education Center (SEAHEC), Wilmington, NC 2007 Charlotte Area Health Education Center (CAHEC), Charlotte, NC 2007 Mountain Area Health Education Center (MAHEC), Ashville, NC 2011 Southern Regional Area Health Education Center (SAHEC), Fayetteville, NC 2014 Mountain Area Health Education Center (MAHEC), Ashville, NC 2015 Charlotte Area Health Education Center (CAHEC), Charlotte, NC Contemporary Maxillary Implant Restorations 2006 Eastern Area Health Education Center (EAHEC), Greenville, NC TEACHING ACTIVITIES Major Teaching Responsibilities (Courses) 2015- Course Faculty, DENT 489: Digital Dentistry, Giving lectures in the topic: “Computer-aided Implant Planning and Guided Surgery” 2014- Course Faculty, PERIO 820: Dental Implants: an Introduction, Giving a lecture in the topic: “Introduction to Zimmer Implant System” 2014- Course Faculty, DENT 320: Dental Implants, Giving lectures in the topics: “Introduction to Immediate Implant Therapy”. 2014- Course Faculty, OBIO 720: Topics in Oral Biology, Giving a lecture in the topic: “Salivary Biology and Saliva-based Diagnostics” 2014- Course Faculty, DENT 225: Removable Partial Prosthodontics II, Giving a lecture in the topic: “Interim Acrylic Partial Dentures” 2010-2012 Course Faculty, DENT 225: Removable Partial Prosthodontics II 2008-2013 Course Director, OBIO 720: Advanced Topics in Oral Biology 2005-2010 Course Faculty, DENT 320: Dental Implants, Giving a lecture in the topic: “Introduction to Contemporary Implant Restorations for Complete Edentulism” and “Full mouth Rehabilitation with Dental Implants” 2005- Clinic Attending Faculty, DDS General Dentistry, Prosthodontic Clinics as well as Graduate Prosthodontic Clinics 2005-2008 Course Faculty, PERI 820: Dental Implants: An Introduction”, Giving a lecture in the topic: “Full Mouth Rehabilitation with Dental Implants” 2013-2014 Course Faculty DENT 204, Fixed Prosthodontics I 2008-2009 Course Faculty, DENT 212, Removable Prosthodontics I 2008-2009 Course Faculty, DENT 225, Removable Partial Prosthodontics II 2003-2005 Clinical Attending, DDS Diagnosis and Treatment Planning, Fixed, and Removable Prosthodontic Clinics. 1999-2003 Teaching Assistant, Chemistry 131, Nucleic Acid Chemistry, Giving three lectures in the topic: Structures of Protein-Nucleic Acid Complexes. 1996-1999 Clinical Attending, DDS Comprehensive Care, Fixed/Removable Prosthodontic Clinics. 1996-1999 Course Faculty, DENT 211, Fixed Prosthodontics II 1994-1995 Course Faculty, Complete Denture Lab I and II (Course No. 667212 and 667214) 1994-1995 Course Faculty, Crown & Bridge Lab I and II (Course No 667232 and 667334) 1994-1995 Course Faculty, Partial Denture Lab I and II (Course No 667222 and 667242) 1994-1995 Course Faculty, Dental Materials I and II (Course No 667241 and 667242) 1994-1995 Clinical Attending, DDS Prosthodontic Clinic I and II (Course No 3207401 and 3207502) Undergraduate and Predoctoral (DDS) Research Projects Supervised 2012- Systems Biology and Proteomic Analysis for Cerebral Cavernous Malformation
  • 12. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  12  of  19       Alex Edelmann (DDS2) 2014 AADR presentation 2013 IADR presentation One first-authored manuscript published 2012- Salivary Proteomics Warren Byrd (DDS1) 2013 IADR presentation Manuscripts Published including one student first-authored manuscript 2011-2012 Proteomic Analysis of Cerebral Cavernous Malformation C. Russell Mack 2012 AADR presentation Manuscript Published 2010-2013 Salivary Proteomics for Diabetes M. Virginia Mayo (DDS2) 2013 Hinman conference (as UNC student representative) 2013 IADR presentation 2012 AADR presentation 2012 UNC DDS Summer Fellowship Manuscript published 2010-2013 Salivary Proteomics for Oral and Systemic Diseases Michael Border (Ohio State DDS4) 2010 Won first-place American College of Prosthodontists Table Clinic 2013 Won first-place the best poster award at the Proteomics 2013 Manuscripts published including one student first-authored manuscript 2007-2013 Immediate Implant Placement and Antibiotics Colin Barbaro (DDS Class of 2013) 2011 American College of Prosthodontists Table Clinic Presentation 2009 and 2010 UNC DDS Summer Fellowship Manuscript Published 2006-2011 Structure and Function of Programmed Cell Death 10 Justin Barbaro (DDS Class of 2011) 2006 UNC DDS Summer Fellowship Manuscript Published 2005-2006 Structure and Function of Cerebral Cavernous Malformation Proteins Duc Tung (DDS Class of 2009) 2005 UNC DDS Summer Fellowship Theses Directed (Master Degree) 2009-2012 Immediate placement and loading of dental implants in infected sites and effects of prophylactic antibiotics: an exploratory study Edward Givens, Master Degree of Science in Prosthodontics 2012 American College of Prosthodontists, 3rd place John Sherry Research Competition 2011 American College of Prosthodontists Table Clinic Presentation One student first-authored manuscript published 2008-2011 Proteomic analysis of saliva in patients with denture stomatitis Sandra Al-Tarawneh, Master Degree of Science in Prosthodontics Two student first-authored Manuscript Published
  • 13. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  13  of  19       Other Thesis and Predoctoral Research Committees 2006-2009 Modulation of Murine Bone Marrow-derived CFU-F and CFU-OB by in vivo Bisphosphonate and Fluoride Treatment Ming-Yi Chou, Master Degree of Science in Prosthodontics Mentor: Dr. Lyndon Cooper 2005-2008 Study protein-protein interaction in methyl-directed DNA mismatch repair in E. coli: Exonuclease I (Exo I) and DNA helicase II (UvrD); A minimal exonuclease domain of WRN forms a hexamer on DNA prossesses both 3’-5’ exonuclease and 5’-protruding strand endonuclease activities; and Solving the structure of the ligand-binding domain of the pregnane-xenobiotic-receptor with 17β estradiol and T1317. Yu Xue, Doctor of Philosophy in Chemistry Mentor: Dr. Matt Redinbo 2002-2005 Dlx-3 in osteoblast differentiation. Preeda Pungpapong, Master Degree of Science in Prosthodontics, Mentor: Lyndon Cooper GRANTS, CONTRACTS, AND PATENTS Active 2015-2016 Product influence on morning mouth feel, salivary biomarkers, and histology of selected oral surfaces Principal investigator: Sompop Bencharit Agency: Colgate Type: Research Grant Amount: total of $143,913 The aim of this proposal is to examine the changes in morning mouth feel, salivary biomarkers, and histology of the oral mucosa based on different mouth rinses or tooth pastes use. 2014-2019 Role of IL-37 Genetic Variants in Modulating Innate Immune Response to Periodontal Pathogens Principal investigator: Steven Offenbacher Agency: National Institute of Dental and Craniofacial Research (NIDCR) Type: Research Grant (R01) Amount: $1,000,000 (direct) The aim of this proposal is to understand the role of IL-37 genetic variations in periodontal disease Role: Investigator 2013-2015 NMR and UPLC-MS Broad Spectrum Platforms for Salivary Metabolomics Principal investigator: Sompop Bencharit (UNC), Suraj Dhungana (RTI) Agency: North Carolina Translational and Clinical Sciences Institute (NCTRACS) Type: NCTranCS pilot in collaboration with RTI Amount: $10,000 The aim of this proposal is to develop methods for analysis human whole saliva using NMR and UPLC MS based metabolomics. 2013-2015 Morning mouth feel and salivary biomarkers for dry mouth Principal investigator: Sompop Bencharit
  • 14. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  14  of  19       Agency: Colgate Type: Research grant Amount: total of 64,459 (direct) This study is interested in analyzing subject's saliva microbiomes and physiological responses associated with heavy alcohol and tobacco uses. 2014-2015 University Educational Grant Principal investigator: Sompop Bencharit Agency: Zimmer Dental Inc Type: Education grant Period: 07/01/14 – 12/31/15 Amount: total of $4,000 This grant primarily supports the annual Matthew Wood Prosthodontic Symposium. 2012-2016 A molecular and cellular comparison of bone inductive properties of trabecular metal® vs titanium among Healthy, diabetic , smoking and osteopenic subjects Principal investigator: Steven Offenbacher Agency: Zimmer Dental Inc Type: Research grant Period: 07/01/12 – 12/31/15 Amount: total of $386,654 This proposal aims to examine the molecular and cellular difference between conventional titanium dental implants and trabecular metal implants. Role: Co-PI 2012-2016 University Educational Grant Principal investigator: Sompop Bencharit Agency: Zimmer Dental Inc Type: Education grant Period: 05/01/12 – 02/30/16 Amount: total of ~$70,000 including continuing education, an implant fellow and 114 Implant fixtures and components (per year). This grant primarily includes the financial support for continuing education courses and educational products for graduate students. Completed 2013-2014 University Educational Grant Principal investigator: Sompop Bencharit Agency: Zimmer Dental Inc Type: Education grant Period: 09/01/13 – 12/31/14 Amount: total of $4,000 This grant primarily supports the annual Matthew Wood Prosthodontic Symposium. 2013 Salivary proteomics for type 1 diabetes Principal investigator: Sompop Bencharit Agency: University of North Carolina at Chapel Hill Type: Junior Faculty Development Award
  • 15. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  15  of  19       Period: 01/01/13 – 12/31/13 Amount: total of $6,000 The aim of this project is to define the correlation between salivary proteomic biomarkers and known clinical markers including serum glucose, hemoglobin A1C and possible clinical symptoms. 2012-2013 Effectiveness of antibiotics in immediate placement and loading of dental implants, replacing a failed endodontically-treated tooth with a chronic periapical lesion: A randomized controlled clinical trial Principal investigator: Sompop Bencharit Agency: American Academy of Implant Dentistry (AAID) Research Foundation Type: Research Grant Amount: $25,000 total The overall goal of this project is to examine the clinical effectiveness of peri-operative antibiotic therapy for immediate implant placement and loading replacing a tooth with a periapical infection. 2012 University Educational Grant Principal investigator: Sompop Bencharit Agency: Zimmer Dental Inc Type: Education grant Amount: total of $4,000 This grant primarily supports the annual Matthew Wood Prosthodontic Symposium. 2009-2012 Role of Programmed Cell Death 10 in p38 MAP kinase activation and PDK1 signaling Principal investigator: Sompop Bencharit Agency: National Heart, Lung, and Blood Institute (NHLBI) Type: Research grant (R21), Grant No. 1R21HL092338-01 Amount: total (direct) $275,000 This study primarily involves the functional analysis of PDCD10 in p38 MAP kinase activation and PDK1 signaling in endothelial cells. 2010-2011 University Educational Grant Principal investigator: Sompop Bencharit Agency: Zimmer Dental Inc Type: Education grant Period: 11/01/10 – 10/31/11 Amount: total of ~$50,000 including $20,000 and 114 Implant fixtures and components This grant primarily include the financial support for an implant symposium and educational products for graduate students 2011 Salivary proteomic analysis for diabetes Principal investigator: Sompop Bencharit Agency: North Carolina Translational and Clinical Sciences Institute (NCTRACS) Type: Small research grant for a pilot study; Grant No. 10KR81002 Period: 01/01/2011-12/31/2011 Amount: $10,000 The aim of this proposal is to explore diabetes-related salivary protein biomarkers in patients with type 2 diabetes
  • 16. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  16  of  19       2011 Immediate placement and loading of dental implants into infected sites with and without antibiotics Principal investigator: Edward Givens, Jr. Agency: American College of Prosthodontists (ACP) Type: Mentored Research Fellowship Award Period: 01/01/2011 – 12/31/2011 Amount: $6,000 total The overall goal of this project is to examine the necessity and effectiveness of peri-operative antibiotic therapy for immediate implant placement and loading replacing a tooth with a periapical infection. Role: Faculty Mentor 2009-2010 Salivary Proteomic Profiling for Biomarkers in Diabetes Principal investigator: Heidi Kohltfarber Agency: North Carolina Translational and Clinical Sciences Institute (NCTRACS) Type: Small research grant for a pilot study, Grant no. 2KR80905 Period: 11/15/2009 – 11/14/2010 Amount: $2,000 total The overall goal of this project is to explore the possibility of using SELDI-TOF/MS to define the salivary proteomic profiles of Type I diabetic patients. 2009 Proteomic Analysis of Saliva in Patients with Denture Stomatitis: An Exploratory Study Principal investigator: Sandra Al-Tarawneh Agency: American College of Prosthodontists (ACP) Type: Mentored Research Fellowship Award Amount: $4,500 total The overall goal of this project is to explore the possibility of using SELDI-TOF/MS to define the salivary proteomic profiles of patients with and without denture stomatitis. 2009 Biomarker Validation for Candida-associated Denture Stomatitis (CADS) Principle Investigator: Sompop Bencharit Agency: GalaxoSmithKline (GSK) Type: Research grant Period: 10/01/09 – 12/31/09 Amount: total (direct) $87,500 This study aims to identify salivary biomarkers for candida-associated denture stomatis (CADS) in patients with and without CADS using mass spectrometry-proteomic analyses. 2006-2008 Clinical Research Training in Oral Diseases for Future Principal investigator: James Beck. Agency: National Institute of Dental & Craniofacial Research (NIDCR) Type: Training grant (T32) Period: 07/01/06 – 06/30/08 Amount: $160,000 (total-salary/benefit support) The program primarily focuses on training dentists in clinical research who are also enrolled in advanced clinical education programs to prepare to become academicians who can function as interactive scientists who have the ability to address the expanding opportunities in dental, oral and craniofacial clinical research. Role: Scholar
  • 17. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  17  of  19       2006-2007 Structural Analysis of Programmed Cell Death 10 (PDCD10) Principal investigator: Sompop Bencharit Agency: Faculty Creativity Fund, School of Dentistry, University of North Carolina-Chapel Hill Type: Small Grant Amount: $5,000 total The overall goal of this project is to engineer a soluble version of PDCD10 that is able to use for x-ray crystallographic and biophysical studies. 2005-2010 Structural Analysis of Cerebral Cavernous Malformations. Principal investigator: Sompop Bencharit Agency: School of Dentistry, University of North Carolina-Chapel Hill Type: Faculty Startup Fund Amount: $50,000 total The overall goal of this project is to determine the structural and functional relationships between two scaffolding proteins in cerebral cavernous malformations, OSM and Krit1. 2005-2007 Engineering Soluble Variants of Heteromeric G Protein Alpha Subunit for Structural Studies Principal investigator: Sompop Bencharit. Agency: University Research Council, University of North Carolina-Chapel Hill Type: Small Grant Period: 05/01/05 – 04/30/07 Amount: $4,000 total The overall goal of this project is to engineer a soluble version of heteromeric G protein alpha subunit that is able to use for x-ray crystallographic and biophysical studies. Role: PI Pending 2016-2019 The biological effects of e-cigarette aerosol exposure on the oral cavity Principal investigator: Sompop Bencharit Agency: NIH Type: Research Grant (R01) Amount: $1,000,000 (direct) The aim of this proposal is to examine the affect of e-cigarette aerosol exposure on salivary cytokines, oral microbiome, epithelial cell micronucleation, and oral proteome/metabolome in order to aid consumers in making more educated decisions about e-cigarette usage. This study also aims to characterize the chemical constituents of e-cigarette aerosol and correlate it with clinical/biological outcomes. Patents “Crystallized Mammalian Carboxylesterase Polypeptide and Screening Methods Employing.” Matthew R. Redinbo, Sompop Bencharit, Escher L. Howard-Williams, Christopher L. Morton, Philip M. Potter. U. S. Provisional Patent Application Serial Number 60/347,513. Filed April 22, 2002.
  • 18. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  18  of  19       PROFESSIONAL SERVICE University of North Carolina at Chapel Hill 2011-2015 Committee, Faculty Development Committee, UNC-School of Dentistry 2010-2014 Committee, Department of Periodontology Faculty Search Committee (For three different faculty positions) 2009-2012 Oral Biology PhD Admission Committee, UNC-School of Dentistry 2009-2011 Committee, UNC-School of Dentistry Dean Search Committee 2008-2013 North Carolina Dental Intern Permit Examiner, UNC-School of Dentistry 2008-2012 Advisory Committee for Associate Dean of Research, UNC-School of Dentistry 2001-2002 Graduate Student Representative in the Graduate Program Directors Meeting, UNC- School of Dentistry, Chapel Hill, NC. Peer Review Grants, Journals, Editorial Boards, and Editors 2013- Academic Editor, PLOS ONE 2011- Associate Editor, Regenerative Dentistry and Implant Therapy 2012- Executive Editor, Dentistry: Current Research 2014- Editorial Board Member, Scientific Reports 2014- Editorial Board: Journal of Prosthodontics 2012- Editorial Board and Reviewer, ISRN Structural Biology 2012- Editorial Board, International Journal of Clinical Pharmacology & Toxicology 2011- Editorial Board, Dentistry: Current Research 2011- Editorial Board, Journal of Anaplastology 2011- Editorial Board, Advances in Pharmacoepidemiology & Drug Safety 2010- Editorial Board, Journal of Pharmacogenomics & Pharmacoproteomics 2007- Editorial Board, The Open Dentistry Journal 2015 Ad Hoc Reviewer, Expert review of Molecular Diagnosis 2014 Ad Hoc Reviewer, Applied and Environmental Microbiology 2013 Ad Hoc Reviewer, Powder Technology 2012 Ad Hoc Reviewer, RSC Advances 2012 Ad Hoc Reviewer, MICS Publishing Group/Clinical Journals (>18 journals) 2012 Ad Hoc Reviewer, BMC Physiology 2011 Ad Hoc Reviewer, Clinical Vaccine and Immunology 2011 Ad Hoc Reviewer, Journal of Proteomics 2011 Ad Hoc Reviewer, Polymer Chemistry 2011 Ad Hoc Reviewer, Recent Patents on Biomarkers 2011- Ad Hoc Reviewer, International Journal of Medical Sciences 2011- Ad Hoc Reviewer, PLoS ONE 2011- Ad Hoc Reviewer, Journal of Oral Implantology 2011- Ad Hoc Reviewer, Molecular Biosystems 2010-2013 Ad Hoc Reviewer, Journal of Structural Biology and Systems Biology 2010-2013 Ad Hoc Reviewer, Journal of American Dental Association 2009- Ad Hoc Reviewer, International Journal of Oral and Maxillofacial Implants 2009- Ad Hoc Reviewer, Journal of Dental Education 2004 Ad Hoc Reviewer, Journal of Molecular Biology Scientific Peer Review (International)
  • 19. Sompop  Bencharit,  DDS,  MS,  PhD,  FACP   Curriculum  Vitae,  Page  19  of  19       2013 Study Section, Italian Ministry of Health-General Direction for Health and Biomedical Research and Health Research Institutions 2011 Study Section, Romanian National Research Council 2010 Study Section, Italian Ministry of Health-Young Investigator Award Other Professional Service 2014-2018 Secretary and Treasurer, Salivary Research Group (SRG), International Association of Dental Research (IADR) 2012 Organizing Committee, 2nd Conference on Proteomics & Bioinformatics, July 2012, Las Vegas, NV 2012 Poster Presentation Session Chair-Salivary Diagnostics, International Association of Dental Research Meeting, San Diego, CA 2011 Table Clinic Judge, American College of Prosthodontists (ACP) Annual Meeting, Scottsdale, AZ 2011 Oral Presentation Session Chair-Salivary Diagnostics, International Association of Dental Research Meeting, San Diego, CA 2010 Reviewer, Poster presentation, American Dental Education Association Meeting 1995-1996 Committee and Secretary, Thai Dental Implant Society 1995-1996 Academic Committee, Thai Prosthodontic Society 1995 Organizing Committee, the 1st International Dental Implant Congress, Bangkok Thailand 1994 Organizing Committee, the Annual Meeting of the Dental Association of Thailand 1994 Organizing Committee, the 1st Thailand Dental Education Congress Other Service and Engagement 1999-2003 UNC Tae Kwon Do Club: Advisor 1998-2000 UNC Badminton Club: Co-founder and Secretary Society Memberships 2014- American Dental Association 2014- North Carolina Dental Society 2014- Southeastern Academy of Prosthodontics 2006- American Dental Education Association 2006- Angioma Alliance 2005- Academy of Osseointegration 2001- International Association of Dental Research 2001- American Association of Dental Research 2001- American Crystallography Association 1997- American College of Prosthodontists 1995- Thai Prosthodontic Society 1995- Thai Dental Implant Society 1994- The Dental Association of Thailand