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WORLD’S FIRST HUMAN
HEAD TRANSPLANTATION
PRESENTATION
BY
SIDDHARTHA GHOSH
MECHANICAL
3RD YEAR
HUMAN HEAD TRANSPLANTATION
WHAT IS SURGERY ?
Surgery (via Latin: chirurgiae , meaning "hand work") is
an ancient medical specialty that uses operative
manual and instrumental techniques on a patient to
investigate or treat a pathological condition such as
a disease or injury, to help improve bodily function or
appearance or to repair unwanted ruptured areas (for
example, a perforated ear drum).
WHAT IS TRANSPLANT
Organ transplantation is a medical procedure in which
an organ is removed from one body and placed in the
body of a recipient, to replace a damaged or missing
organ. The donor and recipient may be at the same
location, or organs may be transported from
a donor site to another
location. Organs and/or tissues that are transplanted
within the same person's body are called autografts .
Transplants that are recently performed between two
subjects of the same species are called allografts.
Allografts can either be from a living or cadaveric
source.
NEED OF HEAD TRANSPLANT
It,s a rare motor neuron disease known as Werdnig-Hoffmann
Disease. The disease causes motor neurons – the nerve cells
responsible for sending signals from the central nervous system
to your muscles – to deteriorate, which leads to muscle atrophy
and in severe cases, difficulty swallowing and breathing.
Currently there is no treatment for this disease . So for now
surgeons are preferring the HEAD TRANSPLANT SURGERY
INTRODUCTION
Earlier this year Italian neuroscientist Sergio Canavero shocked
the world when he announced he would perform the world’s
first human head transplant. This week Canavero announced the
procedure is scheduled on December 2017, and he has recruited
a head surgeon (pun intended) to lead the controversial
procedure. This operation may sound like something out of a
horror movie, but one man is hoping it will improve his quality
of life.
THE VOLUNTEER
 Canavero said his first patient will be Chinese despite previously suggesting it
would be Valery Spiridonov , a Russian tech scientist who suffers from a rare
muscle-wasting disorder. Canavero had pointed out that Spiridonov could not
receive a donor body in China due to biological and ethical reasons.
 The Russian tech scientist , who is the volunteer also says that-“When I realized
that I could participate in something really big and important, I had no doubt left
in my mind and started to work in this direction,” Spiridonov, a Russian computer
scientist, told Central European News (CEN). “The only thing I feel is the sense of
pleasant impatience, like I have been preparing for something important all my
life and it is starting to happen.”
PROCEDURE
 As with any surgery, this procedure has many risks and uncertainties. Will the
doctors be able to reconnect the spinal cord? Will the head reject the new body?
While advances in medicine reduce the risk of rejection, the surgery is not a
guaranteed success as no doctor has ever successfully reconnected a spinal cord.
Spiridonov is well aware of the risks and is determined to go through with the
procedure.
 “According to Canavero’s calculations, if everything goes to plan, two years is the
time frame needed to verify all scientific calculations and plan the procedure’s
details,” Spiridonov told CEN. “It isn’t a race. No doubt, the surgery will be done
once the doctor and the experts are 99 percent sure of its success.”
PROCEDURE
 Canavero will be teaming up with Xiaoping Ren, a neurosurgeon from China’s
Harbin Medical University. Ren is no stranger to head transplants as he
has performed the procedure on 1,000 different mice. Following a 10-hour
procedure, the mice were able to breathe, drink, and even see. Unfortunately,
none of the mice survived for longer than a few minutes.
 Ren has been operating on mice for a only few years; however, the first successful
head transplant actually occurred nearly 50 years ago. In 1970 Dr. Robert White , a
surgeon at Case Western Reserve’s School of Medicine, successfully transferred a
rhesus monkey head to a new body. Following the procedure, the
monkey survived on life support for a total of nine days before the head ultimately
rejected the new body. As the spinal cord could not be reconnected the
monkey body was paralyzed below the transplanted head.
RATS HEAD TRANSPLANT
 Here are some videos
MONKEY HEAD TRANSPLANT
FUTURE ASPECTS
The duo will spend the next two years prepping for the grueling 36 hour
surgery. After cleanly severing the spinal cord , arguably the most important
part of the procedure , the head will be transferred to the donor body. Then
comes the really tricky part: reconnecting the spinal cord. Canavero’s
technique will be to use polyethylene glycol – a compound known for its
ability to fuse fatty cell membranes. Ren is expected to test Canavero’s
technique in mice and monkeys later this year.
CONCLUSION
Many medical professionals do not embrace this procedure, describing it as
outlandish and impossible. While surviving such a complicated and intricate
surgery is highly unlikely, it could help restore independence for the severely
disabled. And some people, like Spiridonov , feel it's worth the risk.
Anyhow, if this surgery can being successfully performed ,then it will write a
history in medical science.
THANK YOU

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World’s first human head transplantation

  • 1. WORLD’S FIRST HUMAN HEAD TRANSPLANTATION PRESENTATION BY SIDDHARTHA GHOSH MECHANICAL 3RD YEAR
  • 3. WHAT IS SURGERY ? Surgery (via Latin: chirurgiae , meaning "hand work") is an ancient medical specialty that uses operative manual and instrumental techniques on a patient to investigate or treat a pathological condition such as a disease or injury, to help improve bodily function or appearance or to repair unwanted ruptured areas (for example, a perforated ear drum).
  • 4. WHAT IS TRANSPLANT Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The donor and recipient may be at the same location, or organs may be transported from a donor site to another location. Organs and/or tissues that are transplanted within the same person's body are called autografts . Transplants that are recently performed between two subjects of the same species are called allografts. Allografts can either be from a living or cadaveric source.
  • 5. NEED OF HEAD TRANSPLANT It,s a rare motor neuron disease known as Werdnig-Hoffmann Disease. The disease causes motor neurons – the nerve cells responsible for sending signals from the central nervous system to your muscles – to deteriorate, which leads to muscle atrophy and in severe cases, difficulty swallowing and breathing. Currently there is no treatment for this disease . So for now surgeons are preferring the HEAD TRANSPLANT SURGERY
  • 6. INTRODUCTION Earlier this year Italian neuroscientist Sergio Canavero shocked the world when he announced he would perform the world’s first human head transplant. This week Canavero announced the procedure is scheduled on December 2017, and he has recruited a head surgeon (pun intended) to lead the controversial procedure. This operation may sound like something out of a horror movie, but one man is hoping it will improve his quality of life.
  • 7. THE VOLUNTEER  Canavero said his first patient will be Chinese despite previously suggesting it would be Valery Spiridonov , a Russian tech scientist who suffers from a rare muscle-wasting disorder. Canavero had pointed out that Spiridonov could not receive a donor body in China due to biological and ethical reasons.  The Russian tech scientist , who is the volunteer also says that-“When I realized that I could participate in something really big and important, I had no doubt left in my mind and started to work in this direction,” Spiridonov, a Russian computer scientist, told Central European News (CEN). “The only thing I feel is the sense of pleasant impatience, like I have been preparing for something important all my life and it is starting to happen.”
  • 8. PROCEDURE  As with any surgery, this procedure has many risks and uncertainties. Will the doctors be able to reconnect the spinal cord? Will the head reject the new body? While advances in medicine reduce the risk of rejection, the surgery is not a guaranteed success as no doctor has ever successfully reconnected a spinal cord. Spiridonov is well aware of the risks and is determined to go through with the procedure.  “According to Canavero’s calculations, if everything goes to plan, two years is the time frame needed to verify all scientific calculations and plan the procedure’s details,” Spiridonov told CEN. “It isn’t a race. No doubt, the surgery will be done once the doctor and the experts are 99 percent sure of its success.”
  • 9. PROCEDURE  Canavero will be teaming up with Xiaoping Ren, a neurosurgeon from China’s Harbin Medical University. Ren is no stranger to head transplants as he has performed the procedure on 1,000 different mice. Following a 10-hour procedure, the mice were able to breathe, drink, and even see. Unfortunately, none of the mice survived for longer than a few minutes.  Ren has been operating on mice for a only few years; however, the first successful head transplant actually occurred nearly 50 years ago. In 1970 Dr. Robert White , a surgeon at Case Western Reserve’s School of Medicine, successfully transferred a rhesus monkey head to a new body. Following the procedure, the monkey survived on life support for a total of nine days before the head ultimately rejected the new body. As the spinal cord could not be reconnected the monkey body was paralyzed below the transplanted head.
  • 10. RATS HEAD TRANSPLANT  Here are some videos
  • 12. FUTURE ASPECTS The duo will spend the next two years prepping for the grueling 36 hour surgery. After cleanly severing the spinal cord , arguably the most important part of the procedure , the head will be transferred to the donor body. Then comes the really tricky part: reconnecting the spinal cord. Canavero’s technique will be to use polyethylene glycol – a compound known for its ability to fuse fatty cell membranes. Ren is expected to test Canavero’s technique in mice and monkeys later this year.
  • 13. CONCLUSION Many medical professionals do not embrace this procedure, describing it as outlandish and impossible. While surviving such a complicated and intricate surgery is highly unlikely, it could help restore independence for the severely disabled. And some people, like Spiridonov , feel it's worth the risk. Anyhow, if this surgery can being successfully performed ,then it will write a history in medical science.