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ACCORDING TO WHO
CONTD…..
 It is estimated that 70,000 children below the age of 15 are
living with HIV in India .
(According to UNICEF,2011)
 In Karnataka there is 2.5 lakh people with HIV.
( THE HINDU MAY 2, 2012)
CONTD…..
 India is home to the third largest number of people living
with HIV in the world.
 The vast majority of HIV infections in India occur through
sexual transmission (85.6 per cent).
 In India, the prevalence of HIV among 15-19-year-olds is
0.04 per cent and that among 20-24 year olds is 0.18 per
cent.
(According to UNICEF, 2011)
WHO 2011 , WORLD AIDS DAY - THEME
 Between 2011-2015, World AIDS Days will have the
theme of "Getting to zero: zero new HIV infections. Zero
discrimination. Zero AIDS related deaths". The World
AIDS Campaign focus on "Zero AIDS related deaths"
signifies a push towards greater access to treatment for all;
a call for governments to act now. It is a call to honor
promises like the Abuja declaration and for African
governments to at least hit targets for domestic spending
on health and HIV.
DEFINITION OF AIDS
Acquired Immunodeficiency syndrome (AIDS) is a
condition in which a person tell-tale assortment of infections
due to the progressive destruction of immune system cells
by human immunodeficiency virus. AIDS represents the end
stage of infection by HIV.
SOURCE
ETIOLOGY
 Retrovirus
 Sexual intercourse
 Infected blood
 Transplacental
 During labour and delivery
 Breast milk
 Bisexual partners
 Use of injectable drugs
 Rarely by blood transfusion
MODES OF TRANSMISSION
CONTD…………
CONTD………
CONTD…..
CONTD…..
Average per act risk of getting HIV
 By exposure route to an infected source
 Exposure route Chance of infection
 Blood transfusion 90% [27]
 Childbirth (to child) 25%[28]
 Needle-sharing injection drug use 0.67%[27]
 Percutaneous needle stick 0.30%[29]
 Receptive anal intercourse* 0.04–3.0%[30]
 Insertive anal intercourse* 0.03%[31]
 Receptive penile-vaginal intercourse* 0.05–0.30%[30][32]
 Insertive penile-vaginal intercourse* 0.01–0.38% [30][32]
 Receptive oral intercourse* 0.04% [30]
 Insertive oral intercourse* 0.005%[33]
LIFE CYCLE OF HIV VIRUS
1.BINDING
2. REVERSE TRANSCRIPTION
3. INTEGRATION
4. TRANSCRIPTION
5.TRANSLATION
6.VIRALASSEMBLY AND MATURATION
PATHOPHYSIOLOGY
CLINICAL STAGES
CLINICAL FEATURES
Clinical manifestation of HIV Clinical manifestation AIDS
 Lymphadenopathy
 Hepatospleenomegaly
 Oral candidiasis
 Chronic or recurrent diarrohea
 Failure to thrive
 Developmental delay
 parortitis
 Pneumocystis carinii
pneumonia
 Lymphoid intestinal
pneumonitis
 Wasting of muscle
 Candida esophagitis
 HIV encephalopathy
 Cytomegalovirus
 Herpes simplex disease
DIAGNOSTIC EVALUATION
TREATMENT
 REVERSE TRANSCRIPTASE INHIBITORS
 Zidovudine (ZDV previously called AZT)
 Didanosine (ddl)
 Stavudine (d4t®)
 Trizivir
 PROTEASE INHIBITORS
 Nelfinavir
 Saquinavir
 Ritonavir
 Indinavir
ANTIRETROVIRAL DRUG THERAPY
PREVENTION OF MOTHER TO CHILD
TRANSMISSION
 Prenatal care
 Intrapartum care
 Postpartum care
NURSING DIAGNOSIS AND INTERVENTION
 Risk for infection related to impaired body defenses,
presence of ineffective organism.
 Imbalanced nutrition less than body requirement related to
recurrent illness, diarrheal losses, loss of appetite, oral
candidiasis.
 Impaired social interaction related to physical limitations,
hospitalizations, and social stigma towards HIV.
 Ineffective sexuality patterns related to risk of disease
transmission.
 Chronic pain related to disease process.
NATIONAL PROGRAMMES
National AIDS prevention and control programme
 Launched in 1987.
 1992 National AIDS Control Organization
 5 year HIV/AIDS Control Project from September 1992
to September 1997.
The project was later on extended upto March 1999 .
 The Phase II (1991-2004) of the National AIDS Control
Programme has become effective from 9th November,
1999.
CONTD……
The National AIDS Control Programme Phase II has
two key objectives
 To reduce the spread of HIV infection in India; and
 To strengthen India's capacity to respond to HIV / AIDS
on a long term basis.
National AIDS Prevention and Control Policy
 In April 2002, the Government of India approved the National
AIDS Prevention and Control Policy.
 The objectives include reduction of the impact of epidemic and
to bring about a zero transmission rate of AIDS by year 2007
 Condom promotion.
 IEC campaign, RRE- red ribbon express
2007 DEC 1ST -2008 DEC 1ST , 27000 KM, 180 DISTRICT,
41334 villages and reached to 6.2 million people, 1,16,183 people
counselled
 Access to safe blood.
 ICT
Contd
 PPTCT- PREVENTION OF PARENT TO CHILD
TRANSMISSION.
 RTI and STD management.
 PEP- post exposure prophylaxis.
 Intersectoral co-ordination and mainstreaming.
1,215 centres to predict HIV trends.
4,987 counselling centres.
3,452 pptct
211 ART centres,
NATIONAL PAEDIATRIC HIV/AIDS
INITIATIVE
 Launched in NOV 2006.
 47,784 children registered as living with HIV/AIDS
(CLHAs)
CONCLUSION
JOURNAL ABSTRACT
 A study conducted by Siegel D, Lazarus N, Krasnovsky
F, Durbin M, Chesney M. Depts. of Epidemiology,
University of California, San Francisco, to gain
information about AIDS knowledge, attitudes, and
behavior of junior high school students, 1,967 students in
three junior high schools in an inner city school district
were surveyed. Ages of the participants ranged from 11-16
years. The findings support the possibility that improving
knowledge about HIV transmission would result in more
tolerance toward students with HIV infection and would
result in less high-risk behavior.
THANK
YOU

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Human immunodeficiency virus in children .PPT.pptx

  • 1.
  • 2.
  • 4. CONTD…..  It is estimated that 70,000 children below the age of 15 are living with HIV in India . (According to UNICEF,2011)  In Karnataka there is 2.5 lakh people with HIV. ( THE HINDU MAY 2, 2012)
  • 5. CONTD…..  India is home to the third largest number of people living with HIV in the world.  The vast majority of HIV infections in India occur through sexual transmission (85.6 per cent).  In India, the prevalence of HIV among 15-19-year-olds is 0.04 per cent and that among 20-24 year olds is 0.18 per cent. (According to UNICEF, 2011)
  • 6. WHO 2011 , WORLD AIDS DAY - THEME  Between 2011-2015, World AIDS Days will have the theme of "Getting to zero: zero new HIV infections. Zero discrimination. Zero AIDS related deaths". The World AIDS Campaign focus on "Zero AIDS related deaths" signifies a push towards greater access to treatment for all; a call for governments to act now. It is a call to honor promises like the Abuja declaration and for African governments to at least hit targets for domestic spending on health and HIV.
  • 7. DEFINITION OF AIDS Acquired Immunodeficiency syndrome (AIDS) is a condition in which a person tell-tale assortment of infections due to the progressive destruction of immune system cells by human immunodeficiency virus. AIDS represents the end stage of infection by HIV.
  • 9. ETIOLOGY  Retrovirus  Sexual intercourse  Infected blood  Transplacental  During labour and delivery  Breast milk  Bisexual partners  Use of injectable drugs  Rarely by blood transfusion
  • 15. Average per act risk of getting HIV  By exposure route to an infected source  Exposure route Chance of infection  Blood transfusion 90% [27]  Childbirth (to child) 25%[28]  Needle-sharing injection drug use 0.67%[27]  Percutaneous needle stick 0.30%[29]  Receptive anal intercourse* 0.04–3.0%[30]  Insertive anal intercourse* 0.03%[31]  Receptive penile-vaginal intercourse* 0.05–0.30%[30][32]  Insertive penile-vaginal intercourse* 0.01–0.38% [30][32]  Receptive oral intercourse* 0.04% [30]  Insertive oral intercourse* 0.005%[33]
  • 16. LIFE CYCLE OF HIV VIRUS
  • 25. CLINICAL FEATURES Clinical manifestation of HIV Clinical manifestation AIDS  Lymphadenopathy  Hepatospleenomegaly  Oral candidiasis  Chronic or recurrent diarrohea  Failure to thrive  Developmental delay  parortitis  Pneumocystis carinii pneumonia  Lymphoid intestinal pneumonitis  Wasting of muscle  Candida esophagitis  HIV encephalopathy  Cytomegalovirus  Herpes simplex disease
  • 26.
  • 27.
  • 29. TREATMENT  REVERSE TRANSCRIPTASE INHIBITORS  Zidovudine (ZDV previously called AZT)  Didanosine (ddl)  Stavudine (d4t®)  Trizivir
  • 30.  PROTEASE INHIBITORS  Nelfinavir  Saquinavir  Ritonavir  Indinavir
  • 32. PREVENTION OF MOTHER TO CHILD TRANSMISSION  Prenatal care  Intrapartum care  Postpartum care
  • 33. NURSING DIAGNOSIS AND INTERVENTION  Risk for infection related to impaired body defenses, presence of ineffective organism.  Imbalanced nutrition less than body requirement related to recurrent illness, diarrheal losses, loss of appetite, oral candidiasis.  Impaired social interaction related to physical limitations, hospitalizations, and social stigma towards HIV.  Ineffective sexuality patterns related to risk of disease transmission.  Chronic pain related to disease process.
  • 34. NATIONAL PROGRAMMES National AIDS prevention and control programme  Launched in 1987.  1992 National AIDS Control Organization  5 year HIV/AIDS Control Project from September 1992 to September 1997. The project was later on extended upto March 1999 .  The Phase II (1991-2004) of the National AIDS Control Programme has become effective from 9th November, 1999.
  • 35. CONTD…… The National AIDS Control Programme Phase II has two key objectives  To reduce the spread of HIV infection in India; and  To strengthen India's capacity to respond to HIV / AIDS on a long term basis.
  • 36. National AIDS Prevention and Control Policy  In April 2002, the Government of India approved the National AIDS Prevention and Control Policy.  The objectives include reduction of the impact of epidemic and to bring about a zero transmission rate of AIDS by year 2007  Condom promotion.  IEC campaign, RRE- red ribbon express 2007 DEC 1ST -2008 DEC 1ST , 27000 KM, 180 DISTRICT, 41334 villages and reached to 6.2 million people, 1,16,183 people counselled  Access to safe blood.  ICT
  • 37. Contd  PPTCT- PREVENTION OF PARENT TO CHILD TRANSMISSION.  RTI and STD management.  PEP- post exposure prophylaxis.  Intersectoral co-ordination and mainstreaming. 1,215 centres to predict HIV trends. 4,987 counselling centres. 3,452 pptct 211 ART centres,
  • 38. NATIONAL PAEDIATRIC HIV/AIDS INITIATIVE  Launched in NOV 2006.  47,784 children registered as living with HIV/AIDS (CLHAs)
  • 40. JOURNAL ABSTRACT  A study conducted by Siegel D, Lazarus N, Krasnovsky F, Durbin M, Chesney M. Depts. of Epidemiology, University of California, San Francisco, to gain information about AIDS knowledge, attitudes, and behavior of junior high school students, 1,967 students in three junior high schools in an inner city school district were surveyed. Ages of the participants ranged from 11-16 years. The findings support the possibility that improving knowledge about HIV transmission would result in more tolerance toward students with HIV infection and would result in less high-risk behavior.