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AIDS
What do you mean by AIDS?
 HIV stands for human immunodeficiency
virus.
 It is a virus that cause AIDS(acquired immune
deficiency syndrome).
 The virus destroys a type of white blood cell
called a T-helper cell and makes copies of itself
inside them.
 If a person suffers from AIDS, they will find it
harder to fight off infections and diseases .
 There are many different strains of HIV .The
two main types are:
 HIV-1: the most common type found
worldwide
 HIV-2: this is found mainly in Western
Africa, with some cases in India and Europe.
The red ribbon is a symbol for
solidarity with HIV-positive people
and those living with AIDS.
Discovery
 AIDS was first clinically observed in 1981 in the
United States
 The initial cases were a cluster of injecting drug
users and homosexual men with no known
cause of impaired immunity who showed
symptoms of Pneumocystis carinii pneumonia
(PCP), a rare opportunistic infection that was
known to occur in people with very
compromised immune system
 In 1983, two separate research groups led by
Robert Gallo and Luc Montagnier declared that
a novel retrovirus may have been infecting
people with AIDS, and published their findings
in the same issue of the journal Science.
The Morbidity and
Mortality Weekly Report
reported in 1981 on what
was later to be called
"AIDS"
SYMPTOMS
There are three main stages of
HIV infection:
1. acute infection,
2. clinical latency
3. AIDS
ACUTE HIV INFECTION
•The initial period following the
contraction of HIV is called
acute HIV, primary HIV or acute
retroviral syndrome
•. Many individuals develop an
influenza-like illness or a
mononucleosis-like illness 2–4
weeks post exposure while
others have no significant
symptoms
•Due to their nonspecific
character, these symptoms are
not often recognized as signs of
HIV infection.
CLINICAL LATENCY
 The initial symptoms are followed by a stage
called clinical latency, asymptomatic HIV, or
chronic HIV.Without treatment, this second
stage of the natural history of HIV infection can
last from about three years to over 20 years
 While typically there are few or no symptoms at
first, near the end of this stage many people
experience fever, weight loss, gastrointestinal
problems and muscle pains. Between 50 and
70% of people also develop persistent
generalized lymphadenopathy, characterized by
unexplained, non-painful enlargement of more
than one group of lymph nodes (other than in
the groin) for over three to six months.
AIDS
 Acquired immunodeficiency syndrome
(AIDS) is defined in terms of either a CD4+ T
cell count below 200 cells per µL or the
occurrence of specific diseases in association
with an HIV infection . In the absence of
specific treatment, around half of people
infected with HIV develop AIDS within ten
years and they die within a short period of
20 months
 People with AIDS have an increased risk of
developing various viral-induced cancers,
including Kaposi's sarcoma, Burkitt's
lymphoma, primary central nervous ,system
lymphoma, and cervical cancer
HIV virus that cause AIDS
Diagnosis
 HIV/AIDS is diagnosed via laboratory
testing and then staged based on the
presence of certain signs or symptoms
 HIV testing
Most people infected with HIV develop
specific antibodies (i.e. seroconvert)
within three to twelve weeks of the initial
infection.Diagnosis of primary HIV
before seroconversion is done by
measuring HIV-RNA or p24
antigen.Positive results obtained by
antibody or PCR testing are confirmed
either by a different antibody or by PCR.
 ELISA and Western blot are two common
and accurate HIV tests
An HIV testing kit
Transmission
•Unprotected sexual practice
•Needle sharing :usage of
unsterilized syringes in hospitals
and among drug abusers
•Mother to baby:HIV can pass from
HIV positive mother to child
•Blood transfusions and transplants
from the HIV positive donor
•Healthcare Workers who get
exposed to infected blood or body
fluids
PREVENTION
 Safe sexual practice : usage of
condom reduces the risk of
transmission
 Usage of disposable medical
equipments
 Screening of blood donors
 Cesarean section of infected
pregnant women& usage of
interferon during early stage of
pregnancy
 Bottlefeeding instead of brest
feeding if mother is infected
Before and after AIDS
Treatment
 No curative treatment available
 Only disease control can be
achieved with treatment
 Treatment can only postpone
death due to AIDS
 Antiviral drugs like
Zidovudine,Lamivudine
etc…are used for primary
treatment
What we can do for AIDS patients?
 Organise counseling and emotional
support for people with HIV/AIDS
and their families.
 Set up organisations that bring
together people living with
HIV/AIDS to fight for change.
 Set up wellness programmes and
medical treatment to help people
keep their immune systems strong
and fight opportunistic infections.
 Organise grants, food parcels and
poverty alleviation projects to help
families survive.
 Provide home-based care and
medical treatment for people who are
ill.
 Treat them equal .let them also live
their life with a smile
Interacting with aids patients is one of
the best help that we can give to these
patients
WRONG FACTS ABOUT HIV SPREAD
World AIDS Day
 World AIDS Day, designated on December
1 every year since 1988, is dedicated to
raising awareness of the AIDS pandemic
caused by the spread of HIV infection, and
mourning those who have died of the
disease. Government and health officials,
non-governmental organizations and
individuals around the world observe the
day, often with education on AIDS
prevention and control.
 World AIDS Day is one of the eight official
global public health campaigns marked by
the World Health Organization (WHO)
CONCLUSION
 AIDS is a chronic disease that can affect a
person physically as well as mentally
 It is not curative. So prevention is better
than cure.
 We have to provide help to AIDS affected
people.
ADD COLOUR TO THEIR LIFE ALSO
Bibliography
 www.wikipedia.org
 www.AVERT.org
 Oxford Handbook of Clinical Medicine(fifth edition)
What is AIDS

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What is AIDS

  • 1.
  • 3. What do you mean by AIDS?  HIV stands for human immunodeficiency virus.  It is a virus that cause AIDS(acquired immune deficiency syndrome).  The virus destroys a type of white blood cell called a T-helper cell and makes copies of itself inside them.  If a person suffers from AIDS, they will find it harder to fight off infections and diseases .  There are many different strains of HIV .The two main types are:  HIV-1: the most common type found worldwide  HIV-2: this is found mainly in Western Africa, with some cases in India and Europe. The red ribbon is a symbol for solidarity with HIV-positive people and those living with AIDS.
  • 4. Discovery  AIDS was first clinically observed in 1981 in the United States  The initial cases were a cluster of injecting drug users and homosexual men with no known cause of impaired immunity who showed symptoms of Pneumocystis carinii pneumonia (PCP), a rare opportunistic infection that was known to occur in people with very compromised immune system  In 1983, two separate research groups led by Robert Gallo and Luc Montagnier declared that a novel retrovirus may have been infecting people with AIDS, and published their findings in the same issue of the journal Science. The Morbidity and Mortality Weekly Report reported in 1981 on what was later to be called "AIDS"
  • 5. SYMPTOMS There are three main stages of HIV infection: 1. acute infection, 2. clinical latency 3. AIDS
  • 6. ACUTE HIV INFECTION •The initial period following the contraction of HIV is called acute HIV, primary HIV or acute retroviral syndrome •. Many individuals develop an influenza-like illness or a mononucleosis-like illness 2–4 weeks post exposure while others have no significant symptoms •Due to their nonspecific character, these symptoms are not often recognized as signs of HIV infection.
  • 7. CLINICAL LATENCY  The initial symptoms are followed by a stage called clinical latency, asymptomatic HIV, or chronic HIV.Without treatment, this second stage of the natural history of HIV infection can last from about three years to over 20 years  While typically there are few or no symptoms at first, near the end of this stage many people experience fever, weight loss, gastrointestinal problems and muscle pains. Between 50 and 70% of people also develop persistent generalized lymphadenopathy, characterized by unexplained, non-painful enlargement of more than one group of lymph nodes (other than in the groin) for over three to six months.
  • 8. AIDS  Acquired immunodeficiency syndrome (AIDS) is defined in terms of either a CD4+ T cell count below 200 cells per µL or the occurrence of specific diseases in association with an HIV infection . In the absence of specific treatment, around half of people infected with HIV develop AIDS within ten years and they die within a short period of 20 months  People with AIDS have an increased risk of developing various viral-induced cancers, including Kaposi's sarcoma, Burkitt's lymphoma, primary central nervous ,system lymphoma, and cervical cancer HIV virus that cause AIDS
  • 9. Diagnosis  HIV/AIDS is diagnosed via laboratory testing and then staged based on the presence of certain signs or symptoms  HIV testing Most people infected with HIV develop specific antibodies (i.e. seroconvert) within three to twelve weeks of the initial infection.Diagnosis of primary HIV before seroconversion is done by measuring HIV-RNA or p24 antigen.Positive results obtained by antibody or PCR testing are confirmed either by a different antibody or by PCR.  ELISA and Western blot are two common and accurate HIV tests An HIV testing kit
  • 10. Transmission •Unprotected sexual practice •Needle sharing :usage of unsterilized syringes in hospitals and among drug abusers •Mother to baby:HIV can pass from HIV positive mother to child •Blood transfusions and transplants from the HIV positive donor •Healthcare Workers who get exposed to infected blood or body fluids
  • 11. PREVENTION  Safe sexual practice : usage of condom reduces the risk of transmission  Usage of disposable medical equipments  Screening of blood donors  Cesarean section of infected pregnant women& usage of interferon during early stage of pregnancy  Bottlefeeding instead of brest feeding if mother is infected Before and after AIDS
  • 12. Treatment  No curative treatment available  Only disease control can be achieved with treatment  Treatment can only postpone death due to AIDS  Antiviral drugs like Zidovudine,Lamivudine etc…are used for primary treatment
  • 13. What we can do for AIDS patients?  Organise counseling and emotional support for people with HIV/AIDS and their families.  Set up organisations that bring together people living with HIV/AIDS to fight for change.  Set up wellness programmes and medical treatment to help people keep their immune systems strong and fight opportunistic infections.  Organise grants, food parcels and poverty alleviation projects to help families survive.  Provide home-based care and medical treatment for people who are ill.  Treat them equal .let them also live their life with a smile Interacting with aids patients is one of the best help that we can give to these patients
  • 14. WRONG FACTS ABOUT HIV SPREAD
  • 15. World AIDS Day  World AIDS Day, designated on December 1 every year since 1988, is dedicated to raising awareness of the AIDS pandemic caused by the spread of HIV infection, and mourning those who have died of the disease. Government and health officials, non-governmental organizations and individuals around the world observe the day, often with education on AIDS prevention and control.  World AIDS Day is one of the eight official global public health campaigns marked by the World Health Organization (WHO)
  • 16. CONCLUSION  AIDS is a chronic disease that can affect a person physically as well as mentally  It is not curative. So prevention is better than cure.  We have to provide help to AIDS affected people. ADD COLOUR TO THEIR LIFE ALSO
  • 17. Bibliography  www.wikipedia.org  www.AVERT.org  Oxford Handbook of Clinical Medicine(fifth edition)