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Clinical Laboratories
West Virginia University Hospitals
Resident Orientation
Rocco LaSala, MD
Medical Director Clinical Laboratories
plasala@hsc.wvu.edu
Residents are IMPORTANT
in Laboratory Testing Process
Provider
Phlebotomy/Nursing
Laboratory
PreAnalytic Analytic PostAnalytic
Order
Right Test at
Right Time on
Right Patient
Collect Sample
From Right Patient at
Right Time in
Right Tube
Laboratory Testing Process Overview
Transport Sample
to Lab
Test
Specimen
Verify &
Report
Resutls
View Result
Interpret
Act
What were you taught about Lab Medicine in medical school?
Clinical Laboratories @ WVUH
• Three shifts – 24/7 service
• Level 3 Ruby (Clin Labs) & Level 2 HSC (Pathology)
• Staffed by supervisors, technologists, etc.
− Chemistry: Dr. Tacker
− Hematology & Coagulation: Dr. Perrotta
− Microbiology: Dr. LaSala / Dr. Kieffer
− Molecular Diagnostics: Dr. Smolkin
− Cytogenetics: Dr. Sasi
− Blood Bank: Dr. Shmookler / Dr. Kieffer
− Surgical Pathology: Dr. Vos
− Cytology: Dr. Flanagan
Problems are brought to supervisors & pathologists!
Regulatory Oversight
• Lab practice strictly regulated by federal and other
accrediting organizations (CMS, FDA, JC, CAP, AABB)
− CLIA Medical Director = Dr. LaSala
• MUST be a computer-entered (or written) order for each
test, and the test must be medically necessary
• Some tests require informed consent
− Genetic tests
− Blood transfusion
− HIV no longer requires written consent
Technologists CANNOT deviate from
policies/procedures without pathologist approval
Test Availability
• Tests needed for urgent care (& many others)
are available 24/7
• Tests not performed at Ruby Memorial are
sent to a reference lab (>24 hr TAT)
• Limited point-of-care testing
Turnaround Times (TAT)
• Routine: < 4 hours (usually < 2 hours)
• “STAT”: < 1 hour
− 25-50% tests ordered “STAT”
− Collected by unit/nurse
− ED TnI <30 minutes
• Timed
− Collected 1 hour before or after time by phlebotomy
Routine priority for orders usually sufficient
Testing Capabilities
• Chemistry & Hematology
Automated Core
• Specialized Testing:
• Flow cytometry
• Cytogenetics/FISH/Microarray
• Molecular (PCR): Many varieties
• Mass spectrometry
• MALDI-TOF Microbiology
• Immunohistochemistry
Electronic Test Formulary
• Comprehensive & Current
− Tests performed at WVUH
− Reference lab tests
• Includes educational
material
− Practice guidelines, algorithms,
publications
http://wvuh.testcatalog.org/
Primary Reference Lab - Mayo Medical
Test Order Entry
Hyperlinks
Use “Comments”
Sparingly
Priorities & Frequencies
Lab/Phlebotomy Collection Times
• AM Draw (0530)
− Results available early to mid-morning
• AFTERNOON Draw (1600)
− Results available later afternoon later afternoon
• NIGHT Draw (2200)
− Results available around midnight
− For discharge labs
Laboratory Resource Utilization
“Testing Wisely”
• Lab testing ~3-5% cost of healthcare
• Routine labs relatively inexpensive per test but costs add up
− Does every patient need large number of daily labs?
− Option to order daily labs (e.g. “daily x 7 days”) has been removed
with some exceptions (PT/INRs, troponin)
• Antiquated test removal: No more CK-MB testing for
myocardial injury, RBC folate, bleeding times
• Some tests are limited to outpatients & specialists (often
referred tests)
Best Practice Alerts & Pop-ups
We are sensitive to pop-up fatigue and
limit whenever possible
Duplicate Test Alerts
• Some tests are ordered more frequently than necessary:
− Physiologic: limit HbA1c every 3 months
− Genetic testing for germline mutations only needed once
− Re-ordering when you don’t see a result
− Different teams/providers ordering the same test
• Coordinated effort to decrease duplicate testing
− Alerts more effective when previous results is embedded
− Option to continue with duplicate order
− (providers tracked each month)
Right
test 1st
Reduce user
burden
Real-time
Information
Alternate Test Alerts
Ordersets & Preference Lists
• We have too many
• Poorly controlled
• Some labs
“autochecked”
Test Result Review
House Staff are Critical in the
Post-analytical Testing Phase
• Results must be retrieved and acted upon
• Critical results (“panic values”) are phoned to you &
require immediate action (if you are not sure what
to do, ask!)
− “Readback” required by JC
• Unexpected/unexplained results may need
confirmation
Let the lab know if you think
there is a problem with a result!
Blood Utilization
• Blood use decreasing but is still a major expense and
blood resources are a finite
• Blood product use monitored by the Blood Utilization
Committee
− Encourage Single RBC Unit Transfusions
• Recognize transfusion reactions
− Transfusion Manual online
• Hemolytic transfusion reactions are caused by giving
the wrong blood to the wrong patient
Transfusion Medicine
• We use apheresis platelets: An adult dose of platelets is
“1 dose” (not 2, 3, 6, 10, etc)
• Order irradiated blood products appropriately
• NOT every patient with cancer
• We won’t accept mislabeled specimens
• We have policies for emergency blood release
• We have a massive transfusion protocol
http://connect.wvuhealthcare.com/
clinical-laboratories/
Laboratory Concerns
• Direct to supervisors and/or Medical Directors
− We take complaints/concerns VERY SERIOUSLY
• Pathology residents and attendings on call 24/7 for
both Anatomic & Clinical Pathology
• We are always happy to help with test selection, test
interpretation, etc.
Remember - ordering a diagnostic test is like
picking your nose in public . . .
. . . you should first consider what you’ll do if
you find something
Please feel free to contact me or any of the
other pathologists
We look forward to working with you at WVUH
Thank you and Good Luck!

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WVUH Clinical Lab Resident Orientation Overview

  • 1. Clinical Laboratories West Virginia University Hospitals Resident Orientation Rocco LaSala, MD Medical Director Clinical Laboratories plasala@hsc.wvu.edu
  • 2. Residents are IMPORTANT in Laboratory Testing Process Provider Phlebotomy/Nursing Laboratory PreAnalytic Analytic PostAnalytic Order Right Test at Right Time on Right Patient Collect Sample From Right Patient at Right Time in Right Tube Laboratory Testing Process Overview Transport Sample to Lab Test Specimen Verify & Report Resutls View Result Interpret Act What were you taught about Lab Medicine in medical school?
  • 3. Clinical Laboratories @ WVUH • Three shifts – 24/7 service • Level 3 Ruby (Clin Labs) & Level 2 HSC (Pathology) • Staffed by supervisors, technologists, etc. − Chemistry: Dr. Tacker − Hematology & Coagulation: Dr. Perrotta − Microbiology: Dr. LaSala / Dr. Kieffer − Molecular Diagnostics: Dr. Smolkin − Cytogenetics: Dr. Sasi − Blood Bank: Dr. Shmookler / Dr. Kieffer − Surgical Pathology: Dr. Vos − Cytology: Dr. Flanagan Problems are brought to supervisors & pathologists!
  • 4. Regulatory Oversight • Lab practice strictly regulated by federal and other accrediting organizations (CMS, FDA, JC, CAP, AABB) − CLIA Medical Director = Dr. LaSala • MUST be a computer-entered (or written) order for each test, and the test must be medically necessary • Some tests require informed consent − Genetic tests − Blood transfusion − HIV no longer requires written consent Technologists CANNOT deviate from policies/procedures without pathologist approval
  • 5. Test Availability • Tests needed for urgent care (& many others) are available 24/7 • Tests not performed at Ruby Memorial are sent to a reference lab (>24 hr TAT) • Limited point-of-care testing
  • 6. Turnaround Times (TAT) • Routine: < 4 hours (usually < 2 hours) • “STAT”: < 1 hour − 25-50% tests ordered “STAT” − Collected by unit/nurse − ED TnI <30 minutes • Timed − Collected 1 hour before or after time by phlebotomy Routine priority for orders usually sufficient
  • 7. Testing Capabilities • Chemistry & Hematology Automated Core • Specialized Testing: • Flow cytometry • Cytogenetics/FISH/Microarray • Molecular (PCR): Many varieties • Mass spectrometry • MALDI-TOF Microbiology • Immunohistochemistry
  • 8. Electronic Test Formulary • Comprehensive & Current − Tests performed at WVUH − Reference lab tests • Includes educational material − Practice guidelines, algorithms, publications http://wvuh.testcatalog.org/
  • 9. Primary Reference Lab - Mayo Medical
  • 10. Test Order Entry Hyperlinks Use “Comments” Sparingly Priorities & Frequencies
  • 11. Lab/Phlebotomy Collection Times • AM Draw (0530) − Results available early to mid-morning • AFTERNOON Draw (1600) − Results available later afternoon later afternoon • NIGHT Draw (2200) − Results available around midnight − For discharge labs
  • 12. Laboratory Resource Utilization “Testing Wisely” • Lab testing ~3-5% cost of healthcare • Routine labs relatively inexpensive per test but costs add up − Does every patient need large number of daily labs? − Option to order daily labs (e.g. “daily x 7 days”) has been removed with some exceptions (PT/INRs, troponin) • Antiquated test removal: No more CK-MB testing for myocardial injury, RBC folate, bleeding times • Some tests are limited to outpatients & specialists (often referred tests)
  • 13. Best Practice Alerts & Pop-ups We are sensitive to pop-up fatigue and limit whenever possible
  • 14. Duplicate Test Alerts • Some tests are ordered more frequently than necessary: − Physiologic: limit HbA1c every 3 months − Genetic testing for germline mutations only needed once − Re-ordering when you don’t see a result − Different teams/providers ordering the same test • Coordinated effort to decrease duplicate testing − Alerts more effective when previous results is embedded − Option to continue with duplicate order − (providers tracked each month)
  • 16. Ordersets & Preference Lists • We have too many • Poorly controlled • Some labs “autochecked”
  • 18. House Staff are Critical in the Post-analytical Testing Phase • Results must be retrieved and acted upon • Critical results (“panic values”) are phoned to you & require immediate action (if you are not sure what to do, ask!) − “Readback” required by JC • Unexpected/unexplained results may need confirmation Let the lab know if you think there is a problem with a result!
  • 19. Blood Utilization • Blood use decreasing but is still a major expense and blood resources are a finite • Blood product use monitored by the Blood Utilization Committee − Encourage Single RBC Unit Transfusions • Recognize transfusion reactions − Transfusion Manual online • Hemolytic transfusion reactions are caused by giving the wrong blood to the wrong patient
  • 20. Transfusion Medicine • We use apheresis platelets: An adult dose of platelets is “1 dose” (not 2, 3, 6, 10, etc) • Order irradiated blood products appropriately • NOT every patient with cancer • We won’t accept mislabeled specimens • We have policies for emergency blood release • We have a massive transfusion protocol
  • 22. Laboratory Concerns • Direct to supervisors and/or Medical Directors − We take complaints/concerns VERY SERIOUSLY • Pathology residents and attendings on call 24/7 for both Anatomic & Clinical Pathology • We are always happy to help with test selection, test interpretation, etc.
  • 23. Remember - ordering a diagnostic test is like picking your nose in public . . . . . . you should first consider what you’ll do if you find something
  • 24. Please feel free to contact me or any of the other pathologists We look forward to working with you at WVUH Thank you and Good Luck!