Md. Saiful Islam Executive PMD REPHCO Pharmaceuticals Ltd.

1. Trecilon
Triamcinolone Acetonide
PREVENT FUTURE RELAPSES OF ALLERGIC
INFLAMMATION
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2. PRODUCT PROFILE
Brand name: Trecilon
Generic name: Triamcinolone Acetonide
Pharmacologic class: Synthetic Corticosteroid (Glucocorticoids)
Therapeutic class: Anti-inflammatory (Steroidal)
Available Strength: 40 mg IM/IA
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3. DEFINITION
 Steroid:
It is an organic compound with four rings. Steroids have two
principal biological functions: certain steroids (such as cholesterol)
are important components of cell membranes which alter membrane
fluidity and many steroids are signaling molecules which activate steroid
hormone receptors.
 Glucocorticoids:
Glucocorticoids is any of a group of steroid hormones produced by the
adrenal cortex, that are involved in metabolism & have anti-
inflammatory properties.
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4. DEFINITION
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Adrenal gland:
The adrenal glands are small structures
attached to the top of each kidney. The
human body has two adrenal glands that
release chemicals called hormones into the
blood stream. These hormones affect many
parts of the human body.

5. CLINICAL INDICATIONS
Intra-Muscular
Where oral therapy is not feasible, injectable corticosteroid therapy, including Trecilon Injection
(triamcinolone acetonide injectable suspension, USP) is indicated for intramuscular use such as:
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Allergic problems Dermatologic diseases
Endocrine disorders Gastrointestinal diseases
Hematologic disorders Opthalmic diseases

6. CLINICAL INDICATIONS
Intra- Articular
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Acute gouty arthritis Rheumatoid arthritis

7.  nausea, bloating, appetite changes;
 stomach or side pain;
 headache, sleep problems (insomnia);
 acne, scaling, or other skin changes;
 a wound that is slow to heal;
 thinning hair;
 bruising or swelling;
 sweating more than usual; or
 irregular menstrual periods.
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SIDE EFFECT

8. DOSAGE AND ADMINISTRATION
Children (6-12) years 40 mg
Adult & children over 12 years 40-80 mg
Adult 80-100 mg
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For local areas, dose for adults is up to 10 mg for smaller
and 40 mg for larger areas.
DOSAGE AND ADMINISTRATION
General

9. Systemic
Intra-muscular dosing:
 The suggested initial dose is 60 mg, injected deeply into the gluteal muscle. Dosage is usually adjusted
within the range of 40 mg to 80 mg, depending upon patient response and duration of relief.
Local
Intra-articular dosing:
 2.5 mg to 5 mg for smaller joints and from 5 mg to 15 mg for larger joints, depending on the specific
disease entity being treated. For adults, doses up to 10 mg for smaller areas and up to 40 mg for larger
areas have usually been sufficient.
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DOSAGE AND ADMINISTRATION

10. Dosage for treatment of Opthalmic diseases
The initial recommended dose of Trecilon suspension is 4 mg
(100 microliters of 40 mg/ml suspension) with subsequent
dosage as needed over the course of treatment.
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DOSAGE AND ADMINISTRATION

11. Administration:
Systemic:
Injection should be made deeply into gluteal muscle.
Local:
Usual intra-articular injection should be followed.
DOSAGE AND ADMINISTRATION
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12. PREGNANCY CATEGORY
 Pregnancy category ‘C’ :
In animal studies, pregnant animals were given this
medication and had some babies born with problems.
No well-controlled studies have been done in humans.
Therefore, this medication may be used if the potential
benefits to the mother outweigh the potential risks to
the unborn child.
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13.  More potent steroid.
 More effective than other steroids.
 Trusted efficacy across all indications.
 Convenient and cost-effective.
SELLING POINTS
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14. TARGET DOCTOR
• General Physicians
• Medicine Specialist
• Chest Specialist
• Orthopedics
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15. Cover photo

16. THANKING YOU…
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Md. Saiful
Islam
Executive PMD