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ِ‫ْم‬‫ي‬ ِ‫ح‬َّ‫الر‬ ِ‫ن‬ ٰ‫م‬ْ‫ح‬َّ‫الر‬ ِ‫هللا‬ ِ‫ْم‬‫س‬ِ‫ب‬
Unlocking The Research Journey
By Dr. Syed M Haroon
PREFACE .....................................................................................................................................................8
ACKNOWLEDGEMENT ............................................................................................................................9
INTRODUCTION ......................................................................................................................................10
What will we learn in this Booklet?............................................................................................................11
TITLE: THE EMERGENCE OF RESEARCH AND ITS REWARDS......................................................14
Introduction:................................................................................................................................................14
Section 1: Justified True Belief as the Foundation of Knowledge..........................................................14
Section 2: Research as the Means to Expand Knowledge ......................................................................14
2.1 Research as an Extension of Knowledge:.....................................................................................14
2.2 The Role of Experience, Study, and Investigation:.......................................................................14
2.3 The Justification of Belief through Research:...............................................................................14
Section 3: The Rewards of Research ......................................................................................................14
3.1 Intellectual Fulfillment:.................................................................................................................14
3.2 The “AAHH” Moment:.................................................................................................................15
Conclusion: .............................................................................................................................................15
TITLE: UNDERSTANDING RESEARCH: A SYSTEMATIC PURSUIT OF KNOWLEDGE ...............16
Introduction:................................................................................................................................................16
Section 1: Defining Research..................................................................................................................16
Section 2: Types of Research ..................................................................................................................16
2.1 Quantitative Research:..................................................................................................................16
2.2 Qualitative Research:....................................................................................................................16
2.3 Mixed Methods Research: ............................................................................................................17
Section 3: Applications and Comparisons ..............................................................................................17
3
3.1 Clinical Research and Quantitative Emphasis: .............................................................................17
3.2 Endogeneity in Qualitative Research:...........................................................................................17
3.3 Comparative Analysis in Quantitative Research:..........................................................................17
Conclusion: .............................................................................................................................................17
TITLE: SELECTING AN AREA OF INTEREST FOR RESEARCH: CONSIDERATIONS AND
CRITERIA..................................................................................................................................................18
Introduction:................................................................................................................................................18
Section 1: Broadness and Multiple Outcomes ........................................................................................18
The Significance of a Broad Area of Interest:.....................................................................................18
Section 2: Criteria for Choosing an Area of Interest...............................................................................18
2.1 Relevance:.....................................................................................................................................18
2.2 Novelty:.........................................................................................................................................18
2.3 Acceptability: ................................................................................................................................18
2.4 Cost-effectiveness:........................................................................................................................19
2.5 Ethical Issues: ...............................................................................................................................19
Section 3: Proposal Evaluation Process..................................................................................................19
3.1 Committee-Based Evaluation: ......................................................................................................19
Conclusion: .............................................................................................................................................19
TITLE: RESEARCH OBJECTIVES: SETTING SPECIFIC AND MEASURABLE INTENTIONS .......20
Introduction:................................................................................................................................................20
Subjective Elements:...............................................................................................................................20
Objective Elements:................................................................................................................................20
Section 1: The Significance of Specific Research Objectives ................................................................20
1.1 Defining Research Objectives:......................................................................................................20
1.2 Clarity through Specificity:...........................................................................................................20
Section 2: The Role of Objective Elements in Research Objectives ......................................................21
2.1 The Importance of Objective Elements or Phrases:......................................................................21
2.2 Action Words for Measurability:...................................................................................................21
2.3 Measurability, Reproducibility, and Comparability:.....................................................................21
Conclusion: .............................................................................................................................................21
TITLE: OPERATIONAL DEFINITION: ENHANCING CLARITY AND PRECISION IN RESEARCH
....................................................................................................................................................................22
Introduction:................................................................................................................................................22
Section 1: Defining Operational Definition............................................................................................22
4
1.1 Clarifying Terms and Variables:....................................................................................................22
1.2 Enhancing Clarity and Precision:..................................................................................................22
Section 2: Operational Definition as a Variable of Study .......................................................................22
2.1 The Nature of Data Collection:.....................................................................................................22
2.2 Defining Data Variables:...............................................................................................................23
Section 3: Eliminating Ambiguity through Operational Definition........................................................23
3.1 Ambiguity in Research:.................................................................................................................23
3.2 The Role of Operational Definition: .............................................................................................23
Conclusion: .............................................................................................................................................23
TITLE: LITERATURE REVIEW: A COMPREHENSIVE EXAMINATION OF KEY SOURCES.........24
Introduction:................................................................................................................................................24
Section 1: Keyword Utilization in Literature Review.............................................................................24
1.1 Importance of Keywords:..............................................................................................................24
1.2 Keyword Usage:............................................................................................................................24
Section 2: Recommended Sources for Literature Review ......................................................................24
➢ Pub Med:.....................................................................................................................................24
➢ National Institute of Health National Library of Medicine:........................................................24
➢ Academic Databases:..................................................................................................................25
➢ Academic Journals:.....................................................................................................................25
➢ Books and E-books: ....................................................................................................................25
➢ Government and Institutional Reports:.......................................................................................25
➢ Professional Associations and Organizations:.............................................................................25
➢ Theses and Dissertations:............................................................................................................25
➢ Conference Proceedings:.............................................................................................................26
Section 3: Time Investment for Literature Review.................................................................................26
3.1 Duration of Literature Review:.....................................................................................................26
Section 4: Potential for Refinement Based on Literature Review Findings ...........................................26
4.1 Adaptability of Area of Interest, Objectives, and Operational Definitions:..................................26
4.2 Critical Decision-Making Point: ...................................................................................................26
Conclusion: .............................................................................................................................................26
TITLE: CONDUCTING RESEARCH: A COMPREHENSIVE GUIDE...................................................27
Introduction:................................................................................................................................................27
Section 1: Identifying Variables in the Study..........................................................................................27
5
1.1 Variable Identification:..................................................................................................................27
Section 2: Selecting the Study Population ..............................................................................................27
2.1 Defining the Study Population:.....................................................................................................27
Section 3: Understanding Confounding Variables ..................................................................................28
3.1 Confounding Variables:.................................................................................................................28
3.2 Limitations and Unavoidable Confounding Factors: ....................................................................28
Section 4: Incorporating Confounding Factors into Objective Formulation...........................................29
4.1 Consideration of Confounding Factors:........................................................................................29
Conclusion: .............................................................................................................................................29
TITLE: STUDY DESIGN: A COMPREHENSIVE OVERVIEW..............................................................30
Introduction:................................................................................................................................................30
Section 1: Descriptive Study Designs.....................................................................................................30
1.1 Case Report:..................................................................................................................................30
1.2 Case Series:...................................................................................................................................30
1.3 Cross-sectional Study: ..................................................................................................................30
Section 2: Advantages and Considerations .............................................................................................30
2.1 Advantages:...................................................................................................................................30
2.2 Considerations: .............................................................................................................................31
Conclusion: .............................................................................................................................................31
TITLE: ANALYTICS: OBSERVATIONAL AND EXPERIMENTAL STUDY APPROACHES..............32
Introduction.............................................................................................................................................32
Section 1: Observational Studies ............................................................................................................32
1.1 Cohort Study:................................................................................................................................32
1.2 Case-Control Study:......................................................................................................................32
Section 2: Experimental Studies .............................................................................................................32
2.1 Intervention:......................................................................................................................................32
2.2 Comparison:......................................................................................................................................32
Conclusion: .............................................................................................................................................33
TITLE: SAMPLING METHODS: ENSURING REPRESENTATIVE DATA COLLECTION.................34
Introduction.............................................................................................................................................34
Section 1: Non-Probability Sampling Methods ......................................................................................34
1.1 Consecutive Sampling: .................................................................................................................34
1.2 Purposive Sampling: .....................................................................................................................34
6
1.3 Convenience Sampling: ................................................................................................................34
Section 2: Probability Sampling Methods ..............................................................................................34
2.1 Simple Random Sampling: ...........................................................................................................34
2.2 Systematic Sampling:....................................................................................................................34
2.3 Stratified Sampling: ......................................................................................................................35
2.4 Cluster Sampling:..........................................................................................................................35
Conclusion: .............................................................................................................................................35
TITLE: DATA COLLECTION METHODS: QUESTIONNAIRES, SURVEYS, AND FOCUS GROUP
DISCUSSIONS/INTERVIEWS..................................................................................................................36
Introduction:................................................................................................................................................36
Section 1: Questionnaires .......................................................................................................................36
1.1 Definition and Purpose: ................................................................................................................36
1.2 Limitations:...................................................................................................................................36
Section 2: Surveys...................................................................................................................................36
2.1 Definition and Purpose: ................................................................................................................36
2.2 Implementation and Benefits: .......................................................................................................36
Section 3: Focus Group Discussions/Interviews.....................................................................................36
3.1 Definition and Purpose: ................................................................................................................36
3.2 Implementation and Benefits: .......................................................................................................37
TITLE: DATA PREPARATION AND SUMMARIZATION IN RESEARCH...........................................38
Introduction:................................................................................................................................................38
Section 1: Data Preparation.....................................................................................................................38
1.1 Representation of Data:.................................................................................................................38
Section 2: Data Summarization Measures ..............................................................................................38
1) Mean: ..............................................................................................................................................38
2) Median: ...........................................................................................................................................38
3) Mode:..............................................................................................................................................39
4) Range: .............................................................................................................................................39
5) Variance: .........................................................................................................................................39
6) Standard Deviation:.........................................................................................................................39
Section 3: Null Hypothesis and p-value..................................................................................................40
3.1 Null Hypothesis: ...........................................................................................................................40
3.2 P-value and Hypothesis Testing:...................................................................................................40
7
Conclusion: .............................................................................................................................................40
Conceptual Breakdown ............................................................................................................................41
The epistemological framework..................................................................................................................41
Quantitative Research:................................................................................................................................42
Qualitative Research:..................................................................................................................................42
Mixed Methods Research:...........................................................................................................................42
Objective:....................................................................................................................................................43
Data Variables .............................................................................................................................................44
Types of study designs: ...............................................................................................................................45
Here you can calculate sample size easily...................................................................................................48
Cluster And Strata .......................................................................................................................................49
Standard deviation......................................................................................................................................50
Null Hypothesis ...........................................................................................................................................51
P-Value And Hypothesis Testing..................................................................................................................52
PROPOSAL WRITING ...........................................................................................................................54
QUESTIONNAIRE...................................................................................................................................64
RELIABILITY OF QUESTIONNAIRE.................................................................................................70
GANTT CHART.......................................................................................................................................72
8
PREFACE
Assalam-O-Alaikum,
I am pleased to introduce a comprehensive research guide designed to empower undergraduate
students in conducting successful research. In today's research-focused world, we understand that
students often face challenges when it comes to selecting topics, research methodology, REC
(Research Ethics Committee) approval, and publication acceptance. This guide aims to simplify
the process and provide clarity on these crucial aspects.
The purpose of this guide is to demystify research and equip you with the necessary tools to
overcome common hurdles. By focusing on the fundamentals, we aim to provide a solid
foundation for your academic journey, helping you avoid bias or rejection during the publication
process. Throughout this booklet, we delve into critical steps and considerations essential for
research success.
I attended a research workshop, which, combined with internet resources, contributed to the
creation of this guide. We value your feedback and questions, as they help us to improve and
cater to your needs. Our commitment is to support you on your research path, so please don't
hesitate to reach out with any inquiries or concerns. Thank you for your interest and support. We
look forward to being part of your research journey.
Regards,
Syed M. Haroon
syedharoon193@gmail.com
9
ACKNOWLEDGEMENT
I am delighted to express my sincere gratitude and acknowledgment to Study Aid Project,
Islamic Jamiat-e-Talaba for their invaluable support in my self-development and fostering an
Islamic worldview and paradigm. Their dedication to providing educational resources and
opportunities has played a vital role in shaping my personal growth and understanding.
I am deeply grateful to my family for their unwavering support and encouragement in every
aspect of my life. Their love, guidance, and unwavering belief in my abilities have been the
driving force behind my accomplishments.
Furthermore, I would like to extend my heartfelt appreciation to Prof. Muhammad Ilyas
Siddiqui, Chairman, Department of Community Medicine at LUMHS, for reviewing and
providing valuable feedback on my work. His expertise and insights have greatly enhanced the
quality of my research.
Sincerely,
Syed M. Haroon
Nazim e LUMHS
10
INTRODUCTION
Throughout this booklet, we delve into the critical steps and considerations that are crucial for
your research success. By following the guidelines presented, you will be able to:
1. Choose an engaging and relevant research topic: We provide strategies and tips to assist you in
selecting a research area that aligns with your interests and academic goals.
2. Determine the most suitable research methodology: We explore various research
methodologies, ensuring that you can confidently select an approach that aligns with your
research objectives.
3. Minimize bias in your research: We emphasize the significance of impartiality and offer
practical techniques to mitigate bias at every stage of your study, from design to analysis.
4. Navigate the REC approval process: We guide you through the REC application process,
providing insights to help streamline your submission and increase your chances of approval.
5. Enhance publication acceptance: We address common factors that can contribute to rejection
and provide valuable recommendations to maximize the likelihood of your research being
accepted for publication.
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What will we learn in this Booklet?
A Systematic Overview of Research Fundamentals
1. Introduction
- Provide an overview of the importance of research and its role in advancing knowledge.
- Highlight the need for a systematic approach to conducting research.
2. Area of Interest
- Explain the significance of selecting a broad and relevant area of interest.
-Discuss the criteria for choosing an area of interest, including relevance, novelty, acceptability,
cost-effectiveness, and ethical considerations.
-Mention the importance of considering the potential for multiple outcomes and the opportunity
to contribute to multiple papers/articles.
3. Research Objectives
- Define the characteristics of specific and measurable research objectives.
- Emphasize the use of action words to clearly state the intended outcomes of the research.
- Discuss the importance of aligning research objectives with the chosen area of interest.
4. Literature Review
-Explain the role of the literature review in research.
-Discuss the use of keywords and recommended sources such as Pub Med and the
National Library of Medicine.
-Highlight the time required for conducting a thorough literature review.
-Mention the potential for refining the area of interest, objectives, and operational definitions
based on the findings of the literature review.
12
5. Study Design
-Introduce different study designs, including descriptive and analytical designs.
-Discuss the characteristics and uses of descriptive designs such as case reports, case series and
cross-sectional studies.
-Explain the distinction between observational studies (cohort and case-control) and
experimental studies (intervention-based).
6. Sampling Size & Methods
- Categorize sampling methods into non-probability and probability techniques.
- Discuss non-probability methods such as consecutive and purposive sampling.
- Explain probability methods including simple random, systematic, stratified, and cluster
sampling.
7. Data Collection
- Introduce various data collection methods.
- Discuss the use of questionnaires, surveys, and focus group discussions/interviews.
- Highlight the applicability of these methods to both quantitative and qualitative research.
8. Data Preparation and Summarization
- Explain the process of data preparation.
- Discuss the representation of data through frequency tables, charts, and graphs.
- Introduce key summarization measures, including mean, median, mode, range, variance,
and standard deviation.
9. Null Hypothesis and p-value
- Define the null hypothesis and its role in research.
- Discuss the use of the p-value as a parameter in hypothesis testing.
- Mention the commonly used significance level of 0.05 for decision-making.
13
10. Conclusion
- Summarize the key components of research fundamentals.
- Highlight the importance of systematically approaching research to ensure rigorous and
Ethical studies.
- Stress the value of research in contributing to the advancement of knowledge and addressing
important societal issues.
11. Proposal Writing
Welcome to the world of proposal writing! In this concise booklet, you'll gain the essential
knowledge and step-by-step guidance to successful proposal writing. Discover the purpose,
components, and significance of proposals while learning practical tips and best practices.
12. Questionnaire
Welcome to questionnaire design! This guide provides concise, step-by-step instructions to
create effective surveys. Learn best practices, avoid common mistakes, and gain the skills to
design engaging questionnaires. From research objectives to question types,generating
valuable data for informed decision-making. Let's unlock the potential of your research
through impactful questionnaire design!"
13. Gantt Chart
"What is a Gantt Chart? Its Importance, Significance, and How to Develop One."
Additionally, we are excited to announce that soon we will be publishing another booklet
specifically focused on manuscript writing and publication. In this upcoming publication, we will
discuss in-depth topics such as writing an impactful abstract, structuring your manuscript
effectively, selecting the right research journal, and navigating the publication process. This
resource will provide valuable insights and practical advice to help you effectively communicate
your research findings to the academic community and increase your chances of publication
success.
We hope that this booklet, along with the forthcoming publication on manuscript writing and
publication, will serve as indispensable resources on your research journey, enabling you to
conduct high-quality research and effectively disseminate your findings to the broader scientific
community.
14
TITLE: THE EMERGENCE OF RESEARCH AND ITS REWARDS
Introduction:
Research is the product of human cognition, driven by the exploration of possibilities beyond the
boundaries of certainties. It is a fundamental process that leads us from the realm of “yes” or
“no” to the nuanced realm of “maybe.” This transformation in thinking allows us to challenge
preconceived notions and delve into the complexities of knowledge. This booklet examines the
relationship between research and knowledge, emphasizing the concept of justified true belief
and the rewards that research offers.
Section 1: Justified True Belief as the Foundation of Knowledge
Knowledge
Traditionally defined as justified true belief, forms the basis of our understanding. This
framework acknowledges that knowledge must be well-founded and supported by valid
justifications to attain the status of truth. The epistemological framework is sued to acquire valid
knowledge.
Section 2: Research as the Means to Expand Knowledge
2.1 Research as an Extension of Knowledge:
Research serves as a vehicle for the expansion of knowledge beyond existing boundaries. It acts
as a catalyst for the progression from established truths to more refined and comprehensive
understandings.
2.2 The Role of Experience, Study, and Investigation:
Through the amalgamation of personal experience, dedicated study, and rigorous investigation,
researchers gain valuable insights that contribute to the advancement of knowledge. By
exploring uncharted territories, researchers can confirm or refute existing beliefs, gradually
building a more accurate and nuanced understanding of various phenomena.
2.3 The Justification of Belief through Research:
Research plays a crucial role in the justification of beliefs. By subjecting hypotheses and
assumptions to systematic investigation and analysis, researchers can validate or reject them
based on empirical evidence and logical reasoning. This process ensures that beliefs are
grounded in sound and reliable foundations.
Section 3: The Rewards of Research
3.1 Intellectual Fulfillment:
Research offers a profound sense of satisfaction and intellectual fulfillment. The pursuit of
knowledge and the discovery of new insights provide researchers with a deep sense of
accomplishment, expanding their intellectual horizons and fostering personal growth.
15
3.2 The “AAHH” Moment:
A notable reward of research is the euphoric “AAHH” moment. It represents the exhilaration
experienced when a researcher successfully unveils a significant finding or solves a long-
standing problem. This moment of revelation not only confirms the value of research but also
motivates further exploration and innovation.
Conclusion:
Research emerges from the transition from binary thinking to a realm of possibilities, and it plays
a pivotal role in the growth and refinement of knowledge. By upholding the principles of
justified true belief, researchers strive to uncover the truth through experience, study, and
investigation. The rewards of research, including intellectual fulfillment and the exhilarating
“AAHH” moment, fuel the continuous pursuit of knowledge and contribute to the advancement
of society as a whole.
16
TITLE: UNDERSTANDING RESEARCH: A SYSTEMATIC PURSUIT
OF KNOWLEDGE
Introduction:
Research is a formal and systematic endeavor aimed at expanding the existing body of
knowledge and devising new applications. It encompasses a process of data collection, analysis,
and interpretation with the ultimate goal of finding solutions to problems. The results of research
are made available to the wider community, fostering the growth and dissemination of
knowledge. This booklet explores the different types of research, namely quantitative,
qualitative, and mixed methods, highlighting their characteristics and applications in various
fields, with a particular focus on clinical research.
Section 1: Defining Research
The Quest for Knowledge:
Research is a formal and systematic undertaking driven by the pursuit of knowledge. It
involves rigorous investigation, analysis, and exploration of various subjects or phenomena
to uncover new insights and deepen our understanding.
Expanding the Stock of Knowledge:
A key objective of research is to contribute to the expansion of the existing stock of
knowledge. By generating the latest information, theories, and concepts, research enriches
our collective understanding and opens doors to the development of innovative applications
in various domains.
Section 2: Types of Research
2.1 Quantitative Research:
Quantitative research relies on numerical data and statistical analysis to investigate and explore
relationships, patterns, and trends. It often involves large-scale studies, surveys, or experiments,
providing a structured and measurable approach to gather information. Quantitative research
plays a significant role in clinical studies, offering insights into treatment effectiveness, patient
outcomes, and disease prevalence. Example: Study examining the relationship between sleep
duration and academic performance among college students.
2.2 Qualitative Research:
Qualitative research focuses on exploring and understanding the subjective experiences, beliefs,
attitudes, and behaviors of individuals or groups. It employs methods such as interviews,
observations, and analysis of textual or visual data to generate rich and context-dependent
17
insights. Qualitative research is often conducted within specific communities or populations,
allowing for an in-depth exploration of their unique perspectives and experiences.
Example: Study exploring the experiences of immigrants transitioning to a new country.
2.3 Mixed Methods Research:
Mixed methods research integrates both quantitative and qualitative approaches within a single
study. This methodological approach enables researchers to use the strengths of both
methodologies, combining statistical analysis with contextual understanding. By employing
mixed methods, researchers can triangulate findings, provide comprehensive explanations, and
gain a more holistic understanding of complex phenomena. Example: A study on the
effectiveness of a teacher training program on student engagement in a primary school.
Section 3: Applications and Comparisons
3.1 Clinical Research and Quantitative Emphasis:
Clinical research, as a specialized domain, heavily relies on quantitative methods. The objective
is to evaluate the efficacy of treatments, assess medical interventions, and quantify patient
outcomes. The emphasis on numerical data and statistical analysis enables researchers to draw
evidence-based conclusions and guide medical decision-making.
3.2 Endogeneity in Qualitative Research:
Qualitative research acknowledges the importance of context and aims to capture the unique
experiences of individuals or groups within a specific setting. This endogenous approach
recognizes the inherent subjectivity and seeks to explore the perspectives of the participants to
gain a deeper understanding of their lived realities.
3.3 Comparative Analysis in Quantitative Research:
Quantitative research allows for the comparison of studies conducted by separate groups on the
same topic. By employing standardized methodologies and statistical analyses, researchers can
objectively assess and compare findings to identify consistencies or inconsistencies. This
comparative approach enhances the validity and reliability of research outcomes.
Conclusion:
Research is a systematic and formal process that expands the stock of knowledge, generates
innovative applications, and provides solutions to problems. The distinction between
quantitative, qualitative, and mixed methods research enables researchers to approach
investigations from different perspectives and address complex phenomena comprehensively. By
embracing the diverse methodologies available, researchers can contribute to a multidimensional
understanding of the world and promote advancements in various fields of study.
18
TITLE: SELECTING AN AREA OF INTEREST FOR RESEARCH:
CONSIDERATIONS AND CRITERIA
Introduction:
Choosing a suitable area of interest for research is a critical step that sets the foundation for
successful academic exploration. The selected area should have broad relevance, offer multiple
outcomes for extensive research output, and meet certain criteria to ensure its acceptability. This
booklet explores the criteria for selecting an area of interest, emphasizing factors such as
relevance, novelty, acceptability, cost-effectiveness, and ethical considerations. Additionally, it
proposes a committee-based evaluation process that determines the acceptance of research
proposals based on a score threshold.
Section 1: Broadness and Multiple Outcomes
The Significance of a Broad Area of Interest:
Selecting a broad area of interest: Such as diabetes or myocardial infarction, provides ample
opportunities for in-depth exploration and multiple research outcomes. This approach allows
researchers to delve into various aspects, subtopics, or associated factors within the chosen area,
thereby enabling the production of multiple papers or articles.
Section 2: Criteria for Choosing an Area of Interest
2.1 Relevance:
Relevance is a crucial criterion for selecting an area of interest. Researchers should consider the
practical importance and applicability of their chosen area, such as investigating the prevalence
and impact of dengue in Pakistan. The chosen topic should address a current issue or problem
that has implications for society, healthcare, or a specific field of study.
2.2 Novelty:
Identifying a research gap is essential in selecting an area of interest. Researchers should explore
existing literature to determine if there is a dearth of studies or unexplored aspects within their
chosen field. By focusing on uncharted territories or unresolved questions, researchers can
contribute new insights and knowledge to the existing body of literature.
2.3 Acceptability:
The chosen area of interest should be phrased in a positive manner to ensure acceptability.
Avoiding negative connotations, such as phrases like “incompatibility of teachers in our
university,” ensures a more constructive and unbiased approach. Framing the research question
19
or topic in a positive light facilitates a more favorable reception by the academic community and
enhances the potential for collaboration and support.
2.4 Cost-effectiveness:
Researchers should consider the cost implications associated with their chosen area of interest. It
is important to evaluate the feasibility of conducting research within the available resources,
including funding, equipment, and personnel. Selecting an area that aligns with available
resources ensures that the research can be conducted efficiently and effectively.
2.5 Ethical Issues:
Ethical considerations play a crucial role in selecting an area of interest. Researchers must assess
whether their proposed research complies with ethical guidelines and safeguards the rights and
well-being of participants. Evaluating potential ethical concerns and ensuring appropriate
measures for informed consent, confidentiality, and data protection are in place are essential
aspects of responsible research.
Section 3: Proposal Evaluation Process
3.1 Committee-Based Evaluation:
A committee-based evaluation process can be employed to assess the acceptance of research
proposals. The committee evaluates the proposals based on predetermined criteria and assigns
scores to each criterion. The total score required for proposal acceptance should be set at a
threshold, such as 70% of the total score, to ensure that proposals meet the necessary standards
for research approval.
Conclusion:
Selecting an area of interest for research requires careful consideration and adherence to specific
criteria. A broad area of interest offers opportunities for extensive exploration and multiple
research outcomes. Relevance, novelty, acceptability, cost-effectiveness, and ethical
considerations serve as crucial criteria when choosing an area of interest. By employing a
committee-based evaluation process, research proposals can be rigorously assessed, ensuring that
only high-quality and impactful studies are approved for further investigation.
20
TITLE: RESEARCH OBJECTIVES: SETTING SPECIFIC AND
MEASURABLE INTENTIONS
Introduction:
Research objectives play a crucial role in providing clear direction and focus to a research study.
By establishing specific objectives, researchers can articulate their intentions in a measurable and
actionable manner. Objective start with “TO” (to find out, to calculate, to compare)
Subjective Elements:
Subjective elements in research objectives are influenced by individual perceptions,
interpretations, or knowledge. These elements may vary among researchers or participants and
can introduce bias or subjective interpretations. For example, referring to an abdominal swelling
as "huge" represents a subjective element that may differ depending on the observer's
perspective.
Objective Elements:
Objective elements within research objectives are universally applicable and can be observed or
measured consistently. These elements provide a common ground for researchers to assess and
compare findings. For example, stating an objective to determine the size of a swelling on the
right hypochondrium as 10 by 10 represents an objective element that is measurable and
reproducible.
Section 1: The Significance of Specific Research Objectives
1.1 Defining Research Objectives:
Research objectives outline the specific aims and goals of a study. These objectives guide the
research process and help researchers stay focused on achieving measurable outcomes.
1.2 Clarity through Specificity:
Specific research objectives provide clarity by clearly defining the scope and purpose of the
study. They enable researchers to articulate their intentions in a precise and concise manner,
facilitating effective planning and execution of the research.
For example: The objective of this research study is to investigate the prevalence and risk factors
associated with a (specific medical) diabetic mellitus condition among smoker (a selected
population.)
21
Section 2: The Role of Objective Elements in Research Objectives
2.1 The Importance of Objective Elements or Phrases:
Research objectives should employ objective Elements or phrases that are measurable,
reproducible, and comparable. These terms enable researchers to establish clear parameters for
data collection, analysis, and interpretation.
2.2 Action Words for Measurability:
Research objectives should begin with action words that emphasize the measurable aspect of the
study. Starting objectives with phrases like "to find out," "to calculate," or "to compare" sets the
stage for specific and measurable outcomes.
2.3 Measurability, Reproducibility, and Comparability:
Objective words in research objectives ensure that the intended outcomes can be measured,
reproduced, and compared across different contexts. This allows for rigorous evaluation and the
establishment of scientific validity.
Conclusion:
Research objectives form a vital component of any study, outlining specific intentions and
guiding the research process. By utilizing objective Elements or phrases, researchers can ensure
the clarity, measurability, reproducibility, and comparability of their objectives. The distinction
between objective and subjective elements within research objectives emphasizes the importance
of establishing measurable criteria that can be universally applied and evaluated. By setting clear
and specific research objectives, researchers enhance the validity, reliability, and impact of their
studies.
22
TITLE: OPERATIONAL DEFINITION: ENHANCING CLARITY
AND PRECISION IN RESEARCH
Introduction:
Operational definition is a critical aspect of research that ensures clarity and precision in the use
of words or terms. It serves the purpose of explaining or defining specific words or variables
within the research objectives. Here we highlight the significance of operational definition in
research, emphasizing its role in providing clear and unambiguous explanations. Furthermore, it
underscores the understanding that data collection involves variables, and operational definitions
are essential in establishing the parameters of these variables.
For example: If we use the term 'diabetes mellitus' in our objective, we need to explain what
diabetes mellitus is, and if there is any cutoff value, we must mention it.
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels
(hyperglycemia) resulting from either insufficient insulin production by the pancreas or the
body's inability to effectively utilize insulin.
To diagnose an individual with diabetes, a fasting blood sugar level of 126 mg/dL (7.0 mmol/L)
or higher on two separate occasions is typically considered the cutoff value. This criterion helps
identify sustained hyperglycemia, indicating the presence of diabetes.
Section 1: Defining Operational Definition
1.1 Clarifying Terms and Variables:
Operational definition refers to the process of providing explicit explanations or definitions for
words, terms, or variables used within a research study. It serves to minimize ambiguity and
promote consistent interpretations among researchers.
1.2 Enhancing Clarity and Precision:
The purpose of operational definition is to enhance clarity and precision in research. By precisely
defining key concepts, terms, or variables, researchers establish a common understanding and
facilitate accurate communication throughout the study.
Section 2: Operational Definition as a Variable of Study
2.1 The Nature of Data Collection:
Data collection is an integral part of research, involving the gathering of information or
observations related to the study's objectives. Within this process, data itself can be considered a
variable that requires operational definition.
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2.2 Defining Data Variables:
Operational definitions play a crucial role in establishing the parameters of data variables.
Researchers must clearly define the nature, type, and characteristics of the data they collect. By
doing so, they ensure consistency in the measurement and interpretation of data across the study.
Section 3: Eliminating Ambiguity through Operational Definition
3.1 Ambiguity in Research:
Ambiguity can arise when terms or variables are loosely defined or open to multiple
interpretations. This can lead to confusion, inconsistency, and potential biases in the research
process and outcomes.
Ambiguous Objective: "To study the effects of a new drug on patient outcomes."
Revised Objective: "To assess the efficacy and safety of Drug X in reducing symptom severity
and improving quality of life in patients with moderate to severe asthma through a randomized
controlled trial."
In the revised objective, the ambiguity is addressed by specifying the drug under investigation
(Drug X), the targeted patient population (those with moderate to severe asthma), and the
specific outcomes of interest (reducing symptom severity and improving quality of life). This
clarification provides a clear focus for the research study.
3.2 The Role of Operational Definition:
Operational definition acts as a safeguard against ambiguity by providing explicit explanations or
definitions. By precisely describing the meaning, scope, and measurement of key terms or
variables, researchers eliminate potential confusion and ensure that their study is clear and
unambiguous.
Conclusion:
Operational definition is an essential tool in research, enabling researchers to enhance clarity,
precision, and consistency in their work. By explicitly defining terms, variables, and data
parameters, researchers establish a common understanding and eliminate ambiguity. This
promotes accurate communication, reliable interpretation, and valid conclusions. Emphasizing
the importance of operational definition contributes to the overall quality and rigor of research,
ultimately enhancing its impact and value.
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TITLE: LITERATURE REVIEW: A COMPREHENSIVE EXAMINATION
OF KEY SOURCES
Introduction:
The literature review is a critical component of the research process, providing a comprehensive
examination of existing knowledge and research on a specific topic. Here we highlight the
importance of utilizing relevant keywords during the literature review, along with recommended
sources such as Pub Med and the National Library of Medicine. Furthermore, it acknowledges
that the literature review phase often requires a significant time investment, typically around two
weeks, and emphasizes the potential for refining the area of interest, objectives, and operational
definitions based on the review's findings.
Section 1: Keyword Utilization in Literature Review
1.1 Importance of Keywords:
Keywords serve as essential tools in the literature review process, enabling researchers to locate
relevant studies and articles. They facilitate effective searching, both by others seeking to find
the researcher's study and by the researcher when studying other research.
1.2 Keyword Usage:
During the literature review, researchers should carefully consider the keywords used by others
to locate their study and incorporate those keywords into their own searches. This approach
ensures comprehensive coverage of relevant literature and allows for a more comprehensive
understanding of the topic.
Section 2: Recommended Sources for Literature Review
➢ Pub Med:
Pub Med, a widely recognized and authoritative database, offers an extensive collection
of biomedical literature. Researchers can access a wealth of scholarly articles, journals,
and research studies related to their area of interest. Pub Med serves as a valuable
resource for conducting comprehensive literature reviews.
➢ National Institute of Health National Library of Medicine:
The National Institute of Health's National Library of Medicine provides access to an
extensive array of biomedical literature and research resources. Its databases, such as
PubMed Central, MEDLINE, and other specialized collections, offer researchers a wealth
of information for their literature reviews.
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➢ Academic Databases:
Academic Databases Access scholarly databases such as Pub Med, Google Scholar,
Scopus, and Web of Science. These platforms provide access to a wide range of peer-
reviewed journal articles, conference papers, theses, and dissertations.
➢ Academic Journals:
Academic Journals Explore relevant journals in your field of study. Look for reputable
journals that publish high-quality research articles and review papers. Examples include
New England Journal of Medicine, The Lancet, Journal of the American Medical
Association (JAMA), and British Medical Journal (BMJ).
➢ Books and E-books:
Books and E-books Consult textbooks, monographs, and reference books written by
experts in the field. Books often provide in-depth coverage of specific topics and can
provide a historical context or theoretical framework for your research.
➢ Government and Institutional Reports:
Government and Institutional Reports Check government reports, policy documents, and
publications from reputable institutions such as the World Health Organization (WHO),
Centers for Disease Control and Prevention (CDC), National Institutes of Health (NIH),
United Nation (UN), United Nation International Children’s Emergency Fund (UNICEF)
and other relevant governmental or non-governmental organizations.
➢ Professional Associations and Organizations:
Professional Associations and Organizations Visit the websites of professional
associations and organizations related to your research topic. These organizations often
publish journals, reports, and guidelines that can provide valuable insights and current
research in the field.
➢ Theses and Dissertations:
Theses and Dissertations Explore relevant theses and dissertations in your field, which
are often available through university libraries or digital repositories. These works can
provide comprehensive reviews of the literature and may highlight gaps in research that
can guide your own study.
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➢ Conference Proceedings:
Conference Proceedings Check conference proceedings in your field, as they often
contain cutting-edge research and preliminary findings. Some conferences also publish
full papers or abstracts that can be valuable for your literature review.
Section 3: Time Investment for Literature Review
3.1 Duration of Literature Review:
The literature review phase of research typically requires a significant time investment.
Researchers should allocate a minimum of 15 days, or approximately two weeks, to thoroughly
review and analyze the relevant literature. This timeframe allows for a comprehensive
examination of the existing knowledge base and facilitates the identification of research gaps and
potential revisions to the research plan.
Section 4: Potential for Refinement Based on Literature Review Findings
4.1 Adaptability of Area of Interest, Objectives, and Operational Definitions:
The literature review phase offers researchers the opportunity to gain valuable insights from
existing studies, potentially leading to adjustments in their area of interest, research objectives,
and operational definitions. New information and perspectives obtained through the review
process may prompt researchers to refine and realign their research plan for enhanced relevance
and impact.
4.2 Critical Decision-Making Point:
Once the literature review is completed and revisions are made to the area of interest, objectives,
and operational definitions, researchers reach a critical decision-making point. At this stage,
further adjustments may be difficult or impractical. Therefore, thorough consideration and
consultation with advisors or peers are essential to ensure a well-informed and justified research
direction.
Conclusion:
The literature review is a crucial phase in the research process, involving the utilization of
relevant keywords and trusted sources such as PubMed and the National Library of Medicine.
Allocating adequate time for the literature review phase, typically around two weeks, allows for
a comprehensive examination of existing knowledge. Researchers should remain open to the
potential refinement of their area of interest, objectives, and operational definitions based on the
findings of the literature review. Careful attention to this process strengthens the research
foundation, enhances the quality of the study, and contributes to the advancement of knowledge
in the field.
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TITLE: CONDUCTING RESEARCH: A COMPREHENSIVE GUIDE
Introduction:
Conducting research involves a systematic approach to investigating a specific topic, identifying
variables, selecting the study population, and defining research objectives. This booklet provides
a formal and beautified guide on how to conduct research effectively. It emphasizes the
importance of understanding dependent and independent variables, the selection of the study
population, and the consideration of confounding variables when formulating research
objectives. Additionally, the influence of confounding variables on study design and the
limitations they may impose are discussed.
Section 1: Identifying Variables in the Study
1.1 Variable Identification:
Variables form the foundation of research and can be categorized as dependent or independent.
In the example of studying the relationship between pregnancy and anemia, pregnancy is the
independent variable, while anemia is the dependent variable. Anemia is influenced by
pregnancy, making it dependent, whereas pregnancy itself is not affected by anemia, making it
independent.
Section 2: Selecting the Study Population
2.1 Defining the Study Population:
The selection of an appropriate study population is crucial for obtaining meaningful results.
Researchers should clearly define the characteristics and criteria for selecting the study
population to ensure it represents the target population accurately.
Inclusion and exclusion criteria:
Inclusion criteria: Clearly state and justify the specific characteristics that qualify individuals for
participation in the study. Avoid overly restrictive criteria to ensure the generalizability of
findings.
For example:
1. Age: Participants aged 40-65 years.
2. Diabetes Diagnosis: Participants diagnosed with type 2 diabetes.
3. Smoking Status: Current smokers or individuals who have quit smoking within the past
five years.
4. Health Condition: Participants with stable medical conditions and able to provide informed
consent.
Exclusion criteria: Clearly state and justify the specific characteristics that disqualify individuals
from participating in the study. Be cautious of potential biases and carefully consider the balance
between participant safety and sample representativeness.
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For example:
1. Age: Participants below 40 years or above 65 years.
2. Diabetes Type: Participants with type 1 diabetes or other forms of diabetes.
3. Smoking Status: Non-smokers and individuals who quit smoking more than five years ago.
4. Unstable Health Condition: Participants with uncontrolled or severe co-morbidities that
may confound the study outcomes.
5. Pregnancy: Pregnant or breastfeeding individuals due to potential effects on the study
parameters.
Transparency: Clearly communicate the criteria to ensure transparency and reproducibility of the
study.
Consistency: Apply the criteria consistently to all participants throughout the study.
Ethical considerations: Address ethical implications, such as protecting vulnerable populations
and managing conflicts of interest.
Justification: Provide a clear rationale for each criterion to demonstrate its relevance and
importance to the study.
Section 3: Understanding Confounding Variables
3.1 Confounding Variables:
Confounding variables are factors that can affect the study but are not the variables under
investigation. They introduce a relationship between the dependent and independent variables,
potentially distorting or influencing the observed cause-and-effect relationship. Inclusion and
exclusion criteria should be carefully considered to address confounding variables effectively.
Confounding Variable: Body Mass Index (BMI)
Confounding Variable: BMI is a confounding variable that can potentially affect the relationship
between diabetes, smoking, and the study outcomes. Higher BMI is associated with an increased
risk of both diabetes and certain smoking-related health issues. If the distribution of BMI differs
significantly between the included and excluded participants, it can introduce bias and confound
the study results. To mitigate this, researchers may consider stratifying participants based on
BMI or including it as a covariate in the analysis to account for its potential influence.
3.2 Limitations and Unavoidable Confounding Factors:
While researchers strive to eliminate confounding variables, some factors may be inherently
difficult or impossible to control. These limitations can impact the study's validity and may limit
the extent to which the research findings can be generalized.
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Non-Avoidable Confounding Factor: Socioeconomic Status (SES)
Non-Avoidable Confounding Factor: Socioeconomic status (SES) is a non-avoidable
confounding factor that may influence both diabetes and smoking behaviors. Individuals with
lower SES may have a higher prevalence of diabetes and a higher likelihood of being smokers
due to various factors such as limited access to healthcare, educational disparities, and stress.
Although it is challenging to completely eliminate the influence of SES, researchers can attempt
to minimize its impact by collecting and analyzing data on SES indicators, such as education
level or income, and adjusting for them in statistical analyses.
Non-avoidable confounding factors pose challenges in research studies as they cannot be directly
controlled or eliminated. However, by carefully collecting and analyzing relevant data,
researchers can account for these factors to the best of their ability and interpret study results in
consideration of their potential influence.
Section 4: Incorporating Confounding Factors into Objective Formulation
4.1 Consideration of Confounding Factors:
When phrasing research objectives, it is crucial to keep confounding factors in mind. Objectives
should be formulated in a manner that acknowledges and accounts for potential confounding
variables, ensuring that the research design and data analysis adequately address these factors.
Example: Myocardial Infarction (MI) in Patients with a Low-Fat Diet
In the case of studying MI in patients who do not consume fat, potential confounding factors
such as age, smoking habits, and pre-existing medical conditions should be considered. The
objective formulation should explicitly address these confounding variables to ensure accurate
and reliable research outcomes.
Conclusion:
Conducting research involves a systematic approach that encompasses variable identification,
study population selection, and objective formulation. Understanding the distinction between
dependent and independent variables, as well as the influence of confounding variables, is
essential for designing robust research studies. By considering and accounting for confounding
factors, researchers can enhance the validity and reliability of their findings, contributing to the
advancement of knowledge in their respective fields.
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TITLE: STUDY DESIGN: A COMPREHENSIVE OVERVIEW
Introduction:
Selecting an appropriate study design is crucial for conducting rigorous and informative
research. This booklet provides overview of different study designs, specifically focusing on
descriptive study designs. These designs include case reports, case series, and cross-sectional
studies, each serving unique purposes in investigating specific research questions. Understanding
these study designs aids researchers in choosing the most suitable approach for their research
objectives.
Section 1: Descriptive Study Designs
1.1 Case Report:
A case report is a descriptive study design based on a single case that presents a unique or rare
condition or outcome. It provides an in-depth analysis of an individual case, such as a case of
lithopedion, shedding light on its clinical presentation, diagnostic process, and treatment. Case
reports contribute valuable insights into understanding uncommon conditions or treatments and
can serve as a foundation for further research.
1.2 Case Series:
A case series is a descriptive study design that focuses on a collection of similar cases. It
involves studying multiple cases of a particular condition, such as cases of lithopedion in
different hospitals. Case series provide a broader perspective by analyzing similarities and
variations across multiple cases, allowing for the identification of patterns, trends, or common
characteristics.
1.3 Cross-sectional Study:
A cross-sectional study is a descriptive study design that provides a snapshot of a specific
population at a given time. It aims to determine the prevalence or presence of certain factors or
conditions within a defined population. Cross-sectional studies are particularly useful for
estimating the prevalence of a disease or assessing the distribution of risk factors. However, they
do not establish causality or provide information on the incidence or temporal relationships
between variables.
Section 2: Advantages and Considerations
2.1 Advantages:
Descriptive study designs offer several advantages. Case reports provide detailed information
about rare or unique cases, contributing to medical knowledge and raising awareness. Case series
offer insights into patterns and commonalities across multiple cases, aiding in the identification
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of potential risk factors or treatment outcomes. Cross-sectional studies provide valuable
prevalence data and facilitate the identification of potential associations.
2.2 Considerations:
While descriptive study designs are valuable, they have limitations. Case reports and case series
lack comparison groups, limiting their ability to establish causality or draw definitive
conclusions. Cross-sectional studies provide a snapshot of data at a specific time, but they do not
account for temporal relationships or establish cause-and-effect relationships.
Conclusion:
Descriptive study designs, including case reports, case series, and cross-sectional studies, play an
essential role in research. They provide valuable insights into unique cases, patterns across
multiple cases, and the prevalence of certain conditions or factors. Understanding the advantages
and considerations of each design aids researchers in selecting the most appropriate approach to
address their research questions and contributes to the advancement of knowledge in their
respective fields.
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TITLE: ANALYTICS: OBSERVATIONAL AND EXPERIMENTAL
STUDY APPROACHES
Introduction:
Analytics plays a crucial role in research, providing valuable insights into relationships,
outcomes, and interventions. Here we focus on two key components of analytics: observational
studies and experimental studies. Observational studies encompass cohort studies and case-
control studies, while experimental studies involve interventions and comparisons between
different groups or conditions.
Section 1: Observational Studies
1.1 Cohort Study:
A cohort study involves a group of individuals with similar characteristics who are followed over
time to examine the development of specific outcomes or conditions. It can be conducted in a
prospective manner, where data is collected moving forward, or in a retrospective manner, where
data is collected looking backward. Cohort studies provide valuable information on the natural
history, risk factors, and outcomes of a particular condition.
1.2 Case-Control Study:
A case-control study selects a population based on a specific disease or outcome and compares
individuals who have developed the disease (cases) with those who have not (controls). By
examining past exposures or characteristics, researchers can determine potential risk factors or
associations with the development of the disease. Case-control studies are useful when studying
rare conditions or outcomes.
Section 2: Experimental Studies
2.1 Intervention:
Experimental studies involve interventions or treatments that are administered to participants.
Researchers compare the outcomes or responses between different groups or conditions to
determine the effectiveness or impact of the intervention. Experimental studies provide a
controlled environment to assess causality and establish the efficacy of interventions.
2.2 Comparison:
In experimental studies, researchers typically compare two or more groups or conditions. These
comparisons can involve different treatments, interventions, dosages, or control groups. By
comparing the outcomes between groups, researchers can evaluate the relative effectiveness or
differences in response.
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Conclusion:
Analytics in research includes both observational studies and experimental studies.
Observational studies, such as cohort studies and case-control studies, provide insights into
natural history, risk factors, and associations of specific conditions. Experimental studies involve
interventions and comparisons between different groups or conditions to assess efficacy and
causality. By employing a combination of observational and experimental approaches,
researchers can gain a comprehensive understanding of relationships, outcomes, and
interventions, advancing knowledge in their respective fields.
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TITLE: SAMPLING METHODS: ENSURING REPRESENTATIVE
DATA COLLECTION
Introduction:
Sampling is a critical aspect of research, as it involves selecting a subset of individuals from a
larger population to gather data. In this booklet we discusses various sampling methods, and
calculating sampling size that researchers can employ to ensure representative data collection.
These methods can be categorized into non-probability sampling, where not everyone has an
equal chance of participation, and probability sampling, where everyone has an equal chance of
participation.
Section 1: Non-Probability Sampling Methods
1.1 Consecutive Sampling:
Consecutive sampling involves selecting participants in a continuous sequence, such as including
the first 5 subjects from a total of 10. This method may introduce bias if the order of selection
affects the sample's representativeness.
1.2 Purposive Sampling:
Purposive sampling involves selecting participants based on specific criteria or characteristics
that align with the research objectives. Researchers intentionally choose individuals who possess
the desired qualities to provide in-depth insights into the research topic.
1.3 Convenience Sampling:
Convenience sampling involves selecting participants based on their easy accessibility or
availability to the researcher. This method is convenient but may introduce bias due to the non-
random selection of participants.
Section 2: Probability Sampling Methods
2.1 Simple Random Sampling:
Simple random sampling involves randomly selecting individuals from the population, giving
each person an equal chance of being included. This method is commonly used for small
populations and can be conducted using techniques like balloting or random number generation.
2.2 Systematic Sampling:
Systematic sampling involves selecting participants at fixed intervals from a larger population.
The total population is divided by the desired sample size, and participants are selected based on
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a pre-determined pattern, such as every nth person on a list. This method ensures a representative
sample and is useful for large populations.
2.3 Stratified Sampling:
Stratified sampling involves dividing the population into distinct subgroups or strata based on
specific characteristics. Researchers then randomly select participants from each stratum in
proportion to their representation in the overall population. This method ensures adequate
representation of each subgroup and is useful when certain subgroups have unique characteristics
or differences.
2.4 Cluster Sampling:
Cluster sampling involves selecting groups or clusters of participants rather than individual
participants. Clusters can be geographical regions, schools, or organizations. Researchers
randomly select clusters and then collect data from all individuals within the selected clusters.
This method is efficient when participants within clusters share similar characteristics.
Conclusion:
Choosing an appropriate sampling method is essential to ensure representative data collection in
research. Non-probability sampling methods, such as consecutive, purposive, and convenience
sampling, offer convenience but may introduce bias. Probability sampling methods, including
simple random sampling, systematic sampling, stratified sampling, and cluster sampling, provide
more reliable and representative results. Researchers should carefully consider the characteristics
of their population and research objectives when selecting the most appropriate sampling method
for their study.
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TITLE: DATA COLLECTION METHODS: QUESTIONNAIRES,
SURVEYS, AND FOCUS GROUP DISCUSSIONS/INTERVIEWS
Introduction:
Data collection is a crucial step in research, allowing researchers to gather information and
insights from participants. There are three commonly used data collection methods:
questionnaires, surveys, and focus group discussions/interviews. Each method has its unique
characteristics and suitability for different types of studies, whether quantitative or qualitative.
Section 1: Questionnaires
1.1 Definition and Purpose:
Questionnaires involve presenting a set of structured questions to participants, typically in a
written format. They are designed to collect quantitative data and gather information directly
from the participants themselves.
1.2 Limitations:
Questionnaires have some limitations. They heavily rely on self-reporting, which may introduce
response bias or inaccuracies. Participants' interpretations of the questions and their willingness
to disclose certain information can also impact the quality of the data collected.
Section 2: Surveys
2.1 Definition and Purpose:
Surveys involve direct interaction between the researcher and the participants. Researchers
administer a series of pre-designed questions to gather quantitative data, often using various data
collection tools such as interviews, telephone calls, or online platforms.
2.2 Implementation and Benefits:
Surveys allow researchers to collect data in a controlled manner and clarify any questions
participants may have. They provide a higher level of researcher control compared to
questionnaires. Surveys are particularly useful for obtaining numerical data and identifying
patterns or trends in large populations.
Section 3: Focus Group Discussions/Interviews
3.1 Definition and Purpose:
Focus group discussions/interviews involve bringing together a small group of individuals or
conducting individual interviews to gather qualitative data. Researchers facilitate discussions or
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conduct interviews to explore participants' perspectives, experiences, and opinions on a specific
topic.
3.2 Implementation and Benefits:
Focus group discussions/interviews provide rich and in-depth qualitative data. They offer a
deeper understanding of participants' thoughts, emotions, and motivations. The interactive nature
of these methods allows for probing and follow-up questions, promoting insightful discussions
among participants.
Conclusion:
When planning data collection for a research study, researchers must carefully consider the
nature of the study and the type of data required. Questionnaires and surveys are effective tools
for collecting quantitative data from participants, while focus group discussions/interviews
provide valuable qualitative insights. By selecting the appropriate data collection method,
researchers can ensure they gather relevant and reliable data to support their research objectives
and contribute to the advancement of knowledge in their field.
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TITLE: DATA PREPARATION AND SUMMARIZATION IN
RESEARCH
Introduction:
Data preparation and summarization play a crucial role in research, allowing researchers to
analyze and present their data effectively. In this booklet we explores various techniques for
preparing and summarizing data, including frequency tables, charts, graphs, and key statistical
measures such as mean, median, mode, range, variance, and standard deviation. Additionally, it
discusses the significance of the null hypothesis in research and the importance of considering
the p-value when testing hypotheses.
Section 1: Data Preparation
1.1 Representation of Data:
Data can be represented using different formats, such as frequency tables, charts, and graphs,
depending on the type of data and the purpose of analysis. These visual representations enhance
understanding and facilitate data interpretation.
Section 2: Data Summarization Measures
1) Mean:
The mean, also known as the average, is calculated by summing up all the values in a dataset and
dividing it by the total number of values. It represents the central tendency of the data.
Example: Consider a dataset of ages of five individuals: 25, 30, 35, 40, and 45. To find the mean,
add up all the values (25 + 30 + 35 + 40 + 45 = 175) and divide by the total number of values
(5). The mean age in this case is 35 (175 divided by 5).
2) Median:
The median represents the middle value in a dataset when the values are arranged in ascending or
descending order. If there is an even number of values, the median is calculated by taking the
average of the two middle values.
Example: Let's consider the dataset of ages again: 25, 30, 35, 40, and 45. When arranged in
ascending order, the middle value is 35. Therefore, the median age in this case is 35.
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3) Mode:
The mode is the value or values that appear most frequently in a dataset. It is not necessarily
unique and can have multiple modes or no mode at all.
Example: Suppose we have a dataset of test scores: 85, 90, 80, 85, 95. In this case, the mode is
85 since it appears twice, which is more frequently than any other value.
4) Range:
The range represents the difference between the highest and lowest values in a dataset. It
provides a measure of the spread or variability of the data.
Example: Consider a dataset of daily temperatures in degrees Celsius: 10, 15, 12, 18, 20. The
highest temperature is 20, and the lowest temperature is 10. Therefore, the range is 20 - 10 = 10
degrees Celsius.
5) Variance:
Variance measures the dispersion of data points from the mean. It quantifies the average squared
deviation from the mean, providing insight into the spread of data.
Example: Let's take the dataset of test scores again: 85, 90, 80, 85, 95. First, calculate the mean
(sum of all values divided by the total number of values) which is 87. Then, calculate the squared
difference between each score and the mean: (85-87)^2, (90-87)^2, (80-87)^2, (85-87)^2, (95-
87)^2. Find the average of these squared differences. The variance in this case is 16.8.
6) Standard Deviation:
The standard deviation is the square root of the variance. It provides a measure of how spread out
the values are in relation to the mean. The standard deviation is a widely used measure of
variability that indicates how much the data is dispersed around the mean. It provides a more
comprehensive understanding of data distribution compared to the variance.
Example: Using the same dataset of test scores, the variance was found to be 16.8. Taking the
square root of the variance, the standard deviation is approximately 4.1.
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Section 3: Null Hypothesis and p-value
3.1 Null Hypothesis:
The null hypothesis is a statement in research that assumes there is no significant relationship or
difference between variables. Researchers typically frame their research in null hypothesis form
as it is not possible to prove something with absolute certainty.
3.2 P-value and Hypothesis Testing:
The p-value represents the probability of obtaining results as extreme as the observed data,
assuming the null hypothesis is true. A p-value less than or equal to 0.05 (commonly referred to
as the significance level) is often used to reject the null hypothesis and support the alternative
hypothesis.
Conclusion:
Data preparation and summarization are essential steps in research, enabling researchers to
effectively analyze and present their findings. By representing data in frequency tables, charts,
and graphs, researchers can visually communicate patterns and trends. Summarization measures
such as mean, median, mode, range, variance, and standard deviation provide valuable insights
into the central tendency and variability of the data. Furthermore, the null hypothesis and the
consideration of the p-value play a critical role in hypothesis testing, ensuring robust and reliable
research conclusions.
THANK-YOU
Dr. Syed M Haroon
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Conceptual Breakdown
The epistemological framework
The epistemological framework refers to the philosophical perspective or approach to knowledge and
how it is acquired, validated, and understood. It provides the theoretical foundation and assumptions
that underlie a research study or inquiry. Epistemology deals with questions such as what constitutes
knowledge, how knowledge is acquired, and the criteria for validating knowledge claims.
In the context of research, the epistemological framework guides the researcher's understanding of how
knowledge is generated and the appropriate methods for investigating a research problem. It shapes the
researcher's stance on the nature of reality, the role of the researcher, and the relationship between the
researcher and the participants or subjects.
There are several common epistemological frameworks used in research, including:
1. Positivism: Positivism is based on the belief that knowledge can be objectively observed and
measured. It emphasizes the use of quantitative methods, experiments, and statistical analysis to gather
empirical evidence and establish causal relationships.
2. Interpretivism: Interpretivism focuses on understanding and interpreting the subjective meanings,
perspectives, and experiences of individuals. It emphasizes qualitative methods such as interviews,
observations, and textual analysis to capture the social and cultural contexts in which knowledge is
constructed.
3. Constructivism: Constructivism posits that knowledge is actively constructed by individuals through
their experiences, interactions, and interpretations. It recognizes the importance of multiple
perspectives and context in shaping understanding. Researchers employing constructivism often use
mixed methods, combining qualitative and quantitative approaches to capture both individual
experiences and broader patterns.
These epistemological frameworks influence the research design, data collection methods, data analysis
techniques, and the interpretation of findings. It is essential for researchers to explicitly state and justify
their chosen epistemological framework to ensure transparency and rigor in their study.
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TYPE OF RESEARCH:
Quantitative Research:
A quantitative research example would be a study examining the relationship between sleep duration and
academic performance among college students. Researchers might collect data from a large sample of students,
measuring their sleep duration using activity trackers and obtaining their academic grades from official records. By
analyzing the numerical data, they can determine if there is a correlation between sleep duration and academic
performance, allowing them to draw conclusions about the impact of sleep on students' grades.
Qualitative Research:
An example of qualitative research could be a study exploring the experiences of immigrants transitioning to a new
country. Researchers might conduct in-depth interviews with a small group of immigrants, asking open-ended
questions about their challenges, emotions, and cultural adaptation process. Through careful analysis of the
interview transcripts, they can gain a deeper understanding of the participants' perspectives, their unique
experiences, and the factors that influence their adjustment to the new environment.
Mixed Methods Research:
In a mixed methods research example, let's consider a study on the effectiveness of a teacher training program on
student engagement in a primary school. The researchers could administer surveys to both teachers and students
to collect quantitative data on various aspects of student engagement, such as attendance, participation, and
motivation. Additionally, they could conduct focus group discussions with teachers and students to gather
qualitative insights on their perceptions of the training program, the changes they observed, and the factors
influencing student engagement. By combining the quantitative survey data analysis with qualitative analysis of the
focus group discussions, the researchers can provide a more comprehensive understanding of the program's
impact and gather richer insights into the underlying mechanisms contributing to student engagement.
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Objective:
The objective of this research study is to determine which pain management approach, either Intervention A or
Intervention B, is more effective in reducing post-operative pain among patients who have undergone
appendectomy surgery.
In this example, the objective includes elements of measurability, reproducibility, and comparability:
1. Measurability: The objective aims to measure the effectiveness of pain management interventions in reducing
post-operative pain. The researchers will use pain rating scales, such as a 0-10 scale, where patients rate their pain
level, with 0 being no pain and 10 being the worst pain imaginable. By using this scale, the researchers can
quantitatively measure the level of pain experienced by patients in each intervention group.
2. Reproducibility: The objective suggests that the study can be reproduced by other researchers or healthcare
professionals to validate the findings. The researchers will provide clear details about the two pain management
approaches (Intervention A and Intervention B), including specific protocols and techniques used, so that other
healthcare providers can replicate the study in different hospitals or surgical centers.
3. Comparability: The objective aims to compare the effectiveness of Intervention A and Intervention B in reducing
post-operative pain. By comparing the pain levels reported by patients in each intervention group, the researchers
can determine which approach yields better pain control. This comparison helps healthcare professionals make
informed decisions about which pain management approach to use for patients undergoing appendectomy
surgery.
By incorporating these elements into the research objective, the study can be designed in a way that ensures the
results are easily measurable, reproducible, and comparable. This enhances the scientific validity of the research
and provides valuable insights for improving pain management strategies in the medical field.
44
Data Variables
Defining Data Variables is an important step in research, as it helps to clearly identify and describe the specific data
elements that will be collected and analyzed. Here are some examples of defining data variables in different
research contexts:
1. Example in Medical Research:
Variable: Blood Pressure
Definition: The systolic and diastolic pressure measurements, recorded in millimeters of mercury (mmHg),
representing the force exerted by blood against the arterial walls.
2. Example in Social Science Research:
Variable: Income
Definition: The amount of money earned by an individual or household over a specified period, typically measured
in a specific currency (e.g., US dollars, euros).
3. Example in Psychological Research:
Variable: Anxiety Level
Definition: A self-reported or observed measure of the individual's subjective experience of anxiety, often assessed
using standardized psychological scales or questionnaires.
4. Example in Educational Research:
Variable: Academic Performance
Definition: The measure of a student's achievement in academic subjects, usually represented by grades or test
scores obtained in specific courses or standardized assessments.
5. Example in Environmental Research:
Variable: Air Quality
Definition: The level of pollutants, such as particulate matter (PM2.5, PM10), nitrogen dioxide (NO2), or ozone
(O3), present in the air within a specific location, measured using specialized monitoring equipment.
When defining data variables, it is important to provide clear definitions that precisely describe the nature and
units of measurement for each variable. This ensures consistency and understanding among researchers and
enables accurate data collection and analysis.
45
Types of study designs:
OBSERVATIONAL STUDY
➢ Descriptive study
➢ Analytical Study
EXPERIMENTAL STUDY
Descriptive Study: Descriptive studies aim to describe and summarize the characteristics, behaviors, or
phenomena of interest within a population or sample. They focus on providing a comprehensive account of the
variables being studied without intervening or manipulating them. Descriptive studies answer questions such as
"What is happening?" or "What is the prevalence or distribution of a particular phenomenon?"
Example: A researcher conducts a cross-sectional survey to assess the prevalence of smoking among adults in a
specific community. The study involves collecting data from a sample of individuals through questionnaires or
interviews to determine the proportion of smokers in the population and their demographic characteristics.
Limitation: Descriptive studies do not establish causal relationships or determine cause-and-effect connections
between variables. They provide valuable information about the current status or prevalence but cannot explain
the reasons behind observed associations or changes.
➢ Descriptive studies
1. Case Series:
Case series involve the description and analysis of a series of cases with similar characteristics or outcomes. They
provide valuable insights into rare diseases or adverse effects of treatments. For example, a case series could
describe a series of patients presenting with a rare autoimmune disorder and provide information about their
clinical manifestations, treatment responses, and outcomes.
Limitations of case series:
- Lack of comparison group limits the ability to establish causality or draw definitive conclusions
- Subjective reporting and potential bias in selecting cases
- Limited generalizability due to the small sample size and potential for unique or atypical cases
2. Case Report:
A case report presents a detailed description of a single patient's diagnosis, treatment, and outcomes. They often
highlight unique or exceptional cases that contribute to medical knowledge. For example, a case report might
describe a patient who experienced a rare side effect of a medication.
Limitations of case reports:
- Lack of generalizability due to the focus on individual cases
- Subjective reporting and potential for bias in the interpretation of outcomes
- Limited ability to establish causality or draw broader conclusions
3. Cross-Sectional Study:
Cross-sectional studies collect data from a population at a single time point to determine the prevalence of
exposures and outcomes. This design helps identify associations but does not establish causality. For example, a
cross-sectional study could assess the prevalence of hypertension (outcome) in a specific population and examine
its association with obesity (exposure) based on measurements taken at a single time point.
46
Limitations of cross-sectional studies:
- Unable to establish temporal relationships or causality
- Susceptible to selection bias, as participants may not be representative of the entire population
- Limited ability to study rare outcomes or conditions due to the cross-sectional nature
➢ Analytical studies
2. Observational studies involve observing and collecting data on individuals or groups without intervening or
manipulating variables. These studies aim to analyze and understand relationships, associations, or patterns
between variables.
OR
Analytical studies involve analyzing and evaluating data to establish causal relationships or determine the effects
of interventions or exposures. These studies often compare groups or conditions to assess the impact of an
intervention, treatment, or exposure on outcomes of interest.
Example:1
A researcher conducts a cohort study to investigate the association between physical activity and the risk of
developing cardiovascular diseases. They follow a group of individuals over time, assessing their activity levels and
monitoring the occurrence of cardiovascular events.
Example:2
A researcher conducts a case-control study to investigate the association between pesticide exposure and the risk
of developing a specific type of cancer. They compare a group of individuals with the disease (cases) to a control
group without the disease, examining their history of pesticide exposure to determine if there is an increased risk.
Limitation:
- Analytical studies may face challenges in establishing causality due to confounding variables or biases. While they
can provide evidence of associations, other factors may contribute to the observed relationships.
1. Cohort Study:
Cohort studies involve following a group of individuals over time to assess the relationship between exposure (e.g.,
a risk factor) and outcomes (e.g., disease development). Participants are classified based on their exposure status
and followed prospectively. For example, a cohort study could investigate the association between smoking
(exposure) and the development of lung cancer (outcome) in a group of individuals.
Limitations of cohort studies:
- Time-consuming and expensive
- Attrition and loss to follow-up may affect the validity of results
- Difficult to control for all potential confounding factors
2. Case-Control Study:
Case-control studies are retrospective designs that compare individuals with a specific outcome (cases) to
individuals without the outcome (controls). Researchers identify past exposures or risk factors in both groups to
determine their association with the outcome. For example, a case-control study could examine the association
47
between pesticide exposure (exposure) and the development of Parkinson's disease (outcome) by comparing
individuals diagnosed with Parkinson's (cases) to individuals without the disease (controls).
Limitations of case-control studies:
- Recall bias, as participants may have difficulty accurately recalling past exposures
- Difficulty in establishing the temporal relationship between exposure and outcome
- Selection bias, as the selection of cases and controls may not be representative of the general population
➢ Experimental Study:
Experimental studies involve the deliberate manipulation of variables to evaluate cause-and-effect relationships.
Participants are randomly assigned to different groups, such as an experimental group receiving a treatment and a
control group receiving a placebo or standard treatment. For example, an experimental study could assess the
effectiveness of a new drug (treatment) compared to a placebo in reducing blood pressure (outcome) in individuals
with hypertension.
Limitations of experimental studies:
- Ethical considerations may limit the ability to randomly assign participants or manipulate certain variables
- Results may not fully reflect real-world conditions and may have limited
Randomized Controlled Trials (RCTs)
Randomized Controlled Trials (RCTs) are rigorous experimental study designs used to evaluate the efficacy or
effectiveness of interventions, treatments, or preventive measures. Here's an explanation of RCTs along with an
example and limitations:
1. RCT Definition:
A Randomized Controlled Trial (RCT) is a study design in which participants are randomly assigned to one of two or
more groups: an experimental group that receives the intervention or treatment being tested and a control group
that either receives a placebo or standard care. The random allocation helps ensure that the groups are
comparable, minimizing selection bias and confounding variables.
2. Example of RCT:
Let's consider an example of an RCT in the field of medicine. Suppose a new drug is developed to treat a specific
medical condition. To evaluate its effectiveness, an RCT is conducted. A group of participants with the medical
condition is randomly assigned to either the experimental group or the control group. The experimental group
receives the new drug, while the control group receives a placebo or an existing standard treatment. The
participants are then followed up for a specified period, and outcomes such as symptom improvement or adverse
effects are measured and compared between the two groups.
3. Limitations of RCTs:
While RCTs are considered the gold standard for assessing causal relationships and treatment efficacy, they do have
some limitations:
a. Ethical Considerations: In some cases, it may be ethically challenging or not feasible to include a control
group that does not receive any treatment or standard care.
Unlocking The Research Journey
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Unlocking The Research Journey
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Unlocking The Research Journey

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  • 2. 2 ِ‫ْم‬‫ي‬ ِ‫ح‬َّ‫الر‬ ِ‫ن‬ ٰ‫م‬ْ‫ح‬َّ‫الر‬ ِ‫هللا‬ ِ‫ْم‬‫س‬ِ‫ب‬ Unlocking The Research Journey By Dr. Syed M Haroon PREFACE .....................................................................................................................................................8 ACKNOWLEDGEMENT ............................................................................................................................9 INTRODUCTION ......................................................................................................................................10 What will we learn in this Booklet?............................................................................................................11 TITLE: THE EMERGENCE OF RESEARCH AND ITS REWARDS......................................................14 Introduction:................................................................................................................................................14 Section 1: Justified True Belief as the Foundation of Knowledge..........................................................14 Section 2: Research as the Means to Expand Knowledge ......................................................................14 2.1 Research as an Extension of Knowledge:.....................................................................................14 2.2 The Role of Experience, Study, and Investigation:.......................................................................14 2.3 The Justification of Belief through Research:...............................................................................14 Section 3: The Rewards of Research ......................................................................................................14 3.1 Intellectual Fulfillment:.................................................................................................................14 3.2 The “AAHH” Moment:.................................................................................................................15 Conclusion: .............................................................................................................................................15 TITLE: UNDERSTANDING RESEARCH: A SYSTEMATIC PURSUIT OF KNOWLEDGE ...............16 Introduction:................................................................................................................................................16 Section 1: Defining Research..................................................................................................................16 Section 2: Types of Research ..................................................................................................................16 2.1 Quantitative Research:..................................................................................................................16 2.2 Qualitative Research:....................................................................................................................16 2.3 Mixed Methods Research: ............................................................................................................17 Section 3: Applications and Comparisons ..............................................................................................17
  • 3. 3 3.1 Clinical Research and Quantitative Emphasis: .............................................................................17 3.2 Endogeneity in Qualitative Research:...........................................................................................17 3.3 Comparative Analysis in Quantitative Research:..........................................................................17 Conclusion: .............................................................................................................................................17 TITLE: SELECTING AN AREA OF INTEREST FOR RESEARCH: CONSIDERATIONS AND CRITERIA..................................................................................................................................................18 Introduction:................................................................................................................................................18 Section 1: Broadness and Multiple Outcomes ........................................................................................18 The Significance of a Broad Area of Interest:.....................................................................................18 Section 2: Criteria for Choosing an Area of Interest...............................................................................18 2.1 Relevance:.....................................................................................................................................18 2.2 Novelty:.........................................................................................................................................18 2.3 Acceptability: ................................................................................................................................18 2.4 Cost-effectiveness:........................................................................................................................19 2.5 Ethical Issues: ...............................................................................................................................19 Section 3: Proposal Evaluation Process..................................................................................................19 3.1 Committee-Based Evaluation: ......................................................................................................19 Conclusion: .............................................................................................................................................19 TITLE: RESEARCH OBJECTIVES: SETTING SPECIFIC AND MEASURABLE INTENTIONS .......20 Introduction:................................................................................................................................................20 Subjective Elements:...............................................................................................................................20 Objective Elements:................................................................................................................................20 Section 1: The Significance of Specific Research Objectives ................................................................20 1.1 Defining Research Objectives:......................................................................................................20 1.2 Clarity through Specificity:...........................................................................................................20 Section 2: The Role of Objective Elements in Research Objectives ......................................................21 2.1 The Importance of Objective Elements or Phrases:......................................................................21 2.2 Action Words for Measurability:...................................................................................................21 2.3 Measurability, Reproducibility, and Comparability:.....................................................................21 Conclusion: .............................................................................................................................................21 TITLE: OPERATIONAL DEFINITION: ENHANCING CLARITY AND PRECISION IN RESEARCH ....................................................................................................................................................................22 Introduction:................................................................................................................................................22 Section 1: Defining Operational Definition............................................................................................22
  • 4. 4 1.1 Clarifying Terms and Variables:....................................................................................................22 1.2 Enhancing Clarity and Precision:..................................................................................................22 Section 2: Operational Definition as a Variable of Study .......................................................................22 2.1 The Nature of Data Collection:.....................................................................................................22 2.2 Defining Data Variables:...............................................................................................................23 Section 3: Eliminating Ambiguity through Operational Definition........................................................23 3.1 Ambiguity in Research:.................................................................................................................23 3.2 The Role of Operational Definition: .............................................................................................23 Conclusion: .............................................................................................................................................23 TITLE: LITERATURE REVIEW: A COMPREHENSIVE EXAMINATION OF KEY SOURCES.........24 Introduction:................................................................................................................................................24 Section 1: Keyword Utilization in Literature Review.............................................................................24 1.1 Importance of Keywords:..............................................................................................................24 1.2 Keyword Usage:............................................................................................................................24 Section 2: Recommended Sources for Literature Review ......................................................................24 ➢ Pub Med:.....................................................................................................................................24 ➢ National Institute of Health National Library of Medicine:........................................................24 ➢ Academic Databases:..................................................................................................................25 ➢ Academic Journals:.....................................................................................................................25 ➢ Books and E-books: ....................................................................................................................25 ➢ Government and Institutional Reports:.......................................................................................25 ➢ Professional Associations and Organizations:.............................................................................25 ➢ Theses and Dissertations:............................................................................................................25 ➢ Conference Proceedings:.............................................................................................................26 Section 3: Time Investment for Literature Review.................................................................................26 3.1 Duration of Literature Review:.....................................................................................................26 Section 4: Potential for Refinement Based on Literature Review Findings ...........................................26 4.1 Adaptability of Area of Interest, Objectives, and Operational Definitions:..................................26 4.2 Critical Decision-Making Point: ...................................................................................................26 Conclusion: .............................................................................................................................................26 TITLE: CONDUCTING RESEARCH: A COMPREHENSIVE GUIDE...................................................27 Introduction:................................................................................................................................................27 Section 1: Identifying Variables in the Study..........................................................................................27
  • 5. 5 1.1 Variable Identification:..................................................................................................................27 Section 2: Selecting the Study Population ..............................................................................................27 2.1 Defining the Study Population:.....................................................................................................27 Section 3: Understanding Confounding Variables ..................................................................................28 3.1 Confounding Variables:.................................................................................................................28 3.2 Limitations and Unavoidable Confounding Factors: ....................................................................28 Section 4: Incorporating Confounding Factors into Objective Formulation...........................................29 4.1 Consideration of Confounding Factors:........................................................................................29 Conclusion: .............................................................................................................................................29 TITLE: STUDY DESIGN: A COMPREHENSIVE OVERVIEW..............................................................30 Introduction:................................................................................................................................................30 Section 1: Descriptive Study Designs.....................................................................................................30 1.1 Case Report:..................................................................................................................................30 1.2 Case Series:...................................................................................................................................30 1.3 Cross-sectional Study: ..................................................................................................................30 Section 2: Advantages and Considerations .............................................................................................30 2.1 Advantages:...................................................................................................................................30 2.2 Considerations: .............................................................................................................................31 Conclusion: .............................................................................................................................................31 TITLE: ANALYTICS: OBSERVATIONAL AND EXPERIMENTAL STUDY APPROACHES..............32 Introduction.............................................................................................................................................32 Section 1: Observational Studies ............................................................................................................32 1.1 Cohort Study:................................................................................................................................32 1.2 Case-Control Study:......................................................................................................................32 Section 2: Experimental Studies .............................................................................................................32 2.1 Intervention:......................................................................................................................................32 2.2 Comparison:......................................................................................................................................32 Conclusion: .............................................................................................................................................33 TITLE: SAMPLING METHODS: ENSURING REPRESENTATIVE DATA COLLECTION.................34 Introduction.............................................................................................................................................34 Section 1: Non-Probability Sampling Methods ......................................................................................34 1.1 Consecutive Sampling: .................................................................................................................34 1.2 Purposive Sampling: .....................................................................................................................34
  • 6. 6 1.3 Convenience Sampling: ................................................................................................................34 Section 2: Probability Sampling Methods ..............................................................................................34 2.1 Simple Random Sampling: ...........................................................................................................34 2.2 Systematic Sampling:....................................................................................................................34 2.3 Stratified Sampling: ......................................................................................................................35 2.4 Cluster Sampling:..........................................................................................................................35 Conclusion: .............................................................................................................................................35 TITLE: DATA COLLECTION METHODS: QUESTIONNAIRES, SURVEYS, AND FOCUS GROUP DISCUSSIONS/INTERVIEWS..................................................................................................................36 Introduction:................................................................................................................................................36 Section 1: Questionnaires .......................................................................................................................36 1.1 Definition and Purpose: ................................................................................................................36 1.2 Limitations:...................................................................................................................................36 Section 2: Surveys...................................................................................................................................36 2.1 Definition and Purpose: ................................................................................................................36 2.2 Implementation and Benefits: .......................................................................................................36 Section 3: Focus Group Discussions/Interviews.....................................................................................36 3.1 Definition and Purpose: ................................................................................................................36 3.2 Implementation and Benefits: .......................................................................................................37 TITLE: DATA PREPARATION AND SUMMARIZATION IN RESEARCH...........................................38 Introduction:................................................................................................................................................38 Section 1: Data Preparation.....................................................................................................................38 1.1 Representation of Data:.................................................................................................................38 Section 2: Data Summarization Measures ..............................................................................................38 1) Mean: ..............................................................................................................................................38 2) Median: ...........................................................................................................................................38 3) Mode:..............................................................................................................................................39 4) Range: .............................................................................................................................................39 5) Variance: .........................................................................................................................................39 6) Standard Deviation:.........................................................................................................................39 Section 3: Null Hypothesis and p-value..................................................................................................40 3.1 Null Hypothesis: ...........................................................................................................................40 3.2 P-value and Hypothesis Testing:...................................................................................................40
  • 7. 7 Conclusion: .............................................................................................................................................40 Conceptual Breakdown ............................................................................................................................41 The epistemological framework..................................................................................................................41 Quantitative Research:................................................................................................................................42 Qualitative Research:..................................................................................................................................42 Mixed Methods Research:...........................................................................................................................42 Objective:....................................................................................................................................................43 Data Variables .............................................................................................................................................44 Types of study designs: ...............................................................................................................................45 Here you can calculate sample size easily...................................................................................................48 Cluster And Strata .......................................................................................................................................49 Standard deviation......................................................................................................................................50 Null Hypothesis ...........................................................................................................................................51 P-Value And Hypothesis Testing..................................................................................................................52 PROPOSAL WRITING ...........................................................................................................................54 QUESTIONNAIRE...................................................................................................................................64 RELIABILITY OF QUESTIONNAIRE.................................................................................................70 GANTT CHART.......................................................................................................................................72
  • 8. 8 PREFACE Assalam-O-Alaikum, I am pleased to introduce a comprehensive research guide designed to empower undergraduate students in conducting successful research. In today's research-focused world, we understand that students often face challenges when it comes to selecting topics, research methodology, REC (Research Ethics Committee) approval, and publication acceptance. This guide aims to simplify the process and provide clarity on these crucial aspects. The purpose of this guide is to demystify research and equip you with the necessary tools to overcome common hurdles. By focusing on the fundamentals, we aim to provide a solid foundation for your academic journey, helping you avoid bias or rejection during the publication process. Throughout this booklet, we delve into critical steps and considerations essential for research success. I attended a research workshop, which, combined with internet resources, contributed to the creation of this guide. We value your feedback and questions, as they help us to improve and cater to your needs. Our commitment is to support you on your research path, so please don't hesitate to reach out with any inquiries or concerns. Thank you for your interest and support. We look forward to being part of your research journey. Regards, Syed M. Haroon syedharoon193@gmail.com
  • 9. 9 ACKNOWLEDGEMENT I am delighted to express my sincere gratitude and acknowledgment to Study Aid Project, Islamic Jamiat-e-Talaba for their invaluable support in my self-development and fostering an Islamic worldview and paradigm. Their dedication to providing educational resources and opportunities has played a vital role in shaping my personal growth and understanding. I am deeply grateful to my family for their unwavering support and encouragement in every aspect of my life. Their love, guidance, and unwavering belief in my abilities have been the driving force behind my accomplishments. Furthermore, I would like to extend my heartfelt appreciation to Prof. Muhammad Ilyas Siddiqui, Chairman, Department of Community Medicine at LUMHS, for reviewing and providing valuable feedback on my work. His expertise and insights have greatly enhanced the quality of my research. Sincerely, Syed M. Haroon Nazim e LUMHS
  • 10. 10 INTRODUCTION Throughout this booklet, we delve into the critical steps and considerations that are crucial for your research success. By following the guidelines presented, you will be able to: 1. Choose an engaging and relevant research topic: We provide strategies and tips to assist you in selecting a research area that aligns with your interests and academic goals. 2. Determine the most suitable research methodology: We explore various research methodologies, ensuring that you can confidently select an approach that aligns with your research objectives. 3. Minimize bias in your research: We emphasize the significance of impartiality and offer practical techniques to mitigate bias at every stage of your study, from design to analysis. 4. Navigate the REC approval process: We guide you through the REC application process, providing insights to help streamline your submission and increase your chances of approval. 5. Enhance publication acceptance: We address common factors that can contribute to rejection and provide valuable recommendations to maximize the likelihood of your research being accepted for publication.
  • 11. 11 What will we learn in this Booklet? A Systematic Overview of Research Fundamentals 1. Introduction - Provide an overview of the importance of research and its role in advancing knowledge. - Highlight the need for a systematic approach to conducting research. 2. Area of Interest - Explain the significance of selecting a broad and relevant area of interest. -Discuss the criteria for choosing an area of interest, including relevance, novelty, acceptability, cost-effectiveness, and ethical considerations. -Mention the importance of considering the potential for multiple outcomes and the opportunity to contribute to multiple papers/articles. 3. Research Objectives - Define the characteristics of specific and measurable research objectives. - Emphasize the use of action words to clearly state the intended outcomes of the research. - Discuss the importance of aligning research objectives with the chosen area of interest. 4. Literature Review -Explain the role of the literature review in research. -Discuss the use of keywords and recommended sources such as Pub Med and the National Library of Medicine. -Highlight the time required for conducting a thorough literature review. -Mention the potential for refining the area of interest, objectives, and operational definitions based on the findings of the literature review.
  • 12. 12 5. Study Design -Introduce different study designs, including descriptive and analytical designs. -Discuss the characteristics and uses of descriptive designs such as case reports, case series and cross-sectional studies. -Explain the distinction between observational studies (cohort and case-control) and experimental studies (intervention-based). 6. Sampling Size & Methods - Categorize sampling methods into non-probability and probability techniques. - Discuss non-probability methods such as consecutive and purposive sampling. - Explain probability methods including simple random, systematic, stratified, and cluster sampling. 7. Data Collection - Introduce various data collection methods. - Discuss the use of questionnaires, surveys, and focus group discussions/interviews. - Highlight the applicability of these methods to both quantitative and qualitative research. 8. Data Preparation and Summarization - Explain the process of data preparation. - Discuss the representation of data through frequency tables, charts, and graphs. - Introduce key summarization measures, including mean, median, mode, range, variance, and standard deviation. 9. Null Hypothesis and p-value - Define the null hypothesis and its role in research. - Discuss the use of the p-value as a parameter in hypothesis testing. - Mention the commonly used significance level of 0.05 for decision-making.
  • 13. 13 10. Conclusion - Summarize the key components of research fundamentals. - Highlight the importance of systematically approaching research to ensure rigorous and Ethical studies. - Stress the value of research in contributing to the advancement of knowledge and addressing important societal issues. 11. Proposal Writing Welcome to the world of proposal writing! In this concise booklet, you'll gain the essential knowledge and step-by-step guidance to successful proposal writing. Discover the purpose, components, and significance of proposals while learning practical tips and best practices. 12. Questionnaire Welcome to questionnaire design! This guide provides concise, step-by-step instructions to create effective surveys. Learn best practices, avoid common mistakes, and gain the skills to design engaging questionnaires. From research objectives to question types,generating valuable data for informed decision-making. Let's unlock the potential of your research through impactful questionnaire design!" 13. Gantt Chart "What is a Gantt Chart? Its Importance, Significance, and How to Develop One." Additionally, we are excited to announce that soon we will be publishing another booklet specifically focused on manuscript writing and publication. In this upcoming publication, we will discuss in-depth topics such as writing an impactful abstract, structuring your manuscript effectively, selecting the right research journal, and navigating the publication process. This resource will provide valuable insights and practical advice to help you effectively communicate your research findings to the academic community and increase your chances of publication success. We hope that this booklet, along with the forthcoming publication on manuscript writing and publication, will serve as indispensable resources on your research journey, enabling you to conduct high-quality research and effectively disseminate your findings to the broader scientific community.
  • 14. 14 TITLE: THE EMERGENCE OF RESEARCH AND ITS REWARDS Introduction: Research is the product of human cognition, driven by the exploration of possibilities beyond the boundaries of certainties. It is a fundamental process that leads us from the realm of “yes” or “no” to the nuanced realm of “maybe.” This transformation in thinking allows us to challenge preconceived notions and delve into the complexities of knowledge. This booklet examines the relationship between research and knowledge, emphasizing the concept of justified true belief and the rewards that research offers. Section 1: Justified True Belief as the Foundation of Knowledge Knowledge Traditionally defined as justified true belief, forms the basis of our understanding. This framework acknowledges that knowledge must be well-founded and supported by valid justifications to attain the status of truth. The epistemological framework is sued to acquire valid knowledge. Section 2: Research as the Means to Expand Knowledge 2.1 Research as an Extension of Knowledge: Research serves as a vehicle for the expansion of knowledge beyond existing boundaries. It acts as a catalyst for the progression from established truths to more refined and comprehensive understandings. 2.2 The Role of Experience, Study, and Investigation: Through the amalgamation of personal experience, dedicated study, and rigorous investigation, researchers gain valuable insights that contribute to the advancement of knowledge. By exploring uncharted territories, researchers can confirm or refute existing beliefs, gradually building a more accurate and nuanced understanding of various phenomena. 2.3 The Justification of Belief through Research: Research plays a crucial role in the justification of beliefs. By subjecting hypotheses and assumptions to systematic investigation and analysis, researchers can validate or reject them based on empirical evidence and logical reasoning. This process ensures that beliefs are grounded in sound and reliable foundations. Section 3: The Rewards of Research 3.1 Intellectual Fulfillment: Research offers a profound sense of satisfaction and intellectual fulfillment. The pursuit of knowledge and the discovery of new insights provide researchers with a deep sense of accomplishment, expanding their intellectual horizons and fostering personal growth.
  • 15. 15 3.2 The “AAHH” Moment: A notable reward of research is the euphoric “AAHH” moment. It represents the exhilaration experienced when a researcher successfully unveils a significant finding or solves a long- standing problem. This moment of revelation not only confirms the value of research but also motivates further exploration and innovation. Conclusion: Research emerges from the transition from binary thinking to a realm of possibilities, and it plays a pivotal role in the growth and refinement of knowledge. By upholding the principles of justified true belief, researchers strive to uncover the truth through experience, study, and investigation. The rewards of research, including intellectual fulfillment and the exhilarating “AAHH” moment, fuel the continuous pursuit of knowledge and contribute to the advancement of society as a whole.
  • 16. 16 TITLE: UNDERSTANDING RESEARCH: A SYSTEMATIC PURSUIT OF KNOWLEDGE Introduction: Research is a formal and systematic endeavor aimed at expanding the existing body of knowledge and devising new applications. It encompasses a process of data collection, analysis, and interpretation with the ultimate goal of finding solutions to problems. The results of research are made available to the wider community, fostering the growth and dissemination of knowledge. This booklet explores the different types of research, namely quantitative, qualitative, and mixed methods, highlighting their characteristics and applications in various fields, with a particular focus on clinical research. Section 1: Defining Research The Quest for Knowledge: Research is a formal and systematic undertaking driven by the pursuit of knowledge. It involves rigorous investigation, analysis, and exploration of various subjects or phenomena to uncover new insights and deepen our understanding. Expanding the Stock of Knowledge: A key objective of research is to contribute to the expansion of the existing stock of knowledge. By generating the latest information, theories, and concepts, research enriches our collective understanding and opens doors to the development of innovative applications in various domains. Section 2: Types of Research 2.1 Quantitative Research: Quantitative research relies on numerical data and statistical analysis to investigate and explore relationships, patterns, and trends. It often involves large-scale studies, surveys, or experiments, providing a structured and measurable approach to gather information. Quantitative research plays a significant role in clinical studies, offering insights into treatment effectiveness, patient outcomes, and disease prevalence. Example: Study examining the relationship between sleep duration and academic performance among college students. 2.2 Qualitative Research: Qualitative research focuses on exploring and understanding the subjective experiences, beliefs, attitudes, and behaviors of individuals or groups. It employs methods such as interviews, observations, and analysis of textual or visual data to generate rich and context-dependent
  • 17. 17 insights. Qualitative research is often conducted within specific communities or populations, allowing for an in-depth exploration of their unique perspectives and experiences. Example: Study exploring the experiences of immigrants transitioning to a new country. 2.3 Mixed Methods Research: Mixed methods research integrates both quantitative and qualitative approaches within a single study. This methodological approach enables researchers to use the strengths of both methodologies, combining statistical analysis with contextual understanding. By employing mixed methods, researchers can triangulate findings, provide comprehensive explanations, and gain a more holistic understanding of complex phenomena. Example: A study on the effectiveness of a teacher training program on student engagement in a primary school. Section 3: Applications and Comparisons 3.1 Clinical Research and Quantitative Emphasis: Clinical research, as a specialized domain, heavily relies on quantitative methods. The objective is to evaluate the efficacy of treatments, assess medical interventions, and quantify patient outcomes. The emphasis on numerical data and statistical analysis enables researchers to draw evidence-based conclusions and guide medical decision-making. 3.2 Endogeneity in Qualitative Research: Qualitative research acknowledges the importance of context and aims to capture the unique experiences of individuals or groups within a specific setting. This endogenous approach recognizes the inherent subjectivity and seeks to explore the perspectives of the participants to gain a deeper understanding of their lived realities. 3.3 Comparative Analysis in Quantitative Research: Quantitative research allows for the comparison of studies conducted by separate groups on the same topic. By employing standardized methodologies and statistical analyses, researchers can objectively assess and compare findings to identify consistencies or inconsistencies. This comparative approach enhances the validity and reliability of research outcomes. Conclusion: Research is a systematic and formal process that expands the stock of knowledge, generates innovative applications, and provides solutions to problems. The distinction between quantitative, qualitative, and mixed methods research enables researchers to approach investigations from different perspectives and address complex phenomena comprehensively. By embracing the diverse methodologies available, researchers can contribute to a multidimensional understanding of the world and promote advancements in various fields of study.
  • 18. 18 TITLE: SELECTING AN AREA OF INTEREST FOR RESEARCH: CONSIDERATIONS AND CRITERIA Introduction: Choosing a suitable area of interest for research is a critical step that sets the foundation for successful academic exploration. The selected area should have broad relevance, offer multiple outcomes for extensive research output, and meet certain criteria to ensure its acceptability. This booklet explores the criteria for selecting an area of interest, emphasizing factors such as relevance, novelty, acceptability, cost-effectiveness, and ethical considerations. Additionally, it proposes a committee-based evaluation process that determines the acceptance of research proposals based on a score threshold. Section 1: Broadness and Multiple Outcomes The Significance of a Broad Area of Interest: Selecting a broad area of interest: Such as diabetes or myocardial infarction, provides ample opportunities for in-depth exploration and multiple research outcomes. This approach allows researchers to delve into various aspects, subtopics, or associated factors within the chosen area, thereby enabling the production of multiple papers or articles. Section 2: Criteria for Choosing an Area of Interest 2.1 Relevance: Relevance is a crucial criterion for selecting an area of interest. Researchers should consider the practical importance and applicability of their chosen area, such as investigating the prevalence and impact of dengue in Pakistan. The chosen topic should address a current issue or problem that has implications for society, healthcare, or a specific field of study. 2.2 Novelty: Identifying a research gap is essential in selecting an area of interest. Researchers should explore existing literature to determine if there is a dearth of studies or unexplored aspects within their chosen field. By focusing on uncharted territories or unresolved questions, researchers can contribute new insights and knowledge to the existing body of literature. 2.3 Acceptability: The chosen area of interest should be phrased in a positive manner to ensure acceptability. Avoiding negative connotations, such as phrases like “incompatibility of teachers in our university,” ensures a more constructive and unbiased approach. Framing the research question
  • 19. 19 or topic in a positive light facilitates a more favorable reception by the academic community and enhances the potential for collaboration and support. 2.4 Cost-effectiveness: Researchers should consider the cost implications associated with their chosen area of interest. It is important to evaluate the feasibility of conducting research within the available resources, including funding, equipment, and personnel. Selecting an area that aligns with available resources ensures that the research can be conducted efficiently and effectively. 2.5 Ethical Issues: Ethical considerations play a crucial role in selecting an area of interest. Researchers must assess whether their proposed research complies with ethical guidelines and safeguards the rights and well-being of participants. Evaluating potential ethical concerns and ensuring appropriate measures for informed consent, confidentiality, and data protection are in place are essential aspects of responsible research. Section 3: Proposal Evaluation Process 3.1 Committee-Based Evaluation: A committee-based evaluation process can be employed to assess the acceptance of research proposals. The committee evaluates the proposals based on predetermined criteria and assigns scores to each criterion. The total score required for proposal acceptance should be set at a threshold, such as 70% of the total score, to ensure that proposals meet the necessary standards for research approval. Conclusion: Selecting an area of interest for research requires careful consideration and adherence to specific criteria. A broad area of interest offers opportunities for extensive exploration and multiple research outcomes. Relevance, novelty, acceptability, cost-effectiveness, and ethical considerations serve as crucial criteria when choosing an area of interest. By employing a committee-based evaluation process, research proposals can be rigorously assessed, ensuring that only high-quality and impactful studies are approved for further investigation.
  • 20. 20 TITLE: RESEARCH OBJECTIVES: SETTING SPECIFIC AND MEASURABLE INTENTIONS Introduction: Research objectives play a crucial role in providing clear direction and focus to a research study. By establishing specific objectives, researchers can articulate their intentions in a measurable and actionable manner. Objective start with “TO” (to find out, to calculate, to compare) Subjective Elements: Subjective elements in research objectives are influenced by individual perceptions, interpretations, or knowledge. These elements may vary among researchers or participants and can introduce bias or subjective interpretations. For example, referring to an abdominal swelling as "huge" represents a subjective element that may differ depending on the observer's perspective. Objective Elements: Objective elements within research objectives are universally applicable and can be observed or measured consistently. These elements provide a common ground for researchers to assess and compare findings. For example, stating an objective to determine the size of a swelling on the right hypochondrium as 10 by 10 represents an objective element that is measurable and reproducible. Section 1: The Significance of Specific Research Objectives 1.1 Defining Research Objectives: Research objectives outline the specific aims and goals of a study. These objectives guide the research process and help researchers stay focused on achieving measurable outcomes. 1.2 Clarity through Specificity: Specific research objectives provide clarity by clearly defining the scope and purpose of the study. They enable researchers to articulate their intentions in a precise and concise manner, facilitating effective planning and execution of the research. For example: The objective of this research study is to investigate the prevalence and risk factors associated with a (specific medical) diabetic mellitus condition among smoker (a selected population.)
  • 21. 21 Section 2: The Role of Objective Elements in Research Objectives 2.1 The Importance of Objective Elements or Phrases: Research objectives should employ objective Elements or phrases that are measurable, reproducible, and comparable. These terms enable researchers to establish clear parameters for data collection, analysis, and interpretation. 2.2 Action Words for Measurability: Research objectives should begin with action words that emphasize the measurable aspect of the study. Starting objectives with phrases like "to find out," "to calculate," or "to compare" sets the stage for specific and measurable outcomes. 2.3 Measurability, Reproducibility, and Comparability: Objective words in research objectives ensure that the intended outcomes can be measured, reproduced, and compared across different contexts. This allows for rigorous evaluation and the establishment of scientific validity. Conclusion: Research objectives form a vital component of any study, outlining specific intentions and guiding the research process. By utilizing objective Elements or phrases, researchers can ensure the clarity, measurability, reproducibility, and comparability of their objectives. The distinction between objective and subjective elements within research objectives emphasizes the importance of establishing measurable criteria that can be universally applied and evaluated. By setting clear and specific research objectives, researchers enhance the validity, reliability, and impact of their studies.
  • 22. 22 TITLE: OPERATIONAL DEFINITION: ENHANCING CLARITY AND PRECISION IN RESEARCH Introduction: Operational definition is a critical aspect of research that ensures clarity and precision in the use of words or terms. It serves the purpose of explaining or defining specific words or variables within the research objectives. Here we highlight the significance of operational definition in research, emphasizing its role in providing clear and unambiguous explanations. Furthermore, it underscores the understanding that data collection involves variables, and operational definitions are essential in establishing the parameters of these variables. For example: If we use the term 'diabetes mellitus' in our objective, we need to explain what diabetes mellitus is, and if there is any cutoff value, we must mention it. Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels (hyperglycemia) resulting from either insufficient insulin production by the pancreas or the body's inability to effectively utilize insulin. To diagnose an individual with diabetes, a fasting blood sugar level of 126 mg/dL (7.0 mmol/L) or higher on two separate occasions is typically considered the cutoff value. This criterion helps identify sustained hyperglycemia, indicating the presence of diabetes. Section 1: Defining Operational Definition 1.1 Clarifying Terms and Variables: Operational definition refers to the process of providing explicit explanations or definitions for words, terms, or variables used within a research study. It serves to minimize ambiguity and promote consistent interpretations among researchers. 1.2 Enhancing Clarity and Precision: The purpose of operational definition is to enhance clarity and precision in research. By precisely defining key concepts, terms, or variables, researchers establish a common understanding and facilitate accurate communication throughout the study. Section 2: Operational Definition as a Variable of Study 2.1 The Nature of Data Collection: Data collection is an integral part of research, involving the gathering of information or observations related to the study's objectives. Within this process, data itself can be considered a variable that requires operational definition.
  • 23. 23 2.2 Defining Data Variables: Operational definitions play a crucial role in establishing the parameters of data variables. Researchers must clearly define the nature, type, and characteristics of the data they collect. By doing so, they ensure consistency in the measurement and interpretation of data across the study. Section 3: Eliminating Ambiguity through Operational Definition 3.1 Ambiguity in Research: Ambiguity can arise when terms or variables are loosely defined or open to multiple interpretations. This can lead to confusion, inconsistency, and potential biases in the research process and outcomes. Ambiguous Objective: "To study the effects of a new drug on patient outcomes." Revised Objective: "To assess the efficacy and safety of Drug X in reducing symptom severity and improving quality of life in patients with moderate to severe asthma through a randomized controlled trial." In the revised objective, the ambiguity is addressed by specifying the drug under investigation (Drug X), the targeted patient population (those with moderate to severe asthma), and the specific outcomes of interest (reducing symptom severity and improving quality of life). This clarification provides a clear focus for the research study. 3.2 The Role of Operational Definition: Operational definition acts as a safeguard against ambiguity by providing explicit explanations or definitions. By precisely describing the meaning, scope, and measurement of key terms or variables, researchers eliminate potential confusion and ensure that their study is clear and unambiguous. Conclusion: Operational definition is an essential tool in research, enabling researchers to enhance clarity, precision, and consistency in their work. By explicitly defining terms, variables, and data parameters, researchers establish a common understanding and eliminate ambiguity. This promotes accurate communication, reliable interpretation, and valid conclusions. Emphasizing the importance of operational definition contributes to the overall quality and rigor of research, ultimately enhancing its impact and value.
  • 24. 24 TITLE: LITERATURE REVIEW: A COMPREHENSIVE EXAMINATION OF KEY SOURCES Introduction: The literature review is a critical component of the research process, providing a comprehensive examination of existing knowledge and research on a specific topic. Here we highlight the importance of utilizing relevant keywords during the literature review, along with recommended sources such as Pub Med and the National Library of Medicine. Furthermore, it acknowledges that the literature review phase often requires a significant time investment, typically around two weeks, and emphasizes the potential for refining the area of interest, objectives, and operational definitions based on the review's findings. Section 1: Keyword Utilization in Literature Review 1.1 Importance of Keywords: Keywords serve as essential tools in the literature review process, enabling researchers to locate relevant studies and articles. They facilitate effective searching, both by others seeking to find the researcher's study and by the researcher when studying other research. 1.2 Keyword Usage: During the literature review, researchers should carefully consider the keywords used by others to locate their study and incorporate those keywords into their own searches. This approach ensures comprehensive coverage of relevant literature and allows for a more comprehensive understanding of the topic. Section 2: Recommended Sources for Literature Review ➢ Pub Med: Pub Med, a widely recognized and authoritative database, offers an extensive collection of biomedical literature. Researchers can access a wealth of scholarly articles, journals, and research studies related to their area of interest. Pub Med serves as a valuable resource for conducting comprehensive literature reviews. ➢ National Institute of Health National Library of Medicine: The National Institute of Health's National Library of Medicine provides access to an extensive array of biomedical literature and research resources. Its databases, such as PubMed Central, MEDLINE, and other specialized collections, offer researchers a wealth of information for their literature reviews.
  • 25. 25 ➢ Academic Databases: Academic Databases Access scholarly databases such as Pub Med, Google Scholar, Scopus, and Web of Science. These platforms provide access to a wide range of peer- reviewed journal articles, conference papers, theses, and dissertations. ➢ Academic Journals: Academic Journals Explore relevant journals in your field of study. Look for reputable journals that publish high-quality research articles and review papers. Examples include New England Journal of Medicine, The Lancet, Journal of the American Medical Association (JAMA), and British Medical Journal (BMJ). ➢ Books and E-books: Books and E-books Consult textbooks, monographs, and reference books written by experts in the field. Books often provide in-depth coverage of specific topics and can provide a historical context or theoretical framework for your research. ➢ Government and Institutional Reports: Government and Institutional Reports Check government reports, policy documents, and publications from reputable institutions such as the World Health Organization (WHO), Centers for Disease Control and Prevention (CDC), National Institutes of Health (NIH), United Nation (UN), United Nation International Children’s Emergency Fund (UNICEF) and other relevant governmental or non-governmental organizations. ➢ Professional Associations and Organizations: Professional Associations and Organizations Visit the websites of professional associations and organizations related to your research topic. These organizations often publish journals, reports, and guidelines that can provide valuable insights and current research in the field. ➢ Theses and Dissertations: Theses and Dissertations Explore relevant theses and dissertations in your field, which are often available through university libraries or digital repositories. These works can provide comprehensive reviews of the literature and may highlight gaps in research that can guide your own study.
  • 26. 26 ➢ Conference Proceedings: Conference Proceedings Check conference proceedings in your field, as they often contain cutting-edge research and preliminary findings. Some conferences also publish full papers or abstracts that can be valuable for your literature review. Section 3: Time Investment for Literature Review 3.1 Duration of Literature Review: The literature review phase of research typically requires a significant time investment. Researchers should allocate a minimum of 15 days, or approximately two weeks, to thoroughly review and analyze the relevant literature. This timeframe allows for a comprehensive examination of the existing knowledge base and facilitates the identification of research gaps and potential revisions to the research plan. Section 4: Potential for Refinement Based on Literature Review Findings 4.1 Adaptability of Area of Interest, Objectives, and Operational Definitions: The literature review phase offers researchers the opportunity to gain valuable insights from existing studies, potentially leading to adjustments in their area of interest, research objectives, and operational definitions. New information and perspectives obtained through the review process may prompt researchers to refine and realign their research plan for enhanced relevance and impact. 4.2 Critical Decision-Making Point: Once the literature review is completed and revisions are made to the area of interest, objectives, and operational definitions, researchers reach a critical decision-making point. At this stage, further adjustments may be difficult or impractical. Therefore, thorough consideration and consultation with advisors or peers are essential to ensure a well-informed and justified research direction. Conclusion: The literature review is a crucial phase in the research process, involving the utilization of relevant keywords and trusted sources such as PubMed and the National Library of Medicine. Allocating adequate time for the literature review phase, typically around two weeks, allows for a comprehensive examination of existing knowledge. Researchers should remain open to the potential refinement of their area of interest, objectives, and operational definitions based on the findings of the literature review. Careful attention to this process strengthens the research foundation, enhances the quality of the study, and contributes to the advancement of knowledge in the field.
  • 27. 27 TITLE: CONDUCTING RESEARCH: A COMPREHENSIVE GUIDE Introduction: Conducting research involves a systematic approach to investigating a specific topic, identifying variables, selecting the study population, and defining research objectives. This booklet provides a formal and beautified guide on how to conduct research effectively. It emphasizes the importance of understanding dependent and independent variables, the selection of the study population, and the consideration of confounding variables when formulating research objectives. Additionally, the influence of confounding variables on study design and the limitations they may impose are discussed. Section 1: Identifying Variables in the Study 1.1 Variable Identification: Variables form the foundation of research and can be categorized as dependent or independent. In the example of studying the relationship between pregnancy and anemia, pregnancy is the independent variable, while anemia is the dependent variable. Anemia is influenced by pregnancy, making it dependent, whereas pregnancy itself is not affected by anemia, making it independent. Section 2: Selecting the Study Population 2.1 Defining the Study Population: The selection of an appropriate study population is crucial for obtaining meaningful results. Researchers should clearly define the characteristics and criteria for selecting the study population to ensure it represents the target population accurately. Inclusion and exclusion criteria: Inclusion criteria: Clearly state and justify the specific characteristics that qualify individuals for participation in the study. Avoid overly restrictive criteria to ensure the generalizability of findings. For example: 1. Age: Participants aged 40-65 years. 2. Diabetes Diagnosis: Participants diagnosed with type 2 diabetes. 3. Smoking Status: Current smokers or individuals who have quit smoking within the past five years. 4. Health Condition: Participants with stable medical conditions and able to provide informed consent. Exclusion criteria: Clearly state and justify the specific characteristics that disqualify individuals from participating in the study. Be cautious of potential biases and carefully consider the balance between participant safety and sample representativeness.
  • 28. 28 For example: 1. Age: Participants below 40 years or above 65 years. 2. Diabetes Type: Participants with type 1 diabetes or other forms of diabetes. 3. Smoking Status: Non-smokers and individuals who quit smoking more than five years ago. 4. Unstable Health Condition: Participants with uncontrolled or severe co-morbidities that may confound the study outcomes. 5. Pregnancy: Pregnant or breastfeeding individuals due to potential effects on the study parameters. Transparency: Clearly communicate the criteria to ensure transparency and reproducibility of the study. Consistency: Apply the criteria consistently to all participants throughout the study. Ethical considerations: Address ethical implications, such as protecting vulnerable populations and managing conflicts of interest. Justification: Provide a clear rationale for each criterion to demonstrate its relevance and importance to the study. Section 3: Understanding Confounding Variables 3.1 Confounding Variables: Confounding variables are factors that can affect the study but are not the variables under investigation. They introduce a relationship between the dependent and independent variables, potentially distorting or influencing the observed cause-and-effect relationship. Inclusion and exclusion criteria should be carefully considered to address confounding variables effectively. Confounding Variable: Body Mass Index (BMI) Confounding Variable: BMI is a confounding variable that can potentially affect the relationship between diabetes, smoking, and the study outcomes. Higher BMI is associated with an increased risk of both diabetes and certain smoking-related health issues. If the distribution of BMI differs significantly between the included and excluded participants, it can introduce bias and confound the study results. To mitigate this, researchers may consider stratifying participants based on BMI or including it as a covariate in the analysis to account for its potential influence. 3.2 Limitations and Unavoidable Confounding Factors: While researchers strive to eliminate confounding variables, some factors may be inherently difficult or impossible to control. These limitations can impact the study's validity and may limit the extent to which the research findings can be generalized.
  • 29. 29 Non-Avoidable Confounding Factor: Socioeconomic Status (SES) Non-Avoidable Confounding Factor: Socioeconomic status (SES) is a non-avoidable confounding factor that may influence both diabetes and smoking behaviors. Individuals with lower SES may have a higher prevalence of diabetes and a higher likelihood of being smokers due to various factors such as limited access to healthcare, educational disparities, and stress. Although it is challenging to completely eliminate the influence of SES, researchers can attempt to minimize its impact by collecting and analyzing data on SES indicators, such as education level or income, and adjusting for them in statistical analyses. Non-avoidable confounding factors pose challenges in research studies as they cannot be directly controlled or eliminated. However, by carefully collecting and analyzing relevant data, researchers can account for these factors to the best of their ability and interpret study results in consideration of their potential influence. Section 4: Incorporating Confounding Factors into Objective Formulation 4.1 Consideration of Confounding Factors: When phrasing research objectives, it is crucial to keep confounding factors in mind. Objectives should be formulated in a manner that acknowledges and accounts for potential confounding variables, ensuring that the research design and data analysis adequately address these factors. Example: Myocardial Infarction (MI) in Patients with a Low-Fat Diet In the case of studying MI in patients who do not consume fat, potential confounding factors such as age, smoking habits, and pre-existing medical conditions should be considered. The objective formulation should explicitly address these confounding variables to ensure accurate and reliable research outcomes. Conclusion: Conducting research involves a systematic approach that encompasses variable identification, study population selection, and objective formulation. Understanding the distinction between dependent and independent variables, as well as the influence of confounding variables, is essential for designing robust research studies. By considering and accounting for confounding factors, researchers can enhance the validity and reliability of their findings, contributing to the advancement of knowledge in their respective fields.
  • 30. 30 TITLE: STUDY DESIGN: A COMPREHENSIVE OVERVIEW Introduction: Selecting an appropriate study design is crucial for conducting rigorous and informative research. This booklet provides overview of different study designs, specifically focusing on descriptive study designs. These designs include case reports, case series, and cross-sectional studies, each serving unique purposes in investigating specific research questions. Understanding these study designs aids researchers in choosing the most suitable approach for their research objectives. Section 1: Descriptive Study Designs 1.1 Case Report: A case report is a descriptive study design based on a single case that presents a unique or rare condition or outcome. It provides an in-depth analysis of an individual case, such as a case of lithopedion, shedding light on its clinical presentation, diagnostic process, and treatment. Case reports contribute valuable insights into understanding uncommon conditions or treatments and can serve as a foundation for further research. 1.2 Case Series: A case series is a descriptive study design that focuses on a collection of similar cases. It involves studying multiple cases of a particular condition, such as cases of lithopedion in different hospitals. Case series provide a broader perspective by analyzing similarities and variations across multiple cases, allowing for the identification of patterns, trends, or common characteristics. 1.3 Cross-sectional Study: A cross-sectional study is a descriptive study design that provides a snapshot of a specific population at a given time. It aims to determine the prevalence or presence of certain factors or conditions within a defined population. Cross-sectional studies are particularly useful for estimating the prevalence of a disease or assessing the distribution of risk factors. However, they do not establish causality or provide information on the incidence or temporal relationships between variables. Section 2: Advantages and Considerations 2.1 Advantages: Descriptive study designs offer several advantages. Case reports provide detailed information about rare or unique cases, contributing to medical knowledge and raising awareness. Case series offer insights into patterns and commonalities across multiple cases, aiding in the identification
  • 31. 31 of potential risk factors or treatment outcomes. Cross-sectional studies provide valuable prevalence data and facilitate the identification of potential associations. 2.2 Considerations: While descriptive study designs are valuable, they have limitations. Case reports and case series lack comparison groups, limiting their ability to establish causality or draw definitive conclusions. Cross-sectional studies provide a snapshot of data at a specific time, but they do not account for temporal relationships or establish cause-and-effect relationships. Conclusion: Descriptive study designs, including case reports, case series, and cross-sectional studies, play an essential role in research. They provide valuable insights into unique cases, patterns across multiple cases, and the prevalence of certain conditions or factors. Understanding the advantages and considerations of each design aids researchers in selecting the most appropriate approach to address their research questions and contributes to the advancement of knowledge in their respective fields.
  • 32. 32 TITLE: ANALYTICS: OBSERVATIONAL AND EXPERIMENTAL STUDY APPROACHES Introduction: Analytics plays a crucial role in research, providing valuable insights into relationships, outcomes, and interventions. Here we focus on two key components of analytics: observational studies and experimental studies. Observational studies encompass cohort studies and case- control studies, while experimental studies involve interventions and comparisons between different groups or conditions. Section 1: Observational Studies 1.1 Cohort Study: A cohort study involves a group of individuals with similar characteristics who are followed over time to examine the development of specific outcomes or conditions. It can be conducted in a prospective manner, where data is collected moving forward, or in a retrospective manner, where data is collected looking backward. Cohort studies provide valuable information on the natural history, risk factors, and outcomes of a particular condition. 1.2 Case-Control Study: A case-control study selects a population based on a specific disease or outcome and compares individuals who have developed the disease (cases) with those who have not (controls). By examining past exposures or characteristics, researchers can determine potential risk factors or associations with the development of the disease. Case-control studies are useful when studying rare conditions or outcomes. Section 2: Experimental Studies 2.1 Intervention: Experimental studies involve interventions or treatments that are administered to participants. Researchers compare the outcomes or responses between different groups or conditions to determine the effectiveness or impact of the intervention. Experimental studies provide a controlled environment to assess causality and establish the efficacy of interventions. 2.2 Comparison: In experimental studies, researchers typically compare two or more groups or conditions. These comparisons can involve different treatments, interventions, dosages, or control groups. By comparing the outcomes between groups, researchers can evaluate the relative effectiveness or differences in response.
  • 33. 33 Conclusion: Analytics in research includes both observational studies and experimental studies. Observational studies, such as cohort studies and case-control studies, provide insights into natural history, risk factors, and associations of specific conditions. Experimental studies involve interventions and comparisons between different groups or conditions to assess efficacy and causality. By employing a combination of observational and experimental approaches, researchers can gain a comprehensive understanding of relationships, outcomes, and interventions, advancing knowledge in their respective fields.
  • 34. 34 TITLE: SAMPLING METHODS: ENSURING REPRESENTATIVE DATA COLLECTION Introduction: Sampling is a critical aspect of research, as it involves selecting a subset of individuals from a larger population to gather data. In this booklet we discusses various sampling methods, and calculating sampling size that researchers can employ to ensure representative data collection. These methods can be categorized into non-probability sampling, where not everyone has an equal chance of participation, and probability sampling, where everyone has an equal chance of participation. Section 1: Non-Probability Sampling Methods 1.1 Consecutive Sampling: Consecutive sampling involves selecting participants in a continuous sequence, such as including the first 5 subjects from a total of 10. This method may introduce bias if the order of selection affects the sample's representativeness. 1.2 Purposive Sampling: Purposive sampling involves selecting participants based on specific criteria or characteristics that align with the research objectives. Researchers intentionally choose individuals who possess the desired qualities to provide in-depth insights into the research topic. 1.3 Convenience Sampling: Convenience sampling involves selecting participants based on their easy accessibility or availability to the researcher. This method is convenient but may introduce bias due to the non- random selection of participants. Section 2: Probability Sampling Methods 2.1 Simple Random Sampling: Simple random sampling involves randomly selecting individuals from the population, giving each person an equal chance of being included. This method is commonly used for small populations and can be conducted using techniques like balloting or random number generation. 2.2 Systematic Sampling: Systematic sampling involves selecting participants at fixed intervals from a larger population. The total population is divided by the desired sample size, and participants are selected based on
  • 35. 35 a pre-determined pattern, such as every nth person on a list. This method ensures a representative sample and is useful for large populations. 2.3 Stratified Sampling: Stratified sampling involves dividing the population into distinct subgroups or strata based on specific characteristics. Researchers then randomly select participants from each stratum in proportion to their representation in the overall population. This method ensures adequate representation of each subgroup and is useful when certain subgroups have unique characteristics or differences. 2.4 Cluster Sampling: Cluster sampling involves selecting groups or clusters of participants rather than individual participants. Clusters can be geographical regions, schools, or organizations. Researchers randomly select clusters and then collect data from all individuals within the selected clusters. This method is efficient when participants within clusters share similar characteristics. Conclusion: Choosing an appropriate sampling method is essential to ensure representative data collection in research. Non-probability sampling methods, such as consecutive, purposive, and convenience sampling, offer convenience but may introduce bias. Probability sampling methods, including simple random sampling, systematic sampling, stratified sampling, and cluster sampling, provide more reliable and representative results. Researchers should carefully consider the characteristics of their population and research objectives when selecting the most appropriate sampling method for their study.
  • 36. 36 TITLE: DATA COLLECTION METHODS: QUESTIONNAIRES, SURVEYS, AND FOCUS GROUP DISCUSSIONS/INTERVIEWS Introduction: Data collection is a crucial step in research, allowing researchers to gather information and insights from participants. There are three commonly used data collection methods: questionnaires, surveys, and focus group discussions/interviews. Each method has its unique characteristics and suitability for different types of studies, whether quantitative or qualitative. Section 1: Questionnaires 1.1 Definition and Purpose: Questionnaires involve presenting a set of structured questions to participants, typically in a written format. They are designed to collect quantitative data and gather information directly from the participants themselves. 1.2 Limitations: Questionnaires have some limitations. They heavily rely on self-reporting, which may introduce response bias or inaccuracies. Participants' interpretations of the questions and their willingness to disclose certain information can also impact the quality of the data collected. Section 2: Surveys 2.1 Definition and Purpose: Surveys involve direct interaction between the researcher and the participants. Researchers administer a series of pre-designed questions to gather quantitative data, often using various data collection tools such as interviews, telephone calls, or online platforms. 2.2 Implementation and Benefits: Surveys allow researchers to collect data in a controlled manner and clarify any questions participants may have. They provide a higher level of researcher control compared to questionnaires. Surveys are particularly useful for obtaining numerical data and identifying patterns or trends in large populations. Section 3: Focus Group Discussions/Interviews 3.1 Definition and Purpose: Focus group discussions/interviews involve bringing together a small group of individuals or conducting individual interviews to gather qualitative data. Researchers facilitate discussions or
  • 37. 37 conduct interviews to explore participants' perspectives, experiences, and opinions on a specific topic. 3.2 Implementation and Benefits: Focus group discussions/interviews provide rich and in-depth qualitative data. They offer a deeper understanding of participants' thoughts, emotions, and motivations. The interactive nature of these methods allows for probing and follow-up questions, promoting insightful discussions among participants. Conclusion: When planning data collection for a research study, researchers must carefully consider the nature of the study and the type of data required. Questionnaires and surveys are effective tools for collecting quantitative data from participants, while focus group discussions/interviews provide valuable qualitative insights. By selecting the appropriate data collection method, researchers can ensure they gather relevant and reliable data to support their research objectives and contribute to the advancement of knowledge in their field.
  • 38. 38 TITLE: DATA PREPARATION AND SUMMARIZATION IN RESEARCH Introduction: Data preparation and summarization play a crucial role in research, allowing researchers to analyze and present their data effectively. In this booklet we explores various techniques for preparing and summarizing data, including frequency tables, charts, graphs, and key statistical measures such as mean, median, mode, range, variance, and standard deviation. Additionally, it discusses the significance of the null hypothesis in research and the importance of considering the p-value when testing hypotheses. Section 1: Data Preparation 1.1 Representation of Data: Data can be represented using different formats, such as frequency tables, charts, and graphs, depending on the type of data and the purpose of analysis. These visual representations enhance understanding and facilitate data interpretation. Section 2: Data Summarization Measures 1) Mean: The mean, also known as the average, is calculated by summing up all the values in a dataset and dividing it by the total number of values. It represents the central tendency of the data. Example: Consider a dataset of ages of five individuals: 25, 30, 35, 40, and 45. To find the mean, add up all the values (25 + 30 + 35 + 40 + 45 = 175) and divide by the total number of values (5). The mean age in this case is 35 (175 divided by 5). 2) Median: The median represents the middle value in a dataset when the values are arranged in ascending or descending order. If there is an even number of values, the median is calculated by taking the average of the two middle values. Example: Let's consider the dataset of ages again: 25, 30, 35, 40, and 45. When arranged in ascending order, the middle value is 35. Therefore, the median age in this case is 35.
  • 39. 39 3) Mode: The mode is the value or values that appear most frequently in a dataset. It is not necessarily unique and can have multiple modes or no mode at all. Example: Suppose we have a dataset of test scores: 85, 90, 80, 85, 95. In this case, the mode is 85 since it appears twice, which is more frequently than any other value. 4) Range: The range represents the difference between the highest and lowest values in a dataset. It provides a measure of the spread or variability of the data. Example: Consider a dataset of daily temperatures in degrees Celsius: 10, 15, 12, 18, 20. The highest temperature is 20, and the lowest temperature is 10. Therefore, the range is 20 - 10 = 10 degrees Celsius. 5) Variance: Variance measures the dispersion of data points from the mean. It quantifies the average squared deviation from the mean, providing insight into the spread of data. Example: Let's take the dataset of test scores again: 85, 90, 80, 85, 95. First, calculate the mean (sum of all values divided by the total number of values) which is 87. Then, calculate the squared difference between each score and the mean: (85-87)^2, (90-87)^2, (80-87)^2, (85-87)^2, (95- 87)^2. Find the average of these squared differences. The variance in this case is 16.8. 6) Standard Deviation: The standard deviation is the square root of the variance. It provides a measure of how spread out the values are in relation to the mean. The standard deviation is a widely used measure of variability that indicates how much the data is dispersed around the mean. It provides a more comprehensive understanding of data distribution compared to the variance. Example: Using the same dataset of test scores, the variance was found to be 16.8. Taking the square root of the variance, the standard deviation is approximately 4.1.
  • 40. 40 Section 3: Null Hypothesis and p-value 3.1 Null Hypothesis: The null hypothesis is a statement in research that assumes there is no significant relationship or difference between variables. Researchers typically frame their research in null hypothesis form as it is not possible to prove something with absolute certainty. 3.2 P-value and Hypothesis Testing: The p-value represents the probability of obtaining results as extreme as the observed data, assuming the null hypothesis is true. A p-value less than or equal to 0.05 (commonly referred to as the significance level) is often used to reject the null hypothesis and support the alternative hypothesis. Conclusion: Data preparation and summarization are essential steps in research, enabling researchers to effectively analyze and present their findings. By representing data in frequency tables, charts, and graphs, researchers can visually communicate patterns and trends. Summarization measures such as mean, median, mode, range, variance, and standard deviation provide valuable insights into the central tendency and variability of the data. Furthermore, the null hypothesis and the consideration of the p-value play a critical role in hypothesis testing, ensuring robust and reliable research conclusions. THANK-YOU Dr. Syed M Haroon
  • 41. 41 Conceptual Breakdown The epistemological framework The epistemological framework refers to the philosophical perspective or approach to knowledge and how it is acquired, validated, and understood. It provides the theoretical foundation and assumptions that underlie a research study or inquiry. Epistemology deals with questions such as what constitutes knowledge, how knowledge is acquired, and the criteria for validating knowledge claims. In the context of research, the epistemological framework guides the researcher's understanding of how knowledge is generated and the appropriate methods for investigating a research problem. It shapes the researcher's stance on the nature of reality, the role of the researcher, and the relationship between the researcher and the participants or subjects. There are several common epistemological frameworks used in research, including: 1. Positivism: Positivism is based on the belief that knowledge can be objectively observed and measured. It emphasizes the use of quantitative methods, experiments, and statistical analysis to gather empirical evidence and establish causal relationships. 2. Interpretivism: Interpretivism focuses on understanding and interpreting the subjective meanings, perspectives, and experiences of individuals. It emphasizes qualitative methods such as interviews, observations, and textual analysis to capture the social and cultural contexts in which knowledge is constructed. 3. Constructivism: Constructivism posits that knowledge is actively constructed by individuals through their experiences, interactions, and interpretations. It recognizes the importance of multiple perspectives and context in shaping understanding. Researchers employing constructivism often use mixed methods, combining qualitative and quantitative approaches to capture both individual experiences and broader patterns. These epistemological frameworks influence the research design, data collection methods, data analysis techniques, and the interpretation of findings. It is essential for researchers to explicitly state and justify their chosen epistemological framework to ensure transparency and rigor in their study.
  • 42. 42 TYPE OF RESEARCH: Quantitative Research: A quantitative research example would be a study examining the relationship between sleep duration and academic performance among college students. Researchers might collect data from a large sample of students, measuring their sleep duration using activity trackers and obtaining their academic grades from official records. By analyzing the numerical data, they can determine if there is a correlation between sleep duration and academic performance, allowing them to draw conclusions about the impact of sleep on students' grades. Qualitative Research: An example of qualitative research could be a study exploring the experiences of immigrants transitioning to a new country. Researchers might conduct in-depth interviews with a small group of immigrants, asking open-ended questions about their challenges, emotions, and cultural adaptation process. Through careful analysis of the interview transcripts, they can gain a deeper understanding of the participants' perspectives, their unique experiences, and the factors that influence their adjustment to the new environment. Mixed Methods Research: In a mixed methods research example, let's consider a study on the effectiveness of a teacher training program on student engagement in a primary school. The researchers could administer surveys to both teachers and students to collect quantitative data on various aspects of student engagement, such as attendance, participation, and motivation. Additionally, they could conduct focus group discussions with teachers and students to gather qualitative insights on their perceptions of the training program, the changes they observed, and the factors influencing student engagement. By combining the quantitative survey data analysis with qualitative analysis of the focus group discussions, the researchers can provide a more comprehensive understanding of the program's impact and gather richer insights into the underlying mechanisms contributing to student engagement.
  • 43. 43 Objective: The objective of this research study is to determine which pain management approach, either Intervention A or Intervention B, is more effective in reducing post-operative pain among patients who have undergone appendectomy surgery. In this example, the objective includes elements of measurability, reproducibility, and comparability: 1. Measurability: The objective aims to measure the effectiveness of pain management interventions in reducing post-operative pain. The researchers will use pain rating scales, such as a 0-10 scale, where patients rate their pain level, with 0 being no pain and 10 being the worst pain imaginable. By using this scale, the researchers can quantitatively measure the level of pain experienced by patients in each intervention group. 2. Reproducibility: The objective suggests that the study can be reproduced by other researchers or healthcare professionals to validate the findings. The researchers will provide clear details about the two pain management approaches (Intervention A and Intervention B), including specific protocols and techniques used, so that other healthcare providers can replicate the study in different hospitals or surgical centers. 3. Comparability: The objective aims to compare the effectiveness of Intervention A and Intervention B in reducing post-operative pain. By comparing the pain levels reported by patients in each intervention group, the researchers can determine which approach yields better pain control. This comparison helps healthcare professionals make informed decisions about which pain management approach to use for patients undergoing appendectomy surgery. By incorporating these elements into the research objective, the study can be designed in a way that ensures the results are easily measurable, reproducible, and comparable. This enhances the scientific validity of the research and provides valuable insights for improving pain management strategies in the medical field.
  • 44. 44 Data Variables Defining Data Variables is an important step in research, as it helps to clearly identify and describe the specific data elements that will be collected and analyzed. Here are some examples of defining data variables in different research contexts: 1. Example in Medical Research: Variable: Blood Pressure Definition: The systolic and diastolic pressure measurements, recorded in millimeters of mercury (mmHg), representing the force exerted by blood against the arterial walls. 2. Example in Social Science Research: Variable: Income Definition: The amount of money earned by an individual or household over a specified period, typically measured in a specific currency (e.g., US dollars, euros). 3. Example in Psychological Research: Variable: Anxiety Level Definition: A self-reported or observed measure of the individual's subjective experience of anxiety, often assessed using standardized psychological scales or questionnaires. 4. Example in Educational Research: Variable: Academic Performance Definition: The measure of a student's achievement in academic subjects, usually represented by grades or test scores obtained in specific courses or standardized assessments. 5. Example in Environmental Research: Variable: Air Quality Definition: The level of pollutants, such as particulate matter (PM2.5, PM10), nitrogen dioxide (NO2), or ozone (O3), present in the air within a specific location, measured using specialized monitoring equipment. When defining data variables, it is important to provide clear definitions that precisely describe the nature and units of measurement for each variable. This ensures consistency and understanding among researchers and enables accurate data collection and analysis.
  • 45. 45 Types of study designs: OBSERVATIONAL STUDY ➢ Descriptive study ➢ Analytical Study EXPERIMENTAL STUDY Descriptive Study: Descriptive studies aim to describe and summarize the characteristics, behaviors, or phenomena of interest within a population or sample. They focus on providing a comprehensive account of the variables being studied without intervening or manipulating them. Descriptive studies answer questions such as "What is happening?" or "What is the prevalence or distribution of a particular phenomenon?" Example: A researcher conducts a cross-sectional survey to assess the prevalence of smoking among adults in a specific community. The study involves collecting data from a sample of individuals through questionnaires or interviews to determine the proportion of smokers in the population and their demographic characteristics. Limitation: Descriptive studies do not establish causal relationships or determine cause-and-effect connections between variables. They provide valuable information about the current status or prevalence but cannot explain the reasons behind observed associations or changes. ➢ Descriptive studies 1. Case Series: Case series involve the description and analysis of a series of cases with similar characteristics or outcomes. They provide valuable insights into rare diseases or adverse effects of treatments. For example, a case series could describe a series of patients presenting with a rare autoimmune disorder and provide information about their clinical manifestations, treatment responses, and outcomes. Limitations of case series: - Lack of comparison group limits the ability to establish causality or draw definitive conclusions - Subjective reporting and potential bias in selecting cases - Limited generalizability due to the small sample size and potential for unique or atypical cases 2. Case Report: A case report presents a detailed description of a single patient's diagnosis, treatment, and outcomes. They often highlight unique or exceptional cases that contribute to medical knowledge. For example, a case report might describe a patient who experienced a rare side effect of a medication. Limitations of case reports: - Lack of generalizability due to the focus on individual cases - Subjective reporting and potential for bias in the interpretation of outcomes - Limited ability to establish causality or draw broader conclusions 3. Cross-Sectional Study: Cross-sectional studies collect data from a population at a single time point to determine the prevalence of exposures and outcomes. This design helps identify associations but does not establish causality. For example, a cross-sectional study could assess the prevalence of hypertension (outcome) in a specific population and examine its association with obesity (exposure) based on measurements taken at a single time point.
  • 46. 46 Limitations of cross-sectional studies: - Unable to establish temporal relationships or causality - Susceptible to selection bias, as participants may not be representative of the entire population - Limited ability to study rare outcomes or conditions due to the cross-sectional nature ➢ Analytical studies 2. Observational studies involve observing and collecting data on individuals or groups without intervening or manipulating variables. These studies aim to analyze and understand relationships, associations, or patterns between variables. OR Analytical studies involve analyzing and evaluating data to establish causal relationships or determine the effects of interventions or exposures. These studies often compare groups or conditions to assess the impact of an intervention, treatment, or exposure on outcomes of interest. Example:1 A researcher conducts a cohort study to investigate the association between physical activity and the risk of developing cardiovascular diseases. They follow a group of individuals over time, assessing their activity levels and monitoring the occurrence of cardiovascular events. Example:2 A researcher conducts a case-control study to investigate the association between pesticide exposure and the risk of developing a specific type of cancer. They compare a group of individuals with the disease (cases) to a control group without the disease, examining their history of pesticide exposure to determine if there is an increased risk. Limitation: - Analytical studies may face challenges in establishing causality due to confounding variables or biases. While they can provide evidence of associations, other factors may contribute to the observed relationships. 1. Cohort Study: Cohort studies involve following a group of individuals over time to assess the relationship between exposure (e.g., a risk factor) and outcomes (e.g., disease development). Participants are classified based on their exposure status and followed prospectively. For example, a cohort study could investigate the association between smoking (exposure) and the development of lung cancer (outcome) in a group of individuals. Limitations of cohort studies: - Time-consuming and expensive - Attrition and loss to follow-up may affect the validity of results - Difficult to control for all potential confounding factors 2. Case-Control Study: Case-control studies are retrospective designs that compare individuals with a specific outcome (cases) to individuals without the outcome (controls). Researchers identify past exposures or risk factors in both groups to determine their association with the outcome. For example, a case-control study could examine the association
  • 47. 47 between pesticide exposure (exposure) and the development of Parkinson's disease (outcome) by comparing individuals diagnosed with Parkinson's (cases) to individuals without the disease (controls). Limitations of case-control studies: - Recall bias, as participants may have difficulty accurately recalling past exposures - Difficulty in establishing the temporal relationship between exposure and outcome - Selection bias, as the selection of cases and controls may not be representative of the general population ➢ Experimental Study: Experimental studies involve the deliberate manipulation of variables to evaluate cause-and-effect relationships. Participants are randomly assigned to different groups, such as an experimental group receiving a treatment and a control group receiving a placebo or standard treatment. For example, an experimental study could assess the effectiveness of a new drug (treatment) compared to a placebo in reducing blood pressure (outcome) in individuals with hypertension. Limitations of experimental studies: - Ethical considerations may limit the ability to randomly assign participants or manipulate certain variables - Results may not fully reflect real-world conditions and may have limited Randomized Controlled Trials (RCTs) Randomized Controlled Trials (RCTs) are rigorous experimental study designs used to evaluate the efficacy or effectiveness of interventions, treatments, or preventive measures. Here's an explanation of RCTs along with an example and limitations: 1. RCT Definition: A Randomized Controlled Trial (RCT) is a study design in which participants are randomly assigned to one of two or more groups: an experimental group that receives the intervention or treatment being tested and a control group that either receives a placebo or standard care. The random allocation helps ensure that the groups are comparable, minimizing selection bias and confounding variables. 2. Example of RCT: Let's consider an example of an RCT in the field of medicine. Suppose a new drug is developed to treat a specific medical condition. To evaluate its effectiveness, an RCT is conducted. A group of participants with the medical condition is randomly assigned to either the experimental group or the control group. The experimental group receives the new drug, while the control group receives a placebo or an existing standard treatment. The participants are then followed up for a specified period, and outcomes such as symptom improvement or adverse effects are measured and compared between the two groups. 3. Limitations of RCTs: While RCTs are considered the gold standard for assessing causal relationships and treatment efficacy, they do have some limitations: a. Ethical Considerations: In some cases, it may be ethically challenging or not feasible to include a control group that does not receive any treatment or standard care.