emetics definition, emesis definition, Physiology of vomiting, receptors and zone affected, contraindication, expectorant, definition, classification, mechanism, drug used , uses, mechanism of drug action.

1. EMETICS
&
EXPECTORANT
ROMIT VAISHNAV & RUCHI RAWAT
Definition, mechanism example of drug
contraindication

3. DEFINATION
1. EMESIS- vomiting occurs due to stimulation of emetic center situated in the medulla
oblongata.
Physiology of vomiting-
RECEPTOR ZONE WHERE THEY ACT
5-HT3
Inflammation PGS 5-HT
NK1
D2
OPOID
CB1
CTZ
(Chemoreceptor trigger zone)
GTI 5-HT
5-HT3
D2
M
H
NK
NTS
(nucleus tractus solitarius)

4. PHYSIOLOGY OF VOMITING
CORTEX( psychogenic
stimuli)
Motion – inner ear –
cerebellum
blood
vessels

5. i) CNS (Central nervous system) stimulant drug poisoning.-
Convulsions may be precipitated
ii) Corrosive poisoning-
Risk of perforation and further injury to esophageal mucosa
iii) Kerosine poisoning-
chances of aspiration of the liquid
iv) Phenothiazine or Morphine poisoning-
emetics may fail to act
v) Unconscious patient-
May aspirate the vomitus, because laryngeal reflex is likely to
impaired.
CONTRAINDICATION

6. EXPECTORANT

7. Definition-
COUGH: It is a productive reflux that helps to expel or excrete irritant matter
from the respiratory tract.
IRRITATING COUGH/ NON PRODUCTIVE COUGH: Irrigative cough is a type of
dry cough, which can be caused by colds or irritating dust or gases and
produces some kind of sputum and or other discharge.
PRODUCTIVE COUGH: A productive cough is a type of sputum and exudates
producing cough and is often associated with asthma and bronchitis.
EXPACTORANTS:
These drugs are believed to enhance the bronchial secretion or reduce its
viscosity and facilitating its removal by coughing.

8. COUGH
PRODUCTIVE COUGH NON- PRODUCTIVE COUGH
EXPECTORANTS- Eg. Potassium iodide ANTITUSSIVE – Eg. Codeine
TREATED BY

9. MECHANISM OF ACTION OF EXPECTORANT-

10. Thank you