1. RESUME
Name: Rituparna Nath
Email ID: rituparnanath87@gmail.com
Permanent Address:A9/11/11 Satyen Park,Joka,Kolkata 700104
Current Address: Block AG No 73 Sector II Saltlake Kolkata 700091
Phone No: +919804007214
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OBJECTIVE
Seeking positions with a growth oriented organizations like where in my skills would be a
part of development of the association
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ACADEMIC
PGDM in Clinical research and Regulatory affairs from JU (2011-12)
M.Sc. in Genetic Engineering from WBUT (2010)
B.Sc. in Microbiology (H) from CU (2008)
H.S. With from West Bengal Higher Secondary Board (2004)
Madhyamic with from West Bengal Secondary Board (2002)
EXPERIENCE
Clinical Trial observatory work at IPGME&R on A Randomized Controlled Trial on
Flupirtine versus Tramadol in Knee Osteoarthritis for three months.
Responsibilities handled :
preparing and collecting necessary documents for the ongoing trial
designing Case Report Form
managing approvals that oversee the research and marketing of new and existing drugs.
identifying and assessing the suitability of facilities to be used as the clinical trial site
consulting with Doctors on conducting trial
ensuring that the trial site has the trial materials including the trial drugs.
monitoring the trial through out its duration and regular visit to the trial site.
Verifying the data entered onto the CRFs with patients’ clinical note
Collecting completed CRFs from hospital
Writing visit report and filling
Discussing report with doctors and achieving documents
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ASSIGNMENTS
1. P-mutagenesis in Drosophila-a searching tool for novel gene.
Project Summery
Mobile elements (P-ELEMENT) were first used as a mutagenesis tool that introduces a
molecular tag in the genes of interest. This facilitated subsequent molecular cloning and
eventually promoted molecular analysis of a large number of fly genes. P-elements were
modified to detect genes not only based on a mutant phenotype but rather through
revealing RNA or protein expression patterns (enhancer trap, gene trap). Owing to the
typically imprecise mobilization of the P-elements these enhancer trap or gene trap
insertions also provided means to generate (excision) mutants.
2. 2. Bioinformatics project on Alzheimer’s diseased gene using Drosophila as a model
organism.
Project Summery
My work was regarding presenilin gene (located on chromosome 14) among all genes
responsible for Alzheimer’s disease. The official name of this is ‘presenilin 1’.Out of 59
human neurological genes surveyed, including ‘presenilin gene’,38 appear to be conserved
in Drosophila .so I took the gene that encodes for the protein that seems to be important in
causing Alzheimer’s disease human and introduced it into the fruit fly. Then, by using
bioinformatics software and tools I made a homology report for the conserved sequence of
presenilin gene for both human and Drosophila.
Wet Lab Techniques known:
PCR handling, DNA Isolation, Tissue culture, , Plasmid Rescue Overview, Chromosomal
DNA, Preparation of Competent Cells, Digestion and Ligation, Transformation, Plasmid
DNA Preparation, Preparation of DNA from and Agarose Gel, Expression and
Purification of Protein, different Microbiological lab techniques.
Dry Lab Techniques known:
OMIM (online Mendelian Inheritance in man)
NCBI (National Centre for Biotechnology Information.
ENTREZ, EMBL-EBI, SWISS-PROT
BLAST, FASTA, CLASTRALW
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KEY SKILLS
ICH-GCP Guidelines,
Protocol, Case Report Form and Informed Consent Form designing.
COMPUTER PROEFFICIENCY
Basics, MS Office.
Data bases: NCBI (National Centre for Biotechnology Information.).
ENTREZ, EMBL-EBI, SWISS-PROT, BLAST, FASTA, CLASTRALW
EXTRACURICULAR ACTIVITY
Completed 5th
year in Classical Dance, participated in different competition.
Completed 4th
year in Painting, & participated in different competition.
OTHER DETAILS
Date of Birth: 29/04/1986
Language Known: Bengali, Hindi, English
Location preference: Anywhere