This document discusses functional bowel disorder, also known as irritable bowel syndrome (IBS). IBS is characterized by intermittent and chronic abdominal pain associated with changes in bowel habits. It affects females more than males and commonly affects people during young adulthood. While the exact causes are unknown, theories involve the gut-brain axis, genetic and neurohormonal factors, altered GI motility, bacterial overgrowth, and visceral hypersensitivity. The clinical picture involves abdominal pain related to defecation and changes in stool frequency and consistency. Diagnosis is based on history and examination and can be made using criteria like Manning criteria which looks at links between pain and bowel movements.
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Irritable bowel syndrome ( IBS )
1.
2.
3. Functional Bowel disorder characterized by intermittent &
chronic Abdominal pain associated with change in bowel
habits .
- Worldwide Phenomena
- Female More than male 3:1
- Commonly affect Young adulthood
INTRODUCTION
4. - Unknown
Theories :
- Gut Brain axis - Post-infection
- Psychopathological problems - Genetic involvement
- Central neurohormonal defect
- Neural & Hormonal distribution
- Altered GI motility
- Bacterial overgrowth
- Visceral Hyperalgesia
- Dietary intolerance
Pathogenesis
5. - Abdominal Pain associated with defecation :
- Cramping Pain ‘ variable intensity and location ’
descried as : Burning , cutting , dull
- Increase with Meal & Stress
- Change in stool frequency & consistency
- Diarrhea : occur in the morning ‘almost never at night’
- Constipation : Ribbon or pellet shape stool
- Associated with : Straining , urgency , Tenesmus , passage of mucus
, Bloating & abdominal distention
Clinical picture
8. • Manning Criteria
• Patient likely has IBS when at least 3 of 6 criteria are met with up to 93%
specificity
- Onset of pain linked to more frequent bowel movements
- Looser stools associated with onset of pain
- Pain relived by passage of stool
- Noticeable abdominal bloating
- Sensation of incomplete evacuation more than 25% of the time
- Diarrhea with mucus more than 25% of the time
Diagnosis
10. • Dx made by "Role-out“ Similar Condition :
infection , IBD , Lactose intolerance , Celiac disease , Obstruction , Malignancy
• Also by "Role-out"
Red Flag Symptoms:
Diagnosis
