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www.rmlpathology.com
RML PATHOLOGY
www.rmlpathology.com
About Us:
RML Pathology is committed
to Patient Care, Quality,
Integrity, State of Art
Technology, Innovation,
Ethical practices,
Accountability & Leadership
and Being the best in
whatever we do at every
stage since 1954.
www.rmlpathology.com
Why Choose Us :
Seven Decades of Service Excellence
NABL Accredited Lab since two Decades
State of Art Technology
International Quality Assurance Program
World Class Lab Infrastructure
Professional and Ethical Commitment
www.rmlpathology.com
Our Quality Policy
Our Team, Our Commitment
Diagnostic Excellence
State of Art
Infrastructure
Accurate, Precise Clinical
Diagnostic Testing
Timely Reporting
Ethical Commitment
Compassion, Commitment,
Innovation, Team- Work
Delivering World Class Clinical Diagnostic Services
Committed to Diagnostic Excellence
Continuous Medical Teaching Training
www.rmlpathology.com
Our Lab
Departments
www.rmlpathology.com
Hematology
Hematology is the Study of Blood and Blood Disorders. Hematologist at RML are highly trained
healthcare providers who specialized in disease of the blood and blood components.
State of the art instruments we have in hematology department.
Beckmen Coulter Uni-Cel DxH-800
Sysmex XN-1000
Sysmex XP-100
Stago Satellite Max
Biorad Variant / HPLC
Microsed ESR- Westergreen
BIORAD ID- Incubator & Diamed ID- Gel Centrifuge
BioRad Saxo ID-Reader II
EQUIPMENTS
www.rmlpathology.com
www.rmlpathology.com
Flow Cytometry
The Flow Cytometry Department is equipped with State of Art ten color and Seven Color Beckman
Coulter Flow Cytometers with Kaluza analysis software. The Flow Cytometry Department is actively
engaged in Neoplastic and Non-Neoplastic Disorders like Leukemia and Lymphoma characterization,
DNA ploidy , PNH/FLARE tests, CD4/CD8, NK Cell, Cell cycle Analysis etc. The Navios flow cytometer
offers a solution for advanced cytometry applications with workflows for high throughput lab needs.
Navios delivers Multiple parameters for high complexity assays; sensitivity and resolution; and quality,
reproducible results.
Beckman Coulter NAVIOS
Beckman Coulter FC-500
www.rmlpathology.com
Biochemistry
Clinical Biochemistry Department is fully automated and computerized with Ultra modular Screening
and testing facilities:- such as COBAS 6000, COBAS Integra 400 Plus ,COBAS e411, BioRad D10 ,
BioRad Variant turbo & Roche Electrolyte analyzer which accommodate an extensive range of
test.
Cobas 6000
Cobas e411
Cobas Integra 400+
Roche AVL 9180 Eletrolyte Analyzer
BioRad D-10
BioRad Variant Turbo
Siemen’s ADVIA Centaur
Semi-Auto Analyzer
EQUIPMENTS
www.rmlpathology.com
www.rmlpathology.com
Special Biochemistry
In Special Biochemistry, we are doing various ultra sensitive investigations like Newborn
Comprehensive Profile (28 inborn errors of metabolism), Routine Newborn Metabolic profile, Ultra-
sensitive Vitamin D2/D3 , Drugs of Abuse, various steroid hormone panels, VMA Catecholamine's,
Renal stone analysis, Capillary Electrophoresis, Immunofixation, Free Light Chain assays, Xylose
Absorption Test, etc.
In special biochemistry we have the equipment's like
• Water’s ULC-MS/MS – XEVO TQ-XS
• Agilent Cary 360 FTIR
www.rmlpathology.com
Microbiology
The Microbiology laboratory caters full automation, state of art instruments to keep pace with latest
technology. Laboratory is NABL Accredited to provide high quality reports with accuracy and precise
with best turnaround time.
Here, we have 3 separate sections provided with Biosafety cabinets level 2.
• Bacteriology
• Mycobacteriology
• Mycology
We equipped with
Maldi Biotyper Sirius (Bruker)
Vitek-2 Compact
MYLA
Adagio (BioRad)
MGIT-320 TB Culture System
Aerospray Slide Stainers
BOD Incubators
Bectek MGIT 32
Hi Airflow Air Sampler
EQUIPMENTS
www.rmlpathology.com
www.rmlpathology.com
Histopathology & Cytopathology
The Histopathology Department is equipped with state of art equipment's and is performing more than 10,000
specimen processing and cytology per year. The department is equipped with facilities of Gross photo
Documentation, panel of Histo Chemistry Stains and extensive panel of IHC antibodies. The lab has facility of Frozen
Sectioning and Frozen Immune Histo Chemistry, The lab also has active in-house Tissue Micro Array (TMA ) unit.
The Cytology department has facilities for LBC Processing with HPV Testing by PCR.
Immunohistochemistry
The Immunohistochemistry Department is equipped with multiple machines from VENTANA (Benchmark XT). We
have an extensive panel of around 300 antibodies from various brands like DAKO, VENTANA, BIOGENEX,
INVITROGEN and CELL KRAFT etc.
EQUIPMENTS
Automated tissue processors from Leica: For routine tissue processing.
HistoDream Grossing Station
Milestone MacroPath pro-x Macro Digital Imaging System
Automated slide stainer from Leica
Rotatory microtome devices from Leica.
Centrifuges from Thermo-scientific
Automated LBC Instrument
Cryostat UVCM-1860 from Leica
Automated Tissue Micro Array System( TMA)
www.rmlpathology.com
www.rmlpathology.com
Digital Pathology
We have Roche Digital Pathology Solution combines innovative Hardware, Software and Ventana
Companion Algorithm Image analysis software and work in integrated harmony with full Roche
Diagnostic Portfolio.
Benefits :
• Easier Colleague collaboration
• Faster second opinions
• Improved Remote diagnosis
• Enhanced Accuracy and quantification
www.rmlpathology.com
Immunology And Serology
More than 200 parameters performed in this department that contain most of the rarest parameter governed
by well-trained technician with automated machines like Opentrons. Besides this Ultra modular system also
available of the supporting instrument in this department.
Thermofisher SkanIt Elisa Reader
Opentron
Elisa Washer
Fluorescence Microscope
EQUIPMENTS
www.rmlpathology.com
www.rmlpathology.com
Clinical Pathology
The clinical pathology department is equipped with fully automated instruments for Semen and Urine
analysis and has facilities of phase contrast polarizing microscopy.
Sysmex UF-4000
Beckman Coulter Iris
Cobas U411
SQA V- Gold Semen Analyzer
www.rmlpathology.com
Molecular
We offer testing for SARS-CoV-2, Hepatitis B Virus, Hepatitis C Virus, MTB, Human Immunodeficiency
(HIV) Virus, and Herpes Simplex (HSV) Virus Type II. Other STIs include Human Papillomavirus.
Respiratory pathogens include SARS-CoV-2, Flu A/B, H1NI etc.
GeneXpert® Systems (GX-IV)
The BioFire® FilmArray® 2.0 System
Opentrons OT-2
epMotion® 5070
LightCycler® 96 System
MagNA Pure 96 System
QIAcube
ABI 7500 Real-Time PCR
Rotor Gene Q
VERITI – Thermal Cycler
TwinCubator
BIORAD Gel DOC System
EQUIPMENTS
www.rmlpathology.com
www.rmlpathology.com
Genetics and Molecular Genetics Department
We provide expertise in DNA and molecular genetic testing for both congenital an inherited cancer
syndromes. RML Pathology is leading laboratory in genetic testing which continually strive to develop new
test methods that improve patient care. In Genetic Laboratory we do Automated Karyotyping and
Microarray.
In Genetic and Molecular Genetics Department we have :
• Cyto-vision Automated Karyotyping And FISH System
• Affymetrix Microarray 7G System
www.rmlpathology.com
Genomics and Proteomics
The Genomics and Proteomics Department is highly equipped to provide genetic and genomic diagnostic
testing for congenital and/or developmental disorders by chromosomal microarray and exome sequencing.
Genome sequencing for gene mutations, single-gene disorders, and expression profiling by next-generation
sequencing panels, Genetic variations, SNPs, CNVs in cancer, neurodegenerative, cardiac diseases, etc.,
and pharmacogenomics analysis.
SeqStudio Genetic Analyzer
Affymetrix Microarray 7G System
BioRad Molecular Imager Gel Doc XR
Thermo Scientific Laminar Flow Unit
Eppendorf 5810 High-Speed Cooling Centrifuge
Ion Torrent Genestudio S5 Plus
Ion Torrent Ion Chef System
Ion Torrent ion One Touch ES
Ion Torrent ion One Touch 2
ABI PCR Thermal Cycler
Agilent TapeStaion
EQUIPMENTS
www.rmlpathology.com
www.rmlpathology.com
Information Technology Department
Our Information Technology Department is responsible for providing the infrastructure for automation.
It oversees the maintenance of Lab Instruments, Network, Servers, and Computers, including installing
and upgrading software, ensuring the integrity of the cyber security system, repairing computers and
data lines as needed, and tracking the life- cycles of all hardware for scheduled replacement.
• We have State of Art Data Centers over Penta bytes of Secured Storage
• Cyber Security Cell using latest firewall and End Point Security to ensure Security & privacy of
the organizational data
• Fully automated & Interfaced Laboratory Information Management System (LIS)
• High Throughput Radio Wireless Network Communication Systems
• In-house exchange mailing solutions.
• Equipped with High performance IBM Blade Center Server
• Dedicated Servers for various applications
• Software Validation
www.rmlpathology.com
Quality Control Department
The Quality Department monitors the Pathology as per NABL ISO 15189:2012 Medical Laboratory
Requirement for Quality and Competence and ISO 17043:2010 to evaluate the Pathology performance
against the pre-established criteria by means of inter- laboratory comparison in all the fields. We also
conduct RML-Quality Assurance Program (QAP) to monitor Participant laboratories all over India,
continuing performance, identification of problems in lab and initiation of action for improvement as per ISO
17043:2010.
www.rmlpathology.com
THANK YOU

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RML Mehrotra Pathology.pptx

  • 2. www.rmlpathology.com About Us: RML Pathology is committed to Patient Care, Quality, Integrity, State of Art Technology, Innovation, Ethical practices, Accountability & Leadership and Being the best in whatever we do at every stage since 1954.
  • 3. www.rmlpathology.com Why Choose Us : Seven Decades of Service Excellence NABL Accredited Lab since two Decades State of Art Technology International Quality Assurance Program World Class Lab Infrastructure Professional and Ethical Commitment
  • 5. Our Team, Our Commitment Diagnostic Excellence State of Art Infrastructure Accurate, Precise Clinical Diagnostic Testing Timely Reporting Ethical Commitment Compassion, Commitment, Innovation, Team- Work Delivering World Class Clinical Diagnostic Services Committed to Diagnostic Excellence Continuous Medical Teaching Training
  • 7. www.rmlpathology.com Hematology Hematology is the Study of Blood and Blood Disorders. Hematologist at RML are highly trained healthcare providers who specialized in disease of the blood and blood components. State of the art instruments we have in hematology department. Beckmen Coulter Uni-Cel DxH-800 Sysmex XN-1000 Sysmex XP-100 Stago Satellite Max Biorad Variant / HPLC Microsed ESR- Westergreen BIORAD ID- Incubator & Diamed ID- Gel Centrifuge BioRad Saxo ID-Reader II EQUIPMENTS
  • 9. www.rmlpathology.com Flow Cytometry The Flow Cytometry Department is equipped with State of Art ten color and Seven Color Beckman Coulter Flow Cytometers with Kaluza analysis software. The Flow Cytometry Department is actively engaged in Neoplastic and Non-Neoplastic Disorders like Leukemia and Lymphoma characterization, DNA ploidy , PNH/FLARE tests, CD4/CD8, NK Cell, Cell cycle Analysis etc. The Navios flow cytometer offers a solution for advanced cytometry applications with workflows for high throughput lab needs. Navios delivers Multiple parameters for high complexity assays; sensitivity and resolution; and quality, reproducible results. Beckman Coulter NAVIOS Beckman Coulter FC-500
  • 10. www.rmlpathology.com Biochemistry Clinical Biochemistry Department is fully automated and computerized with Ultra modular Screening and testing facilities:- such as COBAS 6000, COBAS Integra 400 Plus ,COBAS e411, BioRad D10 , BioRad Variant turbo & Roche Electrolyte analyzer which accommodate an extensive range of test. Cobas 6000 Cobas e411 Cobas Integra 400+ Roche AVL 9180 Eletrolyte Analyzer BioRad D-10 BioRad Variant Turbo Siemen’s ADVIA Centaur Semi-Auto Analyzer EQUIPMENTS
  • 12. www.rmlpathology.com Special Biochemistry In Special Biochemistry, we are doing various ultra sensitive investigations like Newborn Comprehensive Profile (28 inborn errors of metabolism), Routine Newborn Metabolic profile, Ultra- sensitive Vitamin D2/D3 , Drugs of Abuse, various steroid hormone panels, VMA Catecholamine's, Renal stone analysis, Capillary Electrophoresis, Immunofixation, Free Light Chain assays, Xylose Absorption Test, etc. In special biochemistry we have the equipment's like • Water’s ULC-MS/MS – XEVO TQ-XS • Agilent Cary 360 FTIR
  • 13. www.rmlpathology.com Microbiology The Microbiology laboratory caters full automation, state of art instruments to keep pace with latest technology. Laboratory is NABL Accredited to provide high quality reports with accuracy and precise with best turnaround time. Here, we have 3 separate sections provided with Biosafety cabinets level 2. • Bacteriology • Mycobacteriology • Mycology We equipped with Maldi Biotyper Sirius (Bruker) Vitek-2 Compact MYLA Adagio (BioRad) MGIT-320 TB Culture System Aerospray Slide Stainers BOD Incubators Bectek MGIT 32 Hi Airflow Air Sampler EQUIPMENTS
  • 15. www.rmlpathology.com Histopathology & Cytopathology The Histopathology Department is equipped with state of art equipment's and is performing more than 10,000 specimen processing and cytology per year. The department is equipped with facilities of Gross photo Documentation, panel of Histo Chemistry Stains and extensive panel of IHC antibodies. The lab has facility of Frozen Sectioning and Frozen Immune Histo Chemistry, The lab also has active in-house Tissue Micro Array (TMA ) unit. The Cytology department has facilities for LBC Processing with HPV Testing by PCR. Immunohistochemistry The Immunohistochemistry Department is equipped with multiple machines from VENTANA (Benchmark XT). We have an extensive panel of around 300 antibodies from various brands like DAKO, VENTANA, BIOGENEX, INVITROGEN and CELL KRAFT etc. EQUIPMENTS Automated tissue processors from Leica: For routine tissue processing. HistoDream Grossing Station Milestone MacroPath pro-x Macro Digital Imaging System Automated slide stainer from Leica Rotatory microtome devices from Leica. Centrifuges from Thermo-scientific Automated LBC Instrument Cryostat UVCM-1860 from Leica Automated Tissue Micro Array System( TMA)
  • 17. www.rmlpathology.com Digital Pathology We have Roche Digital Pathology Solution combines innovative Hardware, Software and Ventana Companion Algorithm Image analysis software and work in integrated harmony with full Roche Diagnostic Portfolio. Benefits : • Easier Colleague collaboration • Faster second opinions • Improved Remote diagnosis • Enhanced Accuracy and quantification
  • 18. www.rmlpathology.com Immunology And Serology More than 200 parameters performed in this department that contain most of the rarest parameter governed by well-trained technician with automated machines like Opentrons. Besides this Ultra modular system also available of the supporting instrument in this department. Thermofisher SkanIt Elisa Reader Opentron Elisa Washer Fluorescence Microscope EQUIPMENTS
  • 20. www.rmlpathology.com Clinical Pathology The clinical pathology department is equipped with fully automated instruments for Semen and Urine analysis and has facilities of phase contrast polarizing microscopy. Sysmex UF-4000 Beckman Coulter Iris Cobas U411 SQA V- Gold Semen Analyzer
  • 21. www.rmlpathology.com Molecular We offer testing for SARS-CoV-2, Hepatitis B Virus, Hepatitis C Virus, MTB, Human Immunodeficiency (HIV) Virus, and Herpes Simplex (HSV) Virus Type II. Other STIs include Human Papillomavirus. Respiratory pathogens include SARS-CoV-2, Flu A/B, H1NI etc. GeneXpert® Systems (GX-IV) The BioFire® FilmArray® 2.0 System Opentrons OT-2 epMotion® 5070 LightCycler® 96 System MagNA Pure 96 System QIAcube ABI 7500 Real-Time PCR Rotor Gene Q VERITI – Thermal Cycler TwinCubator BIORAD Gel DOC System EQUIPMENTS
  • 23. www.rmlpathology.com Genetics and Molecular Genetics Department We provide expertise in DNA and molecular genetic testing for both congenital an inherited cancer syndromes. RML Pathology is leading laboratory in genetic testing which continually strive to develop new test methods that improve patient care. In Genetic Laboratory we do Automated Karyotyping and Microarray. In Genetic and Molecular Genetics Department we have : • Cyto-vision Automated Karyotyping And FISH System • Affymetrix Microarray 7G System
  • 24. www.rmlpathology.com Genomics and Proteomics The Genomics and Proteomics Department is highly equipped to provide genetic and genomic diagnostic testing for congenital and/or developmental disorders by chromosomal microarray and exome sequencing. Genome sequencing for gene mutations, single-gene disorders, and expression profiling by next-generation sequencing panels, Genetic variations, SNPs, CNVs in cancer, neurodegenerative, cardiac diseases, etc., and pharmacogenomics analysis. SeqStudio Genetic Analyzer Affymetrix Microarray 7G System BioRad Molecular Imager Gel Doc XR Thermo Scientific Laminar Flow Unit Eppendorf 5810 High-Speed Cooling Centrifuge Ion Torrent Genestudio S5 Plus Ion Torrent Ion Chef System Ion Torrent ion One Touch ES Ion Torrent ion One Touch 2 ABI PCR Thermal Cycler Agilent TapeStaion EQUIPMENTS
  • 26. www.rmlpathology.com Information Technology Department Our Information Technology Department is responsible for providing the infrastructure for automation. It oversees the maintenance of Lab Instruments, Network, Servers, and Computers, including installing and upgrading software, ensuring the integrity of the cyber security system, repairing computers and data lines as needed, and tracking the life- cycles of all hardware for scheduled replacement. • We have State of Art Data Centers over Penta bytes of Secured Storage • Cyber Security Cell using latest firewall and End Point Security to ensure Security & privacy of the organizational data • Fully automated & Interfaced Laboratory Information Management System (LIS) • High Throughput Radio Wireless Network Communication Systems • In-house exchange mailing solutions. • Equipped with High performance IBM Blade Center Server • Dedicated Servers for various applications • Software Validation
  • 27. www.rmlpathology.com Quality Control Department The Quality Department monitors the Pathology as per NABL ISO 15189:2012 Medical Laboratory Requirement for Quality and Competence and ISO 17043:2010 to evaluate the Pathology performance against the pre-established criteria by means of inter- laboratory comparison in all the fields. We also conduct RML-Quality Assurance Program (QAP) to monitor Participant laboratories all over India, continuing performance, identification of problems in lab and initiation of action for improvement as per ISO 17043:2010.