TB is the leading cause of death among people who are HIV positive. TB would be serious health problem where there is poor sanitation, poverty and illiteracy. In this paper an attempt is made to know 1.Prevalence of TB in four southern states, 2. Risk factors associated with the infection (TB) and 3.Health seeking behavior among the infected person with TB. Data were collected from NFHS-3 for the four selected states viz: Andhra Pradesh, Karnataka, Kerala and Tamil Nadu analyzes and discussed.