Strategies for the management of triple negative breast cancer
1. Editoriale Page 1 of 1
Strategies for the management of triple negative breast cancer
Triple negative breast cancer (TNBC) is a minor subtype and has distinctive aspect of clinical
behavior. TNBC often shows rapid and expanding growth pattern, unlike luminal type.
Chemotherapy is the only method as systemic therapy and shows remarkable effect with
relatively high probability, to the contrary, some of TNBCs show overt progression in a short
period during chemotherapy and develop early recurrence with short survival. Various
molecular targeting therapies are developing, but do not reach our daily practice. So we tried
to explore effective ways of treatment for TNBC from both previous reports and our
experiences in the literature. We need to consider effective treatment strategy for TNBC,
including local therapy as well as systemic therapy with special care.
Bibliographic Reference:
Yagata H et al.: "Current strategy for triple-negative breast cancer: appropriate combination
of surgery, radiation, and chemotherapy", Breast Cancer. 2011 Feb 3. [Epub ahead of print]
Hiroshi Yagata
Department of Breast Surgical Oncology, St. Luke's International Hospital, Tokyo, Japan
http://www.senology.org/Edit_Yagata.htm 05/04/2011
![Editoriale Page 1 of 1
Strategies for the management of triple negative breast cancer
Triple negative breast cancer (TNBC) is a minor subtype and has distinctive aspect of clinical
behavior. TNBC often shows rapid and expanding growth pattern, unlike luminal type.
Chemotherapy is the only method as systemic therapy and shows remarkable effect with
relatively high probability, to the contrary, some of TNBCs show overt progression in a short
period during chemotherapy and develop early recurrence with short survival. Various
molecular targeting therapies are developing, but do not reach our daily practice. So we tried
to explore effective ways of treatment for TNBC from both previous reports and our
experiences in the literature. We need to consider effective treatment strategy for TNBC,
including local therapy as well as systemic therapy with special care.
Bibliographic Reference:
Yagata H et al.: "Current strategy for triple-negative breast cancer: appropriate combination
of surgery, radiation, and chemotherapy", Breast Cancer. 2011 Feb 3. [Epub ahead of print]
Hiroshi Yagata
Department of Breast Surgical Oncology, St. Luke's International Hospital, Tokyo, Japan
http://www.senology.org/Edit_Yagata.htm 05/04/2011](https://image.slidesharecdn.com/edityagata-110405163803-phpapp02/85/Strategies-for-the-management-of-triple-negative-breast-cancer-1-320.jpg)
