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DC (NH/JG) 80969/4
© UCLES 2014 [Turn over
*0510876364*
BIOLOGY 0610/32
Paper 3 Extended October/November 2014
1 hour 15 minutes
Candidates answer on the Question Paper.
No Additional Materials are required.
READ THESE INSTRUCTIONS FIRST
Write your Centre number, candidate number and name on all the work you hand in.
Write in dark blue or black pen.
You may use an HB pencil for any diagrams or graphs.
Do not use staples, paper clips, glue or correction fluid.
DO NOT WRITE IN ANY BARCODES.
Answer all questions.
Electronic calculators may be used.
You may lose marks if you do not show your working or if you do not use appropriate units.
At the end of the examination, fasten all your work securely together.
The number of marks is given in brackets [ ] at the end of each question or part question.
Cambridge International Examinations
Cambridge International General Certificate of Secondary Education
The syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate.
2
0610/32/O/N/14© UCLES 2014
1 Fig. 1.1 is a photomicrograph of a leaf of the tea plant, Camellia sinensis.
A
B
C
D
E
Fig. 1.1
(a) Name A to E.
A ...............................................................................................................................................
B ...............................................................................................................................................
C ...............................................................................................................................................
D ...............................................................................................................................................
E ...........................................................................................................................................[5]
3
0610/32/O/N/14© UCLES 2014 [Turn over
(b) Fig. 1.2 shows a cell from region B of the leaf shown in Fig. 1.1.
F
G
H
J
K
L
Fig. 1.2
Use the letters from Fig. 1.2 to complete Table 1.1.
Write one letter only in each box to identify the function.You may use each letter once, more
than once or not at all.
Table 1.1
function letter from
Fig. 1.2
controls movement of substances into and out of the cell
exerts a pressure to help maintain the shape of the cell
produces sugars using light as a source of energy
withstands the internal pressure of the cell
controls all the activities of the cell
[5]
4
0610/32/O/N/14© UCLES 2014
(c) The enzyme catalase is found in lettuce leaves.
A student investigated the activity of this enzyme by grinding some lettuce leaves and adding
them to a solution of hydrogen peroxide. The volume of oxygen produced was measured until
the reaction stopped.
The student’s results are shown in Fig. 1.3.
0
0
1
2
3
4
5
6
7
20 40 60 80 100 120
×
×
×
×
×
×
×
× × × × × ×
volume of oxygen
collected/cm3
time/s
Fig. 1.3
(i) Describe the results shown in Fig.1.3. You will gain credit if you use the data in your
answer.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
.......................................................................................................................................[3]
5
0610/32/O/N/14© UCLES 2014 [Turn over
(ii) Explain the action of enzymes during a reaction.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
.......................................................................................................................................[3]
[Total: 16]
6
0610/32/O/N/14© UCLES 2014
2 (a) Define the term excretion.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...............................................................................................................................................[3]
Fig. 2.1 is a diagram of a kidney tubule and its blood supply.
1
2
3
4
blood
blood
Fig. 2.1
7
0610/32/O/N/14© UCLES 2014 [Turn over
(b) The concentrations of solutes in the fluids at regions 1, 2, 3 and 4 were determined. The
results are shown in Table 2.1.
Table 2.1
substance
concentration / gdm–3
region 1 region 2 region 3 region 4
glucose 0.9 0.9 0.2 0.0
protein 82.0 0.0 0.0 0.0
salts 8.0 8.0 9.6 16.5
urea 0.2 0.2 0.2 20.0
State the substance or substances in Table 2.1 which:
(i) has molecules which are too large to be filtered;
.......................................................................................................................................[1]
(ii) has molecules which are small enough to be filtered but is completely reabsorbed from
the fluid in the kidney tubule;
.......................................................................................................................................[1]
(iii) increases in concentration as fluid moves along the kidney tubule.
1 ........................................................................................................................................
2 ....................................................................................................................................[1]
(c) State three structures through which the fluid from region 4 passes as it leaves the body.
1 ................................................................................................................................................
2 ................................................................................................................................................
3 ............................................................................................................................................[3]
(d) One role of the kidney is to maintain the concentration of the blood plasma.
Name the process of maintaining constant conditions within the body.
...............................................................................................................................................[1]
[Total: 10]
8
0610/32/O/N/14© UCLES 2014
3 Sewage treatment works use bacteria to digest the waste matter. Waste matter contains complex
organic compounds, such as starch, cellulose, protein and fat.
Fig. 3.1 shows a diagram of a sewage works with an aerobic digestion tank.
The sewage works discharges clean water into a river. Downstream from the sewage works, water
is removed to be used as drinking water for a nearby village.
chlorine solids
removed
solids
removed
grit to
landfill
compressed
air
air
effluent
screens
grit tank
sedimentation
tank
aerobic
digestion
tank
final
sedimentation
tank
chlorination
tank
mixing
paddle
collection
and
pumping
river
Fig. 3.1
9
0610/32/O/N/14© UCLES 2014 [Turn over
(a) Explain the roles of bacteria in the aerobic digestion tank shown in Fig. 3.1.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...............................................................................................................................................[5]
(b) Fig. 3.1 shows that chlorine is added to water before it leaves the sewage treatment works.
Explain why chlorine is added to the water.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...............................................................................................................................................[2]
[Total: 7]
10
0610/32/O/N/14© UCLES 2014
4 Mammals have a double circulatory system. Blood flows between:
• the heart and the lungs
• the heart and the rest of the body (systemic circulation).
(a) Fig. 4.1 shows a cross-section of an artery.
Fig. 4.1
Explain how the structure of an artery, as shown in Fig. 4.1, is related to its functions.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...............................................................................................................................................[4]
11
0610/32/O/N/14© UCLES 2014 [Turn over
Question 4 continues on page 12.
12
0610/32/O/N/14© UCLES 2014
(b) Fig. 4.2 shows the total cross-sectional area of the blood vessels in the systemic circulation. It
also shows the changes that occur in blood pressure and the speed (velocity) of blood in the
different blood vessels.
aorta
mean blood
pressure/kPa
total cross-
sectional area
of the blood
vessels/cm2
speed of the
blood/cm s–1
arteries
arterioles
capillaries
veins
vena cava
tissue fluid
0
0
1000
2000
3000
4000
0
10
20
30
40
50
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
pressure
velocity
aorta vena cava
Fig. 4.2
13
0610/32/O/N/14© UCLES 2014 [Turn over
(i) State the maximum mean blood pressure in the aorta.
.......................................................................................................................................[1]
(ii) Describe how mean blood pressure and speed of blood change with cross-sectional
area of blood vessels, as shown in Fig. 4.2.
blood pressure ...................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
speed of blood ...................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
.......................................................................................................................................[3]
(c) Describe how substances move from the blood in the capillaries into the tissue fluid.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...............................................................................................................................................[3]
(d) Blood flows from arteries into arterioles before entering capillaries.
Explain the role of the arterioles in the skin when a person is very cold.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...............................................................................................................................................[3]
[Total: 14]
14
0610/32/O/N/14© UCLES 2014
5 Fig. 5.1 is a diagram of the human immunodeficiency virus (HIV).
X
Y
cell membrane of host
cell
Fig. 5.1
(a) (i) Name the parts of the virus labelled X and Y.
X ........................................................................................................................................
Y ....................................................................................................................................[2]
(ii) State three ways in which the structure of bacteria differs from the structure of viruses.
1 .........................................................................................................................................
2 .........................................................................................................................................
3 .....................................................................................................................................[3]
15
0610/32/O/N/14© UCLES 2014 [Turn over
Question 5 continues on page 16.
16
0610/32/O/N/14© UCLES 2014
(b) Sub-Saharan Africa has the highest proportion of the population living with HIV in the world.
The World Health Organization estimates both the total number of people who live with HIV
and the total number of people that are newly infected each year.
Fig. 5.2 shows the estimated numbers for sub-Saharan Africa between 1990 and 2010.
Number of people living with HIV, sub-Saharan Africa. 1990–2010
Number of people newly infected with HIV, sub-Saharan Africa. 1990–2010
1990
1991 1993 1995 1997 1999 2001 2003 2005 2007 2009
1992 1994 1996 1998 2000 2002 2004 2006 2008 2010
0
5
10
15
20
25
1990
1991 1993 1995 1997 1999 2001 2003 2005 2007 2009
1992 1994 1996 1998 2000 2002 2004 2006 2008 2010
0
0.5
1.0
1.5
2.0
2.5
3.0
year
year
millions
of people
millions
of people
Fig. 5.2
17
0610/32/O/N/14© UCLES 2014 [Turn over
(i) Summarise the changes between 1990 and 2009 in the number of people living with HIV
and the number of people newly infected with HIV.
number of people living with HIV........................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
number of people newly infected with HIV .........................................................................
...........................................................................................................................................
...........................................................................................................................................
.......................................................................................................................................[4]
(ii) Suggest why in 2010 the number of people living with HIV increased but the number of
newly infected people decreased.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
.......................................................................................................................................[2]
(iii) Describe three ways in which HIV is transmitted from infected to uninfected people.
1 .........................................................................................................................................
...........................................................................................................................................
2 .........................................................................................................................................
...........................................................................................................................................
3 .........................................................................................................................................
.......................................................................................................................................[3]
18
0610/32/O/N/14© UCLES 2014
(iv) Describe the effects of HIV on the immune system.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
.......................................................................................................................................[3]
[Total: 17]
19
0610/32/O/N/14© UCLES 2014 [Turn over
Question 6 begins on page 20.
20
0610/32/O/N/14© UCLES 2014
6 Some pollutants are not broken down easily and remain in the environment for a long time. These
are described as persistent pollutants.
PCBs are a waste material from the manufacturing of electrical insulation. PCBs are one of the
most persistent pollutants in the environment.
Between 1947 and 1976, factories dumped large quantities of PCBs into the Hudson River in the
USA. Studies measured the concentrations of PCBs in the tissues of organisms in a food chain in
the sea near the Hudson River, as shown in Fig. 6.1.
11400–17300
concentrations of
PCBs in arbitrary units
6–45
1.56
0.85
porpoise
herring
zooplankton
phytoplankton
not to scale
Fig. 6.1
21
0610/32/O/N/14© UCLES 2014 [Turn over
(a) (i) Describe the results shown in Fig. 6.1.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
.......................................................................................................................................[3]
(ii) Suggest an explanation for the different concentrations of PCBs in the organisms of the
food chain.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
.......................................................................................................................................[3]
22
0610/32/O/N/14© UCLES 2014
(b) PCBs are toxic to many organisms because they bind to a protein molecule known as AHR.
The Atlantic tomcod, Microgadus tomcod, is a fish that lives in the Hudson River and other
rivers nearby.
90% of the tomcod population in the Hudson River is resistant to the effects of PCBs. This is
because these fish have a different type of AHR compared with other tomcod populations.
(i) Suggest how this resistance came about.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
.......................................................................................................................................[5]
(ii) Scientists predict that the proportion of fish resistant to PCBs will decrease if the
concentration of PCBs in the river decreases.
Suggest reasons why the proportion of fish with the altered AHR protein might decrease.
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
...........................................................................................................................................
.......................................................................................................................................[2]
23
0610/32/O/N/14© UCLES 2014
(c) Describe the problems caused by non-biodegradable plastics in the environment.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...............................................................................................................................................[3]
[Total: 16]
24
0610/32/O/N/14© UCLES 2014
BLANK PAGE
Copyright Acknowledgements:
Figure 1.1 © Ref: C003/5023; Tea leaf, light micrograph; www.sciencephoto.com.
Figure 5.2 © GLOBAL HIV/AIDS RESPONSE – Epidemic update and health sector progress towards Universal Access – Progress Report; 2011;
http://whqlibdoc.who.int/publications/2011/9789241502986_eng.pdf.
Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every
reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the
publisher will be pleased to make amends at the earliest possible opportunity.
Cambridge International Examinations is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of University of Cambridge Local
Examinations Syndicate (UCLES), which is itself a department of the University of Cambridge.

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0610 w14 qp_32

  • 1. This document consists of 23 printed pages and 1 blank page. DC (NH/JG) 80969/4 © UCLES 2014 [Turn over *0510876364* BIOLOGY 0610/32 Paper 3 Extended October/November 2014 1 hour 15 minutes Candidates answer on the Question Paper. No Additional Materials are required. READ THESE INSTRUCTIONS FIRST Write your Centre number, candidate number and name on all the work you hand in. Write in dark blue or black pen. You may use an HB pencil for any diagrams or graphs. Do not use staples, paper clips, glue or correction fluid. DO NOT WRITE IN ANY BARCODES. Answer all questions. Electronic calculators may be used. You may lose marks if you do not show your working or if you do not use appropriate units. At the end of the examination, fasten all your work securely together. The number of marks is given in brackets [ ] at the end of each question or part question. Cambridge International Examinations Cambridge International General Certificate of Secondary Education The syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate.
  • 2. 2 0610/32/O/N/14© UCLES 2014 1 Fig. 1.1 is a photomicrograph of a leaf of the tea plant, Camellia sinensis. A B C D E Fig. 1.1 (a) Name A to E. A ............................................................................................................................................... B ............................................................................................................................................... C ............................................................................................................................................... D ............................................................................................................................................... E ...........................................................................................................................................[5]
  • 3. 3 0610/32/O/N/14© UCLES 2014 [Turn over (b) Fig. 1.2 shows a cell from region B of the leaf shown in Fig. 1.1. F G H J K L Fig. 1.2 Use the letters from Fig. 1.2 to complete Table 1.1. Write one letter only in each box to identify the function.You may use each letter once, more than once or not at all. Table 1.1 function letter from Fig. 1.2 controls movement of substances into and out of the cell exerts a pressure to help maintain the shape of the cell produces sugars using light as a source of energy withstands the internal pressure of the cell controls all the activities of the cell [5]
  • 4. 4 0610/32/O/N/14© UCLES 2014 (c) The enzyme catalase is found in lettuce leaves. A student investigated the activity of this enzyme by grinding some lettuce leaves and adding them to a solution of hydrogen peroxide. The volume of oxygen produced was measured until the reaction stopped. The student’s results are shown in Fig. 1.3. 0 0 1 2 3 4 5 6 7 20 40 60 80 100 120 × × × × × × × × × × × × × volume of oxygen collected/cm3 time/s Fig. 1.3 (i) Describe the results shown in Fig.1.3. You will gain credit if you use the data in your answer. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3]
  • 5. 5 0610/32/O/N/14© UCLES 2014 [Turn over (ii) Explain the action of enzymes during a reaction. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] [Total: 16]
  • 6. 6 0610/32/O/N/14© UCLES 2014 2 (a) Define the term excretion. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] Fig. 2.1 is a diagram of a kidney tubule and its blood supply. 1 2 3 4 blood blood Fig. 2.1
  • 7. 7 0610/32/O/N/14© UCLES 2014 [Turn over (b) The concentrations of solutes in the fluids at regions 1, 2, 3 and 4 were determined. The results are shown in Table 2.1. Table 2.1 substance concentration / gdm–3 region 1 region 2 region 3 region 4 glucose 0.9 0.9 0.2 0.0 protein 82.0 0.0 0.0 0.0 salts 8.0 8.0 9.6 16.5 urea 0.2 0.2 0.2 20.0 State the substance or substances in Table 2.1 which: (i) has molecules which are too large to be filtered; .......................................................................................................................................[1] (ii) has molecules which are small enough to be filtered but is completely reabsorbed from the fluid in the kidney tubule; .......................................................................................................................................[1] (iii) increases in concentration as fluid moves along the kidney tubule. 1 ........................................................................................................................................ 2 ....................................................................................................................................[1] (c) State three structures through which the fluid from region 4 passes as it leaves the body. 1 ................................................................................................................................................ 2 ................................................................................................................................................ 3 ............................................................................................................................................[3] (d) One role of the kidney is to maintain the concentration of the blood plasma. Name the process of maintaining constant conditions within the body. ...............................................................................................................................................[1] [Total: 10]
  • 8. 8 0610/32/O/N/14© UCLES 2014 3 Sewage treatment works use bacteria to digest the waste matter. Waste matter contains complex organic compounds, such as starch, cellulose, protein and fat. Fig. 3.1 shows a diagram of a sewage works with an aerobic digestion tank. The sewage works discharges clean water into a river. Downstream from the sewage works, water is removed to be used as drinking water for a nearby village. chlorine solids removed solids removed grit to landfill compressed air air effluent screens grit tank sedimentation tank aerobic digestion tank final sedimentation tank chlorination tank mixing paddle collection and pumping river Fig. 3.1
  • 9. 9 0610/32/O/N/14© UCLES 2014 [Turn over (a) Explain the roles of bacteria in the aerobic digestion tank shown in Fig. 3.1. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[5] (b) Fig. 3.1 shows that chlorine is added to water before it leaves the sewage treatment works. Explain why chlorine is added to the water. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[2] [Total: 7]
  • 10. 10 0610/32/O/N/14© UCLES 2014 4 Mammals have a double circulatory system. Blood flows between: • the heart and the lungs • the heart and the rest of the body (systemic circulation). (a) Fig. 4.1 shows a cross-section of an artery. Fig. 4.1 Explain how the structure of an artery, as shown in Fig. 4.1, is related to its functions. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[4]
  • 11. 11 0610/32/O/N/14© UCLES 2014 [Turn over Question 4 continues on page 12.
  • 12. 12 0610/32/O/N/14© UCLES 2014 (b) Fig. 4.2 shows the total cross-sectional area of the blood vessels in the systemic circulation. It also shows the changes that occur in blood pressure and the speed (velocity) of blood in the different blood vessels. aorta mean blood pressure/kPa total cross- sectional area of the blood vessels/cm2 speed of the blood/cm s–1 arteries arterioles capillaries veins vena cava tissue fluid 0 0 1000 2000 3000 4000 0 10 20 30 40 50 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 pressure velocity aorta vena cava Fig. 4.2
  • 13. 13 0610/32/O/N/14© UCLES 2014 [Turn over (i) State the maximum mean blood pressure in the aorta. .......................................................................................................................................[1] (ii) Describe how mean blood pressure and speed of blood change with cross-sectional area of blood vessels, as shown in Fig. 4.2. blood pressure ................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... speed of blood ................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] (c) Describe how substances move from the blood in the capillaries into the tissue fluid. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] (d) Blood flows from arteries into arterioles before entering capillaries. Explain the role of the arterioles in the skin when a person is very cold. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] [Total: 14]
  • 14. 14 0610/32/O/N/14© UCLES 2014 5 Fig. 5.1 is a diagram of the human immunodeficiency virus (HIV). X Y cell membrane of host cell Fig. 5.1 (a) (i) Name the parts of the virus labelled X and Y. X ........................................................................................................................................ Y ....................................................................................................................................[2] (ii) State three ways in which the structure of bacteria differs from the structure of viruses. 1 ......................................................................................................................................... 2 ......................................................................................................................................... 3 .....................................................................................................................................[3]
  • 15. 15 0610/32/O/N/14© UCLES 2014 [Turn over Question 5 continues on page 16.
  • 16. 16 0610/32/O/N/14© UCLES 2014 (b) Sub-Saharan Africa has the highest proportion of the population living with HIV in the world. The World Health Organization estimates both the total number of people who live with HIV and the total number of people that are newly infected each year. Fig. 5.2 shows the estimated numbers for sub-Saharan Africa between 1990 and 2010. Number of people living with HIV, sub-Saharan Africa. 1990–2010 Number of people newly infected with HIV, sub-Saharan Africa. 1990–2010 1990 1991 1993 1995 1997 1999 2001 2003 2005 2007 2009 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 0 5 10 15 20 25 1990 1991 1993 1995 1997 1999 2001 2003 2005 2007 2009 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 0 0.5 1.0 1.5 2.0 2.5 3.0 year year millions of people millions of people Fig. 5.2
  • 17. 17 0610/32/O/N/14© UCLES 2014 [Turn over (i) Summarise the changes between 1990 and 2009 in the number of people living with HIV and the number of people newly infected with HIV. number of people living with HIV........................................................................................ ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... number of people newly infected with HIV ......................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[4] (ii) Suggest why in 2010 the number of people living with HIV increased but the number of newly infected people decreased. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2] (iii) Describe three ways in which HIV is transmitted from infected to uninfected people. 1 ......................................................................................................................................... ........................................................................................................................................... 2 ......................................................................................................................................... ........................................................................................................................................... 3 ......................................................................................................................................... .......................................................................................................................................[3]
  • 18. 18 0610/32/O/N/14© UCLES 2014 (iv) Describe the effects of HIV on the immune system. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] [Total: 17]
  • 19. 19 0610/32/O/N/14© UCLES 2014 [Turn over Question 6 begins on page 20.
  • 20. 20 0610/32/O/N/14© UCLES 2014 6 Some pollutants are not broken down easily and remain in the environment for a long time. These are described as persistent pollutants. PCBs are a waste material from the manufacturing of electrical insulation. PCBs are one of the most persistent pollutants in the environment. Between 1947 and 1976, factories dumped large quantities of PCBs into the Hudson River in the USA. Studies measured the concentrations of PCBs in the tissues of organisms in a food chain in the sea near the Hudson River, as shown in Fig. 6.1. 11400–17300 concentrations of PCBs in arbitrary units 6–45 1.56 0.85 porpoise herring zooplankton phytoplankton not to scale Fig. 6.1
  • 21. 21 0610/32/O/N/14© UCLES 2014 [Turn over (a) (i) Describe the results shown in Fig. 6.1. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3] (ii) Suggest an explanation for the different concentrations of PCBs in the organisms of the food chain. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[3]
  • 22. 22 0610/32/O/N/14© UCLES 2014 (b) PCBs are toxic to many organisms because they bind to a protein molecule known as AHR. The Atlantic tomcod, Microgadus tomcod, is a fish that lives in the Hudson River and other rivers nearby. 90% of the tomcod population in the Hudson River is resistant to the effects of PCBs. This is because these fish have a different type of AHR compared with other tomcod populations. (i) Suggest how this resistance came about. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[5] (ii) Scientists predict that the proportion of fish resistant to PCBs will decrease if the concentration of PCBs in the river decreases. Suggest reasons why the proportion of fish with the altered AHR protein might decrease. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... .......................................................................................................................................[2]
  • 23. 23 0610/32/O/N/14© UCLES 2014 (c) Describe the problems caused by non-biodegradable plastics in the environment. ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ...............................................................................................................................................[3] [Total: 16]
  • 24. 24 0610/32/O/N/14© UCLES 2014 BLANK PAGE Copyright Acknowledgements: Figure 1.1 © Ref: C003/5023; Tea leaf, light micrograph; www.sciencephoto.com. Figure 5.2 © GLOBAL HIV/AIDS RESPONSE – Epidemic update and health sector progress towards Universal Access – Progress Report; 2011; http://whqlibdoc.who.int/publications/2011/9789241502986_eng.pdf. Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the publisher will be pleased to make amends at the earliest possible opportunity. Cambridge International Examinations is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of University of Cambridge Local Examinations Syndicate (UCLES), which is itself a department of the University of Cambridge.