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Introduction to Dosage
Form Design
Abubakr O. Nur (M.Pharm; PhD)
Assoc. Prof. in Pharmaceutics (U of K)
August 2010
Introduction
• What the course aim at?
• What are pharmaceutical
processing, drug formulation and
biopharmaceutics?
• Why DS or a dosage form for a
drug?
2Dr. Abubakr O. Nur
• You are already familiar with the
following terms:
–Route of administration,
bioavailability, bioequivalence,
biopharmaceutics, rate and extent
of drug absorption, onset of drug
action, first pass effect, dissolution
and disintegration. Are you?????
3Dr. Abubakr O. Nur
• In fact, to design a dosage form
three factors contribute similarly.
1. Dosage form related factors
2. Drug related factors
3. Physiological factors
4Dr. Abubakr O. Nur
Dosage forms to be considered are:
– Solid dosage forms (tablets and capsules)
– Liquid dosage forms (solution, suspensions and
emulsions)
– Gas delivery (aerosols and inhalations)
– Semisolid delivery systems (dermatological
products)
– Products for Transdermal applications (skin
patches)
– Sustained and novel DDS.
– Sterile products
5Dr. Abubakr O. Nur

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Lect 1 introduction_to_dosage_form_design_

  • 1. Introduction to Dosage Form Design Abubakr O. Nur (M.Pharm; PhD) Assoc. Prof. in Pharmaceutics (U of K) August 2010
  • 2. Introduction • What the course aim at? • What are pharmaceutical processing, drug formulation and biopharmaceutics? • Why DS or a dosage form for a drug? 2Dr. Abubakr O. Nur
  • 3. • You are already familiar with the following terms: –Route of administration, bioavailability, bioequivalence, biopharmaceutics, rate and extent of drug absorption, onset of drug action, first pass effect, dissolution and disintegration. Are you????? 3Dr. Abubakr O. Nur
  • 4. • In fact, to design a dosage form three factors contribute similarly. 1. Dosage form related factors 2. Drug related factors 3. Physiological factors 4Dr. Abubakr O. Nur
  • 5. Dosage forms to be considered are: – Solid dosage forms (tablets and capsules) – Liquid dosage forms (solution, suspensions and emulsions) – Gas delivery (aerosols and inhalations) – Semisolid delivery systems (dermatological products) – Products for Transdermal applications (skin patches) – Sustained and novel DDS. – Sterile products 5Dr. Abubakr O. Nur