The document discusses aging (Jara) from an Ayurvedic perspective. It covers the criteria of aging, including the shift from communicable to chronic diseases over 200 years. Lifestyle factors and dietary habits are major impacts on aging. It describes the decade-wise aging process according to Ayurveda and lists the chief complaints associated with aging.

3. By
Dr. Nutan Panda

4. INTRODUCTION
“THE GOAL OF LIFE IS TO DIE YOUNG AS
LATE AS POSSIBLE”
-Asle Montegue
1) Ayurveda , deals with physical, psychological as well as spiritual well
being of an individual.
2) The desire to live is common to all living creatures evolved on this
graceful planet, the Earth.
3) Man, is a step ahead in the sense, desires not only to live but to live
a long, happy and disease free life as far as possible.

5. CRITERIA OF TOPIC SELECTION
200 YEARS AGO TODAY
COMMUNICABLE DISEASES CHRONIC DISEASE (like
HT, DM, Cancer etc.)
1)World shifting from young to old world.
2)Incorrect life style &dietary habits.
3)Increase stress in day to day life.
4)Elderly population in India by 2016 will be 113 million i.e.10-12 % of whole
population
The present study undertaken is designed with the hypothesis that
Stress, incorrect Life style & Dietary Habits have found to be major impacts on
Ageing. 5

6. LIFE EXPECTANCY OF THE WORLD
India-67.5-
70yrs
SWEDAN
CANADA
RUSSIAN FEDERATION
UK
USA
JAPAN
CHINA
MEXICO
INDIA
AFHGANISTAN
BRAZIL
ANGOLA &
ZAMBIA AUSTRALIA
ARGENTINA
6

7. JARA:- An Ayurvedic Review

8. Etymology of Jara
Jara (old age) is from root “t`”k o;ksgkukS”
by applying the sutra ^^f”kfnkfnH;ksMM~-
** the term indicates to the loss in the period of
life span. The deduction from the remaining half
of the expected duration and every spent year
would be considered as a loss in the age.

9. Synonyms of Jara & Vriddha
OF JARA (Sources: Vachaspatyam and Gurubala prabodhika)
LFkfoje~ & LFkfoja rq o`)Roe~ -The aspect of being old
foL=lk & folzalrs v/k%irfrA -The degeneration of the
Shareera
OF VRIDDHA
o`)% & o/kZrs o`)% -One who has already attained Vriddhi.
izo;% & izxra ;kSouk[;a o;ks·L;sfr izo;%-One who has crossed his
youth.
LFkfoj% & cgq dkya fr”Brhfr LFkfoj%- One who has stayed for a
long time.
thu% & thufr o;lks gh;rs thu%-One who is attaining deterioration.
th.kZ@tju~ & th;rs th.kZ% tjp -Same meaning.
T;k;u~% & o”khZ;ku~ n’kfe T;k;u~ -One who is at the stage of 90
years.
tfjr% & t’k tkr vL; rkjdkA

10. Types of Jara
Kalaja Jara:
Jara coming at the proper age is Kalaja Jara(after 60 yrs.). It is
‘Parirakshana Krita’ means it occurs at the proper age even after following the daily
and seasonal regimen mentioned in Swasthavritta. This is nothing but chronological
Ageing. Dhatu kshaya janya jara.
Akalaja Jara – The Concept of Premature Ageing:
‘ Akalotpanna lakshana Akalaja’, ‘ Akale jata iti Akalaja’
means that thing which occurs Akalaja i.e. before its prescribed time. occurs before
the proper age due to not taking the proper care of personal hygiene
(Swasthavritta). This Akalaja Jara is of greater intensity, rapidly progressing one if
neglected. This is Biological Ageing. Marga avarodha janya jara.

11. CAUSES OF JARA ACCORDING TO AYURVEDA
iUFkk% ‘khra dnUukfu o;kso`)k’p ;ksf”kr%A
eul% izkfrdwY;a p tjk;k% ip gsro%A ¼j-j-l-26@2½
In Ras Ratna Samucchaya. The etiological
factors of Akalaja Jara described are :-
Continuous walking after tiredness
Intake of unwholesome food
Intake of cold substances
Staying in cold house
Sexual indulgence with an old woman
Pressure of mind because of unbearable affairs.

12. Etiological Factors of Ageing Related to Dietary Habits
“we are what we eat”
1. Lavana (salt), Amla (sour), Katu (spicy) rasa pradhana
2. Kshara (alkali)
3. Suska shaka & Mamsa (dry vegetable & Meat)
4. Tila Samyoga
5. Pista Anna
6. Viruddha Anna (Incompatible Diet)
7. Asatmya Anna (Unfavorable Diet)
8. Ruksha Anna (Dry Cereal)
9. Abhisyandi Anna
10. Klinna & Guru Anna (Heavy Diet)
11. Puti & Paryushita Anna (Polluted & Out dated Diet)
12. Vishamashana (Improper Eating Habits)
13. Adhyashana (Over Eating) 12

13. Etiological Factors Related to
Life style:
1. Atimarga Gamana (Excessive Walk)
2. Diwa Swapna (Day Sleeping)
3. Nitya Stri Sevana (Excessive Intercourse)
4. Nitya Madya Sevana (Excessive Intake of Alcohol)
5. Vishama Vyayama Sevan (Improper Exercise)
13

14. The etiological factor of Ageing related to disturbed
Mental Health
1. Bhaya (Fear)
2. Krodha (Anger)
3. Shok (Sorrow)
4. Lobha (Greed)
5. Moha (Affection)
6. Ruksha Vani (Harsh words)
7. Kalah Priya Bharya (Quarrelsome Wife)
8. Kuputra/ Kuputri (Maladroit child)
14

15. Ageing
Srotokhar
Vata atwa
vriddhi (srotovah
ani)
Improper
Ojo How Vata absorption
&
vriddhi occurs assimilation
kshaya of ahara
during ageing? rasa
Uttarota Disequilibr
ium in
ra dhatu upchaya &
kshaya apchaya
Rasa
dhatu
kshaya

16. Etiopathogenesis of Ageing
Disturbances in Manasika Bhava
Dosha
Rajas Dushti, Tamas, satva
(Bhaya ,krodha, Shok ,Lobha, Moha )
Vikrit Agni
Mana Dushti
Ajirna/Agnimandya
Ama
Free radicals
Injury to cells
Gradually damage to all over cell
Ageing

17. DECADE WISE AGEING PROCESS
Vagbhatta was the first one to record such an observation, which was followed later
by Sharangadhara.
ckY;a o`f)% NfoZes?kk RoXn`f”V% ‘kqdzfodzekSA
c`f)% desZfUnz;a psrks thfora n’krks g`lsr AA ¼’kk-la-iw-6@20½
ckY;s o`f)a izHkkes/kkRod ‘kqdzkf{k=qrhfUnz;e~A
n’kds”kq dzek?kkfUr eu% losZfUnz;kf.k pAA ¼v-la-‘kk-8@25½
It is clear that ageing does not occur simultaneously in all the tissues. Different
body tissues are affected ageing at different time period. Gradual declination of a
particular faculty takes place in each decade of life and by the end of decade, that
particular faculty is lost.
Decade Loss of tissues
Vagbhata Sharngadhara
I Childhood Childhood
ΙΙ Growth Growth
ΙΙΙ Complexion Complexion
IV Intellect Intellect
V Skin Skin
VI Reproductive Capacity Vision
VII Vision Reproductive Capacity
VIII Hearing Valour
IX Mind Knowledge
X Sensory & Motor organs Motor organs
XI - Mind
XII - Life

18. CHIEF COMPLAINTS
1.Twak Parushata (Dryness of skin) 14. Medha hani (Decreased functions of
2. Slatha sara (Flabbiness Intellect)
of the body) a. Grahana (Grasping Power)
3. Slatha Mamsa (Decreased muscle b. Dharana (Retention Power)
tone) c. Smarana (Memory Power)
4. Slatha Asthi (Bone d. Vachana (Speech)
weakness) e. Vijnana (Knowledge)
5. Slatha Sandhi (Flaccid
joint) 15. Utsaha hani (Decreased Enthusiasm)
6. Dhatu Kshaya (Loss of 16. Parakrama hani (Decreased Physical
Strength)
tissues)
17. Paurusha hani (Decreased Virility)
7. Kayasya Avanamanam (Bending of the
body) 18. Prabha hani / Chhavi Hras (Changes
in Complexion)
8. Vepathu (Tremors)
19. Shukra Kshaya
9. Khalitya (Falling of hairs)
20. Dristi Hras (Diminished Vision)
10. Vali (Wrinkling)
21. Karmendriya hani (Decreased Loco
11. Palitya (Graying of hairs) motor Activities)
12. Kasa (Coughing) 22. Buddhi hani (Deterioration in
13. Shwasa (Short breath) Wisdom)
18

19. Ageing Process :- A Modern Review

20. History of Geriatrics
Greek word “geros” mean the old age + Iatric mean the
medical treatment. This is the branch of medicine concerned with the
problems of Ageing, including physiological, pathological, and
psychological problems.
Nascher was the first to coin the term Geriatrics. He
published a paper in New York medical journal in1909 and a textbook
on it in 1914.
Thus Geriatric came to be recognized as a special
branch in first decade of 20th century.

21. Definition of Ageing
“The processes that occur during life which culminate in changes that
decrease an individual's ability to cope with biological changes”.
GERIATRICS: - A branch of medicine dealing exclusively with the problems of
ageing and the diseases of the elderly. It is derived from the Greek root “ger-
gero- geronto” meaning “old age” or “the aged”.
SYNONYMS OF AGEING:
Senescence: is the process by which the capacity for cell division, growth and
function is lost over time, ultimately leading to an incompatibility with life i.e., the
process of senescence terminates in death.
Senility: This term is from the Latin origin ‘senilitus’, which means the period of
physical and mental deterioration, associated with old age.
Senium: Identical to the term senility, one more term senium is also used in the
medical field; it is marked by the deterioration and weakness that may
accompany the age advancement.
Geria: This also indicates the old age.

22. CLASSIFICATION OF AGE
AGE
Chronological age Biological age – Psychological age
- number of years age by body – age how
lived function individuals feels it
CHRONOLOGICAL CATEGORIES
•Young-Old - (ages 65 - 74) Set Old Age
•Middle-Old - (ages 75 - 84) Old Old Age
•Old-Old - (age 85 and older) Ripe Old Age

23. CLASSIFICATION OF CAUSES OF AGEING
oIMPROPER DIET
Acidic foods
Food additives: Food additives are added to improve the shelf life
and stability of processed and smoked foods, but these are not "body
friendly".
Food preparation: oily food preparation
oIMPROPER LIFESTYLE
oSmoking
oAlcohol
oIrregular sleeping pattern
oPhysical inactivity or improper exercise
oSTRESS
oEXOGENOUS AGENTS
•Environmental pollution: - People living in any metropolitan area are
exposed to pollution, and if regularly commute in traffic jams or live near any
industrial areas, body is exposed to more harmful air particles, and increased
production of free radicals.
•Pesticides: - pesticides causes more oxidative stress in the body.
•Sun exposure
•X-rays
DRUG ABUSE

24. EFFECT OF STRESS ON BODY SYSTEMS

25. Some Theories of Ageing are given below:
Waste Accumulation Theory
Limited Number of Cell Divisions Theory
Hay flick Limit Theory
Death Hormone Theory (DECO)
Thymic -Stimulating Theory
Mitochondrial Theory
Errors and Repairs Theory
Redundant DNA Theory
Cross-Linkage Theory
Autoimmune Theory
Caloric Restriction Theory
Gene Mutation Theory
The Rate of Living Theory
Order to Disorder Theory
The Telomerase Theory of Ageing
Neuro Endocrine theory or Weak Link Theory
Free Radical Theory of Ageing
25

26. FREE RADICAL THEORY
"Free radical" is a term used to describe any molecule that differs from
conventional molecules in that it possesses a free electron, a property that makes
it react with other molecules in highly volatile and destructive ways. The changes
induced by free radicals are believed to be a major cause of Ageing, disease
development or/and death

27. EFFECT OF FREE RADICAL DAMAGE

28. Free Radical Ama
Stress Disturbed Manasika
Bhava
Exogenous Causes- Pollutants, dangerous Paryavaran pradushan/
Chemicals , certain products Mithya Ahara Vihara
Endogenous Causes- Due to deficiency of certain Mandagni
enzymes
Atom/Molecule containing one or more unpaired Apachyamana
electron,
Inassimilable to body components & exist in free state. Visha Rupam
Cause damage to cell membrane & destroy cells, Durgandhatvam
leads to putrefaction & foul smell generation. Suktatvam
Quickly interact with healthy molecules of the body Reaction of aam vish with
thus setting chain reaction. normal cells/ Aashukari
Impaired action of Free Radicals Scavengers Dhatvagni Daurbalya
Increased production at the site Ama Sanchaya
Circulation in the body Prasara
Starts reacting to the weak cell membrane Sthana sanshraya at the
site of Khavaigunya
Production of Sign & Symptoms of Ageing Production of Sign &
Symptoms of Jara

29. CHANGES OCCURING DURING AGEING
29

30. 30

31. 31

32. 32

33. 33

34. Selected Age-related Changes and their consequences
34

35. ANTI AGEING THERAPIES
1. Deprenyl
2. Human Growth Hormone
3. DHEA
4. Melatonin
5. Acetyl-L-Car nitine
6. Coenzyme Q10
7. Alpha Lipoic Acid
8. Cysteine and Procysteine
9. NADH
10. Lycopene
11. Vitamin E
12. Vitamin B5 (Pantothenic Acid)
13. Vitamin B6 (Pyridoxine)
14. Synthetic Antioxidants
15. Levodopa (L- Dopa)
16. Calorie Restriction (can be correlate with “astha aahar
vidhi visheshytan”)
35

36. CONCEPT OF RASAYANA

37. RASAYANA
“Rasasya Ayanam Rasayanam”
jlL; v;ua izki.ka jlk;ue~ ¼jk-fu-½
The Therapy, which gives the benefit of
good Rasa, is Rasayana. Hence, it is the
therapy by which one gets the Rasa, Raktadi
Dhatus of optimum quality.

38. DEFINATION
jlk;urU=a uke o;% LFkkiuek;q esZ/kkcydja
jksxkigj.ke leFkZapA ¼lq-lw-1@7@2½
Rasayana Tantra is one which deals
with delaying of ageing process, increasing of
intellect and strength, prolongation of life and curing
of disorders.

39. S. No Classification Types Of Rasayana
1. Main division Dravyabhuta Adravyabhutas
Rasayana Rasayana
2 As per method Kuti Praveshika Vatatapika Droni- praveshik
of use (Charak)
3 As per Scope of use Kamya Rasayana NaimittikaRasayana Ajasrika Rasayana
Prana Kamya
Medha Kamya
Shri Kamya
4 As per content of Ahara Rasayana Aushadha Rasayana Achara Rasayana
Rasayana (Dietary Rasayana) (Medicinal Rasayana) (Conduct of Rasayana)
5 Specific Rasayana Medhya Rasayana Achara Rasayana
drugs & measures Buddhi Medha
Vardhaka
Ayu Vardhaka
6 According to Samshodhana Samshamana
Prabhava Rasayana Rasayana
7 According to Ritu Satmya Desh Satmya
Satmya Aadana Kala Sadharana Desha
Visarga Kala Jangala Desha
Anupa Desha
8 According to (1)Rasa (2) Rakta (3) Mamsa (4) Meda (5) Asthi (6) Majja
Sapta Dhatus (7) Shukra
9 According to Modern To Promote To improve To improve endocrine and
Medical Science Immunity metabolism exocrine secretions

40. PROBABLE MODE OF ACTION OF RASAYANA
Four Modes of Action of Rasayana
Rasayana basically promotes the nutrition through four modes.
They are:
1. By directly enriching the nutritional intake of the body through
increasing the consumption of Amalki, Satavarai, Milk, Ghee,
etc
2. ON AGNI: By improving Agni i.e. digestion and metabolism
through Bhallataka, Pippali etc, thereby promoting nutrition.
3. SROTOVISHODHANA : By promoting the capability of Srotas
or microcirculatory channels in the body, through herbs like
Haritaki, Guggulu, Tulsi, and so on
4. By its VISHAGHNA property

41. Procedure & effect of Rasayana intake
Sodhankarma
Srotonirmalta Peyadikarma
Kayagni deepti
Dhatu suddhi
Dhatwagni deepti
RASAYAN PRAYOGA
Improved quality of dhatus
OJOVRIDDHI
Longevity and health Immunity Mental competence
REJUVENATION
41
“Yajj jara vyadhi vidhvasi bheshajam tad rasayanam”

42. EFFECT OF RASAYANA
The word Rasayana =Rasa +Ayana.
Rasa: means the Rasa dhatu and the remaining dhatu
Rakta , Mamsa , Meda, Asthi, Majja and Sukra.
Ayana: Ayana means the road, a path, a way and a movement.
“Rasasya Ayanam Rasayanam “
“Labho payo sashtanam rasadinam rasayanam”(ch.chi.1.)
The Therapy, which gives the benefit of good Rasa, is Rasayana. Hence, it is the
therapy by which one gets the Rasa, Raktadi Dhatus of optimum quality.
In short Rasayana -
Gives Long life
Delays Ageing and death
Increase intelligence, memory and luster
Excellence in the body tissues
Increases the immunity
Removes diseases
Gaining “Moksha” (Final Entity) and “Divya Lakshana”

44. RASAYANA YOGA GHNA VATI
The Rasayana yoga for research work comprises of six medicines viz.
1) Ashwagandha
2) Aamalki
3) Bala
4) Guduchi
5) Yashtimadhu
6) Vanshalochan
References for above 1. to 5. medicine are taken from “MEDICINAL PLANTS
IN GERIATRIC HEALTH CARE” an evidence based approach of Central Council for
Research in Ayurveda and Siddha (CCRAS)..
44

45. PHARMACOLOGICAL ACTIVITIES OF DRUGS
1) Aamalki:-(Embelica officinale)
RASA - MADHURA KASAYA TIKTA KATU
GUNA - GURU RUKSHA SHEETA
VEERYA - SHEETA
VIPAKA - MADHURA
PRABHAVA - RASAYANA
DOSA-PRABHAVA -TRIDOSA SHAMAKA PITTA
CNSdepressant, Hypolipidemic, Antiatherosclerotic, Antimicrobial, Antioxidant,
Immunomodulator, Hypoglycemic, Anti-inflammatory, Antitumor.
2)Ashwagandha :-(Withania somnifera)
RASA - TIKTA,KATU,MADHUR
GUNA - LAGHU,SNIGDHA
VEERYA - USHNA
VIPAKA - MADHUR
PRABHAVA - RASAYANA
DOSA-PRABHAVA - KAPHAVATA SHAMAK
Hypotensive, Immunomodulator, Adaptogenic, Antistress, CNSdepressant,
Antioxidant, Analgesic, Antiarthritic, Cardioprotective, Antiageing, Psychotropic.
45

46. 3)Guduchi:-(Tinosporia cordifolia)
RASA - KASAYA TIKTA
GUNA - GURU SNEEGDHA
VEERYA - USHNA
VIPAKA - MADHURA
PRABHAVA - RASAYANA
DOSA-PRABHAVA- TRIDOSA SHAMAKA
Hypoglycemia, Antihyperglycemic
, CNSdepressant, antistress, Hepatoprotective, antiarthritic, Antiallergic
Immunostimulant, Antidiabetic, Adaptogenic, Antioxidant, Diuretic.
4)Bala:-(Sida cordifolia)
RASA - MADHURA
GUNA - LAGHU, SNEEGDHA,PICHILA
VEERYA - SHITA
VIPAKA - MADHURA
PRABHAVA - RASAYANA
DOSA-PRABHAVA- VATA PITTA SHAMAKA
Antioxidant, Thyroregulatory ,Hepatoprotective, Immunomodulatory,
Antihypertensive, Hypoglycemic, Adaptogenic.
46

47. 5)Yashtimadhu:-(Glycirrihza glabra)
RASA - MADHURA
GUNA - GURU SNEEGDHA
VEERYA - SHITA
VIPAKA - MADHURA
PRABHAVA - RASAYANA
DOSA-PRABHAVA- VATA PITTA SHAMAKA
Hypolipidaemic, Antiatherosclerotic ,Hypotensive, Hepato- protective,
Antiexudative, Antioxidant, Anti-inflammatory
6)Vanshalochana:-(Bambusa arundinacea)
RASA - KASAYA MADHURA
GUNA - GURU SNEEGDHA
VEERYA - SHITA
VIPAKA - MADHURA
DOSA-PRABHAVA- VATA PITTA SHAMAKA
Antidiarrhoel, Antiparalytic, Carminative, Expectorant, It is cooling, nutritive,
stimulant, digestive, aphrodisiac and febrifuge agent. It is known to help in chronic
and general debility, cough and indigestion.
47

48. DRUG PROPERTIES
DRUGS PRABHAVA KARMA DOSHAGHNATA
Amalki Rasayana, Rasayana,Hridya,Vrishya, Nadibalya,Deepaniya, Tridhosh shamak ,
Vrishya Medhya, Anulomana, Shramahara, Balya, Esp. Pitta-shamaka
Vayasthāpana, Jivaniya, Sarvadoshahara, Nadi-
Indriya
Balaprada, Rochana,
Ashwa Rasayana, Balya, Brihana, Rasayana, Vajikarana, Nidrajanan Vata Kapha
gandha Vrishya Shamak
Bala Vrishya, Balya, Vatahara, Hridya, Shukral, Prajasthapan,
Rasayana Vata- pitta shamak
Guduchi Vrishya, Rasayana ,Deepana, Pachana, Balya, Medhya Tridhosh shamak
Rasayana Raktashodhana, Vayasthapana, Vrishya,Pathya,
Shukra dourbalya, Dhatukrita, Shramahara,
Mutrajanana
Yashti madhu Rasayana, Rasayana, Balya, Nadibalya, Medhya,
Vrishya, Keshya,Swarya,Vedanasthapana Vata -pitta Shamak
Vansha Balya, Vrishya, Shamak, Trishnanigrahana, Grahi, Hridya,
lochana Brihana Shwasahara, Mootrala, Jwarghna, Balya, Vata- pitta Shamak
Brimhan

49. RASAYANA YOGA GHANA VATI
PERCENTAGE OF RASA PANCHAKA
S. No. RASA PROPERTIES PERCENTAGE
1. RASA Madhura 38.46 %
Amla 07.69 %
Katu 15.38 %
Tikta 23.07 %
Kashaya 15.38 %
2. GUNA Guru 20.00%
Laghu 20.00%
Sheeta 06.67%
Snigdha 26.67%
Ruksha 13.33%
Picchila 06.67%
Tikshna 06.67%
3. VEERYA Sheeta 66.67%
Ushna 33.33%
4. VIPAKA Madhura 100.00%
5. DOSHAGHNATA Tridosha Shamaka 25.00%
Vata-Pitta Shamaka 50.00%
Kapha-Vata Shamaka 25.00%

50. Action of Rasayana Yoga Ghana Vati
 Vaya Sthapana,
 Brihana,
 Balya,
 Rasayana,
 Deepan Pachana,
 Vata Shamaka
properties,
 Vrishya
 Hridya

51. RASAYANA YOGA GHANA VATI
VEHICAL
RASAYANA YOGA GHANA VATI MILK
Milk pacifies vitiated Vata and Pitta Dosas. As the milk is having identical properties
of Ojas, it promotes Ojas. The Cow’s milk acts as
Rasayana, Tarpaka, Jivaniya, Hridya, Ahladakara and Buddhi prabodhaka.

52. Importance of Anupan ( cow’s milk)
In Ayurveda, Cow’s milk is much appreciated for the therapeutic purposes and also
in preparation of the formulation as a media. The Go- dugdha possesses
properties like
Madhuram, Jivaniyam, Prinanam, Rasayanam, Brihanam, Vrishyam, Medhya, Baly
a, Dipaniya ,Shonita pittaharam, Shreshtham etc.
Chemical Composition of milk:
87.3% water
3.9% milk fat
8.8% solids- not fat
Protein – 3.25%
Lactose – 4.6%
Minerals – 0.65% - Ca, P, Mg, K, Na, Zn, CO, Fe, Cu, sulphates, bicarbonates
Acid – 0.18% - citrates, formats, acetate, lactate, oxalate.
Enzymes – peroxidase, catalase, phosphatase, lipase.
Gases – oxygen, nitrogen.
Vitamins – A, C, D, thiamine, riboflavin, others.
52

53. MODE OF ACTION OF RASAYANA YOGA
GHANA VATI
(1)According to Rasa: - Main content is Madhura rasa (38.46%) which helps to increase
dhatus, especially saumya dhatus which form the major portion of the body.
After Madhura ,Tikta rasa is the predominant one (23.07%)in present compound
formulation.Tikta rasa is having properties of Agnideepana, Pachana ,Srotoshodhana & Rasayana
prabhava in dhatu nourishment process.
Katu rasa (15.38%) by svabhava is agnideepaka, Pachaka, Srotoshodhaka &
Kaphanashaka.
(2)According to Guna:-it has got the predominance of Snigdha(26.67%).So it is Bala , Varna
vardhaka and Vajikar. After Snigdha guna ,Guru guna(20.00%) is predominant. It causes brimhana
and it is Balya & provide poshana. These guna are mainly used in pacifying the Vata prakopa &
Kapahavardhan.
(3)According to Vipaka : - It is mainly Madhura (100%) causes the expulsion of mala & mutra
from the body & releases the toxins & it is Shukral in nature.
(5)According to Veerya : - Most of the contents have Sheeta veerya (66.67%) which acts as
prahladana, Kledana & Stambhana, Balya, Prasadana & Jeevaniya .It is Kapha & Vata Shamaka.
(6) According to Doshakarma: - It works as Vata-Pitta Shamaka (50.00%) also tridosha shamaka
(25.00%).Thus it helps maintain doshic imbalance in the body & make person healthy.

55. AIM AND OBJECTIVES
1)To study the conceptual basis of ageing (jara) according to
Ayurveda and different theories of ageing according to modern
medical science.
2) To evaluate the efficacy of Rasayana yoga clinically in the
management of ageing.
3)To evaluate the role of main causes of ageing– Physical &
Mental Stress, Improper Life Style & Dietary Habits and
medication of the proper Rasayana Drugs at proper time in a
proper way.
4) To access the effect of Rasayana Dravya on different age
group clinically

56. THE PATIENTS WERE
Simple Random
MATERIAL
Methods
SELECTED FROM O.P.D. and
I.P.D. of Kayachikitsa
Department of Govt. Sampling
Ayurvedic college & hospital methods
Raipur(C.G.)

57. •The patients having sign and (1)Patients of age group below 40
symptoms mentioned as per Ayurvedic and above 70 years.
and Modern literatures. Multiple and
simple random sampling method has
(2)Patients with severe cardiac
been adopted for the selection of 60 disease, Pulmonary Tuberculosis,
uncomplicated cases. Severe hypertension and DM,
•Age incidence-The Patients between HIV, Hepatitis B etc
40 to 70 years of age. (3)Patients with malignant
•Sex- Patients of either sex were
included.
carcinoma
•Duration of illness – Not more than 3 (4)Pregnant & lactating mothers
years.
•Habitat-Both urban and rural areas
were selected.
•Religion, Occupation, Caste, Socio-
economic status-No bar.
•Patient willing to follow up regularly.

58. Having the Signs and Symptoms of Jara as described in Ayurvedic
texts.
Detailed history was taken and physical examination was done on the
basis of a special Proforma incorporating all the signs and Symptoms
of the disease.
The routine hematological and urine examination was carried out in
selected patients to exclude any other pathology as well as to assess
the present condition of the patient.

59. ASSOCIATED SYMPTOMS
1. Indigestion
2. Altered Bowel pattern
3. Altered Sleep pattern
4. Palpitation
5. Anger
6. Irritability
7. Early Menopause
8. Altered Urinary Symptoms
9. Recurrent Infections
10. Fatigue
11. Weakness
12. Loss of Hearing
13. Weakening of Teeth
59

60. HEALTH PARAMETERS
(DIAGNOSTIC CRITERIA)
(a) Walking Time
(b) Handgrip Power
(c) Foot Pressure
(d) Short Term Memory
(e) Long Term Memory
(f) Breath Holding Time
(g) Pulse, B.P., Temperature & Weight
All these vital data are recorded before & after
treatment.
As per above sign & symptoms patient examination
proforma will be prepared & patients will be selected
for trial.
60

61. CLINICAL STUDY
It will be undertaken on following parameters:-
A) Number of patients:- 60(sixty) patients will be selected for randomized clinical
trial.
B) Place of selection of patients:- Patients will be selected from the OPD & IPD of
Govt. Auto. Ayurvedic College Hospital, Raipur, Chhattisgarh
C)Criteria for selection of the patient:-
i) Patient between 40 -70 yrs age group will taken for present study.
ii) Patients will be selected on the basis of sign & symptoms available in Ayurveda
texts viz. Charak Samhita, Sushrut Samhita & Ashtang Samgraha.
61

62. GROUPINGS
“In all the three groups, Haritaki Churna – 5 gms is used during samanya
samsodhan with luke warm water for Koshtha & Srotas Shuddhi before starting the
medication”
1) Group A: 20(twenty) patients will be taken between 40 -50 yrs age group and
will be given Rasayan yoga orally.
Drug dose: 1 gm BD
Anupana: Milk
Duration: 02(Two) Months
2) Group B: 20(twenty) patients will be taken between 51 -60yrs age group and will
be given Rasayan yoga orally.
Drug dose: 1 gm BD
Anupana: Milk
Duration: 02(Two) Months
3) Group C: 20 (twenty) patients will be taken between 61-70yrs age group and will
be given Rasayan yoga orally.
Drug dose: 1 gm BD
Anupana: Milk
Duration: 02(Two) Months
62

63. Investigations
The Routine Routine & Serum of the
haematological microscopic urine patients were tested
examination of blood analysis were for HDL, LDL,
carried out to detect
like Hb% , TLC , DLC Triglyceride,
the involvement of
MCH, MCHC, MPV, Creatinine , Albumin,
kidneys and to
MCV,ESR were done. exclude the urinary Globulin, A/G Ratio,
tract infectious blood urea, Blood
conditions like Sugar (Fasting &PP)
veneral disease, ,Total protein, Total
syphilis etc. cholesterol.

64. OBSERVATIONS
Status wise distribution Age & sex wise distribution
20 19
20 17 20
7
No. of patients
15 8
No. of patients
15 11 Group C F
10 Group C M
10
3 Group B F
5 1 12 13
0 9 Group B M
5
0 Group A F
Completed LAMA
Group A M
0
Status 40-50 51-60 61-70
Age Group
Group A Group B Group C

65. Sex wise distribution Religion wise distribution
13
12 20 17
14 11 15
9 14
No. of pateints
12
No. of patients
8 15
10 7
8 10
6
4 5
33 2
2 11 0 1 1
2 0 00
0 0
Female Male Hindu Muslim Christian Sikh Other
Sex group Religion group
Group A Group B Group C Group A Group B Group C
Marital status wise distribution Education wise distribution
18 7 7
20 7 6
15
6 5 5 Group A
No. of patients
No. of patients
15 11 5 4 4 4 4
4 3 3 3 Group B
10 7 3 22
4 2 1
5 2 Group C
11 0 0 0 1 1
0
Illiterate
Graduate
PG
Primary
High.Sec.
0
Umarried Married Widow Divorce
Marital status
Education
Group A Group B Group C

66. Residence wise distribution Occupation wise distribution
15 7
13 14 7 6 66
15
No. of patients
6 5 5 5 Group A
5 4 44
No. of patients
10 7 4 3 3 Group B
5 6 3
2 11
5 1 0 0 00 Group C
0
Service
Labourer
Retired
Household
Unemployed
Buiseness
0
Rural Urban
Residence group
Group A Group B Group C
occupation
Socio-economic wise distribution
10 9
8
7
No. of patients
8
6 4 4 4 4
4
3 3 3 3 3
2 2
1
2
0
Poor Lower Middle Upper Rich
middle middle
Socio-economic status
Group A Group B Group C

67. Type of diet wise distribution
14 15
15 12
No. of patients
8
10 6
5
5
0
Vegetarian Mixed
Type of diet
Group A Group B Group C

68. Supplementary diet wise distribution Addiction wise distribution
20
19 88
20 17 8
No. of patients 7 6 6 6 66 Group A
No. of patients
15 12 6
10 10 5 4 4
10 88 88 4 3 Group B
3 5 3 2 2
5 2 1
000 1 0 0 Group C
0 0
Smoking
Alcohol
Tobbaco
Sedatives
Panmasala
Tea Coffe Cold Milk Other
chew
drink
Supplementary diet group
Group A Group B Group C
Addiction
Dominant Rasa of Ahara wise distribution
2018
20 18 18 18
17 16 16
15 14
No. of patients
15 12 12
10
6
5
3 3
5 2 3
0
Madhra Amla Lavana Katu Tikta Kashaya
Type of Aha ra Rasa
Group A Group B Group C

69. Dominant Guna of Ahara wise distribution
14
14 13 13 1313
12 12 12 12 12 12
No. of patients
12 10 11
10 9
10 88 8
8
6
4
2
0
Guru Laghu Sheeta Ushna Snigdha Ruksha
Type of Ahara Guna
Group A Group B Group C
Ayogya Ahara Vidhi wise distribution
20 Anushna
18
16 Asnigdha
No. of patients
14
Amatravata
12
10 Ajirne
8
6 Viryaviruddha
4
2 Anishtadesha
0
Group A Group B Group C Anishta
upakarana
Types of Ayogya ahara vidhi Anmanaska
Atmanam

70. Diet habit wise distribution Kostha wise distribution
16
11
12 16
13
10
9 8 8 8 14
No. of patients
7
No.f patients
7 6 12
8 6 9
10
6 8
6
5 4
4 6
3 2 2
4
2 2
0 0
Samashana Vishmashana Adhyashana Mridu Madhyam Krura
Diet habit Type of Kostha
Group A Group B Group C
Group A Group B Group C
Exercise wise distribution
14 13
12 Group
No. of patients
10 A
88
8 6 Group
6 5
4 4 B
4 3 2
2 1 11 11 1 0
Group
0 0 C
0
Ir lar
E er
R se
ex lar
s
se
P s
es
s
p
o u
i
u
ci
Le
rc
ro
N eg
eg
xc
er
xe
r
E
Exercise group

71. Nidra wise distribution Dincharya Palana wise distribution
18 18 16
18 17 15
15 14
16 16
13 13 13 14
14 Group
No. of patients
No. of patients
12
12 11 10 A 12
10
10 9 10 9 Group 10
7
B
8 6
8 4 5
6 5 5
Group 6
C
3
4
4 2 22
2
2
0
0 Samyaka Asamyaka
na
As aka
ka
a s ta
pa
na
a
ut
i
ap
ya
nd
Al
ra Dincharya group
bh
y
ag
m
am
w
a
a
Kh
Sa
Pr
rij
iw
at
D
R
Group A Group B Group C
Nidra group
Ratricharya wise distribution
14
14 12 11
12
No. of pateints
9 8
10
6
8
6
4
2
0
Sa mya ka Asa mya ka
Ra tricha rya group
Group A Group B Group C

72. Ritucharya Palana wise distribution Sadvritta Palana wise distribution
16
17 16 16
16 13 20
14 11
No. of patients
No. of patients
12 15
9
10 7
8 10
4 4
6 4
5
3
4
2
0 0
Samyaka Asamyaka Samyaka Asamyaka
Ritucharya group Sadvritta group
Group A Group B Group C Group A Group B Group C
Sha ririka pra kriti w ise distribution
15
16
14 12 Group A
No. of patients
12
9
10
8 7 Group B
6 4 4 4 4
4
1 Group C
2 0 0 0 00 0
0
ap haj
j
aj
j
j
ha
ha
a
itt
at
p
os
os
P
V
a
K
kd
aj
rid
ha
a
at
E
T
itt
V
P
K
Sha ririka pra kriti

73. Manasika Prakriti wise distribution
12 Sara wise distribution
13
12 10 14
9 11
No. of patients 10 8 7 12
9
No. of patients
8 6 10 8
6 4 8 5
4 2 2 6 4 3 4
3
2 4
0 2
Rajasika Tamsika Rajasika- 0
Tamsika Pravara Madhyama Avara
Manasika prakriti
Type of Sara
Group A Group B Group C
Group A Group B Group C
Satva wise distribution 14 Samhanana wise distribution
13 12 11
14 10
12 10 10
No. of patients
8
No. of patients
10 7 7
8 6
8 6
5 5
4 4
6
6 3 3
2 2 4
4
2 2
0 0
Pravara Madhyama Avara Pravara Madhyama Avara
Type of satva Type of samhanana
Group A Group B Group C Group A Group B Group C

74. Pramana wise distribution Satmya wise distribution
13
14 12 12
11
No. of patients 12 12 10 10
10 10
No. of patients
8
5 8 6 7 7
6 4 4 5
4 3 3 6
4
3 3
2 2
0 2
Pravara Madhyama Avara 0
Type of pramana Pravara Madhyama Avara
Group A Group B Group C Group A Type of satmya
Group B Group C
Vyayamshakti wise distribution
15
16
14
No. of patients
12 10
9
10
7
8 5 5
6 4 4
4 1
2
0
Pra va ra Ma dhya ma Ava ra
Vya ya msha kti
Group A Group B Group C

75. Agni wise distribution
14
14 13
12 10 Abhyavarana shakti wise distribution
No. of patients
10
8 6
6 5
4
10 10
4 2 2 10 9
11 1 1
2
7
No. of patients
0
Mandagni Tikshnagni Vishmagni Samagni 8 6 6
Type of agni
Group A Group B Group C 6 5
4
4
3
Jarana shakti wise distribution 2
10
10 8 0
7 7 7 7 Pravara Madhyam Avara
No. of patients
8 6
5
6
3
Abhyavarana shakti
4
2 Group A Group B Group C
0
Pravara Madhyam Avara
Jarana Shakti
Group A Group B Group C

77. Percentage
95.00% 53.33% 90.00%
88.33%
98.33% 80.00%
70.00% 43.33%
90.00% 81.66%
80.00% 51.66%
86.66%
Indigetion Constipation
Disturbed sleep Palpitation
Anger Irritability
Loss of hearing W eakning of teeth
Early menopause Recurrent infection
Fatigue W eakness
Altered urinary symptoms

78. Dhatu Kshaya wise distribution
20 20 20 20
19 19 19
20
18 18
18 17 16 17
16 16 16
16 14 14 Group A
13
14
No. of patients
12
10 Group B
7
8 6
6 4
Group C
4
2
Ojodushti wise distribution
0
i
sa
a
sa
a
a
th
ja
kt
kr
ed
17
aj
a
s
am
20
a
u
R
A
M
M
R
h
M
S
14
No. of patients
Dhatu
15 11
9 9
10 7 7 7
4
5
0
Vyapada Visramsa Kshaya
Type of ojodushti
Group A Group B Group C

79. SHOWING PERCENTAGE OF IMPROVEMENT IN VARIOUS SIGN AND SYMPTOMS AFTER TWO
MONTH OF TREATMENT IN 20 PATIENT OF JARA ROGA OF “GROUP A”
S. No. Sign & Symptoms Before Treatment After Treatment
G0 G1 G2 G3 Total G 0 G 1 G 2 G 3 Total % OF
RELIEF
1. Twak Parushata 6 5 6 3 26 15 3 2 0 7 73.08%
2. Slatha sara 0 4 8 8 44 14 3 2 1 10 77.27%
3. Slatha mamsa 2 3 8 7 40 14 2 2 2 13 67.50%
4. Slatha Asthi 2 8 5 5 33 14 2 1 3 13 60.60%
5. Slatha Sandhi 4 7 6 3 28 14 4 1 1 9 67.86%
6. Dhatu Kshaya 0 12 4 4 32 14 4 2 0 8 75.00%
7. Kayasya
19 1 0 0 1 20 0 0 0 0 100.00%
Avanamana
8. Vepthu 15 3 1 1 8 18 2 0 0 2 75.00%
9. Khalitya 0 7 8 5 38 13 2 4 1 13 65.79%
10. Vali 2 10 5 3 29 13 3 2 2 13 55.17%
11. Palitya 2 9 7 2 29 14 2 3 1 11 62.07%

80. 12. Kasa 06 7 6 1 22 14 4 2 0 8 63.64%
13. Shwasa 13 5 2 0 9 18 1 1 0 3 66.67%
14. MEDHA HANI
i. Grahana hahi 1 15 3 1 24 14 4 1 1 9 62.50%
ii. Dharana hani 1 16 2 1 23 15 4 1 0 06 73.91%
iii. Smarana hani 0 7 10 3 36 13 3 3 1 12 66.67%
iv. Vijnana hani 13 3 4 0 11 17 2 1 0 4 63.64%
v. Vachana hani 0 0 0 0 0 0 0 0 0 0 00.00%
15. Utsaha hani 6 5 5 4 27 15 2 1 2 10 62.96%
16. Parakrama hani 2 7 6 5 34 13 1 4 2 15 55.88%
17. Paurusha hani 19 1 0 0 1 20 0 0 0 0 100%
18. Prabaha hani 3 13 3 1 22 15 2 2 1 9 59.09%
19. Shukra Kshaya 15 3 2 0 7 16 2 2 0 6 14.28%
20. Drishti Hrasa 4 12 4 0 20 6 12 2 0 16 20.00%
21. Karmendriya hani 10 6 4 0 14 17 2 1 0 4 71.42%
22. Buddhi hani 15 4 1 0 6 18 1 1 0 3 50.00%

81. SHOWING PERCENTAGE OF IMPROVEMENT IN VARIOUS SIGN AND SYMPTOMS AFTER TWO
MONTH OF TREATMENT IN 19 PATIENT OF JARA ROGA OF “GROUP B”
S. Sign & Symptoms Before Treatment After Treatment
No. G0 G1 G2 G3 Total G 0 G 1 G 2 G 3 Total % OF
RELIEF
1. Twak Parushata 2 7 6 4 31 10 7 2 0 11 64.52%
2. Slatha sara 0 5 10 4 37 10 7 1 1 12 67.57%
3. Slatha mamsa 2 3 9 5 36 11 5 2 1 12 66.67%
4. Slatha Asthi 1 7 8 3 32 11 6 2 0 10 68.75%
5. Slatha Sandhi 0 6 8 5 37 12 4 1 2 12 67.56%
6. Dhatu Kshaya 0 4 11 4 38 10 4 3 2 16 57.89%
7. Kayasya
13 3 2 1 10 15 3 1 0 5 50.00%
Avanamana
8. Vepthu 11 3 3 2 15 14 3 1 1 8 46.67%
9. Khalitya 0 6 11 2 34 1 8 8 2 30 11.76%
10. Vali 0 3 13 3 38 0 7 10 2 33 13.16%
11. Palitya 0 6 12 1 33 4 4 10 1 27 18.18%

82. 12. Kasa 2 4 9 4 34 11 4 4 0 12 64.71%
13. Shwasa 5 5 6 3 26 13 4 2 0 8 69.23%
14. MEDHA HANI
i. Grahana hahi 0 9 5 5 34 10 3 4 2 17 50.00%
ii. Dharana hani 0 12 4 3 29 11 5 2 1 12 58.62%
iii. Smarana hani 0 10 7 2 30 10 6 2 1 13 50.00%
iv. Vijnana hani 13 2 3 1 11 16 1 1 1 6 45.45%
v. Vachana hani 18 1 0 0 1 18 1 0 0 1 00.00%
15. Utsaha hani 2 9 6 2 27 11 4 3 1 13 51.85%
16. Parakrama hani 0 8 7 4 34 10 2 5 2 18 47.06%
17. Paurusha hani 14 3 1 1 8 16 2 1 0 4 50.00%
18. Prabaha hani 1 13 3 2 25 7 9 2 1 16 36.00%
19. Shukra Kshaya 13 3 2 1 10 14 3 1 1 8 20.00%
20. Drishti Hrasa 2 9 8 0 25 3 8 8 0 24 4.00%
21. Karmendriya hani 9 5 3 2 17 15 2 1 1 7 58.82%
22. Buddhi hani 11 5 3 0 11 14 5 0 0 5 54.55%

83. SHOWING PERCENTAGE OF IMPROVEMENT IN VARIOUS SIGN AND SYMPTOMS AFTER TWO
MONTH OF TREATMENT IN 17 PATIENT OF JARA ROGA OF “GROUP C”
S.No. Sign & Symptoms Before Treatment After Treatment
G0 G1 G2 G3 Total G 0 G 1 G 2 G 3 Total % OF
RELIEF
1. Twak Parushata 0 3 10 4 35 2 5 7 3 28 20.00%
2. Slatha sara 0 0 9 8 42 4 9 2 2 19 54.76%
3. Slatha mamsa 0 2 10 5 37 8 2 6 1 17 54.05%
4. Slatha Asthi 1 4 7 5 33 6 6 3 2 18 45.45%
5. Slatha Sandhi 0 3 8 6 37 5 10 1 1 15 59.46%
6. Dhatu Kshaya 0 0 10 7 41 2 5 6 4 29 29.27%
7. Kayasya Avanamana 13 1 2 1 8 13 1 2 1 8 00.00%
8. Vepthu 11 4 2 0 8 13 3 1 0 5 37.50%
9. Khalitya 0 3 6 8 39 0 3 8 6 37 05.13%
10. Vali 0 2 11 4 36 0 5 8 4 33 08.33%
11. Palitya 0 0 7 10 44 0 0 7 10 44 00.00%
12. Kasa 2 3 7 5 32 8 6 1 2 14 56.25%

84. 13. Shwasa 5 3 8 1 22 11 2 3 1 11 50.00%
14. MEDHA HANI
i. Grahana hahi 0 5 10 2 31 6 9 2 0 13 58.06%
ii. Dharana hani 0 4 12 1 31 7 8 2 0 12 61.29%
iii. Smarana hani 0 6 8 3 31 1 9 6 1 24 22.58%
iv. Vijnana hani 3 5 8 1 24 5 8 3 1 17 29.17%
v. Vachana hani 15 1 1 0 3 15 1 1 0 3 00.00%
15. Utsaha hani 0 4 12 1 31 11 4 2 0 8 74.19%
16. Parakrama hani 0 2 13 2 34 10 5 2 0 9 73.53%
17. Paurusha hani 9 5 2 1 12 13 1 2 1 8 33.33%
18. Prabaha hani 0 6 9 2 30 2 8 5 2 24 20.00%
19. Shukra Kshaya 11 3 1 2 11 11 4 1 5 9 18.18%
20. Drishti Hrasa 0 2 10 5 37 0 2 10 1 37 00.00%
21. Karmendriya hani 3 3 7 4 29 11 6 0 0 6 79.00%
22. Buddhi hani
6 5 2 1 12 11 4 1 1 9 25.00%

86. Statistical Analysis Showing the Effect of Trial Drug to the Sign & Symptoms of the Patients (20) of Group ‘A’
S. Sign & Symptoms B.T. A. T. D % of Relief S. D. S. E. T-value P value Remarks
Mean Mean (Paired test)
No.
1. Twak Parushata 1.30 0.35 0.95 73.08% 0.83 0.19 5.15 <0.001 H.S.
2. Slatha sara 2.20 0.50 1.70 77.27% 1.03 0.23 7.37 <0.001 H.S.
3. Slatha mamsa 2.00 0.65 1.35 67.50% 1.09 0.24 5.54 <0.001 H.S.
4. Slatha Asthi 1.65 0.65 1.00 60.60% 0.79 0.18 5.63 <0.001 H.S.
5. Slatha Sandhi 1.40 0.45 0.95 67.86% 0.89 0.19 4.79 <0.001 H.S.
6. Dhatu Kshaya 1.60 0.40 1.20 75.00% 0.70 0.16 7.71 <0.001 H.S.
7. KayasyaAvanamana 0.05 0.00 0.05 100.00% 0.22 0.05 1.00 >0.05 N.S.
8. Vepthu 0.40 0.10 0.30 75.00% 0.57 0.13 2.35 <0.05 Sig.
9. Khalitya 1.90 0.65 1.25 65.79% 0.85 0.19 6.57 <0.001 H.S.
10 Vali 1.45 0.65 0.80 55.17% 0.69 0.16 5.14 <0.001 H.S.
11. Palitya 1.45 0.55 0.90 62.07% 0.64 0.14 6.28 <0.001 H.S.
12. Kasa 1.10 0.40 0.70 63.64% 0.57 0.13 5.48 <0.001 H.S.
13. Shwasa 0.15 0.30 0.47 0.11 2.85 <0.01 H.S.
0.45 66.67%
14. MEDHA HANI
i. Grahana hahi 0.45 0.75 62.50% 0.55 0.12 6.09 <0.001 H.S.
1.20

87. ii. Dharana hani 1.15 0.30 0.85 0.49 0.11 7.77 <0.001 H.S.
73.91%
iii. Smarana hani 1.80 0.60 1.20 0.77 0.17 6.99 <0.001 H.S.
66.67%
iv. Vijnana hani 0.55 0.20 0.35 0.59 0.13 2.66 <0.02 Sig.
63.64%
v. Vachana hani 0.00 0.00 0.00 0.00 0.00 0.00 >0.05 N.S.
00.00%
15. Utsaha hani 1.35 0.50 0.85 0.88 0.19 4.34 <0.001 H.S.
62.96%
16. Parakrama 1.70 0.65 1.05 0.99 0.22 4.70 <0.001 H.S.
55.88%
hani
17. Paurusha hani 0.05 0.00 0.05 100.00% 0.22 0.05 1.00 >0.05 N.S.
18. Prabaha hani 1.10 0.45 0.65 0.59 0.13 4.95 <0.001 H.S.
59.09%
19. Shukra Kshaya 0.35 0.30 0.05 14.28% 0.22 0.05 1.00 >0.05 N.S.
20. Drishti Hrasa 1.00 0.80 0.20 0.52 0.12 1.71 >0.05 N.S.
20.00%
21. Karmendriya 0.70 0.20 0.50 0.68 0.15 3.25 <0.01 H.S.
hani 71.42%
22. Buddhi hani 0.30 0.15 0.15 0.36 0.08 1.83 >0.05 N.S.
50.00%

88. Statistical Analysis Showing the Effect of Trial Drug to the Sign & Symptoms of the Patients (19) of Group „B‟
S. Sign & Symptoms B.T. A. T. D % of S. D. S. E. T-value P value Remark
No. Mean Mean Relief (Paired s
test)
1. Twak Parushata 1.63 0.58 1.05 64.52% 0.78 0.18 5.88 <0.001 H.S.
2. Slatha sara 1.95 0.63 1.32 67.57% 0.82 0.19 6.99 <0.001 H.S.
3. Slatha mamsa 1.89 0.68 1.21 63.89% 0.71 0.16 7.39 <0.001 H.S.
4. Slatha Asthi 1.68 0.63 1.05 62.50% 0.52 0.12 8.75 <0.001 H.S.
5. Slatha Sandhi 1.95 0.68 1.26 64.86% 0.73 0.16 7.51 <0.001 H.S.
6. Dhatu Kshaya 1.79 0.84 0.95 57.89% 0.91 0.20 4.53 <0.001 H.S.
7. Kayasya Avanamana 0.53 0.26 0.26 50.00% 0.56 0.13 2.04 >0.05 N.S.
8. Vepthu 0.79 0.42 0.37 46.67% 0.68 0.16 2.35 <0.05 Sig.
9. Khalitya 0.58 0.32 0.26 45.45% 0.56 0.13 2.04 >0.05 N.S.
10 Vali 2.00 1.84 0.16 13.15% 0.37 0.09 1.84 >0.05 N.S.
11. Palitya 2.20 1.59 0.61 18.18% 0.37 0.09 1.84 >0.05 N.S.
12. Kasa 1.79 0.63 1.16 64.71% 0.60 0.14 8.38 <0.001 H.S.
13. Shwasa 1.37 0.42 0.95 69.23% 0.85 0.19 4.869 <0.001 H.S.
14. MEDHA HANI
i. Grahana hahi 1.79 0.89 0.89 50.00% 0.57 0.13 6.88 <0.001 H.S.

89. ii. Dharana hani 1.53 0.63 0.89 0.46 0.11 8.50 <0.001 H.S.
58.62%
iii. Smarana hani 1.58 0.68 0.89 0.74 0.17 5.28 <0.001 H.S.
50.00%
iv. Vijnana hani 0.58 0.32 0.26 0.56 0.13 2.04 >0.05 N.S.
45.45%
v. Vachana hani 0.05 0.05 0.00 _ _ _ _ _
00.00%
15. Utsaha hani 1.42 0.68 0.74 0.65 0.15 4.91 <0.001 H.S.
51.85%
16. Parakrama hani 1.79 0.95 0.84 47.06% 0.77 0.18 4.80 <0.001 H.S.
17. Paurusha hani 0.42 0.21 0.21 0.42 0.10 2.19 <0.05 Sig.
50.00%
18. Prabaha hani 1.32 0.84 0.47 0.77 0.18 2.67 <0.02 Sig.
36.00%
19. Shukra Kshaya 0.53 0.42 0.11 0.32 0.07 1.45 >0.05 N.S.
20.00%
20. Drishti Hrasa 1.32 1.26 0.05 0.23 0.05 1.00 >0.05 N.S.
4.00%
21. Karmendriya 0.89 0.37 0.53 0.69 0.16 3.29 <0.01 H.S.
hani 58.82%
22. Buddhi hani 0.58 0.26 0.32 0.48 0.11 2.88 0.01 H.S.
54.55%

90. Statistical Analysis Showing the Effect of Trial Drug to the Sign & Symptoms of the Patients (17) of Group „C‟
S. Sign & Symptoms B.T. A. T. D % of S. D. S. E. T-value P value Remarks
No. Mean Mean Relief
1. Twak Parushata 2.05 1.64 0.41 20.00% 0.71 0.17 2.38 <0.05 Sig.
2. Slatha sara 2.53 1.12 1.41 54.76% 0.79 0.19 7.32 <0.001 H.S.
3. Slatha mamsa 2.18 1.00 1.17 54.05% 0.73 0.18 6.67 <0.001 H.S.
4. Slatha Asthi 1.94 1.05 0.88 45.45% 0.78 0.19 4.66 <0.001 H.S.
5. Slatha Sandhi 2.18 0.88 1.29 59.46% 0.68 0.17 7.78 <0.001 H.S.
6. Dhatu Kshaya 2.41 1.70 0.70 29.27% 0.84 0.20 3.43 <0.01 H.S.
7. Kayasya Avanamana 0.47 0.47 0.00 00.00% _ _ _ _ N.S.
8. Vepthu 0.47 0.29 0.18 37.50% 0.39 0.09 1.85 >0.05 N.S.
9. Khalitya 2.29 2.11 0.18 05.13% 0.39 0.09 1.85 >0.05 N.S.
10 Vali 2.12 1.94 0.18 08.33% 0.39 0.09 1.85 >0.05 N.S.
11. Palitya 2.58 2.58 0.00 00.00% _ _ _ _ N.S.
12. Kasa 1.88 0.82 1.06 56.25% 0.75 0.18 5.84 <0.001 H.S.
13. Shwasa 1.29 0.65 0.65 50.00% 0.79 0.19 3.39 <0.01 H.S.
14. MEDHA HANI

91. i. Grahana hahi 1.82 0.77 0.11 58.06% 0.827 0.20 5.28 <0.001 H.S.
ii. Dharana hani 1.82 0.71 1.12 61.29% 0.857 0.21 5.37 <0.001 H.S.
iii. Smarana hani 1.82 1.41 0.41 22.58% 0.62 0.15 2.75 <0.02 Sig.
iv. Vijnana hani 1.41 1.24 0.18 29.17% 0.53 0.13 1.38 >0.05 N.S.
v. Vachana hani 1.77 1.77 0.00 00.00% _ _ _ _ N.S.
15. Utsaha hani 1.59 0.53 1.06 74.19% 0.899 0.22 4.85 <0.001 H.S.
16. Parakrama hani 1.88 0.59 1.29 73.53% 0.849 0.21 6.29 <0.001 H.S.
17. Paurusha hani 0.71 0.59 0.12 33.33% 0.33 0.08 1.46 >0.05 N.S.
18. Prabaha hani 1.76 1.41 0.35 20.00% 0.606 0.15 2.40 <0.05 Sig.
19. Shukra Kshaya 0.65 0.53 0.11 18.18% 0.332 0.08 1.46 >0.05 N.S.
20. Drishti Hrasa 2.17 2.18 0.00 00.00% _ _ _ _ N.S.
21. Karmendriya 1.76 1.41 0.35 0.606 0.15 2.40 <0.05 Sig.
20.00%
hani
22. Buddhi hani 0.65 0.53 0.11 18.18% 0.332 0.08 1.46 >0.05 N.S.

93. Statistical Analysis Showing the Effect of Trial Drug to the Associated Sign & Symptoms -Patients (20) of Group „A‟
S. No. Associated sign Mean Score D % of S. D. S. E. T-value P value Remar
&Symptoms Relief (Paired test) ks
B.T. A. T.
1. Indigestion 1.15 0.30 0.85 73.91% 1.14 0.25 3.34 <0.01 H.S.
2. Constipation 1.45 0.25 1.20 82.75% 0.70 0.16 7.71 <0.001 H.S.
3. Disturbed sleep 1.20 0.30 0.90 75.00% 0.64 0.14 6.28 <0.001 H.S.
4. Palpitation 0.50 0.15 0.35 70.00% 0.59 0.13 2.66 <0.02 Sig.
5. Anger 1.30 0.50 0.80 61.54% 0.69 0.16 5.14 <0.001 H.S.
6. Irritability 1.25 0.50 0.75 60.00% 0.44 0.09 7.55 <0.001 H.S.
7. Loss of Hearing 1.26 1.16 0.11 08.73% 0.32 0.07 1.46 >0.05 N.S.
8. Weakening of teeth 0.90 0.75 0.15 16.67% 0.49 0.11 1.37 >0.05 N.S.
9. Early menopause 1.15 0.40 0.75 78.26% 0.78 0.18 4.27 <0.001 H.S.
10 Recurrent infection 0.85 0.40 0.45 70.59% 0.61 0.14 3.31 <0.01 H.S.
11. Fatigue 1.65 0.20 1.45 87.88% 0.61 0.14 10.72 <0.001 H.S.
12. Weakness 1.30 0.15 1.15 88.46% 0.59 0.13 8.76 <0.001 H.S.
13. Altered urinary 0.45 0.20 0.25 55.56% 0.44 0.09 2.52 0.02 Sig.
symptoms

94. Statistical Analysis Showing the Effect of Trial Drug to the Sign & Symptoms of the Patients (19) of Group „B‟
S. No. Associated sign B.T. A. T. D % of S. D. S. E. T-value P value Remarks
&Symptoms Mean Mean Relief (Paired test)
1. Indigestion 1.74 0.89 0.84 48.27% 0.69 0.16 5.33 <0.001 H.S.
2. Constipation 1.47 0.63 0.84 57.14% 0.76 0.17 4.80 <0.001 H.S.
3. Disturbed sleep 1.47 0.84 0.63 42.86% 0.89 0.21 3.08 <0.01 H.S.
4. Palpitation 0.53 0.32 0.21 39.62% 0.54 0.12 1.70 >0.05 N.S.
5. Anger 1.63 0.89 0.74 45.39% 0.99 0.23 3.24 <0.01 H.S.
6. Irritability 1.63 1.26 0.37 22.70% 0.49 0.11 3.24 <0.01 H.S.
7. Loss of Hearing 0.53 0.53 0.00 0.00% - - - - N.S.
8. Weakening of teeth 1.26 1.16 0.11 08.73% 0.32 0.07 1.46 >0.05 N.S.
9. Early menopause 1.73 1.47 0.26 15.03% 0.45 0.10 2.54 0.02 Sig.
10 Recurrent infection 1.16 0.42 0.74 63.79% 0.73 0.17 4.38 <0.001 H.S.
11. Fatigue 1.74 0.15 1.57 90.00% 0.84 0.19 8.21 <0.001 H.S.
12. Weakness 1.36 0.37 1.00 73.53% 0.47 0.11 9.25 <0.001 H.S.
13. Altered urinary 1.00 0.47 0.53 53.00% 0.84 0.19 2.72 <0.02 Sig.
symptoms

95. Statistical Analysis Showing the Effect of Trial Drug to the Sign & Symptoms of the Patients (17) of Group „C‟
S. No. Associated sign B.T. A. T. D % of S. D. S. E. T-value P value Remarks
&Symptoms Mean Mean Relief (Paired test
1. Indigestion 1.94 1.35 0.59 30.41% 0.71 0.17 3.41 <0.01 H.S.
2. Constipation 2.00 0.94 1.06 53.00% 1.29 0.31 3.36 <0.01 H.S.
3. Disturbed sleep 1.82 1.23 0.59 32.42% 0.94 0.23 2.58 0.02 Sig.
4. Palpitation 1.12 0.94 0.18 16.07% 0.39 0.10 1.85 >0.05 N.S.
5. Anger 1.47 1.00 0.47 31.97% 0.62 0.15 3.12 <0.01 H.S.
6. Irritability 1.71 1.17 0.53 30.99% 0.72 0.17 3.04 <0.01 H.S.
7. Loss of Hearing 1.41 1.41 0.00 00.00% - - - - N.S.
8. Weakening of teeth 1.76 1.76 0.00 00.00% - - - - N.S.
9. Early menopause 1.76 1.52 0.24 13.64% 0.56 0.14 1.73 >0.05 N.S.
10 Recurrent infection 1.53 0.88 0.65 42.48% 0.61 0.15 4.40 <0.001 H.S.
11. Fatigue 2.06 0.88 1.18 57.28% 0.81 0.19 5.99 <0.001 H.S.
12. Weakness 2.24 1.00 1.24 55.36% 0.83 0.20 6.13 <0.001 H.S.
13. Altered urinary 1.18 0.71 0.47 39.83% 0.52 0.13 3.77 <0.01 H.S.
symptoms

97. Statistical Analysis Showing the Effect of Trial Drug to the Health parameters of the Patients (20) of Group „A‟
S. No. Health parameters B.T. A. T. D % of S. D. S. E. T-value P value Remarks
Mean Mean Relief (Paired test
1. Walking time 1.30 0.30 1.00 73.08% 0.73 0.16 6.164 <0.001 H.S.
2. Hand Grip Power 87.17 101.60 14.43 16.55% 2.78 1.60 7.15 <0.001 H.S.
(mm hg)
3. Foot Pressure(Kg) 28.71 30.28 1.57 05.46% 1.29 0.49 3.21 <0.01 H.S.
4. Short term memory 1.26 0.37 0.89 70.63% 0.81 0.19 4.82 <0.001 H.S.
5. Long term Memory 1.25 1.00 0.25 20.00% 0.44 0.10 2.52 0.02 Sig.
6. Breath holding 28.16 30.16 2.00 07.10% 0.63 0.26 7.75 <0.001 H.S.
time(sec)
7. Pulse (min) 77.12 73.62 3.50 04.75% 1.94 1.68 5.11 <0.001 H.S.
8. Blood pressure
i. Systolic 130.64 126.8 3.84 05.29% 0.50 0.25 3.00 <0.01 H.S.
ii. Diastolic 86.45 84.26 2.19 03.34% 0.78 0.26 4.26 <0.001 H.S.
9. Weight(Kg) 56.37 57.45 1.08 01.74% 1.27 0.43 3.79 <0.01 H.S.

98. Statistical Analysis Showing the Effect of Trial Drug to the Health parameters of the Patients (19) of Group „B‟
S. No. Health parameters B.T. A. T. D % of S. D. S. E. T-value P value Remarks
Mean Mean Relief (Paired test
1. Walking time 1.58 0.58 1.00 66.67% 0.75 0.17 5.85 <0.001 H.S.
2. Hand Grip Power 82.00 94.00 12.00 14.63% 4.00 1.79 6.71 <0.001 H.S.
(mm hg)
3. Foot Pressure(Kg) 27.62 29.0 1.38 04.72% 1.11 0.39 3.50 <0.01 H.S.
4. Short term memory 1.45 0.95 0.50 34.48% 0.69 0.15 3.25 <0.01 H.S.
5. Long term Memory 2.05 1.64 0.41 39.05% 0.71 0.17 2.38 <0.05 Sig.
6. Breath holding 25.17 28.12 2.95 09.77% 0.83 0.29 9.38 <0.001 H.S.
time(sec)
7. Pulse (min.) 79.12 77.82 1.30 04.75% 1.94 1.68 5.11 <0.001 H.S.
8. Blood pressure
i. Systolic 132.28 128.2 4.08 03.34% 0.78 0.26 4.26 <0.001 H.S.
ii. Diastolic 84.25 82.56 1.69 15.06% 1.05 0.37 3.02 <0.01 H.S.
9. Weight(Kg) 53.37 55 1.63 02.94% 1.22 0.43 3.77 <0.01 H.S.

99. Statistical Analysis Showing the Effect of Trial Drug to the Health parameters of the Patients (17) of Group „C‟
S. No. Health parameters B.T. A. T. D % of S. D. S. E. T-value P value Remarks
Mean Mean Relief (Paired test
1. Walking time 2.35 2.11 0.24 10.21% 0.43 0.11 2.22 >0.05 H.S.
2. Hand Grip Power 76.50 89.83 13.33 17.42% 6.95 2.84 4.70 <0.001 H.S.
(mm hg)
3. Foot Pressure(Kg) 22 24.5 2.50 11.36% 3.73 1.52 1.64 >0.05 N.S.
4. Short term memory 1.75 1.50 0.25 14.29% 0.44 0.09 2.52 <0.05 Sig.
5. Long term Memory 2.25 2.05 0.20 08.89% 0.41 0.09 2.18 <0.05 Sig.
6. Breath holding 19.71 22.42 2.71 12.08% 2.0 0.75 3.97 <0.01 H.S.
time(sec)
7. Pulse (min.) 81.50 78.33 3.17 03.89% 3.37 1.38 2.30 <0.05 Sig.
8. Blood pressure
i. Systolic 141.50 139.75 1.75 01.24% 2.71 0.96 2.35 <0.05 Sig.
ii. Diastolic 94.00 92.86 1.14 01.21% 1.07 0.40 2.83 <0.02 Sig.
9. Weight(Kg) 51.71 53.14 1.43 02.74% 0.90 0.34 4.18 <0.001 H.S.

100. OVER ALL EFFECT OF THERAPY
% OF RELIEF EFFECT
MORE THAN 76% Maximum Improvement
51-75 % Moderate Improvement
26-50% Mild Improvement
LESS THAN 25% No Improvement
11/27/2011

101. OVER ALL EFFECT OF THE THERAPY ON GROUP „A‟ ,GROUP „B‟ AND GROUP „C‟ PATIENTS OF JARA ROGA
RESULT Group A Group B Group C Total
No. of % No. of % No. of % No. of %
pts. Pts. Pts. pts.
Maximum 06 30.00% 04 21.05% 02 11.76% 12 21.43%
improvement
76 % or more
Moderate 08 40.00% 05 26.31% 03 17.65% 16 28.57%
improvement
51%&75%
Mild 03 15.00% 06 31.57% 06 35.29% 15 26.79%
improvement
26%&50%
No 03 15.00% 04 21.05% 06 35.29% 13 23.21%
improvement
25% or less
Total 20 100% 19 100% 17 100% 56 100%

102. GRAPHICAL REPRESENTATION OF THE COMPARATIVE TOTAL EFFECT
OF THERAPY ON THE PATIENTS OF JARA ROGA OF GROUP „A‟
GROUP „A‟
Total effect of therapy on 20 Patients of Jara Roga Of Group A
40%
30% 15%
15%
Maximum improvement Moderate improvement Mild improvement Unchanged

103. GRAPHICAL REPRESENTATION OF THE COMPARATIVE TOTAL EFFECT OF
THERAPY ON THE PATIENTS OF JARA ROGA OF GROUP „B‟
GROUP „B‟
Total effect of therapy on 19 Patients of Jara Roga Of Group B
26%
32%
21%
21%
Maximum improvement Moderate improvement Mild improvement Unchanged

104. GRAPHICAL REPRESENTATION OF THE COMPARATIVE TOTAL EFFECT OF
THERAPY ON THE PATIENTS OF JARA ROGA OF GROUP „C‟
GROUP „C‟
Total effect of therapy on 17 Patients of Jara Roga Of Group C
35%
18%
35%
12%
Maximum improvement Moderate improvement Mild improvement Unchanged

105. GRAPHICAL REPRESENTATION OF THE COMPARATIVE
TOTAL EFFECT OF THERAPY ON THE PATIENTS
OF JARA ROGA OF
GROUP „A‟, GROUP „B‟AND GROUP „C‟
40 40 35.29 35.29
35 30 31.57
30 26.31 Group A
25 21.05 21.05
Group B
Percent
17.65 15 15
20
11.76 Group C
15
10
5
0
Maximum Moderate Mild Unchanged
improvement improvement improvement

106. The thesis entitled "A Clinical study on the
concept of Jara w.s.r. to ageing process
and its management by Rasayana yoga.”
Consists of seven sections namely
The Conceptual Contrive
Concept of Rasayana
Drug Contrive
Clinical Contrive
Discussion
Summary and Conclusion
Addenda

107. CONCEPTUAL STUDY :-
•Akalaja Jara can be treated effectively.
•Kala, Swabhava, Vayu and Virodhaka Bhava play a major
role while Desha, Ahara Sausthavam (Dietary Habits),
Lifestyle and Avighata (disturbed Manasika Bhava-Stress)
contribute to the Ageing Process .
•In the present stressful environment, disturbed Manasika
Bhava like Shoka, Chinta, Bhaya etc. are observed to be
playing a vital role in the etiopathogenesis Premature
Ageing.
•Stress induced free radicals being highly reactive and
unstable damage the cell membrane and cytosol and if
unchecked, hastens the process of Ageing.

108. •Antioxidants counteract the free radicals by inhibiting the generation of
ROS or by directly scavenging or by raising endogenous antioxidant
defenses.
•Rasayana is being practiced effectively and extensively since ages. It has
preventive, promotive and curative aspects, hence, best rejuvenator of
the body.
•Maximum benefits of Rasayana can be yielded in Purva Vayas or Madhya
Vayas.
•Rasayana have the properties similar to Adaptogens, Antioxidants,
Immunostimulants, Nootropics, Anabolics, Tonics and other Geriatric
remedies.
•The selected drug Rasayana Yoga Ghana Vati is having the best
properties of Rasayana with specific property of Dhatupushtikar
(Rejuvenator) type of Rasayana, which can slow down the Ageing
Process by treating the main symptom Dhatukshaya and it is also Balya.

109. CLINICAL STUDY :-
•Improper food habit & life style and Disturbed Manasika Bhava – stress
are the main causative factors of Premature Ageing.
•Socio-economic status, urban habitat and the type of work contribute to
the manifestation of Daurbalya.
•Vata Pittaja & Rajasika Prakriti, Madhyama & Avara Sara, Avara Sattva
were found more prone for the development of Premature Ageing.
•Maximum sign & symptoms of Ageing are related to Dhatukshaya.
The Results in three groups based after subjection to analytical statistical
techniques reveals that:
•Rasayana Yoga Ghana vati with Anupana of Milk Shows better result in
Group „A‟ i.e.40-50 years on cardinal Sign & symptoms in comparison with
other group because of early administration of Rasayana and before all
sign and symptoms of ageing appeared. Administration of Rasayana in
this age group prevents excessive dhatu kshaya and thus prevents
premature ageing and complication of normal ageing process.

110. •Rasayana yoga Ghana Vati shows less result in Group „C‟i.e.61-70 years age
group because at this point of age excessive deterioration of body occurs and its
very difficult to rectify the dhatu kshaya.
•Rasayana yoga Ghana Vati is Vaya sthapana, Brihana, Balya, Rasayana, Deepana,
Pachana, Srotoshodhana, Vata Shamaka properties. Its pharmacodynamic properties
prevent excessive degeneration and slow down the process of Dhatu Kshaya and thus
prevent Premature ageing.
•According to literary profile ,Jara avastha is Yapya so the medication can provide
only symptomatic relief for certain period. But, in premature ageing if Rasayana is
taken at proper age along with good lifestyle and Diet as mentioned in texts as
“Poorve vayasi madhye va” it can prevent premature ageing .
•Though the trial drug of the present study that is Rasayana Yoga Ghana Vati proves to
be effective in sign and symptoms of ageing .it shows better result when administered at
proper and early age before sign and symptoms of ageing gets aggravated.
•The results at the end leads to the conclusion that administration of Rasayana
Yoga Ghana Vati with milk as Anupana along with proper diet ,lifestyle, free from
stress ,some exercise, Yogasans and Medication have certainly a positive role in
inducing satisfactory level of benefits in the management of Jara Roga ,if patients
follow advised regime.

111. Thank U…