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Dr. Nauman Zafar PGR Medicine
Introduction
Etiology
Clinical Presentation
Investigations
Treatment
 Normal Amount of pericardial fluid = 20-50
mL
 The accumulation of fluid in the pericardial
space in a quantity sufficient to cause serious
obstruction to the inflow of blood to the
ventricles results in cardiac tamponade
 Tamponade occurs when long standing or
rapidly formed effusions  increased
pressure in the pericardial space throughout
the cardiac cycle
 Presence of impairment of hemodynamics
by the presence of the fluid in the pericardial
space differentiates it from simple effusion
 There are both limitation of ventricular filling
and reduction of cardiac output
 The quantity of fluid necessary to produce
this critical state may be 200 to >2000 mL
depending upon rapidity of fluid
accumulation
 Neoplasia : Carcinoma lung, Breast,
Hodgkin’s, Mesothelioma
 Idiopathic
 Renal Failure
 Infection :Viral (HIV), Bacterial
(Mycobacterium), Fungal
 Iatrogenic : Cardiac Surgery,
 Drugs : Anticoagulants, Hydralazine,
Procainamide, Isoniazid, Minoxidil
 Post myocardial Infarction :free wall
ventricular rupture, Dressler’s syndrome
 ConnectiveTissue Diseases : Systemic lupus
erythematosus, rheumatoid arthritis,
dermatomyositis
 Trauma
 Dyspnoea
 Chest Pain
 Palpitations
 Tachycardia
 Beck’sTriad : Hypotension, Jugular venous
distention, soft or absent heart sounds
 Pulsus Paradoxus : Fall in BP during
inspiration >10mmHg ( Normal <10mmHg)
 ECG :
 Low voltage
 Tachycardia,
 Electrical alternans ( due to heart swinging
backwards and forwards within a large fluid-
filled pericardium)
CXR:
 Water bottle heart
 Effacement of the normal cardiac borders
 Increase in size of cardiac silhouette
 Echocardiography:
 Pericardial
Tamponade With
Right-Sided Collapse
 Eff = effusion; LA =
left atrium; LV = left
ventricle; RA = right
atrium; RV = right
ventricle
 Right Heart Catheterization:
 Near equalization (w/in 5 mm Hg) of
the RA, RV, PCWP, RV diastolic, & LV
diastolic pressures
 Patients with acute pericarditis should be observed
frequently for the development of an effusion; if a
large effusion is present, the patient should be
hospitalized and pericardiocentesis carried out or
the patient should be watched closely for signs of
tamponade.
 Arterial and venous pressures and heart rate should
be monitored or followed carefully, and serial
echocardiograms obtained.
 If signs of hemodynamic compromise appear
 Pericardiocentesis – Echocardiographically or
fluoroscopically guided apical, parasternal, or,
most commonly, subxiphoid approach must be
carried out at once as reduction of the elevated
intrapericardial pressure may be lifesaving
 IV normal saline
administration
 A small, multiholed
catheter may be left in
place to allow draining
of the pericardial space
if fluid reaccumulates.
Surgical drainage :
 Through a limited (subxiphoid) thoracotomy
may be required in recurrent tamponade,
when it is necessary to remove loculated
effusions, and/or when it is necessary to
obtain tissue for diagnosis
Pericardial fluid analysis:
 Lactic (acid) dehydrogenase (LDH),
 Total protein Glucose fluid-to-serum ratio < 1
 TLC, DLC
 Gram stain
 Cultures
 Fluid hematocrit for bloody aspirates
 Cytology of pericardial fluid to for malignant
cells
Pericardial fluid:
 Exudative
 Neoplasm, tuberculosis, acute rheumatic
fever, post-cardiac injury, post MI
 Transudative
 Heart failure
Cardiac temponade

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Cardiac temponade

  • 1. Dr. Nauman Zafar PGR Medicine
  • 3.  Normal Amount of pericardial fluid = 20-50 mL  The accumulation of fluid in the pericardial space in a quantity sufficient to cause serious obstruction to the inflow of blood to the ventricles results in cardiac tamponade  Tamponade occurs when long standing or rapidly formed effusions  increased pressure in the pericardial space throughout the cardiac cycle
  • 4.  Presence of impairment of hemodynamics by the presence of the fluid in the pericardial space differentiates it from simple effusion  There are both limitation of ventricular filling and reduction of cardiac output  The quantity of fluid necessary to produce this critical state may be 200 to >2000 mL depending upon rapidity of fluid accumulation
  • 5.  Neoplasia : Carcinoma lung, Breast, Hodgkin’s, Mesothelioma  Idiopathic  Renal Failure  Infection :Viral (HIV), Bacterial (Mycobacterium), Fungal  Iatrogenic : Cardiac Surgery,  Drugs : Anticoagulants, Hydralazine, Procainamide, Isoniazid, Minoxidil
  • 6.  Post myocardial Infarction :free wall ventricular rupture, Dressler’s syndrome  ConnectiveTissue Diseases : Systemic lupus erythematosus, rheumatoid arthritis, dermatomyositis  Trauma
  • 7.  Dyspnoea  Chest Pain  Palpitations  Tachycardia  Beck’sTriad : Hypotension, Jugular venous distention, soft or absent heart sounds  Pulsus Paradoxus : Fall in BP during inspiration >10mmHg ( Normal <10mmHg)
  • 8.
  • 9.  ECG :  Low voltage  Tachycardia,  Electrical alternans ( due to heart swinging backwards and forwards within a large fluid- filled pericardium)
  • 10.
  • 11. CXR:  Water bottle heart  Effacement of the normal cardiac borders  Increase in size of cardiac silhouette
  • 12.
  • 13.  Echocardiography:  Pericardial Tamponade With Right-Sided Collapse  Eff = effusion; LA = left atrium; LV = left ventricle; RA = right atrium; RV = right ventricle
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.  Right Heart Catheterization:  Near equalization (w/in 5 mm Hg) of the RA, RV, PCWP, RV diastolic, & LV diastolic pressures
  • 19.  Patients with acute pericarditis should be observed frequently for the development of an effusion; if a large effusion is present, the patient should be hospitalized and pericardiocentesis carried out or the patient should be watched closely for signs of tamponade.  Arterial and venous pressures and heart rate should be monitored or followed carefully, and serial echocardiograms obtained.
  • 20.  If signs of hemodynamic compromise appear  Pericardiocentesis – Echocardiographically or fluoroscopically guided apical, parasternal, or, most commonly, subxiphoid approach must be carried out at once as reduction of the elevated intrapericardial pressure may be lifesaving
  • 21.  IV normal saline administration  A small, multiholed catheter may be left in place to allow draining of the pericardial space if fluid reaccumulates.
  • 22. Surgical drainage :  Through a limited (subxiphoid) thoracotomy may be required in recurrent tamponade, when it is necessary to remove loculated effusions, and/or when it is necessary to obtain tissue for diagnosis
  • 23. Pericardial fluid analysis:  Lactic (acid) dehydrogenase (LDH),  Total protein Glucose fluid-to-serum ratio < 1  TLC, DLC  Gram stain  Cultures  Fluid hematocrit for bloody aspirates  Cytology of pericardial fluid to for malignant cells
  • 24. Pericardial fluid:  Exudative  Neoplasm, tuberculosis, acute rheumatic fever, post-cardiac injury, post MI  Transudative  Heart failure