It takes approximately 10 years for cervical dysplasia to develop into cancer, still one of the most common cancer deaths in women. A yearly PAP test is the most important...

1. It takes approximately 10 years for cervical dysplasia to develop into cancer, still one of the
most common cancer deaths in women. A yearly PAP test is the most important prevention
strategy and a woman has. Cervical dysplasia is treatable if caught early and in its initial
non-invasive stage.
Not all cervical dysplasias will develop into cervical cancer, however squamous cell cervical
cancer is almost always preceded by cervical dysplasia. Similarly, although not all Human
Papillomavirus virus (HPV), a sexually transmitted infection, become cancer or even cause
dysplasia, virtually all of cervical cancers and dysplasias, when present, are caused by HPV.
In other words, cervical dysplasia is a sexually transmitted disease.
At puberty, the cells lining our cervix, change from columnar cells, which line the rest of the
uterus, to squamous cells. This is a very normal process called metaplasia. This junction of
the two type of cells is called the squamo-columnar junction, and it is here that the cells are
most susceptible to another abnormal premalignant transformation (dysplasia). The bottom
layer of the squamous cells is called the basal layer, where the most immature, largest cells
with the biggest nuclei exist. The thickness of the basal layer determines the severity of the
dysplasia (mild – severe dysplasia). In the case of Carcinoma "in situ", the immature basal
cells extend all the way to the very top of the tissue thickness. As the severity of the
dysplasia increases, so does the risk for cancer.
HPV has a number of subtypes that vary in terms of aggressiveness and risk of developing
dysplasia. HPV 16 and 18 are considered to be the most aggressive, accounting for the
largest percentage of cervical cancer cases. Besides HPV, other risks for cervical dysplasia
include prior Chlamydia or HIV infection, obesity, birth before the age of 22, cigarette
smoking, multiple sexual partners, poor nutrition, low socioeconomic status, family history
of cervical cancer, and one proposed risk is the use of oral contraceptive medication. It has
been suggested that, given some of risk factors for cervical dysplasia, an impaired
or weakened immune system may play a role in its development. That being said, when our
immune system is functioning at its optimum capacity, it has the power to fight even the
most severe forms of dysplasia and spontaneous regression is common.
Atypia is a common PAP smear result that is misunderstood by many women. A diagnosis of
Atypia is made when the cells have not changed enough to be labelled as abnormal (or
dysplasia), but are not quite normal, either. Atypia, as mentioned earlier, commonly
regresses on it own. This type of cell is often seen when the tissue is already in the process
of repairing itself. For others, it can be a very early abnormal change and as such, should
always be monitored.
Cervical Dysplasia

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There are a variety of nutritional habits and supplements that can be used to prevent HPV
or treat cervical dysplasia to prevent the development of cervical cancer. Diets high in anti-
oxidant rich fruits and vegetables can significantly reduce the persistence of the HPV virus.
Tomatoes, yellow and orange fruits and vegetables, eggs, dark green leafy vegetables and
papaya are all great sources of these nutrients.
As cervical dysplasias can be an estrogen dominant concern, consuming cruciferous
vegetables such as broccoli, cabbage, brussel sprouts and kale, all high in Indole-3-carbinol,
are useful in prevention of cancer of cervical cancer. This has been shown to help to ensure
that estrogen metabolism is being altered in such a way as to reduce the carcinogenic
metabolites.
Sometimes it can be difficult to ensure adequate fruit and vegetable intake to provide all
required nutrients and antioxidants, so a supplement is can be beneficial for your health
maintenance. Effective supplements for cervical dysplasia include vitamin A, E and C, and
mixed carotenoids; look for Indole-3-carbinal as a supplement.
Homocysteine is associated with a higher risk of developing cervical cancer and can be
produced by vitamin B12 and folic acid deficiency. You can supplement these vitamins orally
as well as through an intramuscular injection. Additionally you can take green tea extract as
a supplement or topically which has shown some promise in cervical dysplasia treatment.
In terms of lifestyle goals to treat and prevent cervical dysplasia, a goal to quit
smoking should be at the top of your list. Smoker are 2-3 times more likely to develop
dysplasia than non-smokers. Again, stress plays a significant role in disease development
and immune function. Use stress reducing techniques and exercises everyday to more
effectively deal with stress. Young women should also be counselled about sex and the
increased risk that unprotected sex, as well as sex with multiple partners at an early age
can have on the development of HPV.
Last but not least, there is evidence suggesting that long term contraceptive use can
predispose women to developing a rare variant of squamous cell carcinoma called
adenocarcinoma. Women on oral contraceptives should be aware that long term use (of 12
years or more) may have negative impact on overall health.
The recently developed HPV vaccine has been shown to effectively decrease the incidence of
HPV. One must always keep in mind that HPV does not always lead to cervical dysplasia and
the vaccine is not aimed at preventing cervical dysplasia or cancer, only the precursor of
HPV.

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Nutritional Information
Supplement Dosage Therapeutic Effect
Vitamin C 2-6 G/Day For Immune System Support. Studies
Show Low Plasma Levels Of Vitamin C In
Cervical Dysplasia.
Mixed Carotenoids 75,000 -150,000 Iu/Day Beta Carotene Deficiency In The Cervical
Cells Plays A Role In The Development Of
Cervical Dysplasia.
Folic Acid 2.5-10 Mg/Day Studies Have Shown That Women On Oral
Contraceptives Taking Folic Acid
Supplementation Saw A Regression Of
Dysplasia, Other Studies Also Show A
Preventative Effect.
Vitamin B12 1000 Mcg/Day Protective Against Cervical Dysplasia
Green Tea Extract 300 Mg/Day Orally. Can Also Be
Used In Suppository Form –
Insert Twice Weekly.
Effective In The Treatment Of Cervical
Dysplasia.
Indole-3-Carbinol Prevents Abnormal Cell Growth And
Tumour Progression In Estrogen Related
Cancers.
Curcumin 350-1000 Mg/Day Preventative Of Cervical Cancer, Down
Regulates The Hpv Virus.
Vitamin A Vitamin A Suppositories Nightly
For A Week, Followed By A
Week Of Herbal Suppository
(Such As Goldenseal Or
Echinacea Or A Combo).
Continue Rotating For 3
Months. Use Under The
Guidance Of Your Health Care
Practitioner.
Used As An Effective Treatment Of Mild-
Moderate Cervical Dysplasia.
For Informational Purposes Only. Please Consult Your Health Care Practitioner Before Taking
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