A 39-year-old healthy woman experienced subcostal rib pain between the T11-T12 vertebrae that worsened with activity and prevented her from jogging. A 49-year-old woman with metastatic breast cancer had severe neck and thoraco-lumbar pain and was classified as ASIA E. A 67-year-old with non-small cell lung cancer who had an upper lobe resection and was oxygen dependent also had severe posture dependent back pain classified as ASIA E, two years after being diagnosed.