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STRONG heart initiative for cardiovascular disease (2)
1. Time
Cardiacfunction
Worsening HF
event
Worsening HF
event
Worsening HF
event
REDUCED Ejection Fraction =< 40%
Chronic Heart Failure
Downward Spiral, Experiencing Repetitive
Worsening HF Events and HospitalizationsMild HF
End-stage HF
Moderate-severe HF
Re-hospitalization
Hospitalization
Death
30 – 50%
Die or Re-hospitalized
within 60 days
20-30%
mortality
after 1 year
40 - 50%
mortality
after 5 years
Re-hospitalizationSudden death
A condition characterized by the progressive decline in heart’s
ability to pump enough blood to supply the body’s needs for
blood & oxygen
What is
Heart Failure?
Dizziness
Shortness of breath
Edema
Chronic coughing
wheezing
HF Conditions
HOW our heart pumps
1- Congestive Heart Failure
The blood flow out of the heart slows & blood returning to the heart through the
veins backs up, causing congestion in the body's tissues
2- Right-sided Heart Failure
The right ventricles are not able to pump the blood properly
3- Left-sided Heart Failure
The left ventricles are not able to pump the blood properly
3A- Diastolic Heart Failure ( HFpEF)
LV muscles becomes stiffer than normal then loses its ability to relax normally
and can't properly fill with blood
3B- Systolic Heart Failure (HFrEF)
LV muscles loses its ability to contract normally or to pump out oxygenated blood
Rapid/irregular heartbeat
Lack of appetite
Etiology Symptoms
Injury
Interrupted
blood supply
Increased
workload
NORMAL Ejection Fraction = 50 - 70%
BORDERLINE Ejection Fraction = 41 - 49%
Heart Ejection Fraction =
amount of blood in the heart
amount of the blood pumped out
https://heart.bmj.com/content/83/5/596
https://www.sciencedirect.com/science/article/pii/S1016731519301095
https://www.mayoclinic.org/diseases-conditions/heart-failure/symptoms-causes/syc-20373142
https://www.heart.org/en/health-topics/heart-failure/what-is-heart-failure/types-of-heart-failure
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803971/#:~:text=The%20extrapolated%20prevalence%20of%20HF,syndrome%20(ACS)%20had%20HF.
Death
The mean age of AHF & CHF
patients
Almost 10 years younger than pts.
from developed countries
Diabetes prevalence
of AHF Saudi patients is
double the rate
reported by the global
Despite the SoC, at One year,
all-cause mortality is
High disease burden on
healthcare costs with annual
Rate of
An Increasing Burden
Estimated incidence is
/Year
>400k
… highly prevalent condition with high morbidity & mortality that negatively
impacts Patient’s longevity, healthcare systems & HCPs
Let’s foSTeR a life-lONG
healthy heart
By:- Mohamed Ibrahim
Seddik