More Related Content Similar to Pc 400 Application _Ashraful (2).pptx (20) 2. ABX Pentra C400
© 2018 HORIBA, Ltd. All rights reserved. 2
2018 PC400 PRESENTATION V1.11
7. 1 Physical specifications
2 Technical specifications
3 Computer specifications
Product Overview
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8. ISE Module
Sample Tray
Reagent Tray
Sampling System
Windows XP
Cuvette Changer
➢ Bench-top analyzer
➢ Dimensions : 100 x 65 x 57 cm
➢ Weight : 120 kg
➢ Screen: 12 inches
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Main features : Benefits
Physical Specifications
Product Overview
9. • Analysis method types:
- Spectrophotometry: Colorimetry and Turbidimetry,
- Potentiometry: Direct (Serum or Plasma) and Undirect (Urine)
• On-board Test Capacity: 55 parameters on board
- 52 cassettes positions or 39 tests positions with Reagent racks
- 3 ISE's (Na+, K+, Cl-)
• Sample Capacity (60 samples on board)
- 6 racks with 10 sample positions for primary tubes or cups
- Continuous loading
- Positive Sample Identification (integrated Barcode Reader and tube presence detector)
• Sample Needle : level detection, shock detection and clot detection
• 52 Reagents sectors : 44 refrigerated (2-10°C)
• Reagent Needle: Capacitive Level detection & Preheating
Main features : Benefits
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Product Overview
10. • Hardware characteristics
Processor : Atom™ 1.46 GHz
Hard drive : 250 GB
RAM : 4GB
RS232C, RJ145 LAN, USB 2.0 (7 ports), Audio
• Operating System
Windows 7 ™
• Software
FULL QC
Validation Station
User’s Channels
Logs
Interactive Help
Main features : Benefits
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Product Overview
12. Software
COMPLETE SOFTWARE
Flexibility:
➢ Id. or pos.: if LIS or not (dedicated, Vet, Industry)
barcode tube or cup position
Easy to use:
➢ Backup: automatic reagent management
automatic recalibration if needed
➢ Create additional automatic filter: for Cal
➢ Automatic maintenance
Quality/traceability :
➢ Automatic data export
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Product Overview
13. Software
COMPLETE SOFTWARE
Flexibility:
➢ Language: English, French, German, Italian, Spanish, Portuguese, Greek & Polis
Quality/traceability :
➢ Automatic database backup (8 working days max)
➢ Manual database backup (to help for support)
(for sales to follow activity)
Product Overview
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14. Software
COMPLETE SOFTWARE
Easy to use :
➢ Mono or Bi directional : ASTM format
➢ Query and Requery possible
Support :
➢ Integrated technical support/tool
Product Overview
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15. Flexibility:
➢ Printer: Customized printout (Logo, header,…)
➢ Printer installation: Only windows Driver required to get manual or
automatic printout
➢ QC Printout: with precision and/or accuracy curve
Easy to use and Secured :
➢ On board a complete validation station
➢ Westgard rules possible
➢ According LIS or not Set what to Review (Quality flag, Delta check,…)
➢ Automatic rerun out of Critical panic range
➢ Automatic post Dilution or post Concentration
Software
COMPLETE SOFTWARE
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Product Overview
16. Software
COMPLETE SOFTWARE
Easy to use and Flexibility:
➢ Customized Audible alert to be well informed on time
➢ Audible message set up by: type, volume intensity,
language,..
Easy to use and secured:
➢ Maintenance Alert can be set according use
➢ Most of the maintenance in automatic : daily & weekly
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Product Overview
17. Quality & Traceability:
➢ Customized by setting the user name and access
➢ Protected instrument use : Automatic logoff after time can be set.
Flexibility:
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➢ Up to 15 User’s channel confiration
(can be extended to 40 according to hardware modifications)
➢ Sales Tool : Test Counter
➢ Perishable management: use of expired (reagents, calibrators,…),…
Software
Product Overview
19. To create empty new
User’s Channel
(for Admin Level)
To see details or modify
unit, ranges,
Control required,…
To Copy a previous
methodology in a new
User’s Channel
(for Admin Level)
To Update/download new
Horiba’s Channels
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To Change test order
(printout & Worklist
selection)
Product Overview
Application
21. Application
Details 1/4
Flexibility:
➢ Pretreatment (predilution) ½ up to 1/22 500
➢ Post Dilution / Post Concentration
➢ Unit selection protected (automatic calculation)
➢ Manual validation Possible (for special test independant
than validation station)
➢ Test name according User’s preference
➢ And activate only required test
Product Overview
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22. Security and rules:
➢ Delta Check or anteriority check
➢ Normal or reference range
➢ Critical rerun range (automatic rerun)
Standardization:
Instrument correlation possible
Product Overview
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Application
Details 1/4
24. Cleaner before or after R1 R1+S R2
Application
Details 2/4
Sequence & wavelength
15 Wavelengths: mono or bi : 340nm …700nm
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Product Overview
25. Time
In second
Reagent
Needle
dispensing
Cycle time 12 second:
■ Volume flexibility: 2µL up to 95µL for Sample Needle
15 up to 600µL for Reagent Needle
➢ Dispensing flexibility: in any cycle new solution (reagent or sample or diluent)
can be dispensed by Needles
➢ Mixing Speed Flexibility: can be set from 0 up to 100%
Sample Needle dispensing
0
Absorbance
measurement
In Cycle
0
(R1 alone
reading)
12
1
(R1 + S
reading)
24 36 48
2 3 4
Product Overview
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Application
Details 2/4
26. Reagent 1
Reagent 2
Sample Reagent 3
Reagent 4
0 12 24 36 48
Time
In second
Product Overview
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Application
Details 2/4
27. Type: ENDPOINT / KINETIC / KINSEARCH
Reading point : 0 to 99 cycles (12s)
Product Overview
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Application
Details 3/4
28. Sample Quality:
➢ Sample limit (interferences)
➢ Reaction limit (substrat depletion)
➢ Antigen excess (hook effect or Prozone)
Reaction Quality:
➢ OD deviation check (div_abs)
➢ Reaction direction (Sign)
Product Overview
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Application
Details 3/4
29. Flexibility: All standard of Biochemistry from Enzyme to DAT &TDM
➢ 3 Calibrator predilutionType
(Factor, Main Direct & Main indirect)
➢ Calibration Mode:
Linear: - Factor
- Slope avg
- Linear regression
Non linear: - Linear inter
- Logit/log4
- Logit/log 5
- Exponen 5
Product Overview
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Application
Details 4/4
30. ➢ Deviation
➢ Factor Checks:
Calibration & calibrator Quality:
Reagent Quality:
➢ Reagent range & Blank range checks:
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Product Overview
Application
Details 4/4
31. Application
PC400 Ratio
Ratio: set calculation between tests
➢ Flexibility : Used when the PC400 is not connected to a LIS
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Product Overview
32. Application
PC400 Profiles
PROFILES: list of tests pre-programmed in the worklist
➢ Flexibility : Used when the PC400 is not connected to a LIS
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Product Overview
34. Application
PC400 Reagent
To change reagent use in Vial or
Cassette
To create new Reagent or Diluent for
User’s channel
Reagent: Select test in cassette or Vial + create new reagent
➢ Flexibility : Reagent format use (small or big consumption)
User’s Channel configuration (Open Channel)
© 2018 HORIBA, Ltd. All rights reserved. 34
Product Overview
36. PC400 Test Menu
Advantages coming from
HORIBA Medical expertise in CC
More than 10 years with the Pentra family
• A complete range ready to use
• Reagent menu allowing the flexibility with 75
applications including:
✓ Enzymes & substrats
✓ Ions & specific proteins as Ferritin, Transf.,
Hapto,…
✓ CRP & CRP-HS
✓ HbA1C
✓ …
Performances
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37. Panels example:
• Hepatic: Total Bilirubin, Direct Bilirubin, Transaminase
ASAT & ALAT, ALP & GGT
• Glucidic: Glucose, HbA1c, Fructosamin
• Lipidic panel: Cholesterol, HDL Chol, LDL Chol, Trigly,
Apo A1 & Apo B
• Bone: Calcium, Phosphorus, ALP
• Cardiac: CK, CK-MB ASAT, LDH, Myoglobin, CRP HS
• Renal: Urea (BUN), Creatinine, Uric Acid, Micro Albumin
• …
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Performances
42. Test Equation
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r2 correlation coefficient
0.9964
ALT Y = 1.00 X + 5.00 (U/L)
CHOL Y = 0.95 X + 0.04 (mmol/L) 0.993
GLUP Y = 0.98 X + 0.04 (mmol/L) 0.9974
CRP Y = 1.03 X - 0.18 (mg/L) 0.997
Correlation
Passing-Bablock regression
Performances
43. Reagent Stability and Sample Volume
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Test Open Stability Sample Volume
ALT 42 Days 20 μL/test
CHOL 48 Days 3 μL/test
GLUP 83 Days 4 μL/test
CRP 64 Days 4 μL/test
Performances
44. Fast Instrument
• Albumin (BCG)
• Glucose (PAP)
• CRP (Latex turbidimetry)
• Complete BMP Panel
Performances
© 2018 HORIBA, Ltd. All rights reserved. 44
45. Reagent range extensions
• DAT & TDM are running on Pentra C400
14 DATs validated: Amphetamine, Barbiturate, Benzodiazepine,
Buprenorphine, Cannabinoid, Cocaine, Ecstasy, Ethyl Alcohol,
Methadone , Methadone Metabolite, Opiate, Oxycodone,
Phencyclidine & Propoxyphene
7 TDMs validated: Acetaminophene, Amikacine, Digoxine,
Gentamycine, Tobramycine ,Tricyclique (Antidepressant) &
Vancomycine
• Up to 15 additional User’s channels
(can be extended to 40 according to hardware modifications)
With Open cassettes 30/10 (ref A11A01922) and Vials can be
used
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Performances
47. • On board Reagent Help
• Website
• International Technical Support
& Etools (For Distributors and subsidiaries only)
Documentation:
Support
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48. • Communication catalogue
• Excel summary file (in Technical Notes)
• Etools Catalogue
(For Distributors and subsidiaries only)
Catalogue information:
Support
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