Testicular tumor

1. CASE PRESENTATION
TESTICULAR TUMOR
Presented By: Dr Lekhraaj Gautam PGT
Department of Pathology
Tezpur Medical College Hospital

2. Clinical History:
 A 25 year old male, presented to surgery OPD
with a history of testicular swelling since last 6
months.
 It was painless ,gradually increasing in size and
not associated with any trauma.
 No H/o undescended testis present.
Following which, partial orchidectomy was done.

3. Radiological findings:
USG
cystic with heterogeneous echoes in the fluid

4. Biochemical findings:
 All parameters were within normal limit.
 Serum markers( β HCG and AFP) not done.

5. Grossing:
Received a specimen labelled as left testicular tumor with
spermatic cord.
Measurement of Testis : 12×7×5 cm3
Spermatic cord : 10 cm in length
External Surface : Lobulated and capsule intact.
Cut Section : Multiple cystic areas noted containing serous fluid.
Largest cyst measuring 3×2 cm2
Greyishwhite solid area noted(2.5× 1 cm2)
Multiple random sections taken form solid and cystic areas.

7. On Scanner View:
Variegated tissue seen in section comprising of cartilage,
glandular epithelium, skin adnexal structures, multiple
epithelial tissues, rhabdoid( skeletal muscle) differentiation.
The cartilage is mature looking but other epithelial structures
including rhabdoid are immature or primitive.
No other germ cell component is seen after extensive
sectioning.

8. Histopathological examination:
On Scanner View:

13. Scanner view:
Individual cells are large with well
defined border, abundant
eosinophilic cytoplasm with
striation and prominent nucleoli.

14. Microscopy:
Multiple sections examined.
Section shows the features of teratoma of testis.

16. Postpubertal type
•Demonstrate varying degrees of atypia
•Any type of tissue may be present, such as gastrointestinal glands,
respiratory epithelium, cartilage, squamous epithelium with
keratinization, primitive undifferentiated spindle cells, or
neuroepithelium
•Will have GCNIS
•Associated with atrophic testis with sclerosis and microliths.

17. Prepubertal type
•More likely to have tissue arrangements mimicking organs
(organoid morphology with tissue layers visible such as
epithelium, lamina propria and muscularis propria) but any
tissue type may be present.
•Hair follicles may be seen (not in postpubertal type)
•No cytologic atypia, GCNIS or necrosis; minimal mitoses

21. Teratoma ovary Teratoma testes
Age: 20-30 yrs
Mature and immature
Hair, sebaceous material is commonly
found
Usually not mixed with other germ cell
tumors
Pre pubertal and post pubertal
Although can be classified as mature
and immature no prognostic significane
Rarely found
Uasually mixed with other other germ
cell tumor( post peubertial)