This Newsletter is Published by the SEARCH (Students Enriching Ayurveda Research and Convenient Health) students club. This club is intended primarily for Ayurveda students & doctors who wish to take up systematic reviews along with interested ones on research works & an expert who has experience in doing such reviews. We wish to structure the protocol by incorporating the principles of Ayurveda, The search strategy will include an extensive listing of eastern databases and hand searching. In Ayurveda, the titles of articles are not in the Population, Intervention, Control, and Outcome (PICO) pattern and sometimes the title and methodology do not tally. Therefore, a search of all types of studies is necessary to pool all the relevant publications. A data extraction form is needed to be proposed for use in assessing the quality of Ayurvedic studies. I hope the protocol provides a template for performing evidence reviews of Ayurvedic interventions.

1. SEARCH
NEWSLETTER
ESTD: 2011 A.D
TALK OF
THE
MONTH
MANISHA
DHAKAL
Potential for supportive
Ayurvedic care in
hypoxemic COVID-19
patients ........Pg.02
20 th Batch
AYURVEDA CAMPUS
MAY 2021
Wound healing potential
of bark paste of Pongamia
pinnata :......Pg.04
Benefits to Being an
Early Riser
....... Pg.06
क बता "युवा"
✍ ेम राज जोशी ... Pg. 09
Talk of the month E14
Master the basics. Be at ease
with yourself and where you
are in life and don't stop the
effort.

2. The second wave of COVID-19 has overwhelmed
the Health Care system. The system is gasping for
breath and hospitals are struggling with oxygen
shortage, crunch for beds and ICU facilities with
ventilator support. There are frequent reports of
patients dying at home, on the road or in hospital
corridors due to inadequate access to oxygen
support and institutional care.
POTENTIAL FOR
SUPPORTIVE AYURVEDIC
CARE IN HYPOXEMIC
COVID-19 PATIENTS
PAGE 02
Jyoti Joshi Unnikrishnan Payyappalimana
Rammanohar Puthiyedath
The Ministry of AYUSH has issued guidelines for
practitioners who are treating COVID-19 patients[1].
There are anecdotal accounts of patients getting
benefitted by Ayurvedic interventions in severe
hypoxic conditions.
The purpose of this short communication is to
recommend further studies to explore the
integration of a specific Ayurvedic intervention in
early stages of decreasing peripheral oxygen
saturation levels. Due to the unprecedented
challenge posed by the escalation of the pandemic,
Ayurveda physicians are caring for COVID-19
patients in intensive care settings with the consent
of the patients as well as treating physicians or in
home settings with the consent of the family
members as add on therapy.

3. 2. A 75-year-old gentleman with diabetes was admitted to hospital due to worsening symptoms after testing
positive for COVID-19 (01/04/21). He was discharged after two weeks (16/04/21) and was advised home
oxygenation for 30 days as his pulse oximetry readings fluctuated between 80 and 85%. He was advised to
follow up after a week. Five days after discharge (21/04/21), the patient approached the first author of this
communication and was administered Ayurvedic medicines sublingually. In about eight hours, the oxygen
saturation increased to 89 from 91% and in the next four hours to 95%. On the third day of starting
Ayurvedic treatment, oxygen saturation was found to be maintained at 97% (23/04/21). Oxygen
supplementation could be completely withdrawn, three weeks earlier than recommended, and within three
days of initiation of the Ayurvedic treatment. The patient is recovering and is continuing the Ayurvedic
medications.
3. A 45-year-old female was tested positive for COVID-19
with symptoms like loss of smell and taste, fatigue, body
ache and breathlessness on exertion. Oxygen saturation
levels decreased to below 90% and the patient complained
of increasing breathing difficulty. She approached the first
author for Ayurvedic treatment (11/04/2021). In about six
hours after initiation of Ayurvedic treatment, the pulse
oximetry reading improved to 93% and within twelve hours
to 95%. The patient also reported symptomatic
improvement. Five days later, the SpO2 reading was 96%
(16/04/2021) and two weeks later, the patient was found to
be asymptomatic and oxygen saturation was well
maintained at 97% (25/04/2021).
The recommendations are based on outcomes
observed in several patients with low SpO2 readings
following continuous sublingual administration of
classical Ayurvedic formulations like Shaddharana
Churnam, Apamarga Ksharam, Pippali Churnam,
Rasasinduram and Naradiya Lakshmi Vilasa Rasam
in divided microdoses. The Ministry of AYUSH is
dynamically updating the classical Ayurvedic
formulations that are used by Ayurvedic practitioners
for management of COVID-19.
PAGE 03
1. A 34-year-old male presented to the first author with
breathlessness and oxygen saturation levels dipping
below 90% (30/09/20). Within three hours of sublingual
administration of Ayurvedic medicines every 10
minutes, SpO2 readings improved to 94%. The next
day, the readings were in the range of 95-97%
(01/10/20). Subsequently, it was well maintained at 98-
99% (02/10/20) and the patient recovered. This
particular patient was treated during the first wave of
the pandemic in India and has a long follow up
without any further deterioration or complications.
Based on the observations in these patients and many
others, the beneficial outcomes of Ayurvedic interventions
in hypoxia seem to have the potential to supplement
standard of care for COVID-19.
Such interventions could minimize the burden on intense hospital care by reducing the need for oxygen
supplementation. It has also been observed in other patients that Ayurvedic intervention in early stages of
decreasing peripheral oxygen saturation can possibly prevent the need for oxygen supplementation and
hospitalization.

4. Chronic wound is one of the leading causes of
amputation worldwide. Successful management of
chronic wounds has become a challenge to all
existing medical systems across the world. Sri
Lankan Traditional and Ayurvedic medicine
reveals many promising herbal and alternative
remedies for chronic wounds
Introduction
Chronic wound is a persistent wound and it
doesn’t heal in an orderly set of stages within a
predictable time frame. They often remain in the
inflammatory stage for a lengthy period of time
and are frequently susceptible for the
suppuration by microorganisms. Streptococcus
sp. and Staphylococcus sp. are predominant and
colonization and infection may further delay the
healing process.
PAGE 04
Wound healing potential of bark paste of Pongamia pinnata
along with hirudotherapy
We hereby report a successfully managed case
of an 80-year-old female patient suffering from a
chronic wound for two years, when presenting has
advised for amputation of the leg. The treatment
protocol included the application of hirudotherapy
along with the bark paste of Pongamia pinnata
followed by Flueggea leucopyrus with
recommended other external and internal
remedies. At the end of the treatment protocol,
pain, exudates, odor, burning sensation, and
itching were reduced completely while swelling
and wound size was reduced remarkably and
showed significant healing in the wounded area.
Hirudotherapy is a common intervention in
Ayurvedic medicine while the herbal treatment
of Pongamia pinnata traces its origin in
traditional medicine of Sri Lanka. Flueggea
leucopyrus is used in both Ayurvedic and
traditional medical systems of Sri Lanka.
Therefore, this treatment modality is a
combination of traditional and Ayurvedic
medicine practiced in Sri Lanka. Applying
medicinal Leeches (Hirudo medinalis) for
bloodletting purposes has become one of the
most effective treatment methods, mentioned in
Ayurveda in the management of chronic
wounds. According to traditional ayurvedic
records leech therapy has been described as an
effective treatment which can be applied in all
inflammatory, suppurative and painful
conditions to relieve pain and to inhibit
suppuration. Medicinal leeches drain impure
blood and enhance the healing process.
Chronic wound patients often report pain as a
dominant complaint in their lives’ and persistent
pain and associated discomfort may greatly
hamper the lifestyle of the affected individual.
The treatment protocol used in this case is not
recorded as it is in traditional or Ayurvedic
medicine of Sri Lanka. However, the Ayurvedic
clinician who met the case has correlated the
benefits of familiar individual treatments
(hirudotherapy, application of bark paste and leaf
paste of Pongamia pinnata and Flueggea
leucopyrus respectively) to formulate the
modality with specific time windows and has
treated the patient.
Patient information
An 80-year-old female patient presented to the
clinic for treatment complaining of a non-
healing wound which involved anterior tibial
aspect of the right lower limb and around right
ankle. She complained of burning sensation,
pain in the wound, foul-smelling, pus discharge,
difficulty in walking and itching. On
examination a large wound (13 × 5 cm) was
observed on the anterior side of the right leg,
from the knee to the ankle joint. Local swelling
was also noticed on examination. Past history
revealed nothing about major systemic diseases
or surgery. She had undergone many treatments
throughout but was not successful and
presented to the Gampaha Ayurveda clinic,

5. The second week onwards Triphala kwata was
used as an internal medicine. Triphala kwata
stimulates appetite, improves proper digestion
and absorption of food, improves circulation
and wound healing. Fifth and sixth week Laghu
manjishtadi kwath was used to purify blood and
to correct vitiation of Mamsa dhatu. In this
treatment protocol the external drugs were
applied during first week intending purification
action. Second and third week external drugs
have been applied to relieve burning sensation
and eliminate more pus. From the fourth week
onwards, fresh bark powder of Pongamia
pinnata mixed with pinda oil was applied on
wounds once a two day. Pongamia pinnata
dressing was continued until complete healing
was achieved and the result was assessed at
regular intervals. Furthermore, application of
the bark paste of Pongamia pinnata markedly
reduced the size of the wound as expected. Since
the healed area of the wound showed a mild
overgrowth, at the 8th week, paste of leaves of
Flueggea leucopyrus was applied expecting a
scraping action (which exerted Lekhana action).
Therapy and timeline
Pancha mooli laghu kwath, Triphala kwath and
Laghu manjishtadi kwath 30 ml each, morning
and evening after food was used as the internal
medicine. Treatment modality was continued for
eight weeks and consisted of traditional
ayurvedic internal medicines and external
medicines. Bark paste of Pongamia pinnata, paste
of the leaves of Flueggea leucopyrus and
hirudotherapy are interventions added to the
treatment modality. Hirudotherapy (Hirudo
medicinalis) was continued once a week
throughout the treatment period; application of
bark paste of Pongamia pinnata continued for
four weeks (4th to 7th week) and in the last week
of the treatment, the external therapy was shifted
to the topical application of paste of the leaves of
Flueggea leucopyrus.
Discussion
The traditional approaches of vrana consist of
shodhana (purification), srava hara (pus
elimination), daha hara (relieve burning
sensation) and ropana (healing).n a theoretical
approach, before applying a specific wound
healing drug, it is necessary to clean the wound.
Therefore, the wound was cleaned with the
decoction of Panchavalkala. Recommendation of
internal medicine had several aims. Intake of
Pancha mooli laghu kwata as the first week and
second week treatment was set in order to purify
the body.
Hirudotherapy (Leech therapy) is one of the
oldest practices in medicine; it is known from
the time of extreme antiquity and is still alive in
Sri Lankan traditional medical system. During
feeding, leeches secrete a complex mixture of
different biologically and pharmacologically
active substances into the wound and hirudin is
the prominent constituent of leech saliva. These
substances possess analgesic, anti-inflammatory,
platelet inhibitory, anticoagulant, and thrombin
regulatory functions, as well as extracellular
matrix degradative and antimicrobial effects.
Evacuation of impure blood from the wound
improves the process of wound healing and it is
assumed that the procedure will complement
and enhance the efficacy of other treatments.
Conclusion
With presenting case, the treatment protocol
comprising leech therapy, bark paste of
Pongamia pinnata and paste of leaves of
Flueggea leucopyrus was very effective and
shown excellent healing effect in chronic and
nonhealing wound. Evidence based non-surgical
alternative remedy and impressive out come of
this treatment protocol could be an interesting
approach in the management of chronic wounds
Western Province, Sri Lanka; at the time she was
advised for amputation.
Clinical findings
Patient was anxious at the time of presenting. She
had normal rhythmic pulse, 80/min and
respiratory rate, 20/min. Blood pressure was
110/80 mmHg and weight was 60 Kg. Body
temperature was 98.4 °F.
PAGE 05
Pancha mooli laghu kwath was given expecting
shodhana guna (Purification). It detoxifies the
body by removing vitiated doshas through
purgation. Triphala kwath has many actions on
the body. It stimulates appetite, improves proper
digestion and absorption of food, improves
circulation and wound healing. Laghu manjistadi
kwath purifies blood and helps to correct
vitiation of Mamsa dhatu.

6. Benefits of waking up Early
i) Meditation at this time improves mental performance thus helps in increasing satva guna therefore
subduing mental irritation or hyperactivity and lethargy which is contributed by rajas and tamas guna.
ii) In the early morning, Earths vibration is very low along minimum pollution (noise, water, air) which
enhances the concentration. Along with the clean air, pleasant atmosphere, absence of noise, the morning
rays of rising sun is very beneficial
iii) Last part of night is dominant by vata dosha, which helps in elimination of toxins and evacuation of
bowel along with body movements and functioning of organs.
iv) There is release of Nascent oxygen (otri) in the atmosphere in the early morning easily and readily mixes
up with hemoglobin to form oxy-hemoglobin which nourishes the remote tissues rapidly.
v) Exposure to bright light in early morning causes the release of serotonin (Happy hormone) keeps the
person active and alert and make enthusiastic whole day.
vi) Early morning is the time when secretion of cortisol hormone is maximum. Cortisol is a steroid hormone
that regulates the wide range of processes throughout the body, including metabolism and the immune
response. It also has a very important role in helping the body in response of stress.
vii) Stimulates to production of melatonin (Mood elevator), which gives prime health throughout the day.
Ayurveda believes that routine is a discipline for the body and mind which strengthens immunity and
purifies the body of its wastes. With the help of simple healthy routines, one can clean the body and mind,
balance . doshas., strengthen immunity and start the day on a refreshing and rejuvenating note. Ayurveda
recommends an auspicious time “Brahma Muhurata” which means “the time of Brahma” the pure
consciousnesses – for rising up in the morning. Between 4 -6 am in the morning or 1 muhurta before sunrise
(ie about 48 to 96 min before sunrise)
BENEFITS TO BEING AN EARLY RISER
Early to bed and early to rise, makes a man healthy, wealthy, and wise"
- Benjamin Franklin
PAGE 06
ा मु त उ ेत् व ो र ाथमायुषः।।
A healthy person should arise from sleep at Brahma muhurta for preserving the whole life span, wisdom
and happiness.
NOTE: Late night sleeping or chronic sleep loss causes the elevation of cortisol which in turn is
responsible for rise in B.P (secondary hypertension) and is likely to promote the development of
insulin resistance, a risk factor for obesity and diabetes.

7. Q. HOW DO YOU DEFINE YOURSELF?
My favourite pastime is enjoying good music.
Listening, singing and dancing like there is no
tomorrow relieves me from every worry I have.
I don't think I will be able to label any of my habits as
good or bad because all of my habits act as both
according to the situation. But if I have to say my
habit of being curious and habit of being dedicated to
something I love doing might count as good.
Sometimes I am quite impatient and sometimes quite
lazy both are my bad habits.
Personally I would say I am a person who has all
shades of colour spectrum. I may be brightest some
days and be dullest some days and some days I am
somewhere in between.That is all I identify by.
Q.WHAT ARE YOUR FAVORITE PASTIMES?
PLEASE ENTAIL YOUR GOOD AND BAD HABITS.
quite interesting but when I saw the Sanskrit subject
in the syllabus I was very fast to judge and thought
that was not my cup of tea. After some days, as I was
doing my entrance preparation classes in NAME, it
was announced that there was going to be a seminar
about the BAMS course from the experts of the
Ayurveda field. I don't know why but I thought I had
to be there. So I attended the seminar. In those 2-3
hours I had made up my mind that I was going to
study Ayurveda and this is where I belong. So after
that, I studied, appeared on the entrance
examination. Luckily, I got selected and well here I
am now after almost 6 years of knowing, learning
and living Ayurveda.
PAGE 07
There are many memorable incidents but one of the
earliest and impactful memorable incident was our
ragging day. When I first entered the college I had
no idea about this but on a certain day our seniors
called us all in a hall .We were terrified at first but
gradually the environment became very funny .It
was not like any ragging I imagined .Later it turned
into a very happy event. I got to know all the
seniors .That was the day I realised the core of
ACTH was student bond as friends as seniors as
juniors.
I cannot name a single person ,there are so many. I
admire many people for being who they are and
enriching my life as friends as seniors and juniors.
Q. AMID THE PANDEMIC, YOU ARE ON YOUR DUTY.
HOW CHALLENGING IS IT DURING THIS TIME?
The times are challenging for everyone.
I am on OPD duty so comparetivly its not as risky as
working in Isolation centers or ICU but we also see
Covid patients in OPD basis so we have some safety
concerns.We are following proper guidelines and
seeing people getting better and feeling better
makes us feel better so I am sure this challenge will
also be completed successfully.
Q. WHO IS YOUR FAVOURITE INDIVIDUAL IN ACTH?
WHAT NATURE OF THEM INTRIGUES YOU?
Q.HOW DID YOUR JOURNEY COMMENCES IN
BAMS? WOULD YOU LIKE TO SHARE A
MEMORABLE INCIDENT FROM ACTH?
After finishing my +2 while searching for my career
options on the internet I came across BAMS. I found it

8. Actually, the things we study in theory and that we
practise clinically are not that different, the only
difference is our own interpretation and observation. If
you are a conceptual student, you will be a good
clinician.
I would aspire to learn conceptually while studying and
practice with flexibility and use my own intelligence in
clinical practice.
Being part of Fsu was an honour but extremely
difficult .We had to function in between the
pressure of students and administration. Our voices
were not heard sometimes so we had to resist the
administration and make them feel our presence.
Amist all pressure and extra work we had some
major achievements like establishment of girls
hostel ,organising and execution of sports week
yearly , welcome and farewell programs etc.So
overall I think we did pretty good.
Q.YOU WERE A PART OF FSU. WAS IT
DIFFICULT OR WERE YOUR VOICES HEARD?
Q. DURING YOUR DUTY, HOW VARIED ARE THE
CLINICAL PRACTICES FROM WHAT YOU'VE
STUDIED? WHAT CHANGES WOULD YOU ASPIRE TO
BE MADE BOTH CLINICAL AND STUDY-WISE?
PAGE 08
Q.WOULD YOU LIKE TO CONVEY SOME MESSAGES
TO THE UPCOMING GENERATION?
Don't stress over things you know and don't know. Try
to learn and understand concept and context. Master
the basics. Be at ease with yourself and where you are
in life and don't stop the effort.
For a chance to be possible, there must be an effort.
Changes we want rarely happen naturally. So don't
underestimate the power of an effort.
Q. AS YOU HAVE DUTY IN TUTH, WHAT
INFORMATIONS WOULD HAVE BENEFITED YOU IF
YOU HAD ITS KNOWLEDGE BEFORE? WHAT NICER
FACILITIES WOULD YOU LIKE TO SEE THERE?
I am still learning so having knowledge before or after
is not that relevant .The things you don't know you get
to know during practice under experienced doctors.
I would like to see overall development of our hospital
so patients can benefit more .
Every human being and every dravya is different and so in Ayurveda,
there is no patent medicine.

9. बेरोजगारी हटाइदे, युवाको :ख घटाइदे
UK,US होइन मेरो देशलाइ नेपाल बनाइदे
आ दोलन न क त गनु बो नु सबै बेकारछ
देशको मे द ड युवा ड ेसनको शकार छ
क
ृ ट भट देखाउने उमेरमा वदेश जानहतार छ
दसबा क ा प ढस यो डे टनेशन कतार छ।
भ व य हो युवा,वतमान न युवा हो
समृ न कने युवा,एउटा ग हरो क
ु वा हो
वकास देशको हलो,युवा यसको जुवा हो
अथत धा स ने युवा ब लयो टेवा हो।
बेरोजगारी हटाइदे,युवाको :खघटाइदे
UK,US होइन मेरोदेशलाइ नेपालबनाइदे।।
LITERATURE
युवा
✍ ेम राज जोशी
२४ ाच
PAGE 09
बेरोजगारी हटाइदे, युवाको :ख घटाइदे
UK,US होइन मेरो देशलाइ नेपाल बनाइदे ।।
कानुन,अथशा ,जना लजममह व न दएको
एसईईपास गय साइ स नैहो लएको
IELTS ग रअ े लया,साउद तर खाडीमा
बेरोजगारयुवा सबैदेशको पानी पएको ।
बा-आमा घरमा ए लै छन,भाइब हनी अझै पढ्दैछन
ज मेवारी झन बढ्दैछन
बदेश नगइ बसु भने नेतासधै लड्दैछन।
हमाल,पहाड,तराइ; पयटन स ावना
क
ृ षलाई नै जोड दऔ, क
ृ ष हा ो गहना
शा ती जु ो, सं वधान छ, च दैन है बहाना
ब मु य ज डबुट नयात गन चाहना
टाचार,बला कार सम या यहाँ उ तैछन
बेरोजगारी मुख हो,समाधानत तै छन
काम गछु भ े म तै छन, नेताह चोरफटाहा
गु डाकम ज तैछन ।
संस दय यव ा छ ,स ामा बुढाघटाइदे
सं घयता व त गर,युवा नेतृ व बढाइदे
बेरोजगारीहटाइदे ,युवाको :खघटाइदे
UK,US होइनमेरो देशलाइनेपाल बनाइदे।।