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Alkylating agents such as ethylmethane sulfonate (EMS) tend to react q.docx

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KevinxEwStewarth

Alkylating agents such as ethylmethane sulfonate (EMS) tend to react quite readily with O6 of guanine, a strong nucleophile. Illustrate with a resonance structure why this carbonyl oxygen is unusually nucleophilic. Alkylating agents such as ethylmethane sulfonate (EMS) tend to react quite readily with O6 of guanine, a strong nucleophile. Illustrate with a resonance structure why this carbonyl oxygen is unusually nucleophilic. .

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Alkylating agents such as ethylmethane sulfonate (EMS) tend to react quite readily with O6 of guanine, a strong nucleophile. Illustrate with a resonance structure why this carbonyl oxygen is unusually nucleophilic. Alkylating agents such as ethylmethane sulfonate (EMS) tend to react quite readily with O6 of guanine, a strong nucleophile. Illustrate with a resonance structure why this carbonyl oxygen is unusually nucleophilic.

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