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PRESENTING BY
JAGDISH MOURYA
7TH SEM
 DEFINITION OF PEPTIC ULCER
 LOCATION & SYMPTOMS
 CAUSES
 COMPLICATIONS & TREATMENT
 PRECAUTIONS
• PEPTIC ULCER IS AN OPEN SORE IN THE
LINING OF STOMACH AND UPPER PART
OF DUODENUM ESOPHAGUS.
ULCER MAY BE FOUND :
IN ESOPHAGUS
IN STOMACH
IN DUODENUM
IN JEJUNUM AT MULTIPLE LEVELS
PAIN OR DISCOMFORT IN THE UPPER ABDOMEN
LOSS OF APPETITE
NAUSEA AND VOMITING
FATIGUE
STRESS INCREASES HYDROCHLORIC ACID SECRETION.
 USE OF NSAID DRUGS
CHRONIC USE OF NON STEROIDAL ANTI INFLAMMATORY DRUGS LEADS TO
DAMAGED OF MUCUS LINING OF STOMACH.
 ALCOHOL INDUCING ULCER
ALCOHOL INTAKE DISRUPTS MUCUS SECRETION AND CAUSE MUCOSAL DAMAGE
 H. PYLORI (HELICOBACTER PYLORI)
HELICOBACTER PYLORI (H. PYLORI) IS A TYPE OF BACTERIA. RESEARCHERS BELIEVE
THAT H. PYLORI IS RESPONSIBLE FOR THE MAJORITY OF PEPTIC ULCERS, AS WELL
AS CHRONIC GASTRITIS (INFLAMMATION OF THE STOMACH LINING) AND
POTENTIALLY GASTRIC CANCER.
 OTHER CO-FACTORS
CIGARETTE
COFFEE
SPICY FOOD
JUNK FOOD
INTERNAL BLEEDING
BLOODY STOOL
WEIGHT LOSS
GASTRIC CANCER
IRON DEFICIENCY ANEMIA
 H2 ANTI HISTAMINIC DRUGS
• CIMETIDINE
• RANITIDINE
• FAMOTIDINE
 PROTON PUMP INHIBITORS
• OMEPRAZOLE
• PANTOPRAZOLE
• LANSOPRAZOLE
 GASTRIC ACID NEUTRALIZER (ANTACIDS)
• SODIUM BICARBONATE
• SODIUM CITRATE
• MAG. HYDROXIDE
• CAL. CARBONATE
 ULCER PROTECTIVES
• SUCRALFATE
• COLLOIDAL BISMUTH (CBS)
 ANTI H. PYLORI DRUG
• AMOXICILLIN
• CLARITHROMYCIN
• METRONIDAZOLE
• TETRACYCLINE
Causes, Symptoms and Treatment of Peptic Ulcer

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Causes, Symptoms and Treatment of Peptic Ulcer