Created for MiT's 2016-2017 Design Challenge on Infant Mortality. Light and colorful theme allows emphasis to be placed on lightly edited photographs & factual information.

1. The Strength of
Progesterone
Matthew Hammond, JaydenToomer, Ryley BOC,Teague Kuhn.

2. Infant Mortality Is:
•The death of children under one year of age
•Measured as amount of deaths per 1,000 live
births
•Ohio rate: Seven per thousand.

3. Our Objective:
Decrease the infant mortality
rate for premature babies
through the development and/or
administration of a medication.

4. Largest Cause of Death
•Preterm Birth
•Largest fatal complication in children
•Effects one out of eight US deliveries
•Factors into 85% of Infant deaths

5. Rekha Murthy Real-life impact

6. at Risk for Preterm Birth
•Co-pay changed from $5.50  $70 per dose
•No Insurance? Cost ranges between $32 & $855
•Medical listing price is ~$700 per dose
•Why so much?
•Drug Quality and Security Act

7. Method of
Administration
Pros and Cons in the Medical World
July 22, 2012 Footer text here7

8. Pre-Birth Substance
consumed by mother or
injected into fetus via IV.
(Prevent the issue) IV Bolus,
Rapid injection
Less dense liquids
Speedy Effects
Would be used to delay labor –
similar to an Epi-Pen
OR
Used for at-home dosage
injections.
IV Drip,
Slow but safer, requires more time in
hospital and usually costs more.
Could be used to encourage bone and
organ growth – as damage control.

9. Imitates natural hormones from fetus,
Delays birth,
Reduces risk of miscarriage and early
births.
Progesterone
July 22, 2012 Footer text here 9

10. Novartis
“We deliver better outcomes for patients
through science-based innovation in
growing areas of healthcare.”

11. Thanks!
Any questions?

12. Sources
- Hendrix, L. (2015, June 5). Mom hopes baby's co-sleeping death warns others. Retrieved January 19, 2016.
- Jackson, A., & Lumpkin, D. (2009, October 1). Infant Deaths from All Causes. Retrieved January 19, 2016.
- Liquid Extracts vs Capsules/Tablets. (2015). Retrieved January 25, 2016, from http://hhcextracts.com/liquids/
- Murthy, R. (2014, May 27). Pregnancy Woes: Why DidThe Price Of My Progesterone Skyrocket? Retrieved March 16, 2016.
- Norwitz, E. R., & Caughey, A. B. (2011). Progesterone Supplementation and the Prevention of Preterm Birth. Retrieved
January 25, 2016.
- O'Brien, E. (2011, April 11). Makena Backlash & Potential Impact on the Rare Disease Community. Retrieved March 16, 2016,
- Our Work. (2016). Retrieved March 23, 2016, from https://www.novartis.com/our-work
- Premature birth. (2014, November 27). Retrieved January 19, 2016, from http://www.mayoclinic.org/diseases-
conditions/premature-birth/basics/complications/con-20
5020050
- Progesterone. (2015). Retrieved March 16, 2016, from http://www.chemspider.com/Chemical-Structure.5773.html
- Reekie, K. (2014). Hello hormones…. Retrieved March 23, 2016,
- 2013 Ohio Infant Mortality Data: General Findings. (2013). Retrieved January 19, 2016, from
http://www.odh.ohio.gov/~/media/ODH/ASSETS/Files/cfhs/InfantMortality/2013 Ohio Infant Mortality Data Report
FINAL.pdf