Presentation from OIS@ASCRS 2016 Mark Packer, MD, Chief Medical Officer Video Presentation: https://www.youtube.com/watch?v=CWwqmEDJOhM&index=20&list=PL1dmdBNnPTZJBhQxPOp0vdNg3s3wtN2yw

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The integrated ecosystem of today’s ophthalmic
practice
Cassini Presentation - COMPANY CONFIDENTIAL – April 2016

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Growing the premium cataract channel
2015: Toric IOLs
accounted for 3.7% of
all IOLs Implanted
Worldwide1
… it could be 50%2
1 Source: MarketScope report 2015
2 Source: Hill Distribution Data. Provided courtesey of Dr. Warren Hill

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Integrated ecosystem in cataract surgery:
Seamless interaction between clinic and OR
1
Pre Op Diagnostics &
IOL selection
23
4
Post Op Analysis &
SIA management
Patient
Refractive Outcome
Surgeon
Results &
Efficiency
Femto enabled AI’s
Guidance &
verification

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23
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Cassini integrated technology
makes our partners more successful
Erik-Jan Worst
CEO & President, Ophtec
“The combined offering of
Cassini with Ophtec’s
Precizon Toric IOL has
allowed us to grow our
market share and help our
customers with a total
astigmatism management
solution"
Denise Visco
Eyes of York, York, PA
“The addition of Cassini and
Streamline has provided such
great, predictable outcomes that I
use arcuate incisions on most of
my patients with less than
1.7D. This improves efficiency,
reduces costs and increases
conversion of patients to the
premium channel”

5. Cassini Total Corneal Astigmatism
GPS-like data from anterior & posterior cornea
Multi-colored LED
point-to-point ray
tracing
2nd Purkinje point-to-
point ray tracing
technology

6. • Retrospective chart review
• 35 consecutive cases with toric IOL implant
• Preoperative measurements
o Cassini TCA based toric IOL axis and power
selection
• Postoperative residual refractive astigmatism
Cassini Outcome Study
Dr. Elizabeth Yeu, Virginia Eye Consultants

7. Astigmatism Correction with Cassini TCA
Pre-Op Total Corneal Astigmatism 95% Limits of
agreement
n = 35

8. Astigmatism Correction with Cassini TCA
Post-Op Residual Astigmatism 95% Limits of
agreement
n = 35

9. Cassini TCA v ORA – published data
ORA - Hatch et al
JRS 2015
< 0.5D
n = 37
94.2%
82.1%
78.0%
50%
75%
100%
Lenstar + Barrett
Nomogram
< 0.5D
n = 28
Cassini TCA
< 0.5D
n = 35

10. • Physician owned ASCs treat about 1000 pts/ year1
• High-volume centers have about 20% conversion to toric
IOL  200 patients
• Total cost of enhancement is about $2,000.00
– Tangibles and intangibles
1 Source: MarketScope report 2013; 2 Source: Hatch et al. Journal of Refractive Surgery April 2015; 3 Based on assumed
enhancement costs $2.000 per patient; 4 Retrospective study from Elizabeth Yeu – Cassini data on file
IOL selection with ORA2
• 78% within 0.5D RRA
• 44 Patients > 0.5D RRA
• Potential enhancement cost $
88,000.003
IOL selection with Cassini TCA4
• 94% within 0.5D RRA
• Only 12 patients > 0.5D RRA
• Potential enhancement cost $
24,000.003
Economics of getting it right

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