Elsevier is a global information analytics business that helps institutions and professionals progress science, advance healthcare and improve performance for the benefit of humanity. Elsevier provides digital solutions and tools in the areas of strategic research management, R&D performance, clinical decision support, and professional education; including ScienceDirect, Scopus, Scival, ClinicalKey and Sherpath. Elsevier publishes over 2,500 digitized journals, including The Lancet and Cell, more than 35,000 e-book titles and many iconic reference works, including Gray’s Anatomy. Elsevier is part of RELX Group, a global provider of information and analytics for professionals and business customers across industries. www.elsevier.com About Reaxys Reaxys retrieves literature, compound properties and chemical reaction data faster than any other solution and, together with RMC, offers pharma companies a ‘one stop shop’ chemistry ecosystem thanks to its integration capabilities, innovative APIs, and bioactivity data. The Reaxys platform contains over 240 years of unparalleled chemistry content, including: 119 million organic, inorganic and organometallic compounds, 46 million chemical reactions, 500 million published experimental facts, 16,000 chemistry related periodicals, and six indexing sources for a cross-disciplinary view of chemistry. RMC offers access to data from a vast repository of peer-reviewed journal articles and patents and is interoperable with Reaxys. https://www.elsevier.com/en-gb/solutions/reaxys

1. Reaxys – The Foundation for Chemistry Research
Michael Maier, Marcus Stamm – Nice, 08 April 2019

2. Reaxys Overview

3. |3
We have a long history in providing chemistry information
and driving new developments
1817: First edition of
Gmelin Handbook
1881: First
edition of
Beilstein
Handbook
1988: First
substance
loaded into
Beilstein
database
2009: Reaxys
launched
1989: Beilstein
and Gmelin
database go
online
2013/2014:
Complete overhaul
of Reaxys and
content expansion
including RMC
2017: New
Reaxys
Medicinal
Chemistry
(RMC) module
2016: New
Reaxys
launched

4. |4
The core of our philosophy: Reaxys aims to deliver
immediate access to information
… Reaxys aims to deliver relevant
answers on the spot:
• References ranked by relevance
• Reactions with experimental details
• Substances with extensive properties
Instead of delivering lists of
references that may be relevant to a
query…
?
?
?
?
Focus on using information, not searching for information

5. |5
Our Chemistry solution - Reaxys and Reaxys Medicinal
Chemistry - comprises 6 core databases
5
Bibliographic
Database
>59 million records
(from ~16,000 journal
titles plus records from
key patent
organizations)
Substance
Database
>146 million
substances (total
integrated content)
~ 118 million
substances
(unique)
Chemical
Reaction
Database
>49 million single- and
multi-step reactions
Property
Database
> 500 million
experimental properties
in > 400 fields
in > 130 subject areas
Bioactivity
Database
>37 million experimental
bioactivity data points
Target
Database
12.700 targets incl.
species information

6. Data extraction

7. |7
Manual data extraction
Reaxys covers most of the chemical space by manual data extraction
Reaxys manually extracts data from 421 journals and 7 patent offices.
To reduce overhead only relevant articles are sent to manual data extraction.
Relevancy of documents is determined by tools using machine learning, trained
for each content source individually.
110 k journal articles and 50 k patents are processed manually each year

8. |8
Automatic data extraction
Reaxys covers the chemical space and adjacent areas by automatic data extraction
Reaxys automatically extracts data from 15 k journals and 2 patent offices.
Substances and Reaxys Keywords are extracted by the automatic process.
2.2 mio journal articles, 150 k conference papers and 80 k patents are
processed automatically each year.
Extraction of substances and keywords is done based on relevancy,
determined for each entity in a document
Automatic identification of relevant chemical compounds from patents,
Akhondi, S. et al., Database, 2019, p. 1-14, doi: 10.1093/database/baz001

9. Quick search

10. Quick Search in Reaxys
Searches by text, structures or combinations of both possible
Natural language
Google-like input
Chemical Structures

11. Quick search identifies the expected search context
Reaxys contains several different types of databases that are searchable
Get intended answers directly, no pre-selection of a search context required
Documents Substances Reactions

12. Quick search translates user queries into search
queries
Quick search translates a user query into a technical search query for Reaxys
Users can create automatically complex searches
without detailed knowledge of the database

13. Quick search offers smart search options &
alternatives
Substance name search
Keyword search
Get intended answers as well as useful search alternatives

14. Quick search supports different types of patent
numbers
Flexible search for patent numbers
Patent number in the database: WO2013/10003
Other search possibilities
WO201310003A1
WO201310003 (A1)
WO 2013 10003
WO2013/10003
WO 2013/010003 A
WO201310003
Automated normalization of user query so that results are found in the database

15. Outlook

16. |16
Three strategic themes guide our roadmap to further
enhance our chemistry solution
“Chemistry
Ecosystem”
Support and build an
interconnected
“Chemistry Ecosystem”
enabling seamless
workflow solutions for
our customers: from
data integration and
search to analytics,
export and
data sharing
“Advanced
Analytics”
Maximize value of
experimental data
collections by building
and enabling
predictive modelling
applications
to gain new insights
“Segment
Solutions”
Provide access to all
relevant and reliable
content, concepts and
tools for a specific use
case and segment

17. Thank you very much for listening…