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Prevention
esp ROI and economic issues
Prevention – for own sake and to control
cost (cost / case v total no of cases)
• case is strong
• So why haven’t we done in it in the NHS?
• lack of incentives
• complexity of evidence
• lack of specificity especially on prevention
with long term
• confidence in economic modelling?
• requires culture change, which takes time
Prevention
• being able to take calculated risks
• time horizons
• multiple (often conflicting) objectives
• between sectors
• efficiency / inequalities / equity
• Cost-effectiveness and efficiency are not
the same as cost-cutting / cost savings
Prevention
• will it release cash in the short term? Or medium to
long term - highly uncertain
• Even when highly cost effective (most of the public
health interventions that have been analysed are
highly cost-effective)
• SAVE vs or slow rate of growth
• Wider approach (cost-benefit) recognising return on
investment techniques is to be welcomed
• discounting.
Even if its cost effective – ie net cost
• Crowd out downstream interventions
• Change the net social good of investment
• Factoring in downstream investments
often not done – reducing future burden
from heart failure.
Prevention and ROI
Take obesity as an example
• Do you need to win an argument about evidence, or is
it about cash, or is it about hearts and minds
• At what point do you intervene – bariatric surgery to
structural policy interventions
• Evidence re “community focused weight management”
– poor
• McKinsey report – NB perhaps some hidden agendas
re what they did / didn’t emphasise (their other
clients?)
• Find the primary studies. Appraise them. Contextualise
them
• Population impact– scale is important. Bariatric vs
sugar tax?
http://www.mckinsey.com/Insights/Economic_Studies/How_the_world_could_better_fight
_obesity
Take obesity as an example
• individual approach to effecting change at individual level
versus population wide policies affecting whole pops -
sugar tax, active travel, etc
• Clinical effectiveness at individual level,
• population impact and questions of economics
• cost to implement (cost to who),
• return (to who),
• time frame and horizon by which you need to see
results.
Take obesity as an example
• ROI tools – NICE. Challenge the
assumptions – do they work for you?
• Appendix T is where all the interesting
details hang out.
• Weight loss and lifestyle as a means of
preventing conversion from risk status
(obese) to disease (eg diabetes), and delay
of down the line complications of that
disease
Weightwatchers 1000 to 10
Dr Carl Heneghan
Small probability of attaining
normal body weight vs impact of
5% loss, or 10%
Population impact of weight
management
• 60% obese – 300k
• £300k spend on T2. 730 people a year
complete. 0.24% of at risk pop.
• If 100% success rate – 240 years to
“address obesity”
• Of our 730, 20% loose 5% of weight at 12w
• Slim chance of keeping off at 12m
• 142 “successes” in pop of 300k
https://gregfellpublichealth.wordpress.com/2018/10/30/population-impact-of-weight-
management-services/
Oceans and teaspoons – diabetes
prevention
• DPP trial.
– NNT = 7 at 5yrs
– Is it THAT effective in real life?
– SSHaRR model. Sheffield paramaters - £1.7k / 480
people / 120 benefit clinically, 25 cases of DM avided
out to 5y. NHS saves £192k not net of intervention
costs
• Philly sugar tax
– £60k to implement in pop of 0.5m
– 700 cases of DM avoided (10y)
– £40m (10y) saved
https://gregfellpublichealth.wordpress.com/2016/11/28/preventing-diabetes-comparing-
service-to-policy-based-approaches-on-emptying-an-ocean-with-a-teaspoon/
Others have written lots on tools
http://www.kingsfund.org.uk/publications/ex
ploring-system-wide-costs-falls-older-
people-torbay
Matrix
Prioritising Investment in Preventative
Health
http://help.matrixknowledge.com/file.axd
?file=HE_final_report.pdf
NICE
Teenage pregnancy, tobacco, obesity, activity
http://www.nice.org.uk/advice/lgb10
Owen et al
http://jpubhealth.oxfordjournals.org/content
/34/1/37
OECD
http://www.euro.who.int/en/about-us/partners/observatory/publications/policy-briefs-
and-summaries/promoting-health,-preventing-disease-is-there-an-economic-case
Even WHO are at it
http://www.euro.who.int/__data/assets/pdf_
file/0009/278073/Case-Investing-Public-
Health.pdf?ua=1
Kings Fund – pretty infographics
and good intelligence.
www.kingsfund.org.uk/publichealth or
www.local.gov.uk/health
NICE ROI Tools
https://www.nice.org.uk/About/What-we-
do/Into-practice/Return-on-investment-
tools
Economic tools to aid decision
making
July 2015
PHE Return on Investment Tools
http://www.yhpho.org.uk/default.aspx?RID
=194888
Tools included in the review
24
Tackling obesity Reducing smoking Reducing alcohol drinking
 NICE ROI – Physical Activity Tool
 NSMC - Behaviour Change Value
for Money Tool – Obesity
 NICE PH 41 Walking and Cycling –
Costing Template
 Weight Management Economic
Assessment Tool
 Health Economic Assessment Tool
(HEAT)
 Sport England Model for
Estimating the Outcomes and
Values in the Economics of Sport
(MOVES)
 NICE ROI – Tobacco Tool
 NICE - Brief interventions and
referral for smoking cessation.
 NICE - Varenicline for smoking
cessation
 NICE - Workplace interventions to
promote smoking cessation
 NSMC- Behaviour Change Value
for Money Tool – Tobacco
 Return on Investment calculator,
BTS
 NICE ROI – Alcohol Tool
 NSMC- Behaviour Change Value
for Money Tool - Alcohol
 Services for the identification and
treatment of hazardous drinking,
… - Commissioning and
benchmarking tool
 PHE Alcohol Ready Reckoner
 Alcohol System Model, NHS East
of England
Ensuring the best start in life Reducing dementia risk NHS Health Checks
 NICE ROI Children and Young
People
 NSMC- Behaviour Change Value
for Money Tool - Breastfeeding
 ---  Health Checks Ready Reckoner
General tools
 Health England Leading Prioritisation (H.E.L.P.) online tool
 Greater Manchester Cost Benefit Analysis tool
 Socio-Technical Allocation of Resources tool (STAR)
 Informing Investment to reduce health Inequalities (III)
Determinants
http://www.instituteofhealthequity.org/projects/understanding-the-economics-of-
investments-in-the-social-determinants-of-health
• YPHO
– http://www.yhpho.org.uk/resource/view.aspx?RID=195885
– helpful stuff bringing together many and a range of tools
that bring forward a focus on "investing in prevention"
• The LGA doc is all a bit motherhood and apple pie.
The links at the end of it are useful
– http://www.local.gov.uk/documents/10180/11493/Money+w
ell+spent+-
+Assessing+the+cost+effectiveness+and+return+on+inves
tment+of+public+service+interventions/25c68e94-ff2c-
4938-a41c-32853b4d4a9d
• This ppt very helpfully sets out the NICE approach to
return on investment
– http://www.lho.org.uk/Download/Public/18359/1/140129%2
0London%20K&I%20network%20-%20Kay%20Nolan%20-
%20NICE%20return%20on%20investment%20tools.ppt
QALY league Tables – use them at
your peril
Questions to ask
• was the time horizon appropriate.
• Was the comparator appropriate – best supportive
care, placebo, nothing, current management
• Was costing structure appropriate?
• Was the end point / outcome measured
appropriate….clinically meaningful and
sensible……surrogate endpoints for short trials.
Back to contents
• the health warning is thus.....
• all these things are done at different points in time, with
different methods, and often different comparators
• so if trying to do relative comparison to say x is more
cost effective than y so we should do more of x..... is
fraught with this sort of danger....
• and then without knowing the detail of how the cost
effectiveness of x was derived...... whether you use
method (a) to value quality of life, of cost etc..... or
method (b) can make a massive difference.....to the
absolute value of the cost effectiveness metric .....
• difficult stuff
Whatever way you cut it, the basic
economic principles still apply
• You can use and abuse the principles at your
leisure
• Do so with caution – credibility
• However – remember others will also –
“street fighting with evidence”.
• Or they may just ignore evidence – it might
not be a debate that’s about evidence – it
might be about belief and ideology.
• Use evidence wisely to crowd out less cost
effective investments – net social gain.
why we might invest in pre school and
primary school and NOT NHS??
http://www.huffingtonpost.com/2015/04/20/
anti-poverty-
programs_n_7087622.html?utm_hp_ref=w
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3 prevention

  • 1. Prevention esp ROI and economic issues
  • 2. Prevention – for own sake and to control cost (cost / case v total no of cases) • case is strong • So why haven’t we done in it in the NHS? • lack of incentives • complexity of evidence • lack of specificity especially on prevention with long term • confidence in economic modelling? • requires culture change, which takes time
  • 3. Prevention • being able to take calculated risks • time horizons • multiple (often conflicting) objectives • between sectors • efficiency / inequalities / equity • Cost-effectiveness and efficiency are not the same as cost-cutting / cost savings
  • 4. Prevention • will it release cash in the short term? Or medium to long term - highly uncertain • Even when highly cost effective (most of the public health interventions that have been analysed are highly cost-effective) • SAVE vs or slow rate of growth • Wider approach (cost-benefit) recognising return on investment techniques is to be welcomed • discounting.
  • 5. Even if its cost effective – ie net cost • Crowd out downstream interventions • Change the net social good of investment • Factoring in downstream investments often not done – reducing future burden from heart failure.
  • 7. Take obesity as an example • Do you need to win an argument about evidence, or is it about cash, or is it about hearts and minds • At what point do you intervene – bariatric surgery to structural policy interventions • Evidence re “community focused weight management” – poor • McKinsey report – NB perhaps some hidden agendas re what they did / didn’t emphasise (their other clients?) • Find the primary studies. Appraise them. Contextualise them • Population impact– scale is important. Bariatric vs sugar tax? http://www.mckinsey.com/Insights/Economic_Studies/How_the_world_could_better_fight _obesity
  • 8. Take obesity as an example • individual approach to effecting change at individual level versus population wide policies affecting whole pops - sugar tax, active travel, etc • Clinical effectiveness at individual level, • population impact and questions of economics • cost to implement (cost to who), • return (to who), • time frame and horizon by which you need to see results.
  • 9. Take obesity as an example • ROI tools – NICE. Challenge the assumptions – do they work for you? • Appendix T is where all the interesting details hang out. • Weight loss and lifestyle as a means of preventing conversion from risk status (obese) to disease (eg diabetes), and delay of down the line complications of that disease
  • 10. Weightwatchers 1000 to 10 Dr Carl Heneghan
  • 11. Small probability of attaining normal body weight vs impact of 5% loss, or 10%
  • 12. Population impact of weight management • 60% obese – 300k • £300k spend on T2. 730 people a year complete. 0.24% of at risk pop. • If 100% success rate – 240 years to “address obesity” • Of our 730, 20% loose 5% of weight at 12w • Slim chance of keeping off at 12m • 142 “successes” in pop of 300k https://gregfellpublichealth.wordpress.com/2018/10/30/population-impact-of-weight- management-services/
  • 13. Oceans and teaspoons – diabetes prevention • DPP trial. – NNT = 7 at 5yrs – Is it THAT effective in real life? – SSHaRR model. Sheffield paramaters - £1.7k / 480 people / 120 benefit clinically, 25 cases of DM avided out to 5y. NHS saves £192k not net of intervention costs • Philly sugar tax – £60k to implement in pop of 0.5m – 700 cases of DM avoided (10y) – £40m (10y) saved https://gregfellpublichealth.wordpress.com/2016/11/28/preventing-diabetes-comparing- service-to-policy-based-approaches-on-emptying-an-ocean-with-a-teaspoon/
  • 14. Others have written lots on tools http://www.kingsfund.org.uk/publications/ex ploring-system-wide-costs-falls-older- people-torbay
  • 15. Matrix Prioritising Investment in Preventative Health http://help.matrixknowledge.com/file.axd ?file=HE_final_report.pdf
  • 16.
  • 17. NICE Teenage pregnancy, tobacco, obesity, activity http://www.nice.org.uk/advice/lgb10
  • 20. Even WHO are at it http://www.euro.who.int/__data/assets/pdf_ file/0009/278073/Case-Investing-Public- Health.pdf?ua=1
  • 21. Kings Fund – pretty infographics and good intelligence. www.kingsfund.org.uk/publichealth or www.local.gov.uk/health
  • 23. Economic tools to aid decision making July 2015 PHE Return on Investment Tools http://www.yhpho.org.uk/default.aspx?RID =194888
  • 24. Tools included in the review 24 Tackling obesity Reducing smoking Reducing alcohol drinking  NICE ROI – Physical Activity Tool  NSMC - Behaviour Change Value for Money Tool – Obesity  NICE PH 41 Walking and Cycling – Costing Template  Weight Management Economic Assessment Tool  Health Economic Assessment Tool (HEAT)  Sport England Model for Estimating the Outcomes and Values in the Economics of Sport (MOVES)  NICE ROI – Tobacco Tool  NICE - Brief interventions and referral for smoking cessation.  NICE - Varenicline for smoking cessation  NICE - Workplace interventions to promote smoking cessation  NSMC- Behaviour Change Value for Money Tool – Tobacco  Return on Investment calculator, BTS  NICE ROI – Alcohol Tool  NSMC- Behaviour Change Value for Money Tool - Alcohol  Services for the identification and treatment of hazardous drinking, … - Commissioning and benchmarking tool  PHE Alcohol Ready Reckoner  Alcohol System Model, NHS East of England Ensuring the best start in life Reducing dementia risk NHS Health Checks  NICE ROI Children and Young People  NSMC- Behaviour Change Value for Money Tool - Breastfeeding  ---  Health Checks Ready Reckoner General tools  Health England Leading Prioritisation (H.E.L.P.) online tool  Greater Manchester Cost Benefit Analysis tool  Socio-Technical Allocation of Resources tool (STAR)  Informing Investment to reduce health Inequalities (III)
  • 26. • YPHO – http://www.yhpho.org.uk/resource/view.aspx?RID=195885 – helpful stuff bringing together many and a range of tools that bring forward a focus on "investing in prevention" • The LGA doc is all a bit motherhood and apple pie. The links at the end of it are useful – http://www.local.gov.uk/documents/10180/11493/Money+w ell+spent+- +Assessing+the+cost+effectiveness+and+return+on+inves tment+of+public+service+interventions/25c68e94-ff2c- 4938-a41c-32853b4d4a9d • This ppt very helpfully sets out the NICE approach to return on investment – http://www.lho.org.uk/Download/Public/18359/1/140129%2 0London%20K&I%20network%20-%20Kay%20Nolan%20- %20NICE%20return%20on%20investment%20tools.ppt
  • 27. QALY league Tables – use them at your peril Questions to ask • was the time horizon appropriate. • Was the comparator appropriate – best supportive care, placebo, nothing, current management • Was costing structure appropriate? • Was the end point / outcome measured appropriate….clinically meaningful and sensible……surrogate endpoints for short trials. Back to contents
  • 28. • the health warning is thus..... • all these things are done at different points in time, with different methods, and often different comparators • so if trying to do relative comparison to say x is more cost effective than y so we should do more of x..... is fraught with this sort of danger.... • and then without knowing the detail of how the cost effectiveness of x was derived...... whether you use method (a) to value quality of life, of cost etc..... or method (b) can make a massive difference.....to the absolute value of the cost effectiveness metric ..... • difficult stuff
  • 29. Whatever way you cut it, the basic economic principles still apply • You can use and abuse the principles at your leisure • Do so with caution – credibility • However – remember others will also – “street fighting with evidence”. • Or they may just ignore evidence – it might not be a debate that’s about evidence – it might be about belief and ideology. • Use evidence wisely to crowd out less cost effective investments – net social gain.
  • 30. why we might invest in pre school and primary school and NOT NHS?? http://www.huffingtonpost.com/2015/04/20/ anti-poverty- programs_n_7087622.html?utm_hp_ref=w hats-working