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DayOne Experts - Healthcare Innovation - reinvented

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It’s an expensive und exhausting run against time: It takes approximately 2,3 billion Dollars and 12 years to bring a drug to the market. This leaves only 8 years until the expiration of the patent to bring back sufficient return on investments. So far, this has worked out well for the industry but the run is getting steeper every year: on the one hand, it becomes increasingly complex and expensive to develop new drugs, on the other hand prizes are under scrutiny. Hence, the industry is sitting on a time bomb, as the day will come when the returns will not cover the investments anymore and the innovation pipeline will dry out because bringing new drugs to the market does no longer offer any financial incentives.

What can be done about this scenario? Eventually (and hopefully), these projections prove wrong as there is still a lot to be gained by efficiency improvement through digitalizing all along the value chain – after all healthcare still is one of the least digitalized industries. Will this be enough – or do we have to reinvent healthcare innovation in a radical new way?

This DayOne Experts Event showcased some game changing ideas and discussed their feasibility and impact with an expert panel and the audience. These slides are just the intro to this Event.

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DayOne Experts - Healthcare Innovation - reinvented

  1. 1. DayOne Core Team Experts from across industry and stakeholders Michael Rebhan, Novartis Peter Groenen, Idorsia Alain Bindels, Roche Frank Kumli, Ernst & Young Torsten Schwede, University of Basel and Swiss Institute of Bioinformatics Andreas Wicki, University Hospital Basel Erik Schkommodau, University of Applied Science and Arts Northwestern Switzerland Christian Bosshard, CSEM Laurenz Baltzer, KARGER Bram Stieltjes, University Hospital Basel André Moeri, Medgate Bhupinder Bhullar, Consultant Douglas Haggstrom, Consultant Thomas Brenzikofer, BaselArea.swiss Fabian Streiff, Department of Economic, Social and Environmental Affairs of the Canton of Basel-Stadt DayOne Experts – 7.5.2019 DayOne Experts: Healthcare Innovation – reinvented
  2. 2. Thomas Brenzikofer, BaselArea.swiss, Co-Founder DayOne DayOne Creating a world-leading hub for healthcare innovation in precision medicine and digital health
  3. 3. the leading hub for healthcare innovation in precision medicine
  4. 4. A growing community of healthcare innovators 1500 professionals, entrepreneurs, researchers across all disciplines
  5. 5. DayOne Core Team Experts from across industry and stakeholders Michael Rebhan, Novartis Peter Groenen, Idorsia Alain Bindels, Roche Torsten Schwede, University of Basel and Swiss Institute of Bioinformatics Christian Elias Schneider, University of Basel Andreas Wicki, Bram Stieltjes University Hospital Basel Nicole Probst-Hensch, Melissa Penny, Swiss TPH Erik Schkommodau, Enkelejda Miho, University of Applied Science and Arts FHNW Christian Bosshard, CSEM Laurenz Baltzer, KARGER André Moeri, Medgate Management Team: Bhupinder Bhullar, Douglas Haggstrom, Viktor Bullain, Bejal Joshi, Consultants Frank Kumli, Fabian Streiff, Thomas Brenzikofer, BaselArea.swiss
  6. 6. DayOne Partners Public and Industry INITIATED AND OPERATED BY IN CLOSE COLLABORATION WITH KNOWLEDGE PARTNERS SUPPORTING PARTNERS
  7. 7. DayOne Mission Create a world leading hub for healthcare innovation, built on the strength of the Basel region respected for its impact facilitating collaboration across disciplines and industries with a focus on precision medicine – the convergence of diagnostics, treatment and digital health
  8. 8. Implement Innovate Improve Invent Test Innovation hub as a neutral Platform Different activities reinforcing each other
  9. 9. DayOne Core Team Experts from across industry and stakeholders Michael Rebhan, Novartis Peter Groenen, Idorsia Alain Bindels, Roche Frank Kumli, Ernst & Young Torsten Schwede, University of Basel and Swiss Institute of Bioinformatics Andreas Wicki, University Hospital Basel Erik Schkommodau, University of Applied Science and Arts Northwestern Switzerland Christian Bosshard, CSEM Laurenz Baltzer, KARGER Bram Stieltjes, University Hospital Basel André Moeri, Medgate Bhupinder Bhullar, Consultant Douglas Haggstrom, Consultant Thomas Brenzikofer, BaselArea.swiss Fabian Streiff, Department of Economic, Social and Environmental Affairs of the Canton of Basel-Stadt DayOne Experts – 7.5.2019 DayOne Experts: Healthcare Innovation – reinvented
  10. 10. An expiring innovation model Source: https://www.technology<eview.com/s/609647/google-has-released-an-ai-tool-that-makes-sense-of-your-genome/© Return on Investment Time
  11. 11. An expiring innovation model Source: https://www.technology<eview.com/s/609647/google-has-released-an-ai-tool-that-makes-sense-of-your-genome/© Return on Investment Time 2020
  12. 12. An expiring innovation model Source: https://www.technology<eview.com/s/609647/google-has-released-an-ai-tool-that-makes-sense-of-your-genome/© Return on Investment Time 2030
  13. 13. What’s at stake? A unique desity of life sciences companies 1 3
  14. 14. The old paradigm Innovation as we know it Invent Test Implement Innovate Level of development Resources Valley of death
  15. 15. Basics Three types of innovation Efficiency  more of the same for less Incremental  doing the same, but better Change  finding new ways of doing things Clayton Christensen
  16. 16. Basics Three types of innovation Efficiency  more of the same for less Incremental  doing the same, but better Change  finding new ways of doing things Clayton Christensen
  17. 17. Basics Three types of innovation Efficiency  more of the same for less Incremental  doing the same, but better Change  finding new ways of doing things Clayton Christensen
  18. 18. Change Drivers Breakthrough Technology: Digital Ecosystem Adaption
  19. 19. Change Disruption & Adaption Breakthrough Technology: Digital Ecosystem Adaption
  20. 20. The new paradigm Innovation as we don‘t know it: patient centric, agile, collaborative initial failed product reservoir redefined patient population patient in the middle product proposal product prototype revised product repositioned product medicalneed problem statement refined product proposal product experience redefine product testinvent implement innovate
  21. 21. Implement Innovate Improve Invent Test Ecosystem Innovation Adressing the whole value chain
  22. 22. DayOne Core Team Experts from across industry and stakeholders Michael Rebhan, Novartis Peter Groenen, Idorsia Alain Bindels, Roche Frank Kumli, Ernst & Young Torsten Schwede, University of Basel and Swiss Institute of Bioinformatics Andreas Wicki, University Hospital Basel Erik Schkommodau, University of Applied Science and Arts Northwestern Switzerland Christian Bosshard, CSEM Laurenz Baltzer, KARGER Bram Stieltjes, University Hospital Basel André Moeri, Medgate Bhupinder Bhullar, Consultant Douglas Haggstrom, Consultant Thomas Brenzikofer, BaselArea.swiss Fabian Streiff, Department of Economic, Social and Environmental Affairs of the Canton of Basel-Stadt DayOne Experts – 7.5.2019 DayOne Experts: Healthcare Innovation – reinvented
  23. 23. DayOne Core Team Experts from across industry and stakeholders Michael Rebhan, Novartis Peter Groenen, Idorsia Alain Bindels, Roche Frank Kumli, Ernst & Young Torsten Schwede, University of Basel and Swiss Institute of Bioinformatics Andreas Wicki, University Hospital Basel Erik Schkommodau, University of Applied Science and Arts Northwestern Switzerland Christian Bosshard, CSEM Laurenz Baltzer, KARGER Bram Stieltjes, University Hospital Basel André Moeri, Medgate Bhupinder Bhullar, Consultant Douglas Haggstrom, Consultant Thomas Brenzikofer, BaselArea.swiss Fabian Streiff, Department of Economic, Social and Environmental Affairs of the Canton of Basel-Stadt 18:15 Welcome and introduction: Thomas Brenzkofer 18:30 Input Speeches and Panel Discussion: Peter Groenen, Idorsia – industry perspective Melissa Penny, Swiss TPH – gobal health perspective Noé Brasier, USB – hospital as innovation hub Giovanni Nisato, Health Hacking Lab – community approach Martin Etzrodt, Akasha Foundation – collaborative research Paul Kohlhaas, Molecule – reengineering patents 20:00 closing remarks followed by networking apero
  24. 24. Next Events next generation digital trials – 25. June dayOne acceleration demo day – 25. June dayOne conference – 9. September new approaches in patient centricity – October/November future business models – December
  25. 25. thomas.brenzikofer@baselarea.swiss CONTACT the leading hub for healthcare innovation in precision medicine
  26. 26. www.dayone.swiss #dayonebasel LinkedIn Groups: „DayOne – Innovation Hub for Precision Medicine“

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