The profile gives broad outline of process and market scenario on Glutraldehyde

1. GLUTARALDEHYDE
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PRODUCT PROFILE ON GLUTARALDEHYDE
1. PRODUCT ANALYSIS ..............................................................................................................................3
1.1. General details.......................................................................................................................................3
1.2. Application........................................................................................................................................4
2. PROCESS OUTLINE AND RAW MATERIAL DETAILS................................................................................5
2.1. Process outline..................................................................................................................................5
2.2. Diels-Alder reaction of Acrolein with methyl vinyl ether. ................................................................5
Raw material requirements ......................................................................................................................5
2.3. Cost structure..................................................................................... Error! Bookmark not defined.
Annual requirement of Raw material and Utilities.................................... Error! Bookmark not defined.
3. TRADE ANALYSIS ...................................................................................................................................6
3.1. Import data .......................................................................................................................................6
3.2. Export data........................................................................................................................................6
4. GLOBAL DEMAND - SUPPLY SCEANRIO.................................................................................................7
4.1. Global market - Period 2020.............................................................................................................7
4.2. Projected Global market - Period 2025 ............................................................................................7
4.3. Global supply scenario......................................................................................................................7
4.4. Registered trade names....................................................................................................................7
4.5. Application sectorwise demand........................................................................................................8
4.5.1. Demand for Glutaraldehyde in health care sector .................... Error! Bookmark not defined.
4.5.2. Demand for Glutaraldehyde in oil field sector........................... Error! Bookmark not defined.
4.6. Regionwise demand pattern.............................................................. Error! Bookmark not defined.
4.7. Demand drivers.................................................................................. Error! Bookmark not defined.
Advantages of Glutaraldehyde .................................................................. Error! Bookmark not defined.
Environmental Profile ................................................................................ Error! Bookmark not defined.
4.8. Impact on COVID-19 on biocide Glutaraldehyde............................... Error! Bookmark not defined.
Positive growth rate in demand................................................................. Error! Bookmark not defined.
Factors restrain the market growth........................................................... Error! Bookmark not defined.

2. GLUTARALDEHYDE
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5. PRICE TRENDS .......................................................................................................................................9
5.1. Historical and current CIF price trends – Glutaraldehyde 50% solution...........................................9
5.1.1. America.........................................................................................................................................9
5.1.2. Europe...........................................................................................................................................9
5.1.3. China ...........................................................................................................................................10
FDA CLEARED GLUTARALDEHYDE CONTAINING DISINFECTANTS FOR MEDICAL DEVICE... Error! Bookmark
not defined.
COMPARISON OF THE CHARACTERISTICS OF SELECTED CHEMICALS USED AS HIGH-LEVEL DISINFECTANTS
OR CHEMICAL STERILANTS............................................................................. Error! Bookmark not defined.

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1. PRODUCT ANALYSIS
1.1. General details
Chemical formula : C5H8O2
Appearance : Originally it is colourless crystals
The water solution is colourless oily liquid
Odour : Sharp pungent odour
CAS No. : 111-30-8
Alternate name : Pentanediol
Chemical structure : OHC-CH2-CH2-CH2-CHO
Molecular Mass : 100.117 g/mol
Boiling Point : 187-189ºC
Melting Point : -14 deg C
Solubility : Miscible in water 51.3 g/ml;
Soluble in Ethanol, Benzene, and Ether.
Stability
The anhydrous form of glutaraldehyde is unstable, and therefore, it is only available commercially as a
solution. Dilute glutaraldehyde solutions (1–3.5%) are typically used for disinfecting, but they tend to
polymerize with time, resulting in a solution containing limited aldehyde radicals and consequently
reduced antibacterial function. Glutaraldehyde solutions must, therefore, be prepared fresh on a regular
basis.
Increasing temperature will destabilize the product. Stable under acidic to neutral conditions.
Stable in light; It oxidizes in the presence of air.

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1.2. Application
 Disinfectant for surgical instruments that cannot be heat sterilized
 A cross-linking and tanning agent
 A biocide in metalworking fluids and in oil and gas pipelines
 An antimicrobial in water-treatment systems
 A slimicide in paper manufacturing
 A preservative in cosmetics
 A disinfectant in animal housing
 A tissue fixative in histology and pathology labs
 A hardening agent in the development of X-rays
 In embalming solutions
 In the preparation of grafts and bioprostheses
 In various clinical applications
 A biocide in textile, paint, poultry industry
 Other miscellaneous use include filler, intermediate, processing aid etc

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2. PROCESS OUTLINE AND RAW MATERIAL DETAILS
2.1. Process outline
Glutardialdehyde is produced industrially by the following two methods
 Gas-phase oxidation of cyclopentene
 Diels-Alder reaction of Acrolein with methyl vinyl ether.
Both reactions utilize a multistage extraction with water to recover the glutaraldehyde.
2.2. Diels-Alder reaction of Acrolein with methyl vinyl ether.
In the Diels-Alder reaction, the reaction of acrolein and methyl vinyl ether in a 1:1 ratio results in 2-
methoxy-3,4-dihydro-2H-pyran (MDP, CAS No. 4454-05-1), which undergoes acidic hydrolysis in presence
of water and acid to yield glutaraldehyde and methanol at temperature 95 to 110 deg C for 2 to 3 hrs.
The crude hydrolysis product is distilled to produce a methanol overheads stream, a by-product of the
reaction that is itself suitable for recycling and use in other industrial processes, and a tails product
containing glutaraldehyde in water.
Raw material requirements
Basis: One kg of glutaraldehyde crystals (100% product)
Raw materials Requirements in kg
Acrolein 0.5
Methyl vinyl ether 0.5
Other miscellaneous products including catalyst,
DM water
-
2-methoxy-3,4-dihydro-2H-pyran is obtained as a intermediate product which upon acid hydrolysis
yields Glutaraldehyde solution of various concentrations.

6. GLUTARALDEHYDE
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3. TRADE ANALYSIS
3.1. Import data
Annual import quantity per annum – Period April 2019 to March 2020
(Product acyclic aldehydes including Glutaraldehyde (excluding formaldehyde and acetaldehyde)
Regions Import quantity
in tones per annum
North America 26000
European regions 115000
Asia Pacific region including
China
49200
3.2. Export data
Annual export quantity per annum – Period April 2019 to March 2020
(Product acyclic aldehydes including Glutaraldehyde (excluding formaldehyde and acetaldehyde)
Regions Export quantity
in tones per annum
Europe 135000
USA 55000
China 34000

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4. GLOBAL DEMAND - SUPPLY SCEANRIO
4.1. Global market - Period 2020
Global market for Glutaraldehyde – Period 2020 USD 700 million
Global production of Glutaraldehyde – Period 2020 0.30 million tonnes
4.2. Projected Global market - Period 2025
Projected Global market USD 845 million
Projected Global production 0.34 million tonnes
CAGR in market value 3.8%
4.3. Global supply scenario
Glutaraldehyde is available mostly at 45% or 50% solution
Estimated Global production of Glutaraldehyde solution (50%)
 BASF
 Dow Chemicals
 Union Carbide
 Finoric
 Laohekou Jinghong Chemical
 AppliChem
 AerChem
 JSL Chemical
 Electron Microscopy Sciences
 Hubei Xinjing New Material
4.4. Registered trade names
 Protectol GA 50 (BASF)
 Myacide GA 50, 45, 25, 15 (BASF)
 Ucarcide (Union Carbide)
 Sporicidin
 Hospex
 Omnicide
 Ucardine;
 Nuosept 95;
 Cidex
 Sonacide;
 Coldcide-25
 Glutaral

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4.5. Application sectorwise demand
Global demand for Glutaraldehyde 0.3 million tonnes
Global market for Glutaraldehyde USD 700 million

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5. PRICE TRENDS
5.1. Historical and current CIF price trends – Glutaraldehyde 50% solution
5.1.1. America
5.1.2. Europe
2.3300
2.2670
2.3784
2.2449 2.3207
2.8611
2.5277
2.6149
2.8870 2.8053
2.5802
0.0000
0.5000
1.0000
1.5000
2.0000
2.5000
3.0000
3.5000 CIF RICE IN USD PER KG
3.0000
3.0000
2.9391
2.9555 2.9658
2.8662 2.8662 2.8458
2.7500
2.8000
2.8500
2.9000
2.9500
3.0000
3.0500
CIF PRICE IN USD PER KG

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5.1.3. China
3.0000
2.0900
1.7500 1.7000
1.8500
2.8465
2.7000 2.6000
1.7500
3.0967
1.6800
1.8400
0.0000
0.5000
1.0000
1.5000
2.0000
2.5000
3.0000
3.5000
CIF price in USD per kg

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