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Prof. G.S.Patnaik
MBBS;MS (ortho) FAOI(USA),FACS, PhD
Consultant Orthopedic Surgeon
Musculoskeletal
Manifestations of Diabetes Mellitus:
Orthopedic and Rheumatologic afflictions in Diabetes
Mellitus A review
11/16/2020 www.drgspatnaik.com 2
Dibetes Mellitus
 Multi-system
disease
 Persistent
Hyperglycemia
 Acute and chronic
biochemical and
anatomical sequel
 Can affect the
connective tissue in
a variety of ways
11/16/2020 www.drgspatnaik.com 3
Diabetes Mellitus
 Variety of alterations
in Locomotor system
 Neuroarthropathy
 Hyperostosis
 Osteoporosis
 Cheiroarthropathy
 Limited joint mobility
 Muscular infarctions
11/16/2020 www.drgspatnaik.com 4
Musculoskeletal Manifestations
 Carpal tunnel
syndrome
 Diabetic stiff hands
syndrome
 Neuropathic joints
 Calcific tendinitis
 Complex Regional
pain syndrome
 Diabetic Muscle
Infarctions
11/16/2020 www.drgspatnaik.com 5
Carpal Tunnel Syndrome
 1/3rd of diabetic patient
 Prevalence increases
with duration of disease
 Diabetes induced
connective tissue
changes, including
sclerosis and collagen
degradation.
 Diagnosis based on
history and clinical
findings
 Burning,Paraesthesia or
sensory loss in median
nerve distribution
11/16/2020 www.drgspatnaik.com 6
Carpal Tunnel Syndrome
 EMG/nerve conduction
studies can confirm the
diagnosis
 Conservative treatments
include medications,
splints, change of
working environment
 Local Corticosteroid
injection
 If no significant relief
then surgery is an
option
 Safe surgery
11/16/2020 www.drgspatnaik.com 7
Adhesive capsulitis
 20% of diabetic cases
 Stiffened
glenohumeral joint
caused by thickening
and contraction of
joint capsule
 Shoulder stiffness,
decreased range of
movement and pain
 Abduction and
external rotation worst
affected
 Internal rotation is
affected least
11/16/2020 www.drgspatnaik.com 8
Frozen Shoulder
 Therapy is largely
conservative
 Mobilization of
shoulder joint
 Physical therapy
 Gentle stretching
and range of motion
exercises
 Analgesics
 Intra-articular
injection
11/16/2020 www.drgspatnaik.com 9
11/16/2020 www.drgspatnaik.com 10
Tenosynovitis
 Flexor Tenosynovitis
(trigger finger)
frequent complication
of diabetic hand
 Catching or locking
episodes
 Palpable nodule and
thickening along the
affected flexor tendon
sheath overlying
palmer aspect of MP
joint
11/16/2020 www.drgspatnaik.com 11
Tenosynovitis
 Primary treatment
include rest, ice,
compression,
elevation (RICE)
 Local Hydro
corticosteroids
Injection
 Surgery in chronic
conditions resistant to
medical conditions.
11/16/2020 www.drgspatnaik.com 12
Dupuytrens’s contracture
 Affects palmer
fascia
 Causes flexion
contractures of
fingers
 Usually the 4th finger
 1/3rd of diabetic
patients
 Local H.C. injections
 Surgical intervention
in severe cases
11/16/2020 www.drgspatnaik.com 13
Diabetic Osteoarthropathy
 Charcot’s or neuropathic
arthropathy is a
condition involving
destructive , lytic joint
changes
 Severe destructive form
of degenerative arthritis
 Most commonly affects
pedal bones
 Classical radiographical
findings
 CT and MRI scans
11/16/2020 www.drgspatnaik.com 14
Diabetic osteoarthropathy
Treatment
 Challenging
treatment
 Good Glycemic
control
 Splinting and
bracing to protect
foot from weight
bearing
 Debridement
 Amputation
11/16/2020 www.drgspatnaik.com 15
Conclusion
 D.M. associated with variety of musculo
-skeletal disorders
 Most commonly seen in Type 1 but Type
2 are not immune
 Clinicians should be aware to intervene
and provide best care for affected
patients
 Ask patients for symptoms rather than
wait for him to speak.
11/16/2020 www.drgspatnaik.com 16
Suggested Readings
www.drgspatnaik.com
11/16/2020 www.drgspatnaik.com 17
www.drgspatnaik.com drgspatnaik@gmail.com
11/16/2020 www.drgspatnaik.com 18
11/16/2020 www.drgspatnaik.com 19

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Musculoskeletal manifestations of diabetes mellitus

  • 1. Prof. G.S.Patnaik MBBS;MS (ortho) FAOI(USA),FACS, PhD Consultant Orthopedic Surgeon
  • 2. Musculoskeletal Manifestations of Diabetes Mellitus: Orthopedic and Rheumatologic afflictions in Diabetes Mellitus A review 11/16/2020 www.drgspatnaik.com 2
  • 3. Dibetes Mellitus  Multi-system disease  Persistent Hyperglycemia  Acute and chronic biochemical and anatomical sequel  Can affect the connective tissue in a variety of ways 11/16/2020 www.drgspatnaik.com 3
  • 4. Diabetes Mellitus  Variety of alterations in Locomotor system  Neuroarthropathy  Hyperostosis  Osteoporosis  Cheiroarthropathy  Limited joint mobility  Muscular infarctions 11/16/2020 www.drgspatnaik.com 4
  • 5. Musculoskeletal Manifestations  Carpal tunnel syndrome  Diabetic stiff hands syndrome  Neuropathic joints  Calcific tendinitis  Complex Regional pain syndrome  Diabetic Muscle Infarctions 11/16/2020 www.drgspatnaik.com 5
  • 6. Carpal Tunnel Syndrome  1/3rd of diabetic patient  Prevalence increases with duration of disease  Diabetes induced connective tissue changes, including sclerosis and collagen degradation.  Diagnosis based on history and clinical findings  Burning,Paraesthesia or sensory loss in median nerve distribution 11/16/2020 www.drgspatnaik.com 6
  • 7. Carpal Tunnel Syndrome  EMG/nerve conduction studies can confirm the diagnosis  Conservative treatments include medications, splints, change of working environment  Local Corticosteroid injection  If no significant relief then surgery is an option  Safe surgery 11/16/2020 www.drgspatnaik.com 7
  • 8. Adhesive capsulitis  20% of diabetic cases  Stiffened glenohumeral joint caused by thickening and contraction of joint capsule  Shoulder stiffness, decreased range of movement and pain  Abduction and external rotation worst affected  Internal rotation is affected least 11/16/2020 www.drgspatnaik.com 8
  • 9. Frozen Shoulder  Therapy is largely conservative  Mobilization of shoulder joint  Physical therapy  Gentle stretching and range of motion exercises  Analgesics  Intra-articular injection 11/16/2020 www.drgspatnaik.com 9
  • 11. Tenosynovitis  Flexor Tenosynovitis (trigger finger) frequent complication of diabetic hand  Catching or locking episodes  Palpable nodule and thickening along the affected flexor tendon sheath overlying palmer aspect of MP joint 11/16/2020 www.drgspatnaik.com 11
  • 12. Tenosynovitis  Primary treatment include rest, ice, compression, elevation (RICE)  Local Hydro corticosteroids Injection  Surgery in chronic conditions resistant to medical conditions. 11/16/2020 www.drgspatnaik.com 12
  • 13. Dupuytrens’s contracture  Affects palmer fascia  Causes flexion contractures of fingers  Usually the 4th finger  1/3rd of diabetic patients  Local H.C. injections  Surgical intervention in severe cases 11/16/2020 www.drgspatnaik.com 13
  • 14. Diabetic Osteoarthropathy  Charcot’s or neuropathic arthropathy is a condition involving destructive , lytic joint changes  Severe destructive form of degenerative arthritis  Most commonly affects pedal bones  Classical radiographical findings  CT and MRI scans 11/16/2020 www.drgspatnaik.com 14
  • 15. Diabetic osteoarthropathy Treatment  Challenging treatment  Good Glycemic control  Splinting and bracing to protect foot from weight bearing  Debridement  Amputation 11/16/2020 www.drgspatnaik.com 15
  • 16. Conclusion  D.M. associated with variety of musculo -skeletal disorders  Most commonly seen in Type 1 but Type 2 are not immune  Clinicians should be aware to intervene and provide best care for affected patients  Ask patients for symptoms rather than wait for him to speak. 11/16/2020 www.drgspatnaik.com 16