2. What is Pre-Eclampsia??
A PREGNANCY SPECIFIC SYNDROME
CHARACTERIZED BY VARIABLE DEGREES OF
PLACENTAL DYSFUNCTION AND A MATERNAL
RESPONSE FEATURING SYSTEMIC INFLAMMATION.
4. WHEN WE ARE CONSIDERING A CASE AS
NON SEVERE???
Cases with sustained rise of blood pressure of more than
140/90 mm Hg but less than 160 mm Hg systolic or 110 mm
Hg diastolic without significant protienuria (less than or
equal to 2+) and without any signs of end organ
injury/damage.
Headache, Seizures, Visual disturbance.
Epigastric pain, Liver enzymes.
Fetal growth.
Clotting.
Pre Eclampsia is a bad disease and the term mild is
discouraged.
Classified as NON SEVERE and SEVERE PRE ECLAMPSIA.
5. Management
OBJECTIVES:
To stabilize the HTN and to prevent its
progression to severe pre eclampsia.
To prevent complications.
To prevent eclampsia.
Delivery of healthy baby in optimal time.
Restoration of the health of the mother.
7. Management
Blood pressure:
Should be recorded more frequently in women at high risk of PE
Rapid increases warrant closer observation
Oedema:Rapidly increasing generalised, facial and/or periorbital oedema
requires further assessment.
New onset of PE is suspected laboratory investigations to track
progression:
Haemocrit values
Liver function tests
Renal tests
Coagulation screening
Urinanalysis
8. Management
Fetal monitoring:
Antepartum surveillance (CTG’s)
Symphyseal-fundal height measurements
Record of fetal movements
Ultrasonography:
Amniotic fluid index
Fetal growth
Biophysical profiles
Umbilical artery Doppler studies
Used to monitor fetal growth and to ascertain the most appropriate
and safest time for delivery
9. Management
If DBP settles, protienuria becomes insignificant then
she will be adviced to take rest, have her BP checked
regularly.
Report to the hospital if she develop significant
swelling or develops other symptoms of severe
pre-eclampsia.
10. Management
If there are any signs of fetal compromise, labour is
induced.
If there is no fetal compromise, and the pre-eclampsia
doesnot worsen, pregnancy could be continued for
another week.
11. Management
Expectant Management:
No evidence that hospital admission for Non severe PE
improves maternal or fetal outcomes
Admission to hospital is stressful, emotionally and
financially costly
Women with Non severe PE without significant
proteinuria may be treated as outpatient or admitted as
a ‘day case’ for assessment and evaluation
12. Management
Expectant Management:
Expectant management at home or hospital requires:
Reduced activity
Woman may be advised to stop working
May be advised to go on bed rest – although this is logical it
has not been proved to improve outcomes
Careful recording and daily checking of:
Fetal activity
Blood pressure
Urine protein
Any other signs and symptoms of PE
13. Management
The role is to:
Recognise pre-eclampsia early
Monitor the woman for evidence of disease
progression that would mandate either
delivery of more intensive fetal surveillance
14. Management
Hospital Management:
May be necessary for woman who:
Feel safer in hospital
Hypertension worsens
Presence of significant proteinuria
Signs of end organ involvement
There are concerns about fetal wellbeing
Baseline laboratory evaluations to monitor progression
of disease
Crucial that an accurate fluid-balance chart maintained
to ensure that renal impairment detected early