1. Bioinformatics tools to retrieve
Electronical Health Records
Elena H Martínez-Lapiscina1, Xavier Pastor 2, Ekaterina Kotelnikova1,
Lozano Rubí Raimundo2, Artur Conesa 2, Pablo Villoslada1.
1 Neurociencias, IDIBAPS, Barcelona, Spain
2 Informática Médica, Hospital Clinic – UB, Barcelona, Spain

2. Background

3. Background
• Electronical Health Records (EHR) integrated ALL aspects of care over time.
Administrative data
Active Treatment Lists
Clinical text including clinical
course and medical decisions
Ancillary clinical data
Structured information+ -
INVALUABLE
RESORCE
• Electronic Health Records data comprise :
CHALLENGE

4. Advantages
Basic and Clinical
Researchers
EHR
From RCT to Observational studies: Effectiveness and ADR in real conditions
RCT
EHR Real conditions
Hoffman S andPodgurski A; The use and misuse of biomedical data: is bigger really better? Am J Law Med. 2013;39:497-538

5. Advantages
Basic and Clinical
Researchers
EHR
From GWAS to GWLA: Simplifying phenotype stratification
GWAS
Healthy voluntaries Patients
GWLS
Bioinformatics tools + EHR
Hoffman S andPodgurski A; The use and misuse of biomedical data: is bigger really better? Am J Law Med. 2013;39:497-538

6. Advantages
Pharmacovigilance
EHR
Rare ADR or ADR during off-label uses
Identify Drug-Drug interactions
Safety use of drug in special conditions: infancy, pregnancy, liver and kidney failure
Hoffman S andPodgurski A; The use and misuse of biomedical data: is bigger really better? Am J Law Med. 2013;39:497-538

7. Advantages
Healthcare practitioner
EHR
Practice Guidelines
Decision Support-programs
Alert programs for Drugs
Hoffman S andPodgurski A; The use and misuse of biomedical data: is bigger really better? Am J Law Med. 2013;39:497-538

8. Heu vist un extracte de la Presentació:
Bioinformatics tools to retrieve Electronical Health Records
Elena H Martínez-Lapiscina - Xavier Pastor - Ekaterina Kotelnikova - Lozano Rubí Raimundo
Artur Conesa - Pablo Villoslada
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