Which statement provides the most accurate description of the Rpos protein? RpoS is an alternative sigma factor. It is a global regulator that controls the expression of a large set of genes involved in general stress response. RpoS is a regulatory protein. It is an activator, which blocks the transcription of housekeeping genes during stress. Rpos is a housekeeping sigma factor, that controls the expression of the general stress response genes in E.coli. RpoS is a general stress response factor, it is a negative regulator, which controls RNAP. .