An alpha helix acts like a bar magnet. Describe the origin of this effect at the peptide bond and
how this results in a helical dipole. Give an example of how this is used in biology.
2. a) Give the name and amino acid sequence for the polypeptide coded as PDB 1PPT.
b) Generate your own illustration using any molecular visualisation program for the overall fold
of 1PPT.
c) Using the ProtScale tool relate the predictions of the (i) alpha helix/Chou P.Y., Fasman G.D.
and (ii) coil/Deleage G., Roux B. methods to the observed x-ray structure of 1PPT..
An alpha helix acts like a bar magnet- Describe the origin of this eff.pdf
1. An alpha helix acts like a bar magnet. Describe the origin of this effect at the peptide bond and
how this results in a helical dipole. Give an example of how this is used in biology.
2. a) Give the name and amino acid sequence for the polypeptide coded as PDB 1PPT.
b) Generate your own illustration using any molecular visualisation program for the overall fold
of 1PPT.
c) Using the ProtScale tool relate the predictions of the (i) alpha helix/Chou P.Y., Fasman G.D.
and (ii) coil/Deleage G., Roux B. methods to the observed x-ray structure of 1PPT.
