Alexander Bufe: LIAB Antegrade CTO with Bifurcation
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14th Experts Live CTO September 2nd - 3rd, 2022 - Mainz, Germany AGIK Parallel Session - Session 3: The 101 of antegrade approach LIAB Antegrade CTO with Bifurcation Alexander Bufe, Krefeld, Germany Room: West Foyer - Friday 15:15 Chairmen: Michael Behnes, Mannheim, Germany; Felix Woitek, Dresden, Germany
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
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the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
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Auditorium Zubin Mehta - Saturday 8:30 - 10:00
Coordinator:
Roberto Garbo (Turin)
Chairpersons:
Heinz Joachim Büttner (Bad Krozingen - D),
Roberto Diletti (Rotterdam - NL)
Discussants:
Michael Behnes (Mannheim - D),
Giacomo Boccuzzi (Turin),
Alexander Bufe (Krefeld - D),
Salvatore Colangelo (Turin)
Challengers:
Paul Knaapen (Amsterdam - NL),
Gioel Gabrio Secco (Alessandria)
___________________________________________
15th Experts Live CTO,
EUROCTO Club meeting in partnership with the GISE CTO meeting.
September 8th - 9th, 2023
Florence, Italy
Francesco Burzotta: Tips & tricks on radial CTO-PCI
Live Cases from Florence and Rome
From Tor Vergata Hospital, Rome
Operators:
Andrea Gagnor (Turin),
Mohaned Egred (Newcastle - UK),
Daniela Benedetto (Rome)
From Careggi University Hospital, Florence
Operators:
Masahisa Yamane (Tokyo - J),
Stelios Pyxaras (Furth - D),
Carlo Di Mario (Florence)
Flash Highlights
8:30
Tips & tricks on radial CTO-PCI
Francesco Burzotta (Rome)
___________________________________________
PLENARY SESSION
Live Cases from Florence and Rome + Flash Highlights
Auditorium Zubin Mehta - Saturday 8:30 - 10:00
Coordinator:
Roberto Garbo (Turin)
Chairpersons:
Heinz Joachim Büttner (Bad Krozingen - D),
Roberto Diletti (Rotterdam - NL)
Discussants:
Michael Behnes (Mannheim - D),
Giacomo Boccuzzi (Turin),
Alexander Bufe (Krefeld - D),
Salvatore Colangelo (Turin)
Challengers:
Paul Knaapen (Amsterdam - NL),
Gioel Gabrio Secco (Alessandria)
___________________________________________
15th Experts Live CTO,
EUROCTO Club meeting in partnership with the GISE CTO meeting.
September 8th - 9th, 2023
Florence, Italy
Kambis Mashayekhi: EuroCTO Consensus on treatment of Calcified CTO lesion Eur...
AUDITORIUM ZUBIN MEHTA
08/09/2023 04:30 - 05:20
PLENARY SESSION - INTERVENTIONAL CTO & CHIP RESEARCH Best CTO Publications 2022-23 (selected by the Editors of the Cardiology Interventional journals)
Emmanouil S. Brilakis - CTO PCI Outcome associated with poor quality of the d...
16:53
CTO PCI Outcome associated with poor quality of the distal target vessel
Emmanouil Brilakis (Minneapolis - USA)
_____________________________________________
PARALLEL SESSION
Interventional CTO & Chip Research
Best CTO Publications 2022-23 (selected by the Editors of the Cardiology Interventional journals)
Auditorium Zubin Mehta - Friday 16:30 - 17:16
Chairpersons:
Davide Capodanno (Catania),
Carlo Di Mario (Florence),
Giuseppe Tarantini (Padua)
Panelist:
Roberto Diletti (Rotterdam - NL),
Giovanni Esposito (Naples),
Paul Knaapen (Amsterdam - NL),
Maksymilian Opolski (Warsaw - PL)
___________________________________________
15th Experts Live CTO,
EUROCTO Club meeting in partnership with the GISE CTO meeting.
September 8th - 9th, 2023
Florence, Italy
Mario Iannaccone - 2 EuroCTO Consensus on Guide Catheter Extensions JACC Card...
16:33
EuroCTO Consensus on Guide Catheter Extensions JACC Cardiovasc Interventions
Mario Iannaccone (Turin)
_____________________________________________
PARALLEL SESSION
Interventional CTO & Chip Research
Best CTO Publications 2022-23 (selected by the Editors of the Cardiology Interventional journals)
Auditorium Zubin Mehta - Friday 16:30 - 17:16
Chairpersons:
Davide Capodanno (Catania),
Carlo Di Mario (Florence),
Giuseppe Tarantini (Padua)
Panelist:
Roberto Diletti (Rotterdam - NL),
Giovanni Esposito (Naples),
Paul Knaapen (Amsterdam - NL),
Maksymilian Opolski (Warsaw - PL)
___________________________________________
15th Experts Live CTO,
EUROCTO Club meeting in partnership with the GISE CTO meeting.
September 8th - 9th, 2023
Florence, Italy
Javier Escaned: 3 Low contrast complex and CTO PCI
Flash Highlights
15:00
3 Low contrast complex and CTO PCI
Javier Escaned (Madrid - Spain)
___________________________________________
PARALLEL SESSION
Live Cases from Rome + Flash Highlights
Auditorium Zubin Mehta - Friday 15:00 - 16:30
Coordinator:
Andrea Gagnor (Turin)
Chairpersons:
Roberto Diletti (Rotterdam - NL),
Bernward Lauer (Jena - D)
Discussants:
Alessio Gaetano La Manna (Catania),
Eugenio Stabile (Potenza)
Challengers:
Paul Knaapen (Amsterdam - NL),
Alessio Mattesini (Florence)
___________________________________________
15th Experts Live CTO,
EUROCTO Club meeting in partnership with the GISE CTO meeting.
September 8th - 9th, 2023
Florence, Italy
Giuseppe Tarantini: Protect IV and PROTECT-Europe trial
11:35
Protect IV and PROTECT-Europe trial
Giuseppe Tarantini (Padua)
_____________________________________________
PARALLEL SESSION
Cto & Chip Regitries & Trials
Auditorium Zubin Mehta - Friday 11:00 - 12:00
Chairpersons:
Paul Knaapen (Amsterdam - NL),
Gennaro Sardella (Rome)
Discussants:
Björn Billmann (Wolfenbuettel - D),
Laurent Drogul (Nice - F),
Sergey Furkalo (Kiev - UA),
Maciej Lesiak (Poznan - PL)
___________________________________________
15th Experts Live CTO,
EUROCTO Club meeting in partnership with the GISE CTO meeting.
September 8th - 9th, 2023
Florence, Italy
Paul Knaapen: The PROCTOR randomized trial
11:28
The PROCTOR randomized trial
Paul Knaapen (Amsterdam - NL)
_____________________________________________
PARALLEL SESSION
Cto & Chip Regitries & Trials
Auditorium Zubin Mehta - Friday 11:00 - 12:00
Chairpersons:
Paul Knaapen (Amsterdam - NL),
Gennaro Sardella (Rome)
Discussants:
Björn Billmann (Wolfenbuettel - D),
Laurent Drogul (Nice - F),
Sergey Furkalo (Kiev - UA),
Maciej Lesiak (Poznan - PL)
___________________________________________
15th Experts Live CTO,
EUROCTO Club meeting in partnership with the GISE CTO meeting.
September 8th - 9th, 2023
Florence, Italy
John Davies: Update on the ORBITA - CTO trial
11:21
Update on the ORBITA - CTO trial
John Davies (Basildon - UK)
_____________________________________________
PARALLEL SESSION
Cto & Chip Regitries & Trials
Auditorium Zubin Mehta - Friday 11:00 - 12:00
Chairpersons:
Paul Knaapen (Amsterdam - NL),
Gennaro Sardella (Rome)
Discussants:
Björn Billmann (Wolfenbuettel - D),
Laurent Drogul (Nice - F),
Sergey Furkalo (Kiev - UA),
Maciej Lesiak (Poznan - PL)
___________________________________________
15th Experts Live CTO,
EUROCTO Club meeting in partnership with the GISE CTO meeting.
September 8th - 9th, 2023
Florence, Italy
Masahisa Yamane: The Complex CTO Japanese Registry
11:14
The Complex CTO Japanese Registry
Masahisa Yamane (Tokyo - J)
_____________________________________________
PARALLEL SESSION
Cto & Chip Regitries & Trials
Auditorium Zubin Mehta - Friday 11:00 - 12:00
Chairpersons:
Paul Knaapen (Amsterdam - NL),
Gennaro Sardella (Rome)
Discussants:
Björn Billmann (Wolfenbuettel - D),
Laurent Drogul (Nice - F),
Sergey Furkalo (Kiev - UA),
Maciej Lesiak (Poznan - PL)
___________________________________________
15th Experts Live CTO,
EUROCTO Club meeting in partnership with the GISE CTO meeting.
September 8th - 9th, 2023
Florence, Italy
Kambis Mashayekhi: Trends and spin-offs from the EuroCTO Registry
11:00
Trends and spin-offs from the EuroCTO Registry
Kambis Mashayekhi (Lahr - D)
_____________________________________________
PARALLEL SESSION
Cto & Chip Regitries & Trials
Auditorium Zubin Mehta - Friday 11:00 - 12:00
Chairpersons:
Paul Knaapen (Amsterdam - NL),
Gennaro Sardella (Rome)
Discussants:
Björn Billmann (Wolfenbuettel - D),
Laurent Drogul (Nice - F),
Sergey Furkalo (Kiev - UA),
Maciej Lesiak (Poznan - PL)
___________________________________________
15th Experts Live CTO,
EUROCTO Club meeting in partnership with the GISE CTO meeting.
September 8th - 9th, 2023
Florence, Italy
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15th Experts Live CTO - Carlo Di Mario: Conclusions
15th Experts Live CTO - Carlo Di Mario: Conclusions
Shunsuke Matsuno: Progress in dedicated novel CTO material
Shunsuke Matsuno: Progress in dedicated novel CTO material
Jonathan Hill: Role of mechanica support in CTO recanalization
Jonathan Hill: Role of mechanica support in CTO recanalization
Leszek Bryniarski: Mechanical protection in CTO PCI: the Krakow experience
Leszek Bryniarski: Mechanical protection in CTO PCI: the Krakow experience
Sunsuke Matsuno: Intracoronary imaging guidance in CTO practice
Sunsuke Matsuno: Intracoronary imaging guidance in CTO practice
15th Experts Live CTO: Mohamed Ayoub: Aorto-ostial CTO
15th Experts Live CTO: Mohamed Ayoub: Aorto-ostial CTO
15th Experts Live CTO - Claudia Cosgrove: Calcium and CTO
15th Experts Live CTO - Claudia Cosgrove: Calcium and CTO
Gregor Leibundgut Update on microcatheter options and selection
Gregor Leibundgut Update on microcatheter options and selection
Francesco Burzotta: Tips & tricks on radial CTO-PCI
Francesco Burzotta: Tips & tricks on radial CTO-PCI
Kambis Mashayekhi: EuroCTO Consensus on treatment of Calcified CTO lesion Eur...
Kambis Mashayekhi: EuroCTO Consensus on treatment of Calcified CTO lesion Eur...
Emmanouil S. Brilakis - CTO PCI Outcome associated with poor quality of the d...
Emmanouil S. Brilakis - CTO PCI Outcome associated with poor quality of the d...
Mario Iannaccone - 2 EuroCTO Consensus on Guide Catheter Extensions JACC Card...
Mario Iannaccone - 2 EuroCTO Consensus on Guide Catheter Extensions JACC Card...
Javier Escaned: 3 Low contrast complex and CTO PCI
Javier Escaned: 3 Low contrast complex and CTO PCI
Giuseppe Tarantini: Protect IV and PROTECT-Europe trial
Giuseppe Tarantini: Protect IV and PROTECT-Europe trial
Masahisa Yamane: The Complex CTO Japanese Registry
Masahisa Yamane: The Complex CTO Japanese Registry
Kambis Mashayekhi: Trends and spin-offs from the EuroCTO Registry
Kambis Mashayekhi: Trends and spin-offs from the EuroCTO Registry
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Alcohol_Dr. Jeenal Mistry MD Pharmacology.pdf
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
ANATOMY AND PHYSIOLOGY OF URINARY SYSTEM.pptx
Valuable Content of Human Anatomy and Physiology of Urinary system as per PCI Syllabus for Pharmacy and PharmD Students.
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NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
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Non-respiratory Functions of the Lungs.pdf
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdf
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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KDIGO 2024 guidelines for diabetologists
KDIGO guidelines 2024 for evaluation and management of CKD, related to diabetes and management of diabetic kidney disease
Physiology of Chemical Sensation of smell.pdf
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Hemodialysis: Chapter 3, Dialysis Water Unit - Dr.Gawad
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
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Prix Galien International 2024 Forum Program
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- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journey
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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