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ANTI HYPERLIPIDIMIC
DRUGS
UNIVERSITY OF SULAIMANI
COLLEGE OF PHARMACY
2017
PPE Drugs
Gimfibrozil
8/7/2017 University of sulaimany-college of pharmacy 2
1
USES
 Hyperlipidemia
 Hypertriglyceridemia
 Prevention of cardiovascular disease
Strength | 600mg
Brand name : LOPID
SIDE EFFECTS
 NVD
 Dyspepsia
 Abdominal pain
Dosage | Tablet
Simvastatin
8/7/2017 University of sulaimany-college of pharmacy 3
2
USES
 Hypercholertolemia
 Prevention of cardiovascular disease
Strength| (5/10/20/40/80) mg
Brand name : ZOCOR
SIDE EFFECTS
 CPK Elevation
 URTI
 Abdominal pain
 Headache
 Myalgia
Dosage| Tablet
DRUGS WORKING ON CNS
UNIVERSITY OF SULAIMANI
COLLEGE OF PHARMACY
2017
PPE Drugs
GABAPENTIN
8/7/2017 University of sulaimany-college of pharmacy 5
1
USES
 Partial Seizures
 Restless leg syndrome
 Insomnia
 Diabetic Neuropathy
Strength| (100/300/400) mg
Brand name : Neurontin
SIDE EFFECTS
 Dizziness
 Fatigue
 Drowsiness
 Tremor
 Ataxia
 Diplopia
Dosage| Tablet/Capsule/Syrup
Carbamazipine
8/7/2017 University of sulaimany-college of pharmacy 6
2
USES
 Epilepsy
 Restless leg syndrome
 Bipolar mania
 Schizophrenia
Strength| (100/200/300mg Tab) (100/5
syrup) (10mg/ml IV)
Brand name : Tegretol
SIDE EFFECTS
 Dizziness
 Fatigue
 Drowsiness
 Ataxia
 NV
 Dry mouth
Dosage| Tablet/Capsule/Syrup/IV
Sertraline
8/7/2017 University of sulaimany-college of pharmacy 7
3
USES
 Major depressive disorder
 Obsessive compulsive disorder
 Panic Disorder
 Social anxiety disorder
Strength| (25/50/100mg Tab) (20mg/ml
syrup)
Brand name : Zoloft
SIDE EFFECTS
 Head ache
 Fatigue
 Dizziness
 Insomnia
 NVD
 Dry mouth
Dosage| Tablet/Syrup
Antibiotics
UNIVERSITY OF SULAIMANI
COLLEGE OF PHARMACY
2017
PPE Drugs
Rifampicin
8/7/2017 University of sulaimany-college of pharmacy 9
1
USES
 Tuberculosis
 Brucellosis
 Haemophilus influenza
 Neisseria meningitis
 Staph infection
Strength| (150/300mg cap) (600mg
injectable powder)
Brand name : RIFADIN
SIDE EFFECTS
 NVD
 Anorexia
 Rash /fever
 Pancreatitis
 Elevated LFT( liver function Test )
Dosage| Capsule /Injectable powder
Doxycyclin
8/7/2017 University of sulaimany-college of pharmacy 10
2
USES
 Periodental disese & Anthrax
 RTI & Brucellosis
 Amoebiasis & Cholera
 Chlamydia & STD
Strength| (50/75/100/150mg )
Brand name : Monodox,Doxycin
SIDE EFFECTS
 NVD
 Staining of teeth
 Rash /sensitivity to light
 Sore mouth
 itching of rectum,vagina
Dosage| Tab/Cap/syrup/suspension
Ciprofloxacin
8/7/2017 University of sulaimany-college of pharmacy 11
3
USES
 Sinusitis /anthrax
 LRTI
 Bone/joint infection
 Skin infection
 Chronic bacterial prostatitis
 Intra abdominal infection
 UTI / urethral infection
Strength| (100/250/500/750mgTab )
(250 mg or 500 mg /5ml )
Brand name : Cipro
SIDE EFFECTS
 NVD – Abdominal pain – dizziness
 Rash
 Joint movement problem
Dosage| Tab/IV/suspension
Azithromycin
8/7/2017 University of sulaimany-college of pharmacy 12
4
USES
 Acute bacterial sinusitis
 Pharyngitis/tonsillitis/otitis
 Community acquired pneumonia
 Skin infection
 Bacterial STD infection
 Endocarditis
Strength| (250/500/600mgTab )
(100 mg or 200 mg /5ml )
Brand name : Zithromax,Zmax
SIDE EFFECTS
 NVD – Abdominal pain - ringing in ears
 Loose stool
 Flatulence/cramping
Dosage| Tab/suspension
NSAIDS
UNIVERSITY OF SULAIMANI
COLLEGE OF PHARMACY
2017
PPE Drugs
Diclofenac
8/7/2017 University of sulaimany-college of pharmacy 14
1
USES
 RA (rheumatoid arthritis)
 OA(Osteoarthritis)
 Pain
 Ankylosing spondylitis
 Migraine
 Dysmenorrhea
Strength| (25/50/75mg/100mg tab)
Brand name : Voltaren-Cataflam-
Zorvolex
SIDE EFFECTS
 NVD – Abdominal pain –mild heartburn
 Dry mouth
 Dizziness
 Stuffiness
 Elevated BP
Dosage| Tab/Capsule /powder/IV/IM
Meloxicam
8/7/2017 University of sulaimany-college of pharmacy 15
2
USES
 RA (rheumatoid arthritis)
 OA(Osteoarthritis)
Strength| (7.5/15mg tab)
Brand name : Mobic
SIDE EFFECTS
 NVD – Abdominal pain
 Edema
 GI ulceration /Anemia
 Upper respiratory infection/ Shortness
of breath
 Dizziness
 MI/CHF
Dosage| Tab/Capsule /Suspension
Aspirin
8/7/2017 University of sulaimany-college of pharmacy 16
3
USES
 Anticoagulant
 Pain
 Fever
 CAD (coronary artery disease)
 OA/RA
Strength| (81/325/650/500/1000 tab)
Brand name : ASA,ZORPRIN
SIDE EFFECTS
 NVD – Abdominal pain
 Edema
 GI ulceration /Anemia/bloody black stool
 Upper respiratory infection/ Shortness
of breath
 Dizziness
 MI/CHF
Dosage| Tab/Capsule
Indomethacin
8/7/2017 University of sulaimany-college of pharmacy 17
4
USES
 OA/RA
 Gouty arthritis
 Pain
 Bursitis/Tendinitis
Strength| (20/25/40/50/75 cap)
25/5ml (Oral.Susp)
Supp. 50 mg
Brand name : Indocin
SIDE EFFECTS
 NVD – Abdominal pain-head ache
 Dizziness
 Elevated LFT
 Jaundice
 Transient renal insufficiency
Dosage| Capsule /OS/supp/powder for inj
Ibuprofen
8/7/2017 University of sulaimany-college of pharmacy 18
5
USES
 OA/RA
 Pain/Fever/Dysmenorrhea
Strength| (100/200/400/600/800 tab)
200mg (cap)
100/5ml (Oral.Susp)
Brand name : Advil
SIDE EFFECTS
 NVD – Abdominal pain-head ache –heart
burn
 Dizziness
 Rash
 tinnitis
Dosage| Tablet /Capsule /OS
Mefenamic acid
8/7/2017 University of sulaimany-college of pharmacy 19
6
USES
 Pain/Fever/Dysmenorrhea
Strength| (250/500mg Cap)
Brand name : Ponstan
SIDE EFFECTS
 NVD – Abdominal pain-head ache –heart
burn
 Dizziness
 Rash
 tinnitis
Dosage| Capsule /OS
Antihypertensive
Drugs
UNIVERSITY OF SULAIMANI
COLLEGE OF PHARMACY
2017
PPE Drugs
Amlodipine
8/7/2017 University of sulaimany-college of pharmacy 21
1
USES
 Coronary artery disease
 Angina
 Hypertension
Strength| (2.5/5/10mgtab)
Brand name :Norvasc
SIDE EFFECTS
 Headache –fatigue
 Edema / pulmonary edema
 Gingival hyperplasia
Dosage| Tab
Methyldopa
8/7/2017 University of sulaimany-college of pharmacy 22
2
USES
 Hypertension crisis
 Hypertension in pregnancy
 Hypertension
Strength| (250/500mg)
Inj soln. 50mg/ml
Brand name :Aldomet
SIDE EFFECTS
 NVD-headache-dry mouth-stuffy nose
 Weight gain
 Weakness
 Dizziness
 Joint,muscle pain
Dosage| Tab , inj solution
Candesartan
8/7/2017 University of sulaimany-college of pharmacy 23
3
USES
 Chronic Heart failure
 Hypertension
Strength| (4/8/16/32mg)
Brand name :Atacand
SIDE EFFECTS
 runny or stuffy nose, sore throat, cough
 stomach pain, diarrhea
 back pain , joint pain
 headache, dizziness , tired feeling
Dosage| Tab
Furosemide
8/7/2017 University of sulaimany-college of pharmacy 24
4
USES
 Edema
 Resistant Hypertension
 acute pulmonary edema
 Hyperkalemia
 Hypomagnesemia
Strength| (20/40/80mg tab )
Inj.soln 10mg/ml
Brand name :Lasix Dosage| Tab/oral solution /inj soln
SIDE EFFECTS
 Hyperuricemia
 Hypokalemia
 Hearing loss /ringing in ear
 Severe Epigastric pain
Spironolactone
8/7/2017 University of sulaimany-college of pharmacy 25
5
USES
 Congestive heart failure
 Essential hypertension
 Edema
 Hypokalemia
Strength| (25/50/100mg tab )
Brand name :Aldactone Dosage|Tab
SIDE EFFECT
 NVD –Stomach pain and cramps –
dizziness – head ache
 Dry mouth / thirst
 Gynecomastia
 Irregular menstrual periods
 Erectile dysfunction
GIT DRUGS
UNIVERSITY OF SULAIMANI
COLLEGE OF PHARMACY
2017
PPE Drugs
Omeprazole
8/7/2017 University of sulaimany-college of pharmacy 27
1
USES
 Gastric Ulcer
 Duodenal Ulcer
 GERD
 H-pylori induced ulcer
 Heart burn
Strength| 10,20,40 mg cap )
2mg/ml (Suspension)
20mg (Tab)
Brand name :Prilosec , Losec
SIDE EFFECTS
 NVD-stomach pain
 Head ache , fever
 Stuffynose
Dosage| Cap , Suspension, Tab
Domperidone
8/7/2017 University of sulaimany-college of pharmacy 28
2
USES
 Dyspepsia
 Nausea and Vomiting
Strength| 10,20 mg tab
Brand name :Motillium
SIDE EFFECTS
 Drymoth
 Breast pain
 Gyncomastia
 Galactorrhea
 Cardiac dysarrythmia
Dosage| Tab
Other Drugs
UNIVERSITY OF SULAIMANI
COLLEGE OF PHARMACY
2017
PPE Drugs
Hydroxyzine
8/7/2017 University of sulaimany-college of pharmacy 30
1
USES
 Anxiety
 Preoperative sedation
 Nausea, vomiting
 Allergy
Strength| 10,25 , 50 mg tab,
Cap 25 ,50,100 mg
Syrup 10mg /5ml
Inj 25,50mg/5ml
Brand name : Vistaril
SIDE EFFECTS
 Dry mouth
 CNS |Drowsiness
Tremor , convulsion
Dosage| Tab /cap /oral suspension /inj.
Tranexamic acid
8/7/2017 University of sulaimany-college of pharmacy 31
2
USES
 Antifibrinolytic
 Heavy menstural bleeding
 Surgery | ex :Total knee replacement
surgery (to prevent blood loss)
 Antifibrinolytic
 Hereditary angioedema
Strength| 500 , 650 mg tab
100mg/ml
Brand name :Cyklokapron
SIDE EFFECTS
 Head ache –back pain –fatigue
 Nasal sinus symptoms
 Abdominal pain
 Muscular pain
Dosage| Tab ,inj
Montelucast
8/7/2017 University of sulaimany-college of pharmacy 32
3
USES
 Asthma
 Exercise induced bronchospasm
 Allergic rhinitis
Strength| 4,5,10 mg tab
Brand name : Singulair
SIDE EFFECTS
 Head ache
 Abdominal pain
 Laryngitis,phartyngitis
 Eczema
Dosage| Tab (chewable)

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Antihyperlipidemic and CNS drugs PPT

  • 1. ANTI HYPERLIPIDIMIC DRUGS UNIVERSITY OF SULAIMANI COLLEGE OF PHARMACY 2017 PPE Drugs
  • 2. Gimfibrozil 8/7/2017 University of sulaimany-college of pharmacy 2 1 USES  Hyperlipidemia  Hypertriglyceridemia  Prevention of cardiovascular disease Strength | 600mg Brand name : LOPID SIDE EFFECTS  NVD  Dyspepsia  Abdominal pain Dosage | Tablet
  • 3. Simvastatin 8/7/2017 University of sulaimany-college of pharmacy 3 2 USES  Hypercholertolemia  Prevention of cardiovascular disease Strength| (5/10/20/40/80) mg Brand name : ZOCOR SIDE EFFECTS  CPK Elevation  URTI  Abdominal pain  Headache  Myalgia Dosage| Tablet
  • 4. DRUGS WORKING ON CNS UNIVERSITY OF SULAIMANI COLLEGE OF PHARMACY 2017 PPE Drugs
  • 5. GABAPENTIN 8/7/2017 University of sulaimany-college of pharmacy 5 1 USES  Partial Seizures  Restless leg syndrome  Insomnia  Diabetic Neuropathy Strength| (100/300/400) mg Brand name : Neurontin SIDE EFFECTS  Dizziness  Fatigue  Drowsiness  Tremor  Ataxia  Diplopia Dosage| Tablet/Capsule/Syrup
  • 6. Carbamazipine 8/7/2017 University of sulaimany-college of pharmacy 6 2 USES  Epilepsy  Restless leg syndrome  Bipolar mania  Schizophrenia Strength| (100/200/300mg Tab) (100/5 syrup) (10mg/ml IV) Brand name : Tegretol SIDE EFFECTS  Dizziness  Fatigue  Drowsiness  Ataxia  NV  Dry mouth Dosage| Tablet/Capsule/Syrup/IV
  • 7. Sertraline 8/7/2017 University of sulaimany-college of pharmacy 7 3 USES  Major depressive disorder  Obsessive compulsive disorder  Panic Disorder  Social anxiety disorder Strength| (25/50/100mg Tab) (20mg/ml syrup) Brand name : Zoloft SIDE EFFECTS  Head ache  Fatigue  Dizziness  Insomnia  NVD  Dry mouth Dosage| Tablet/Syrup
  • 8. Antibiotics UNIVERSITY OF SULAIMANI COLLEGE OF PHARMACY 2017 PPE Drugs
  • 9. Rifampicin 8/7/2017 University of sulaimany-college of pharmacy 9 1 USES  Tuberculosis  Brucellosis  Haemophilus influenza  Neisseria meningitis  Staph infection Strength| (150/300mg cap) (600mg injectable powder) Brand name : RIFADIN SIDE EFFECTS  NVD  Anorexia  Rash /fever  Pancreatitis  Elevated LFT( liver function Test ) Dosage| Capsule /Injectable powder
  • 10. Doxycyclin 8/7/2017 University of sulaimany-college of pharmacy 10 2 USES  Periodental disese & Anthrax  RTI & Brucellosis  Amoebiasis & Cholera  Chlamydia & STD Strength| (50/75/100/150mg ) Brand name : Monodox,Doxycin SIDE EFFECTS  NVD  Staining of teeth  Rash /sensitivity to light  Sore mouth  itching of rectum,vagina Dosage| Tab/Cap/syrup/suspension
  • 11. Ciprofloxacin 8/7/2017 University of sulaimany-college of pharmacy 11 3 USES  Sinusitis /anthrax  LRTI  Bone/joint infection  Skin infection  Chronic bacterial prostatitis  Intra abdominal infection  UTI / urethral infection Strength| (100/250/500/750mgTab ) (250 mg or 500 mg /5ml ) Brand name : Cipro SIDE EFFECTS  NVD – Abdominal pain – dizziness  Rash  Joint movement problem Dosage| Tab/IV/suspension
  • 12. Azithromycin 8/7/2017 University of sulaimany-college of pharmacy 12 4 USES  Acute bacterial sinusitis  Pharyngitis/tonsillitis/otitis  Community acquired pneumonia  Skin infection  Bacterial STD infection  Endocarditis Strength| (250/500/600mgTab ) (100 mg or 200 mg /5ml ) Brand name : Zithromax,Zmax SIDE EFFECTS  NVD – Abdominal pain - ringing in ears  Loose stool  Flatulence/cramping Dosage| Tab/suspension
  • 13. NSAIDS UNIVERSITY OF SULAIMANI COLLEGE OF PHARMACY 2017 PPE Drugs
  • 14. Diclofenac 8/7/2017 University of sulaimany-college of pharmacy 14 1 USES  RA (rheumatoid arthritis)  OA(Osteoarthritis)  Pain  Ankylosing spondylitis  Migraine  Dysmenorrhea Strength| (25/50/75mg/100mg tab) Brand name : Voltaren-Cataflam- Zorvolex SIDE EFFECTS  NVD – Abdominal pain –mild heartburn  Dry mouth  Dizziness  Stuffiness  Elevated BP Dosage| Tab/Capsule /powder/IV/IM
  • 15. Meloxicam 8/7/2017 University of sulaimany-college of pharmacy 15 2 USES  RA (rheumatoid arthritis)  OA(Osteoarthritis) Strength| (7.5/15mg tab) Brand name : Mobic SIDE EFFECTS  NVD – Abdominal pain  Edema  GI ulceration /Anemia  Upper respiratory infection/ Shortness of breath  Dizziness  MI/CHF Dosage| Tab/Capsule /Suspension
  • 16. Aspirin 8/7/2017 University of sulaimany-college of pharmacy 16 3 USES  Anticoagulant  Pain  Fever  CAD (coronary artery disease)  OA/RA Strength| (81/325/650/500/1000 tab) Brand name : ASA,ZORPRIN SIDE EFFECTS  NVD – Abdominal pain  Edema  GI ulceration /Anemia/bloody black stool  Upper respiratory infection/ Shortness of breath  Dizziness  MI/CHF Dosage| Tab/Capsule
  • 17. Indomethacin 8/7/2017 University of sulaimany-college of pharmacy 17 4 USES  OA/RA  Gouty arthritis  Pain  Bursitis/Tendinitis Strength| (20/25/40/50/75 cap) 25/5ml (Oral.Susp) Supp. 50 mg Brand name : Indocin SIDE EFFECTS  NVD – Abdominal pain-head ache  Dizziness  Elevated LFT  Jaundice  Transient renal insufficiency Dosage| Capsule /OS/supp/powder for inj
  • 18. Ibuprofen 8/7/2017 University of sulaimany-college of pharmacy 18 5 USES  OA/RA  Pain/Fever/Dysmenorrhea Strength| (100/200/400/600/800 tab) 200mg (cap) 100/5ml (Oral.Susp) Brand name : Advil SIDE EFFECTS  NVD – Abdominal pain-head ache –heart burn  Dizziness  Rash  tinnitis Dosage| Tablet /Capsule /OS
  • 19. Mefenamic acid 8/7/2017 University of sulaimany-college of pharmacy 19 6 USES  Pain/Fever/Dysmenorrhea Strength| (250/500mg Cap) Brand name : Ponstan SIDE EFFECTS  NVD – Abdominal pain-head ache –heart burn  Dizziness  Rash  tinnitis Dosage| Capsule /OS
  • 21. Amlodipine 8/7/2017 University of sulaimany-college of pharmacy 21 1 USES  Coronary artery disease  Angina  Hypertension Strength| (2.5/5/10mgtab) Brand name :Norvasc SIDE EFFECTS  Headache –fatigue  Edema / pulmonary edema  Gingival hyperplasia Dosage| Tab
  • 22. Methyldopa 8/7/2017 University of sulaimany-college of pharmacy 22 2 USES  Hypertension crisis  Hypertension in pregnancy  Hypertension Strength| (250/500mg) Inj soln. 50mg/ml Brand name :Aldomet SIDE EFFECTS  NVD-headache-dry mouth-stuffy nose  Weight gain  Weakness  Dizziness  Joint,muscle pain Dosage| Tab , inj solution
  • 23. Candesartan 8/7/2017 University of sulaimany-college of pharmacy 23 3 USES  Chronic Heart failure  Hypertension Strength| (4/8/16/32mg) Brand name :Atacand SIDE EFFECTS  runny or stuffy nose, sore throat, cough  stomach pain, diarrhea  back pain , joint pain  headache, dizziness , tired feeling Dosage| Tab
  • 24. Furosemide 8/7/2017 University of sulaimany-college of pharmacy 24 4 USES  Edema  Resistant Hypertension  acute pulmonary edema  Hyperkalemia  Hypomagnesemia Strength| (20/40/80mg tab ) Inj.soln 10mg/ml Brand name :Lasix Dosage| Tab/oral solution /inj soln SIDE EFFECTS  Hyperuricemia  Hypokalemia  Hearing loss /ringing in ear  Severe Epigastric pain
  • 25. Spironolactone 8/7/2017 University of sulaimany-college of pharmacy 25 5 USES  Congestive heart failure  Essential hypertension  Edema  Hypokalemia Strength| (25/50/100mg tab ) Brand name :Aldactone Dosage|Tab SIDE EFFECT  NVD –Stomach pain and cramps – dizziness – head ache  Dry mouth / thirst  Gynecomastia  Irregular menstrual periods  Erectile dysfunction
  • 26. GIT DRUGS UNIVERSITY OF SULAIMANI COLLEGE OF PHARMACY 2017 PPE Drugs
  • 27. Omeprazole 8/7/2017 University of sulaimany-college of pharmacy 27 1 USES  Gastric Ulcer  Duodenal Ulcer  GERD  H-pylori induced ulcer  Heart burn Strength| 10,20,40 mg cap ) 2mg/ml (Suspension) 20mg (Tab) Brand name :Prilosec , Losec SIDE EFFECTS  NVD-stomach pain  Head ache , fever  Stuffynose Dosage| Cap , Suspension, Tab
  • 28. Domperidone 8/7/2017 University of sulaimany-college of pharmacy 28 2 USES  Dyspepsia  Nausea and Vomiting Strength| 10,20 mg tab Brand name :Motillium SIDE EFFECTS  Drymoth  Breast pain  Gyncomastia  Galactorrhea  Cardiac dysarrythmia Dosage| Tab
  • 29. Other Drugs UNIVERSITY OF SULAIMANI COLLEGE OF PHARMACY 2017 PPE Drugs
  • 30. Hydroxyzine 8/7/2017 University of sulaimany-college of pharmacy 30 1 USES  Anxiety  Preoperative sedation  Nausea, vomiting  Allergy Strength| 10,25 , 50 mg tab, Cap 25 ,50,100 mg Syrup 10mg /5ml Inj 25,50mg/5ml Brand name : Vistaril SIDE EFFECTS  Dry mouth  CNS |Drowsiness Tremor , convulsion Dosage| Tab /cap /oral suspension /inj.
  • 31. Tranexamic acid 8/7/2017 University of sulaimany-college of pharmacy 31 2 USES  Antifibrinolytic  Heavy menstural bleeding  Surgery | ex :Total knee replacement surgery (to prevent blood loss)  Antifibrinolytic  Hereditary angioedema Strength| 500 , 650 mg tab 100mg/ml Brand name :Cyklokapron SIDE EFFECTS  Head ache –back pain –fatigue  Nasal sinus symptoms  Abdominal pain  Muscular pain Dosage| Tab ,inj
  • 32. Montelucast 8/7/2017 University of sulaimany-college of pharmacy 32 3 USES  Asthma  Exercise induced bronchospasm  Allergic rhinitis Strength| 4,5,10 mg tab Brand name : Singulair SIDE EFFECTS  Head ache  Abdominal pain  Laryngitis,phartyngitis  Eczema Dosage| Tab (chewable)